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    News and Articles on Women's Health Initiative

    Archives: Women's Health Initiative

    Attend Religious Services, Live Longer  Nov 30, 2008
    Researchers evaluated 92,395 postmenopausal women participating in the Women's Health Initiative Observational Study, a national, multi-ethnic, long-term study aimed at addressing women's health issues funded by the National Institutes of Health. The women, all between the ages of 50 and 79, answered questions about their behaviors, health, and religious practices. (CBS News)

    Estrogen Therapy Could Be Dangerous For Women With Existing Heart Risk  Nov 29, 2008
    28, 2008) Hormone therapy could accentuate certain pre-existing heart disease risk factors and a heart health evaluation should become the norm when considering estrogen replacement, new research suggests. The research also showed that in women without existing atherosclerosis, hormone therapy use included some positive effects on lipids but also some negative effects related to heart health, said MaryFran Sowers, lead researcher and professor of epidemiology at the University of Michigan School... (Science Daily)

    Religion may help extend your life, study says  Nov 27, 2008
    The study participants came from the large Women's Health Initiative observational study, and included nearly 95,000 women from all over the United States. The women were all between 50 and 79 years old at the start of the study. (AZCentral -- News)

    Ginkgo biloba appears to have no effect on dementia  Nov 26, 2008
    The researchers used information from the Women's Health Initiative, a long-term study looking at women 50 to 79 at 40 locations around the United States. The researchers also looked to see if religious observance played a role in reducing heart disease. (International Herald Tribune -- Health)

    Calcium Plus Vitamin D Supplementation Is Not Associated With A Reduced Breast Cancer Risk  Nov 23, 2008
    To test this possibility, researchers evaluated breast cancer incidence as a secondary endpoint in the Women's Health Initiative study in 36,282 postmenopausal women who were randomly assigned to take 1,000 mg of calcium plus 400 IU of vitamin D daily or to daily placebo. (The primary endpoint of the study was effect of the supplements on hip fracture. (Science Daily)

    Attending Religious Services Sharply Cuts Risk Of Death, Study Suggests  Nov 21, 2008
    D., professor of epidemiology and population health at Einstein, as an ancillary study of the Women's Health Initiative (WHI) ... Schnall et al. The relationship between religion and cardiovascular outcomes and all-cause mortality in the women's health initiative observational study. (Science Daily)

    Attending Religious Services Cuts Death Risk  Nov 20, 2008
    D., professor of epidemiology and population health at Einstein, as an ancillary study of the Women's Health Initiative (WHI). The WHI is a national, long-term study aimed at addressing womens health issues and funded by the National Institutes of Health. (Newsmax)

    Supplements Don't Reduce Breast Cancer Risk  Nov 13, 2008
    In the Women's Health Initiative study, 36,282 participants were randomly assigned to receive calcium 1000 milligrams plus vitamin D 400 IU daily or placebo for 7 years, on average, to determine the effect of these supplements on hip fractures. The supplements' effect on invasive breast cancer was a secondary endpoint of the study. (MEDLINEplus)

    Tibolone in Older Postmenopausal Women  Nov 13, 2008
    2 In analyses combining clinical-trial and observational-study cohorts, the Women's Health Initiative (WHI) showed that a decreased risk of breast cancer. . (New England Journal of Medicine)

    No breast cancer benefit from vitamins  Nov 12, 2008
    The study - part of the massive Women's Health Initiative - followed more than 36,000 post-menopausal women who were randomly assigned to take calcium and vitamin D supplements or a placebo. The researchers were mainly interested to see whether the supplements would make a difference in their incidence of hip fracture, but breast cancer was a secondary outcome they studied. (Boston Globe)

    BETTER LIFE: More news on keeping your heart healthy  Nov 11, 2008
    Women's Health Initiative scientists write that they found no evidence of an increased risk of heart disease in hormone users whose ratio of LDL, or "bad" cholesterol, to HDL, or "good" cholesterol was lower than 2. 5. (USA Today -- Money)

    Calcium/Vitamin D Pills Won't Lower Blood Pressure  Nov 8, 2008
    As part of the Women's Health Initiative, the research team studied the effects of 1000 milligrams calcium plus 400 international units vitamin D3, or placebo, in women 50 to 79 years of age. There were 18,000 women in each study group. (MEDLINEplus)

