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    News and Articles on White blood cell

    Archives: White blood cell

    FDA Approves Promacta(R) (Eltrombopag), the First Oral Medication to Increase Platelet Production for People With Serious Blood Disorder  Nov 21, 2008
    Prior to the initiation of PROMACTA, examine the peripheral blood differential to establish the extent of red and white blood cell abnormalities. Obtain CBCs, including platelet counts and peripheral blood smears, weekly during the dose adjustment phase of therapy with PROMACTA and then monthly following establishment of a stable dose of PROMACTA. Obtain CBCs, including platelet counts, weekly for at least 4 weeks following discontinuation of PROMACTA. Liver tests:Monitor serum liver tests (ALT,... (PR Newswire)

    • Residents go bald to support ailing fire chief  Nov 21, 2008
    Times-News: Magicvalley. to register or to login to your account. (Burley South Idaho Press, ID)

    Researcher tricks immune system in diabetic mice  Nov 21, 2008
    In the study, researchers took a type of white blood cell from the islet donor's spleen, called splenocytes, and treated them with a chemical that masked the cells' identity. They then injected these chemically treated cells into diabetic mice before and after the mice underwent islet cell transplantation. (EurekAlert!)

    Alexion swings to 3Q profit on Soliris sales  Nov 19, 2008
    Preserve your white blood cell count now. The National Heart, Lung and Blood Institute is actively seeking patients diagnosed with PNH to receive free treatment as part of clinical research studies. (Yahoo News -- Pharmaceutical Industry News)

    'Assasin cells' to treat HIV  Nov 12, 2008
    The Guardian reports that assassin cell therapy could be used to treat people with HIV, using specially enhanced white blood cells to target the virus. The technology takes advantage of the ability of certain peoples immune systems to keep up with the mutations of the virus, with researchers enhancing the ability of certain white blood cells, called T-cells, to recognise and attack cells infected with HIV. ... This was a study concerned with the use of modified killerT-cells - a... (NHS Choices)

    How Tuberculosis Might Be Thwarting Immune System: Proteomics Study Yields Clues  Nov 7, 2008
    In a collaboration between the research groups of Carolyn Bertozzi, director of Berkeley Lab s Molecular Foundry nanoscience center, and Jay Keasling, director of Berkeley Lab s Physical Biosciences Division, profiles were obtained for 546 different types of proteins in the membrane of a phagosome, an organelle of macrophages (a type of white blood cell) that essentially eats and destroys invading organisms (a process called phagocytosis) ... Phagocytosis is the process by which a macrophage... (Science Daily)

    Cancer patient's genome decoded  Nov 6, 2008
    WASHINGTON - Scientists for the first time have decoded the entire genome of a cancer patient, identifying a series of genes never before linked to the type of white blood cell cancer that ultimately killed the woman. The study, published yesterday in the journal Nature, represents a new approach to grasp the genetic underpinning of cancer and pave the way for better treatments, researchers at Washington University School of Medicine in St. Louis said. (Boston Globe)

    ‘Natural Killer’ Immune Cells Reveal Factors For Reproductive Success  Nov 6, 2008
    Natural Killer (NK) cells, a type of white blood cell, defend us from tumours, viruses and other potential dangers. They sense their environment through a repertoire of surface proteins (receptors), which detect other immune molecules, those belonging to the Major Histocompatability Complex (MHC). (Science Daily)

    Scientists decode first genome of cancer patient  Nov 6, 2008
    BEIJING, Nov. 6 (Xinhuanet) -- Scientists in U.S. for the first time have decoded the entire genome of a patient suffering from white blood cell cancer and found a set of mutations that may have caused the disease or aided its progression, according to media reports Thursday. They compared the tumor tissue of a woman who died of acute myeloid leukemia (AML) to her normal tissue, and sequenced 10 mutated genes in the cancerous tissue apparently involved in triggering the disease. (Xinhuanet, China)

    Researchers describe how chronic inflammation can lead to stomach cancer  Nov 6, 2008
    "We show in this study that IL-1 works by activating a type of white blood cell known as myeloid derived suppressor cells (MDSCs), which in our study appeared to be strongly pro-inflammatory. Blocking IL-1 or the myeloid (MDSCs) cells may represent a potential strategy to prevent stomach cancer.". Previous research has shown that stomach cancer is strongly linked to chronic inflammation, and that infection with H. pylori may trigger the chronic inflammation that can lead to malignancy, but it... (EurekAlert!)

    Ayurveda to cure chemotherapy effects  Nov 3, 2008
    Bhupinder Singh, a doctor working at the company's laboratory in Pune, said: "As a medical practitioner, I found the substance much helpful. Besides, there are other benefits like maintaining the white blood cell count and increase in the weight of patients.". Singh said the medicine available in powder form needs to be taken every morning by boiling it in water. (India Times, India)

    Study: AIDS treatment should begin earlier  Oct 27, 2008
    Current guidelines say that patients should begin treatment only when their levels of a type of white blood cell called CD4 T-cells fall below 350 per cubic millimeter. The AIDS virus targets these cells, which in healthy people throttle up the immune response. (USA Today)

    Lexicon Presents Phase 1 Clinical Trial Results for LX2931 At American College of Rheumatology Annual Meeting  Oct 26, 2008
    Lymphocytes are a type of white blood cell that play an important role in the immune system. Inappropriate activation of lymphocytes is often associated with autoimmune diseases, a spectrum of disorders in which the immune system malfunctions and causes the body to attack its own organs, tissues and cells. (Primezone Releases)

    Mercury Pollution Causes Immune Damage To Harbor Seals  Oct 25, 2008
    By applying increasing doses of MeHg to lymphocytes, a type of white blood cell, the authors determined that the amount of mercury found in the blood of the seals studied was enough to cause damage to the important immune system cells. They said, "Although the in vitro approach utilised in this investigation represents an extreme reductionism relative to the complex situation in the intact organism, it provides an insight into the specific effects of mercury pollution.". (Science Daily)

    Silencing A Protein Could Kill T-Cells, Reverse Leukemia  Oct 24, 2008
    For a short time, the immune system also produces large numbers of a type of white blood cell, cytotoxic T-cell that kills other infected cells. Once the pathogens are eliminated, these killer T-cells quickly die on their own, save for a few that remain in case the same infection returns. (Science Daily)

    Drug may reverse MS brain damage  Oct 23, 2008
    Alemtuzumab works by destroying a type of white blood cell called a lymphocyte, which, in MS, plays a key role in causing the damage associated with the disease. Effectively, this shuts down the immune system, allowing it to re-boot without the original fault. (BBC News)

    New hope for multiple sclerosis sufferers  Oct 23, 2008
    Alemtuzumab works by destroying one population of white blood cell (lymphocytes) and, by shutting down the immune system, inhibits the damage to brain tissue that occurs in MS.. "The ability of an MS drug to promote brain repair is unprecedented. We are witnessing a drug which, if given early enough, might effectively stop the advancement of the disease and also restore lost function by promoting repair of the damaged brain tissue," says Dr Alasdair Coles, University Lecturer at the Department... (EurekAlert!)

    Obesity 'lifts inflammation risk'  Oct 18, 2008
    A US team found levels of white blood cells were highest in men who were unfit and overweight. White blood cells are key to fighting infection, but high levels can be a sign of inflammation, which is linked to coronary heart disease ... Blood tests were taken, and analysed for their content of various types of white blood cell. (BBC News)

    Cox Plate plans for major cup contenders  Oct 17, 2008
    "Results of tests revealed the white blood cell count had improved," RV chief steward Terry Bailey said yesterday. "We will take another one as a precaution but I do believe the horse is on track.". (Sydney Morning Herald -- Sport)

    Foods that Boost Immunity  Oct 15, 2008
    Vitamin A has been shown to enhance white blood cell functioning which helps the body resist and fight off infection ... Not only does vitamin C increase production of white blood cells to help the body fight off infection, vitamin C also increases the body's level of interferon, which prevents viruses from even entering the body ... Zinc is a mineral that not only increases the production of white blood cells, but also increases what are known as T-cells, which also help the body fight... (Suite101.com)

    Time Of Day Influences Yield For Pharmacologically Stimulated Stem Cell Mobilization  Oct 15, 2008
    In mice, the cells that give rise to mature blood cells, called hematopoietic stem cells (HSC), are regulated under the influence of rhythmic circadian signals that influence expression of Cxcl12, a gene involved in white blood cell migration. "Previous research has shown that the "sympathetic" branch of the nervous system, which is involved in stress responses, tightly regulates the amount of Cxcl12 expressed in the bone marrow by circadian oscillation of noradrenaline release. Blood stem cell... (Science Daily)