    Pa. Judge Denies Another Breast Cancer-HRT Claim  Nov 4, 2008
    Blaylock argued that her claim wasn't time-barred because she filed her claim within two years of the publication of the findings from the Women's Health Initiative study July 9, 2002, which received far-reaching publicity. The study was discontinued early because of the finding that HRT increased the risk of coronary heart disease and invasive breast cancer, Tereshko wrote in his summary judgment opinion in Coleman. (Law.com)

    New Hormone Data Can Predict Menopause Within A Year  Oct 30, 2008
    30, 2008) For many women, including the growing number who choose later-in-life pregnancy, predicting their biological clock's relation to the timing of their menopause and infertility is critically important. Now, investigators from the University of Michigan have provided new information about hormonal biomarkers that can address the beginning of the menopause transition. (Science Daily)

    Obesity Explains Ethnic Arthritis Differences  Oct 20, 2008
    Among 146,494 women participating in the Women's Health Initiative -- an ongoing study of an ethnically diverse group of healthy postmenopausal women -- 44 percent had been diagnosed with osteoarthritis (degeneration of the joints), the most common form of arthritis. These women were older and less active than their arthritis-free peers, and were also less educated, poorer, and heavier, Nicole C. Wright and colleagues from the University of Arizona in Tucson Wright report in the Journal of the... (Newsmax)

    Smoking Increases Risk for Aortic Aneurysm  Oct 18, 2008
    Researchers out of the VA Medical Center in Minneapolis looked at the potential risk factors for either needing to undergo the repair of an aortic aneurysm or having one burst among over 160,000 postmenopausal women over 40 who were participating in the Women's Health Initiative. They followed the women for an average of nearly eight years. (Insider Medicine)

    Abdominal Aortic Aneurysm More Likely In Women Who Smoke  Oct 18, 2008
    " Abdominal aortic aneurysm events in the women's health initiative: cohort study Frank A Lederle, Joseph C Larson, Karen L Margolis, Matthew A Allison, Matthew S Freiberg, Barbara B Cochrane, William F Graettinger, J David Curb BMJ (2008). 337:a1724 doi:10.1136/bmj.a1724 Written by: Peter M Crosta Copyright: Medical News Today Not to be reproduced without permission of Medical News Today Please rate this article: (Hover over the stars then click to rate) Patient / Public: or Health... (Medical News Today)

    Women Smokers Prone to Dangerous Blood Vessel Condition  Oct 17, 2008
    That's the conclusion of the latest data from the Women's Health Initiative, the landmark trial most noted for the 2002 finding that hormone replacement therapy increases the risk of heart problems. The new finding on the condition called abdominal aortic aneurysm comes from an analysis led by Dr. Frank Lederle, an internist at the Veterans Administration Medical Center in Minneapolis and a professor of medicine at the University of Minnesota. (MEDLINEplus)

    Women's heart ills are often dismissed  Oct 14, 2008
    "We know that there is a delay in diagnosing coronary heart disease in women, and this is an important step forward in understanding why," said Alexandra Lansky, an associate professor at Columbia University College of Physicians and Surgeons and director of the Women's Health Initiative at the Cardiovascular Research Foundation in New York. Copyright 2008 Globe Newspaper Company. (Boston Globe)

    Study reveals that signs of heart disease are attributed to stress more frequently in women than men  Oct 13, 2008
    "We know that there is a delay in diagnosing CHD in women and this is an important step forward in understanding why," said Alexandra J. Lansky, M.D., director of the Women's Health Initiative at CRF, director of Clinical Services at the Center for Interventional Vascular Therapy, a cardiologist at NewYork-Presbyterian Hospital/Columbia University Medical Center, and an associate professor of clinical medicine at Columbia University College of Physicians and Surgeons. The investigation "Gender... (EurekAlert!)

    Timing, Dosage of HRT Affect Chances of Heart Trouble  Oct 3, 2008
    WEDNESDAY, Oct. 1 (HealthDay News) -- The largest observational study of hormone replacement therapy since the landmark Women's Health Initiative finds that how and when women take hormone replacement therapy affects their heart attack risk ... A section of the U.S. government-sponsored Women's Health Initiative (WHI), which was designed to look at health issues in postmenopausal women, was halted in 2002, when U.S. researchers found that HRT led to an increased risk of adverse events that... (MEDLINEplus)