    Virus Review  Oct 13, 2008
    You must build an army of white blood cells to contain and fight back against these bad bugs. To release a white blood cell, you simply touch the screen ... As more of the screen is covered with white blood cells, a gauge in the upper corner of the screen fills. (IGN Wireless Games)

    Statins may prevent miscarriages  Oct 11, 2008
    These antibodies activate a protein, C5a, that activates another protein, tissue factor, that is expressed on the surface of certain white blood cells called neutrophils ... To find out, Dr. Girardi and colleagues examined the white blood cells from mice that had APS and discovered that these cells expressed certain receptors called PAR2 (protease-activated receptor 2) ... Stimulating this receptor led to the activation of white blood cells that attacked the placenta and hurt the fetus. (EurekAlert!)

    NIH scientists discover crucial control in long-lasting immunity  Oct 11, 2008
    National Institutes of Health (NIH) scientists have identified a protein that plays matchmaker between two key types of white blood cells, T and B cells, enabling them to interact in a way that is crucial to establishing long-lasting immunity after an infection ... Using a special microscopy technique that allows direct visualization of immune cell actions in living mice, they observed how T and B cells and another type of white blood cell, the dendritic cell, interact dynamically within mouse... (EurekAlert!)

    Modestan not slowing down on softball fields  Oct 8, 2008
    Partin said he felt no symptoms of the disease, and medication has helped him regulate his white blood cell count. Doctors credited his activity to Partin's good health. (Modesto Bee, CA)

    The faith to survive  Oct 5, 2008
    Shelly Cato and some others who are further along in their treatment commiserate about an injection, called Neulast, that is meant to boost their white blood cell count. "It hit my knees and my hips and my joints. It's really bad," Mrs. Cato said. (The Augusta Chronicle)

    Cancer chronicles  Oct 3, 2008
    It results when a lymphocyte (type of white blood cell) undergoes a malignant change and begins to grow uncontrollably. These cells eventually crowd out healthy ones and create tumors that enlarge the lymph nodes. (North County Times)

    Strong association found between prevalence of low white blood count and women of African descent  Sep 20, 2008
    "The goal of our study was to learn as much as we could about the association between a single nucleotide polymorphism (SNP), which creates a person's unique DNA sequence, and low white blood cell counts (WBC)," said Victor, R. Grann, MD, professor of Epidemiology and Health Policy and Management at Columbia University Mailman School of Public Health, professor of Medicine at the Columbia University College of Physicians ons, director of Research Recruitment and Minority Outreach of the Herbert... (EurekAlert!)

    Stanford researchers find leukemia clue  Sep 19, 2008
    The molecular signal, called GSK3, has been found to enable a white blood cell cancer which accounts for five to 10 percent of child and adult leukemia cases. "GSK3 has never been implicated in promoting cancer," Cleary, a professor of pathology and pediatrics, said. (Palo Alto Online, CA)

    New Leukemia Signal Could Point Way To Better Treatment  Sep 19, 2008
    But new data show that GSK3 fuels a deadly form of white blood cell cancer, which accounts for five to 10 percent of child and adult leukemias and more than three-quarters of leukemias diagnosed in infants ... Most leukemias begin in just one of the body's two white blood cell factories, either the lymph nodes or the bone marrow ... Thus, it's possible that giving GSK3 inhibitors will have a double-whammy effect on leukemia, killing the cancerous white blood cells and promoting growth of healthy... (Science Daily)

    Registration statement including financial report  Sep 16, 2008
    Topical imiquimod activates the body's immune system, causing the migration of white blood cells to the treated area to attack and kill the damaged skin cells ... Second, PEP005 activates the body's immune system, causing neutrophils, a type of white blood cell, to infiltrate the treated site ... The white blood cells activated as a result of PEP005 treatment appear to target and destroy any residual tumor cells, which appears to limit or prevent relapse of tumors. (Sydney Morning Herald)

    Semen Analysis  Sep 14, 2008
    White blood cell count - there has to be a certain number of white blood cells within the semen sample ... White blood cell count - less than one million per sample is considered normal. (Suite101.com)

    The Pitfalls of Linking Doctors' Pay to Performance  Sep 10, 2008
    His white blood cell count was normal, and he wasn t coughing up sputum ... His white blood cell count almost tripled. (Atlanta Journal-Constitution -- Health)

    Innate immune system targets asthma-linked fungus for destruction  Sep 3, 2008
    Researchers at Mayo Clinic and the Virginia Bioinformatics Institute (VBI) have revealed that eosinophils, a particular type of white blood cell, exert a strong immune response against the environmental fungus Alternaria alternata ... Principal Investigator Hirohito Kita, M.D., from Mayo Clinic, remarked: "Our results strongly demonstrate that eosinophils have the capacity to recognize and exert immunological responses to certain fungi such as Alternaria. We have shown that CD11b receptors on... (EurekAlert!)