    Estrogen Reduces Risk Of Fracture After Menopause, Study Suggests  Sep 22, 2008
    8, 2007) Secondary analyses of findings from the Women's Health Initiative suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to ... 4, 2007) Five years ago this summer the National Institutes of Health's stopped early a major portion of the Women's Health Initiative (WHI), a large and ambitious study to address the most common causes of. (Science Daily)

    Hormone Replacement Therapy Improves Sleep, Sexuality And Joint Pain In Older Women  Aug 24, 2008
    "For most women with significant menopause symptoms the benefits of HRT outweigh the risks. The latest analyses of the main long-term randomized control trial of HRT (The Women's Health Initiative) show that breast cancer is not increased by oestrogen-only HRT and is only increased in women using combined oestrogen and progestogen HRT after seven years of use. This increased risk is less than 0.1% per year of use. "If a woman feels that HRT is needed for quality of life, then doctors can find... (Science Daily)

    Hormone Replacement Therapy After Menopause Reduces Symptoms  Aug 23, 2008
    Hormone replacement therapy has been under major scrutiny since the Women's Health Initiative (WHI) study was stopped in 2002 because of increases in blood clots, heart disease, stroke and breast cancer risk in women initiating HRT long after menopause. MacLennan's study (dubbed the WISDOM study), which began in 1999 and was originally intended to follow women for up to 10 years on HRT, was also stopped after the WHI findings were released due to concerns that the risks of HRT might outweigh the... (MEDLINEplus)

    Newsweek: Pros of early hormone therapy for women  Aug 22, 2008
    But in 2002, a massive federal study called the Women's Health Initiative (WHI) was halted early because researchers reported that taking estrogen actually increased the risk of breast cancer and stroke. The WHI was a more scientifically reliable clinical study (with a control group) and it contradicted the results of earlier observational studies, which simply followed women over the years. (MSNBC -- Health)

    Bigger Belly May Up Smokers' Lung Cancer Risk  Aug 21, 2008
    To better understand the relationship, he and his colleagues looked at data from the Women's Health Initiative. Over the course of 8 years, 1,365 of the study's 161,809 participants developed lung cancer. (MEDLINEplus)

    TODAY, Aug. 16  Aug 16, 2008
    -- Dr. Damon T. Arnold, MD., M.P.H., Director of the Illinois Department of Public Health, will announce a statewide Women's Health Initiative at 11 a.m. in room 307 at the Fulton County Health Department, 700 E. Oak Street, Canton. -- The Ad Hoc Committee to Determine Capital Projects and Long Range Planning for Fulton County will meet at 6 p.m. in room 307 of the Fulton County Health Department, 700 E. Oak St., Canton. (Canton Daily Ledger, IL)

    KV Pharmaceutical Company Reports Fiscal 2009 First Quarter Results  Aug 12, 2008
    The Women's Health Initiative (WHI) estrogen-alone substudy reported increased risks of stroke and deep vein thrombosis (DVT) in postmenopausal women (50 to 79 years of age) during 6 ... The Women's Health Initiative Memory Study (WHIMS), a substudy of the WHI, reported increased risk of developing probable dementia in postmenopausal women 65 years of age or older during 5. (PR Newswire)

    Dietary Factors Appear To Be Associated With Diabetes Risk  Jul 30, 2008
    D., of the Women's Health Initiative, Fred Hutchison Cancer Research Center, Seattle, and colleagues studied the effects of eating a low-fat diet on diabetes risk in 48,835 post-menopausal women. From 1993 to 2005, 29,294 of the women were randomly assigned to continue eating their usual diet while 19,541 were given a low-fat (20 percent of calories from fat) diet with increased levels of fruits, vegetables and whole grains. (Science Daily)

    Exposure To Bad Air Raises Blood Pressure, Study Shows  Jul 30, 2008
    27, 2007) According to researchers studying postmenopausal women in the Women's Health Initiative, prehypertension exists in about 40 percent of postmenopausal women and it is associated with a 58 percent. . (Science Daily)

    Diet Key to Diabetes Risk  Jul 30, 2008
    In a third study, Lesley F. Tinker, from the Women's Health Initiative at the Fred Hutchison Cancer Research Center in Seattle, and colleagues found no significant reduction in the risk of developing diabetes among women on a low-fat diet. However, the low-fat diet did increase weight loss, which can result in fewer cases of type 2 diabetes. (MEDLINEplus)