    Women may not realize worst chemotherapy effects  Sep 2, 2008
    Other serious side effects included low white blood cell or platelet count, and dehydration or electrolyte disorders. "Women should be aware that chemotherapy can cause side effects, but should not make a decision regarding whether or not to receive chemotherapy solely based on the results of our study," said lead author Dr. Michael Hassett, an instructor in medicine at Harvard Medical School and a medical oncologist at the Dana-Farber Cancer Institute in Boston. (Detroit Free Press)

    Chronic Stress Alters Our Genetic Immune Response  Aug 28, 2008
    They found that among the caregivers, even though they had normal cortisol levels in their blood, the pattern of gene expression in the monocytes, a type of white blood cell involved in the body's immune response, was altered so that they were relatively less responsive to the anti-inflammatory actions of cortisol, but relatively more responsive to pro-inflammatory actions of a transcription factor called nuclear factor-kappa B, or NF- B. ... D., corresponding author, explains more simply that,... (Science Daily)

    iReporters share worst vacation nightmares  Aug 19, 2008
    "My doctor was looking at the report all confused, and he said of course your white blood cell count was up -- that's what happens when you get sick!" Bush said. Bush's parents didn't tell him about the cancer diagnosis until the family had returned home and his own doctor had refuted it. (CNN -- Travel)

    Ashwagandha, milk boost immunity!  Aug 17, 2008
    Lymphocytes are a type of white blood cell and come in four forms: (1) Natural Killer cells, which are a major component of the immune system and best known for their ability to respond to virally-infected cells and tumors; (2) B-cells, which make antibodies that bind to a virus or microorganism and then destroy it; (3) CD4+ T cells (also known as helper cells), which coordinate the immune systems response; and (4) CD8+ T cells, which kill cells that become infected ... Consuming Ashwagandha... (India Times, India)

    Biotech Campaigns for Easier Access to Generic Drug Market  Aug 14, 2008
    Last month, Insmed demonstrated that its version of Neupogen, which stimulates white blood cell growth, was equivalent in 32 healthy volunteers to the original product from. But, for Insmed's version, there is no pathway for approval. (Washington Post -- Technology)

    White blood cell uses DNA 'catapult' to fight infection  Aug 14, 2008
    SALT LAKE CITY U.S. and Swiss scientists have made a breakthrough in understanding how a type of white blood cell called the eosinophil may help the body to fight bacterial infections in the digestive tract, according to research published online this week in Nature Medicine ... Eosiniphils, which comprise only 1 to 3 percent of human white blood cells, are known to be useful in the body's defense mechanisms against parasites ... Unlike other white blood cells, which are distributed throughout... (EurekAlert!)

    Living with breast cancer: Register editor begins trek to recovery with positive attitude  Aug 10, 2008
    My white blood cell counts are down, also a typical chemo reaction, and now I have to take an antibiotic and be careful not to catch a cold. Sitting in the doctor s office, I am staggered by the number of people who also visit. (New Haven Register, CT)

    Hope for end to rejection drugs  Aug 7, 2008
    The complex procedure involves mixing the patient's infection-fighting white blood cells with cells from the donor ... The TAICs are created by isolating a type of white blood cell from the donor, and modifying them chemically in the lab. (BBC News)

    The sea creature giving Britain's olympic sailing squad a boost  Aug 6, 2008
    High concentrations of these are normally released by white blood cells as a counter-measure against infection, and as such, they can be present even if no symptoms have yet been felt ... " Fatigue test She said that full clinical trials of the technology were planned, and said that the test could even reveal, with some confidence, athletes with abnormal white blood cell activity due to overtraining. She said: "We are becoming more and more confident in the accuracy of the results ... " Knight... (BBC News -- Health)