    Bone Density Predicts Chances of Breast Cancer  Jul 29, 2008
    This study, led by researchers at the University of Arizona, Tucson, incorporated Gail scores and hip BMD information on almost 10,000 postmenopausal women participating in the Women's Health Initiative. After an average of almost nine years of follow-up, women with a high Gail score were, overall, 35 percent more likely to develop breast cancer. (Health-Finder)

    Hip bone density helps predict breast cancer risk  Jul 28, 2008
    To investigate these relationships, Dr. Zhao Chen of the University of Arizona Mel and Enid Zuckerman College of Public Health and her colleagues studied approximately 10,000 post-menopausal women (average age 63) taking part in the Women's Health Initiative, a study conducted in 40 clinical centers throughout the United States and supported by the National Heart, Lung and Blood Institute of the National Institutes of Health ... Article: "Hip bone density predicts breast cancer risk... (EurekAlert!)

    Ten Most Medicated States  Jul 24, 2008
    In 2002, researchers halted a Women's Health Initiative trial, which examined the risks and benefits of continuous estrogen and progestin hormone-replacement therapy, after reporting that healthy, post-menopausal women taking the combination had an increased risk of breast cancer. In 2004, a trial involving the use of estrogen alone was stopped early because the therapy increased the risk of stroke. (Forbes)

    Abnormal sleep patterns in women linked to stroke  Jul 22, 2008
    The current investigation included 93,175 women, between 50 and 79 years of age, who were enrolled in the Women's Health Initiative study. Overall, 8. (Reuters)

    Obesity ups a woman's pancreatic cancer risk: study  Jul 18, 2008
    As part of a large study known as the Women's Health Initiative, Luo and colleagues followed more than 138,000 menopausal women in the United States for more than seven years to investigate the links between obesity and pancreatic cancer. Share. (Reuters India)

    Brigham and Women's Hospital Signs With LodgeNet Healthcare to Provide Patient Education and on Demand Entertainment Solutions  Jul 18, 2008
    BWH is also home to major landmark epidemiologic population studies, including the Nurses' and Physicians' Health Studies and the Women's Health Initiative. For more information about BWH, please visit. (Yahoo! Wire -- Entertainment News)

    Fat stomach raises pancreatic cancer risk  Jul 17, 2008
    As part of a large study known as the Women's Health Initiative, Luo and colleagues followed more than 138,000 menopausal women in the United States for more than seven years to investigate the links between obesity and pancreatic cancer. They found that 251 women developed the disease, and of these, 78 had the highest waist-to-hip ratios. (MSNBC -- Health)

    Do Antidepressants Make Bones Brittle?  Jul 15, 2008
    Spangler's team based its findings on a review of data from more than 93,000 women enrolled in the large Women's Health Initiative Observational Study. First, the researchers looked at antidepressant use, then they looked at the incidence of fractures. (MEDLINEplus)

    HRT use shows continual decline  Jun 20, 2008
    But further research, including the 2002 study from the Women's Health Initiative, demonstrated that women using either type of HRT may be at an increased risk for coronary heart disease and stroke. Since the publication of reports that HRT could bring more harm than benefit, many Canadian women have stopped using both types of HRT, CIHI said. (Globe and Mail)

    Estrogen therapy helps or hurts the brain depending on reproductive status  Jun 16, 2008
    Since the Women's Health Initiative study found that long-term therapy with estrogen or estrogen plus progestin may increase the risk of heart attack and stroke, many women have found it difficult to decide whether to take hormone therapy at menopause. Subsequently, several researchers have speculated that the timing of estrogen treatment may be important for estrogen's effects. (EurekAlert!)

    New KLRI Reports Shows Longevity Science Moving Beyond Studying the Obvious to the 'Downward Spiral' Paradigm in the Aging Process  Jun 11, 2008
    KLRI researchers have launched a national, multi-center study to evaluate the effects of estrogen therapy in women just before and after menopause to clarity some of the highly publicized but oversimplified research findings of the Women's Health Initiative (WHI). Researchers from KLRI have also launched a national study to evaluate the risks and benefits of testosterone therapy in older men. (PR Newswire)

    Cancer link to hormone therapy  Jun 2, 2008
    Millions of women around the world stopped using HRT after it was linked with increased breast cancer rates in the controversial Women's Health Initiative report in 2002, which last month was criticised as flawed at a World Congress in Madrid. However, two international studies published last year in The Lancet and New England Journal Of Medicine showed a strong link. (Sydney Morning Herald)

    Quest For Better Treatment For Effects Of Menopause  Jun 1, 2008
    (May 31, 2004) Despite the highly publicized closing of the Women's Health Initiative study, the scientific community should not rule out that women may benefit from hormone therapy after menopause, say. (Aug. (Science Daily)

    Breast cancer drops in 20-year first  Jun 1, 2008
    There was a worldwide scare in 2002 and millions of women stopped using HRT after a link was made between the therapy and increased breast cancer rates in the controversial Women's Health Initiative report in 2002. More recent research has suggested the link is greatly exaggerated. (Sydney Morning Herald)

    Long-term Hormone Replacement Therapy Increases Breast Cancer Risk Until 5 Years After Use, Study Finds  May 30, 2008
    Within five years after cessation of therapy the risk of breast cancer in former HRT users falls back to the level of women who never used HRT. "These results of the MARIE study confirm findings of two U.S. and U.K. studies (Women's Health Initiative Study and Million Women Study) that caused a stir in 2002 and 2003," says Professor Dr. Wilhelm Braendle of Hamburg-Eppendorf University Hospitals, who headed the study. "It has often been argued that the results of the U.S. study could not be... (Science Daily)

    High Blood Pressure Patients Advised To Use Home Monitors  May 27, 2008
    27, 2007) According to researchers studying postmenopausal women in the Women's Health Initiative, prehypertension exists in about 40 percent of postmenopausal women and it is associated with a 58 percent. (Oct. (Science Daily)

    Oral Hormone Replacement Therapy More Than Doubles Risk Of Blood Clots, Study Finds  May 27, 2008
    However, results from the Women's Health Initiative. . (Science Daily)

    Blood cholesterol levels predict risk of heart disease due to hormone therapy  May 24, 2008
    New analysis from the Women's Health Initiative. A new analysis of a subgroup of participants in the Womens Health Initiative (WHI) hormone therapy clinical trials suggests that healthy, postmenopausal women whose blood cholesterol levels are normal or lower are not at increased, short-term risk for heart attack when taking hormone therapy. (EurekAlert!)

    Hormone Replacement Therapy Is Safe For Healthy Women Entering Menopause, Summit Concludes  May 22, 2008
    Hormone replacement therapy (HRT) use declined after the Women's Health Initiative (WHI) study results were published in 2002 ... 4, 2007) Five years ago this summer the National Institutes of Health's stopped early a major portion of the Women's Health Initiative (WHI), a large and ambitious study to address the most common causes of ... 8, 2007) Secondary analyses of findings from the Women's Health Initiative suggest that women who begin hormone therapy within 10 years of menopause may have... (Science Daily)

    Cholesterol Test Spots When HRT Raises Heart Risks  May 22, 2008
    Some studies, notably earlier results from the U.S. government-sponsored Women's Health Initiative (WHI) have shown an increased risk of heart attacks and strokes among women who use hormone therapy. HRT also carries with it an increased risk of breast cancer. (Health-Finder)

    HRT: First Safe, Then Risky... Now Safe?  May 21, 2008
    In 2002, researchers cut short the Women's Health Initiative study of HRT, citing concerns over heart problems and strokes in women in the study who received the treatment. But while some supported the decision to halt the study, which led many women to stop their HRT regimens, many doctors felt the recommendations went too far, discouraging women they felt should be taking the treatment. (ABC News)

    'Hormone therapy safe for women'  May 21, 2008
    HRT use declined after the 2002 Women's Health Initiative (WHI) study which seemed to show that women taking HRT were at greater risk of breast cancer and heart disease. The study had a dramatic effect on public perceptions and confidence in the use of HRT.. (India Times, India -- Health/Science)

    Statins May Help Older Women Control Irregular Heartbeat  May 17, 2008
    The first study, by researchers at Northwestern University, involved 46,704 women participating in the Women's Health Initiative who completed questionnaires about their intake of omega-3 fatty acids. The second study looked at 38,933 healthy women over the age of 45 who had been randomly selected to receive either vitamin E or a placebo. (MEDLINEplus)

    When menopause turns up the heat  May 14, 2008
    At the heart of the question medically are multitudes of relatively short-term studies -- most notably a 2002 study by the Women's Health Initiative that blamed hormone therapy for an increased risk of heart disease and breast cancer and credited it with lowering the risk of colon cancer ... The Women's Health Initiative Study did women a great disservice,'' said Dr. Gregory Feldmeier, a Kalamazoo obstetrician/gynecologist who has examined the data from various hormone therapy studies and... (Kalamazoo Gazette, MI)