    New Cancer Vaccine being Tested  Aug 1, 2008
    Its then mixed with a type of white blood cell taken from a patient through a process called leukapheresis. Cells are then developed in an outside lab and combined with the tissue taken initially taken during surgery. (WOKR13 Rochester)

    Proton Channels Inhibit Release Of Histamine During Allergic Reactions, Novel Study Finds  Aug 1, 2008
    ScienceDaily (July 31, 2008) Inhibiting the proton currents in basophils, a rare type of white blood cell, can stop the release of histamine and could provide a new target for allergy and asthma drugs according to a new study by researchers at Rush University Medical Center in Chicago and the Johns Hopkins Asthma and Allergy Center in Baltimore ... When allergens enter the body, they can be recognized by IgE antibodies bound to basophils, causing these white blood cells to release the... (Science Daily)

    'Biomarkers' May Help Spot, Track Alzheimer's  Jul 31, 2008
    One study being presented at the International Conference on Alzheimer's Disease (ICAD) in Chicago found that differences in levels of CD-69, a protein involved in white blood cell growth and production, allowed researchers to distinguish between people with Alzheimer's, people with Parkinson's-related dementia and those who were cognitively normal. The study, from researchers at the University of Leipzig in Germany, was based on a theory that Alzheimer's occurs when neurons get a false signal... (MEDLINEplus)

    Markers in Blood and Spinal Fluid, and a New Imaging Agent, Show Promise for Early Detection of Alzheimer's  Jul 30, 2008
    "It is greatly preferable that these markers be easy to obtain, such as in samples of blood or urine, or through readily available imaging technologies, such as MRI and PET." Blood Test on White Blood Cells May Be Useful for Early Detection of Alzheimer's Healthy brain cells do not go through the process of division and replication (known as the "cell cycle") that is common in other cells in the body ... Lymphocytes are white blood cells in the immune system that can easily be collected for... (PR Newswire)

    Men's Health Matters  Jul 29, 2008
    The basic blood tests, which should be taken after the man has been fasting for about 12 hours, should measure glucose (blood sugar), lipids (cholesterol), red and white blood cell counts, blood chemistry and liver function. These constitute the essential minimum although other examinations and investigations may be indicated depending on the individual. (Suite101.com)

    Identification of protein able to stimulate production of T-cells  Jul 23, 2008
    A team of Canadian and Finnish scientists has identified a protein able to stimulate the production of T-cells, the white blood cells involved in the recognition and the elimination of infectious agents ... Wnt4 protein stimulates white blood cells ... By inducing an overproduction of the Wnt4 protein in the cells of the mouse immune system, Dr. Perreault and his collaborators were able to observe the stimulatory effect this protein exerts on the development of white blood cells. (EurekAlert!)

    Noah Holmes, who was diagnosed with Stage 4 Teratoma at 10 months old, celebrated his first birthday July 11 during his third chemotherapy treatment at Oklahoma City. Shown is Rebekah Holmes handing Noah his birthday cake.  Jul 20, 2008
    It [white blood cell count] was above 2,000, which doctors said was good, Rebekah said. Also, she said Noahs doctors were really pleased with how much the tumor has decreased in size. (Durant Daily Democrat, OK)

    Cancer Metastasis: Cellular Decisions Predicted With Computer Program  Jul 17, 2008
    (May 1, 2008) Metastasis, the spread of cancer throughout the body, can be explained by the fusion of a cancer cell with a white blood cell in the original tumor, according to Yale School of Medicine researchers. (Sep. (Science Daily)

    Insmed copies Amgens Neupogen but FDA likely to wait for biogeneric pathway before approving the drug  Jul 15, 2008
    Nevertheless, the Virginia-based company is pressing on in developing biogeneric versions of Amgens blockbuster G-CSF drugs Neupogen and Neulasta, which treat a low white blood cell condition called neutropenia. The company today announced that tests have shown that its INS-19 product is bioequivalent to reference product Neupogen. (FT.com -- Markets)

    Tumor-inhibiting protein could be effective in treating leukemia  Jul 15, 2008
    Tuszynski said leukemia cells arise from monocytes, a specific white blood cell that is a part of the human body's immune system that protects against bloodborne pathogens and moves quickly to sites of infection. As monocytes enter tissue, they undergo a series of changes to become macrophages. (EurekAlert!)