    Hormone Therapy: Does Timing Matter?  Apr 22, 2008
    8, 2007) Secondary analyses of findings from the Women's Health Initiative suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to ... 4, 2007) Five years ago this summer the National Institutes of Health's stopped early a major portion of the Women's Health Initiative (WHI), a large and ambitious study to address the most common causes of ... 26, 2007) Studies in female monkeys helped raise important questions about... (Science Daily)

    Cancer rates decrease for some groups  Apr 12, 2008
    In 2002, the Women's Health Initiative found that the long-term use of replacement therapy increased a woman's risk of breast cancer. Since the study's release, the use of the therapy has fallen substantially. (Los Angeles Times)

    Estrogen Therapy Increases Benign Breast Disease Risk, Study Suggests  Apr 10, 2008
    In the Women's Health Initiative study, 10,739 postmenopausal women with hysterectomy were assigned to either conjugated equine estrogen or a placebo ... D., of the Albert Einstein College of Medicine in New York and colleagues identified and examined non-cancerous breast biopsies in each of the Women's Health Initiative trial arms ... Although the women taking conjugated equine estrogen have not yet shown a significant increased risk of breast cancer in the Women's Health Initiative study, if... (Science Daily)

    Postmenopausal Women's Sexual Dissatisfaction Not Linked to Heart Troubles  Apr 10, 2008
    In this study, researchers from Boston University School of Medicine (BUSM) and Boston Medical Center (BMC) analyzed data collected from more than 93,000 sexually active postmenopausal women, aged 50 to 79, in the Women's Health Initiative Observational Study. The women, recruited at 40 clinical centers across the United States, were followed for eight to 12 years. (Health-Finder)

    Breast Lumps May Follow Estrogen Therapy  Apr 10, 2008
    The latest work, published in the Journal of the National Cancer Institute, re-examines data from the landmark Women's Health Initiative that found a variety of health risks from long-term hormone therapy. Only women who have undergone hysterectomies are able to use estrogen-only therapy, and the WHI originally included more than 10,000 of those women, who were given either estrogen or a dummy drug and tracked for about seven years. (Click2Houston, TX)

    Estrogen Therapy Linked to Benign Breast Disease  Apr 10, 2008
    The study involved 10,739 postmenopausal women who were assigned to receive estrogen or inactive "placebo" as part of the Women's Health Initiative CEE trial. Breast examinations and mammograms were performed at enrollment and then annually. (MEDLINEplus)

    Estrogen raises risk of benign breast disease  Apr 9, 2008
    They looked at 10,739 women past menopause who had taken part in a highly publicized study known as the Women's Health Initiative or WHI. The women in this part of the study had taken either estrogen alone or placebo and were followed for almost seven years. While the larger WHI study found that women who took combination hormone replacement therapy had a higher risk of heart attack, stroke, breast cancer and other serious conditions, this estrogen-only part of the study in women who had a... (Reuters)

    HRT Dosing May Determine Risks, Benefits  Apr 9, 2008
    A section of the original Women's Health Initiative (WHI), which was designed to look at health issues in postmenopausal women, was halted in 2002, when U.S. researchers found that hormone therapy led to an increased risk of adverse events that included heart attack, stroke, breast cancer and blood clots. The risk depended on whether the woman was taking estrogen alone or estrogen plus progestin, another female hormone. (MEDLINEplus)

    Walking Speed May Predict Stroke Risk  Apr 8, 2008
    The study, published in the medical journal Stroke, is based on data from the Women's Health Initiative (WHI), a major U.S. government study that began following more than 160,000 postmenopausal women ages 50 to 79 in the early 1990s. McGinn's team focused on 13,048 women who had no history of stroke when they entered the WHI. All of the women underwent a walking speed test that measured how long it took them to walk 6 meters, or roughly 20 feet. (MEDLINEplus)

    One Hormone Used In Hormone Replacement Therapy Linked To Breast Cancer, Study Shows  Apr 4, 2008
    The Women's Health Initiative estimated a 26 percent jump in the number of breast cancer cases among women ingesting estrogen and progestin. Hyder believes that a large number of these women might also have a p53 protein that is not active and, therefore, not able to inhibit MPA-induced growth factor that helps to proliferate the tumor cells. (Science Daily)