    Should Children Take Statins  Jul 13, 2008
    Suboptimal white blood cell activity (white cells are major components of our immune system, and they re necessary to help protect us from infections and notably cancer). Reduced strength of muscle fiber contraction. (Suite101.com)

    PTSD Causes Early Death From Heart Disease, Study Suggests  Jul 8, 2008
    15, 2008) Post-traumatic stress disorder is an indicator of long-term health problems, similar to biological warning signs such as elevated white blood cell counts. With an in-depth study of Vietnam vets. (Science Daily)

    Summary Judgment Granted for SEROQUEL(R) Patent Litigation  Jul 2, 2008
    Leukopenia, neutropenia, and agranulocytosis (including fatal cases), have been reported temporally related to atypical antipsychotics, including SEROQUEL. Patients with a pre-existing low white blood cell (WBC) count or a history of drug induced leukopenia/neutropenia should have their complete blood count monitored frequently during the first few months of therapy. In these patients, SEROQUEL should be discontinued at the first sign of a decline in WBC absent other causative factors. (PR Newswire)

    How has cancer affected your life?  Jun 30, 2008
    Yeah) and now they give you shots to stimulate white blood cell production (at least in my case) that cause relentless, incapacitating pain that made you simply want to give up on living just to make it stop. Ok, I said it, chemotherapy sucks and I am really good at being tough and not letting everyone know all the s***ty stuff thats happening to me at once, but you know it sucks. (Columbus Telegram, NE)

    Clinical Trials Begin This Week on New Cancer Therapy That Cured ...  Jun 29, 2008
    The therapy involves the transfusion of white blood cells from cancer-resistant donors into cancer patients, letting loose a uniquely qualified army of disease fighters to attack the invading tumor ... The solution is apparently hidden in the mice's white blood cells, which are like a tiny biological army ... For some reason _ Cui and his team don't know why _ the white blood cells from the immune mice could defeat the cancer every time, whereas the other mice's white blood cells were unable to... (RedOrbit)

    DeGowin's famed Strauss to leave UI next week  Jun 27, 2008
    It was not until coming to Iowa in 1976 and receiving a grant to study granulocytes - a type of white blood cell - that he switched his research focus. Granulocyte therapy is not the only transfusion component he has helped define. (Daily Iowan, IA)

    The tiniest things  Jun 27, 2008
    On the other hand, a platelet or white blood cell contains only two to six mitochondria. And a red blood cell, which has no nucleus, has no mitochondria, though mitochondria are critical to its construction. (San Diego Union-Tribune)

    Potential New Way To Block Inflammation In Autoimmune Disease Discovered  Jun 25, 2008
    While closely related to TNFR1, DR3 is expressed in T cells, a different kind of immune cell (a white blood cell that identifies and fights infection) than those that express TNFR1, Dr. Siegel said. The NIAMS group collaborated with a laboratory in Cardiff, Wales, which had generated genetically engineered mice deficient in DR3, as well as with a research group at the NIH's National Institute of Allergy and Infectious Diseases (NIAID), which has developed mouse models of disease with strong T... (Science Daily)

    Cancer beaten by dose of own cells  Jun 20, 2008
    American researchers led by Cassian Yee of the Fred Hutchinson Cancer Research Centre collected a type of white blood cell, known as CD4 T-cells, from the patient and separated those that targeted the melanoma cells. These were grown in the laboratory and more than 5 billion were injected into the man, stimulating other T-cells, known as CD8, to fight the tumours. (Sydney Morning Herald -- Australia)

    Patient's Own Infection-Fighting T Cells Put Late-Stage Melanoma Into Long-Term Remission - Without Chemotherapy or Radiation  Jun 19, 2008
    Yee and colleagues removed CD4+ T cells, a type of white blood cell, from a 52-year-old man whose Stage 4 melanoma had spread to a groin lymph node and to a lung. T cells specific to targeting the melanoma were then expanded vastly in the laboratory using modifications to existing methods. (PR Newswire)

    HOPE FOR SKIN CANCER CURE...  Jun 19, 2008
    Yee and his associates from the Clinical Research Division at Fred Hutchinson Cancer Research Center in Seattle removed CD4+ T-cells, a type of white blood cell, from a 52-year-old man whose melanoma had spread to a groin lymph node and to one of his lungs. The melanoma was already well advanced and in stage four. (The Drudge Report)