    Decreased Sexual Satisfaction Is Not Associated With Cardiovascular Disease In Postmenopausal Women  Mar 30, 2008
    Researchers examined data from the Women's Health Initiative Observational Study. Participants were sexually active postmenopausal women aged 50 to 79 years, recruited at 40 clinical centers throughout the United States and followed for 8-12 years. (Science Daily)

    Facing change  Mar 27, 2008
    Conventional hormone replacement therapy was the subject of a comprehensive, long-term federal study, and the results scared many women away: In a much-publicized 2002 report, called the Women's Health Initiative, scientists reported they stopped a long-term study of the drug Prempro because too many women were getting sick with breast cancer and heart disease. It was around this time when natural hormone therapy started gaining public support. (Waterloo-Cedar Falls Courier)

    Hormone Replacement Therapy Increases Breast Cancer Recurrence, New Study Finds  Mar 27, 2008
    In an accompanying editorial in the Journal of the National Cancer Institute, Kathy I. Pritchard, M.D., of the Sunnybrook Odette Cancer Center in Toronto discusses the results of the HABITS trial and the Women's Health Initiative trial (which showed increased breast cancer risk among healthy women) in the context of the much less worrisome findings from observational studies. Observational studies, she writes, can be misleading because they have inherent biases, such as the types of patients... (Science Daily)

    Medical Consent  Mar 21, 2008
    The 2002 results of the Women's Health Initiative study proved that HRT is life threatening to women. According to the Cancer Treatment Centers of America, factors that increase the amount of time that a woman s body is exposed to estrogen, such as hormone replacement therapy or birth control pills, increase the chances that she develops breast cancer. (Suite101.com)

    Reducing Heart Disease Risk Naturally Post-menopause  Mar 21, 2008
    8, 2007) Secondary analyses of findings from the Women's Health Initiative suggest that women who begin hormone therapy within 10 years of menopause may have less risk of coronary heart disease (CHD) due to. (Sep. (Science Daily)

    Cancer Risk Slightly Higher For Women In Discontinued Hormone Treatment Trial  Mar 8, 2008
    7, 2008) A follow up study of participants in the Women's Health Initiative (WHI) clinical trial led by a University of North Carolina at Chapel Hill researcher has found that women who were taking the combined hormone therapy of estrogen plus progestin may have an increased risk of cancer since the intervention was stopped, compared to participants in the trial's placebo group ... 8, 2007) Secondary analyses of findings from the Women's Health Initiative suggest that women who begin hormone... (Science Daily)

    Cancer risk for women after hormone treatments  Mar 6, 2008
    Women began taking the combination of hormones as part of the Women's Health Initiative, a 15-year research program began in 1991 sponsored by the U.S. Department of Health and Human Services, National Institutes of Health and the National Heart, Lung and Blood Institute. The effort was aimed addressing cardiovascular disease, cancer and osteoporosis in postmenopausal women. (Palo Alto Online, CA)

    Raised Breast Cancer Risk Persists after Combo Hormone Replacement Therapy Stopped  Mar 6, 2008
    Latest data from Women's Health Initiative points to continued need for mammograms ... The finding, published in the March 5 issue of the Journal of the American Medical Association, was based on data from the landmark Women's Health Initiative (WHI). (MEDLINEplus)

    Breast Cancer Risk Persists After Stopping Hormones  Mar 6, 2008
    The Women's Health Initiative study was halted prematurely in 2002 because of a 24 percent higher risk of breast cancer associated with the combination therapy of estrogen and progestin ... The overriding conclusion from the two Women's Health Initiative trials involving 27,347 post-menopausal women, aged 50 to 79, was that the overall risks of long-term use of hormone therapy outweighed the benefits. (Newsmax)

    Major US study finds cancer risk persists after hormone therapy  Mar 5, 2008
    "The question has been: Do the risks persist?" said Marcia Stefanick of Stanford University, who chairs the steering committee for the federally funded Women's Health Initiative ... But in 2002 researchers stunned doctors and women when they reported that the Women's Health Initiative had not only found that the hormones did not protect the heart but also actually increased the risk of heart attacks, strokes, blood clots, and breast cancer. (Boston Globe)

    Risks of hormone therapy decline over time, study finds  Mar 5, 2008
    An average of 29 months after going off hormones, women no longer have higher odds of getting heart disease, according to the latest analysis from the federally funded Women's Health Initiative ... That was the year researchers with the Women's Health Initiative dropped a bombshell: The huge research project, which was set up to see if giving hormones to healthy post-menopausal women could prevent heart disease, found that using the pills actually caused a few extra cases of heart disease and... (Chicago Tribune)

    Cancer risk lingers in menopausal women after hormone therapy  Mar 5, 2008
    A previous study by the Women's Health Initiative of U.S. found women taking ombination therapy of estrogen and progestin doubled their risk of blood clots, and raised their risks of stroke and heart attack ... The findings underscore the now-standard recommendation that women who take hormones to relieve hot flashes and other effects of menopause should use the lowest possible dose for the shortest time, said Marcia Stefanick of Stanford University, who chairs the steering committee for the... (Xinhuanet, China)

    Study: Post-menopause hormone pills linked to cancer  Mar 5, 2008
    Patients in the study, the Women's Health Initiative, took the hormone combination, sold under the brand name of Prempro, for an average of 5 years. Two or three years later, their risks of heart attacks, blood clots and strokes had returned to normal, according to the paper, published in today's) Journal of the American Medical Association. (USA Today)

    Hormone Therapy Risks Linger On  Mar 5, 2008
    Researchers with the Women's Health Initiative (WHI) are adding yet another chapter to the continuing (and confusing) story of hormone therapy (HT) taken during and after menopause. In the latest report, appearing in the Journal of the American Medical Association (JAMA), the study doctors report that the health risks of taking the combined hormones estrogen and progestin can linger for up to three years after women stop taking them. (Time.com)

    Hormones hurt screen's accuracy  Mar 3, 2008
    Researchers, led by Dr. Rowan Chlebowski from the Los Angeles Biomedical Institute at UCLA, looked at data pooled from the large Women's Health Initiative trial, which studied more than 16,000 women receiving either hormone therapy or a placebo pill. It has long been known that taking hormone replacement therapy increases a woman's chances of developing breast cancer, but the researchers found that the women taking hormone therapy were also more likely to have abnormal mammograms - even when... (Boston Globe)

    Hormone Replacement Therapy Appears To Have No Effect On Risk And Severity Of Rheumatoid Arthritis  Mar 2, 2008
    A new study using data from the Women's Health Initiative (WHI) clinical trials on hormone replacement therapy found that there were no significant differences in the risk of developing RA or the severity of RA between postmenopausal women who were on hormone replacement therapy and those who took placebos ... Article: "Effects of Postmenopausal Hormone Therapy on Rheumatoid Arthritis: The Women's Health Initiative Randomized Controlled Trials," Brian Walitt, Mary Pettinger, Arthur Weinstein,... (Science Daily)

    Hormone Therapy Increases Frequency Of Abnormal Mammograms, Breast Biopsies, Study Finds  Feb 28, 2008
    D., of the Los Angeles Biomedical Research Institute at Harbor--UCLA Medical Center, and colleagues studied 16,608 post-menopausal women who participated in the Women's Health Initiative (WHI) clinical trial, beginning in 1993 through 1998 ... 14, 2006) Estrogen-alone hormone therapy does not increase the risk of breast cancer in postmenopausal women, according to an updated analysis of the breast cancer findings of the Women's Health Initiative. (Science Daily)

    Study: Hormone therapy impedes cancer tests  Feb 27, 2008
    The study was part of the Women's Health Initiative, a huge study of post-menopausal women that was halted in 2002 when women on hormone therapy showed an increased risk of heart disease, stroke and breast cancer. The heart disease risk was later found to be negligible in younger women who start treatment at the onset of menopause, and the risks of stroke and breast cancer are minimal, researchers said. (San Francisco Chronicle -- Sports)

    Hormone Therapy Hinders Breast Cancer Detection  Feb 27, 2008
    NEW YORK (Reuters Health) - Detecting breast cancer with mammography and biopsy is more difficult in women who use estrogen and progestin hormone therapy, according to an analysis of data from the Women's Health Initiative (WHI) trial. Doctors "should be aware that breast cancer diagnosis is more difficult in women using combined hormone therapy," lead researcher Dr. Rowan T. Chlebowski told Reuters Health. (MEDLINEplus)

    Half A Million Cancer Deaths Have Been Averted Since Death Rate Drop, Report Shows  Feb 21, 2008
    The decreases may reflect the saturation of mammography utilization and reduction in hormone replacement therapy use that followed the publication of study results from the Women's Health Initiative in 2002. Among males under age 40 years, leukemia is the most common fatal cancer, while lung cancer predominates in men aged 40 years and older. (Science Daily)

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