    Patient, Heal Thyself: Body's Own Immune Cells Whack Late-Stage Tumor  Jun 19, 2008
    Lead study author Cassian Yee, an immunologist, says that he and his team removed so-called (a type of infection-fighting white blood cell) from a 52-year-old man with stage IV (the most advanced) the deadliest form of skin cancer; it had spread to a lung and a groin lymph node. The researchers grew T cells (that target a specific protein, or antigen, on the tumor cells) in the lab until they had a population they believed was large enough to destroy the cancer. (Scientific American)

    Is Radiation Good For You?  Jun 19, 2008
    A news release said that radiation can increase white blood cell counts and improve the function of blood. He said that radioactive waste could be used to provide radiation treatment for people who need it. (KFOXTV.com, TX)

    Ancient Antibody Molecule Offers Clues To How Humans Evolved Allergies  Jun 15, 2008
    Lead researcher, Dr. Rosy Calvert said: "Although these antibodies all started from a common ancestor, for some reason humans have ended up with two rather specialised antibodies, whereas chickens only have one that has a much more general function. "We know that part of the problem with IgE in humans is that it binds extremely tightly to white blood cells causing an over-reaction of the immune system and so we wanted to find out whether IgY does the same thing. " By examining how tightly IgY... (Science Daily)

    Fungal exposure and gardening  Jun 14, 2008
    Other features at presentation included high fever, high breathing rate, irregular chest X-rays, high white blood cell count and crackling sounds in the lung while breathing. The initial assumption was that he had pneumonia, so he was put on antibiotics while further investigations took place. (NHS Choices)

    TB Treatment For Elderly Likely Requires Boost To Immune Response  Jun 13, 2008
    Mathematical modeling of how mice respond to TB infection suggests that potential therapy options for elderly TB patients could either increase their white blood cell count or enhance infected cells interaction with their immune system. Simulations of TB infection in an old mouse showed that increasing the number of infection-fighting white blood cells, called CD4 T cells, could be particularly effective at bolstering the mouse s immune response, which naturally slows with aging. (Science Daily)

    Family thinks tainted tomatoes contributed to man's death  Jun 7, 2008
    His family told 11 News that recent tests showed he had an improved white blood cell count, which is key in the battle against lymphoma. After the dinner, Rivera and other family members became ill. (KHOU.com, TX)

    Clinical study shows biological and clinical activity in relapsed leukemia patients  Jun 5, 2008
    CLL is characterized by proliferation of malignant white blood cells, referred to as lymphocytes, in the bone marrow, lymph nodes and spleen, which leads to an increase in white blood cell counts as well as enlarged lymph nodes and spleens in most patients. The disease is progressive and often fatal with a five year survival rate of 75. (EurekAlert!)

    New Approach To Treating Autoimmune Disease Developed  Jun 4, 2008
    9, 2007) Multiple sclerosis, diabetes, and arthritis are among a variety of autoimmune diseases that are aggravated when one type of white blood cell, called the immune regulatory cell, malfunctions. In. (Science Daily)

    Anemia Drugs May Speed Tumor Growth in Some Cancer Patients  Jun 3, 2008
    In particular, patients taking drugs that interfered with protein binding such as Norvasc for high blood pressure, Prilosec for heartburn, and the pain reliever Celebrex were more likely to experience hematologic side effects such as low white blood cell counts. Patients taking drugs that act on a group of enzymes known as cytochrome p450 were more likely to experience effects such as fatigue or diarrhea. (MEDLINEplus)

    Skin Defects Set Off Alarm With Widespread And Potentially Harmful Effects  Jun 2, 2008
    The research team found that the mice's irritated skin produced an alarm signal in the form of a natural inflammatory substance called TSLP (thymic stromal lymphopoietin), which launched a massive overproduction of white blood cells and ultimately killed the mice ... "I started looking for the cause, and one of the first things I noticed was the high white blood cell counts." ... High levels of TSLP activated an immune response that produced extreme numbers of B-cells, a kind of white blood cell... (Science Daily)

    NEW DATA FOR PAZOPANIB - GSK'S LATEST INVESTIGATIONAL ANTI-CANCER AGENT - SHOWS PROMISE ACROSS MULTIPLE CANCERS  Jun 1, 2008
    These toxicities included elevated liver enzymes (2), hypertension (1), shortness of breath (1), pneumonia (1), urinary tract infection (1), reduced white blood cell count (1) potassium increase (1) and rash (1). One Grade 4 toxicity of a pulmonary embolus was seen in a patient in relation to surgery, 18 days after finishing pazopanib treatment. (PR Newswire)

    Gum Disease Might Boost Cancer Risk  May 27, 2008
    Compared to men with healthy gums, men with a history of gum disease had a 36 percent increased risk of lung cancer, a 49 percent hike in risk of kidney cancer, a 54 percent higher risk of pancreatic cancer, and a 30 percent increased risk of white blood cell cancers. In addition, men who had fewer teeth at the beginning of the study had a 70 percent increased risk of developing lung cancer, compared with men who had 25 to 32 teeth, Michaud's team found. (Health-Finder)

    Kill it before it kills you  May 24, 2008
    Leukemia is a cancer that starts in the white blood cells (also called WBCs or leukocytes). Blood consists of several types of cells (white blood cells, red blood cells and platelets) carried in a fluid called plasma ... White blood cells help prevent and fight infection by destroying bacteria, viruses and other foreign cells. (Deccan Herald)

    How Stem Cells Decide What They'll Be  May 22, 2008
    Led by Sui Huang, MD, PhD, a Visiting Associate Professor in the Children's Hospital Boston Vascular Biology Program (now also on the faculty of the University of Calgary), and Hannah Chang, an MD/PhD student in Children's Vascular Biology Program, the researchers examined how blood stem cells "decide" to become white blood cell progenitors or red blood cell progenitors ... Conversely, when stem cells were exposed to granulocyte--macrophage colony-stimulating factor, which stimulates white blood... (Science Daily)

    Kennedy's tumor prognosis is weakened by age  May 21, 2008
    Black developed a technique to remove proteins from the tumor and attach them to a form of white blood cell called an antigen-presenting cell, which is then injected back into the patient to activate the immune system. In phase II studies of the vaccine, which are nearly complete, survival after two years increased from 8% to 42%, he said. (Los Angeles Times)

    Patients with mystery diseases may get free care  May 20, 2008
    Yet under the microscope, her immune system seemed normal except for an unexplained low white blood cell count. In 1990, not long after that amputation, her desperate parents brought her to NIH, where the hospital director made us a promise, Young recalled. (MSNBC -- Health)

    Abnormal 'editing' of gene messages may be a cause of lupus  May 20, 2008
    WINSTON-SALEM, N.C. Researchers at Wake Forest University have uncovered evidence that the abnormal editing of gene messages in a type of white blood cell may be behind the development of lupus ... D., assistant professor of internal medicine and senior author, said that in systemic lupus erythematosus, the normal editing process goes awry, causing a shift in the balance of proteins that results in impaired functions in T cells, a type of white blood cell involved in the regulation of immune... (EurekAlert!)

    AIDS vaccine still out of reach  May 18, 2008
    Merck's vaccine aimed to stimulate T cells, a type of white blood cell key to the body's immune response, taking a different approach than numerous more traditional vaccines already tested without success. "The (research) community is depressed because we see no hopeful route to success," American biologist and Nobel prize laureate David Baltimore said of the quest for an AIDS vaccine, at the opening of the latest conference of the American Association for the Advancement of Science, in... (India Times, India -- Health/Science)

    Common Bacteria Activating Natural Killer T Cells May Cause Autoimmune Liver Disease  May 17, 2008
    The autoimmune process was mediated by T cells (a white blood cell important to immune response), but early disease onset required the participation of Natural Killer T cells after they selectively recognized glycosphingolipid antigens on the cell wall surface of Novosphingobium aromaticivorans. NKT cells are a unique group of T cells that share properties of both T cells and Natural Killer cells, which are naturally toxic to other cells and typically target tumor cells or cells infected with... (Science Daily)

    Eribulin Mesylate Demonstrated Anti-Tumor Activity in Heavily Pretreated Patients with Advanced Breast Cancer  May 16, 2008
    The most frequently reported Grade 3 (severe) or Grade 4 (disabling or life-threatening) adverse events were neutropenia (a decrease in the number of granular white blood cells, 54%); febrile neutropenia, 5. 5%, leukopenia (low white blood cell count, 14%), and weakness/fatigue (10%; no Grade 4 events). (PR Newswire)

    When the environment can kill you  May 10, 2008
    The virus targets a patient's immunity by destroying a critical protein, Stat 1, found in a type of white blood cell that is responsible for the production of interferon, research by three research groups found. Interferon helps fight viruses and bacterial infections. (Palo Alto Online, CA)

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