Hot Flashes, Night Sweats a Good Sign for Breast Cancer Patients Oct 31, 2008
5 percent of women who reported hot flashes and night sweats at the three-month follow-up visit had a lower breast cancer recurrence rate after nine years (18 percent) than women who didn't report new vasomotor symptoms (23 percent) ... "The appearance of new vasomotor symptoms or joint symptoms within the first three months is a useful biomarker, suggesting a greater response to endocrine treatment, compared with women without these symptoms," wrote Professor Jack Cuzick, Cancer Research U.K.... (MEDLINEplus)
Groundbreaking cancer studies to be unveiled at ASTRO annual meeting Sep 16, 2008
Acupuncture Reduces Side Effects of Breast Cancer Treatment As Much As Conventional Drug Therapy Acupuncture is as effective and longer-lasting in managing the common debilitating side effects of hot flashes, night sweats, and excessive sweating (vasomotor symptoms) associated with breast cancer treatment and has no treatment side effects compared to conventional drug therapy, according to a first-of-its-kind study presented September 24, 2008, (embargo lifts Tuesday, September 23, 2008, at 9... (EurekAlert!)
HRT Improves Quality Of Life For Some Aug 24, 2008
argues that for older women, health related quality of lifecan be improved by hormone replacementtherapy (HRT) (Medical News Today)
Effects of HRT on sleep and sex Aug 23, 2008
"Combined HRT might improve some aspects of health related quality of life in the late menopausal phase in women with and without classic vasomotor menopausal symptoms." ... The areas of questioning include: depressed mood, physical symptoms, memory and concentration, vasomotor symptoms, anxiety or fears, sexual functioning, sleep problems and menstrual symptoms ... These improvements were in the areas of vasomotor symptoms such as flushing, sexual functioning and sleep problems. (NHS Choices)
KV Pharmaceutical Company Reports Fiscal 2009 First Quarter Results Aug 12, 2008
Evamist(TM) Having received approval for Evamist(TM) from the FDA in July 2007, the Company has had a successful launch of this patented estradiol transdermal spray that offers a novel approach to the treatment of moderate-to-severe vasomotor symptoms due to menopause ... Furthermore, Dr. Buster and his co-authors provided insight into why Evamist(TM) is an exciting option for women experiencing moderate-to-severe vasomotor symptoms associated with menopause, particularly with regard to focusing... (PR Newswire)
Sleep Problems Associated With Menopause Vary Among Ethnic Groups Jul 4, 2008
They were also asked about the frequency of vasomotor systems such as hot flashes, cold sweats, and night sweats ... However, whether or not women were hormone users did not influence the effect of vasomotor systems or changing hormone levels on sleep symptoms ... Women who reported vasomotor symptoms on more days in the preceding two weeks also were more likely to report difficulty sleeping. (Science Daily)
Hot Flashes Under-reported, And Linked To Forgetfulness Jun 18, 2008
A number of studies have looked at the relationship between menopausal symptoms (vasomotor symptoms, hot flashes and sleep disturbances that accompany hot flashes) and memory complaints and found no relationship between subjective, or self-reported, hot flashes and objective performance on memory tests in women ... The study suggests that if women are treated for their vasomotor symptoms it may improve memory function in women with hot flashes, said Maki. (Science Daily)
Bionovo Reports First Quarter 2008 Financial Results May 10, 2008
-- The Company commissioned and reported results from two independent physician surveys which showed the Company's drug candidate MF101 could become first-line treatment for menopausal vasomotor symptoms (hot flashes). In both qualitative and quantitative studies, 124 board certified physicians in internal medicine or obstetrics and gynecology specializing in the treatment of menopause reported that MF101, if approved, would be their drug of choice for the treatment of hot flashes. (PR Newswire)
Too much love Apr 11, 2008
You may have vasomotor rhinitis. The condition is a kind of catch-all medical phrase that means, roughly, Youve got something screwy with your nose and we dont think its an allergy. (MSNBC -- Health)
Hormonal Contraception in Women of Older Reproductive Age Mar 20, 2008
Please for full text and personal services. Volume 358:1262-1270. (New England Journal of Medicine)
FDA Approves PRISTIQ(TM) for the Treatment of Adult Patients with Major Depressive Disorder Mar 1, 2008
In particular, there can be no assurance that PRISTIQ will be commercially successful in the highly competitive market for antidepressants in the United States, or that PRISTIQ will be approved in the future for other indications (including treatment of vasomotor symptoms associated with menopause) and/or in other countries. Other risks and uncertainties include the inherent uncertainty of the timing and success of, and expense associated with, research, development, regulatory approval and... (PR Newswire)
KV Pharmaceutical Reports Record Revenues for Fiscal 2008 Third Quarter and Year-to-Date on a Preliminary Basis Feb 28, 2008
5 million (net of tax) of in-process research and development costs related to the previously reported acquisition of Evamist(TM), a transdermal estradiol spray for the treatment of vasomotor symptoms associated with menopause. Excluding this write-off, earnings (non-GAAP) for the nine-month period would have been $86. (PR Newswire)
Menopausal Hot Flashes Worse for Heavier Women Dec 29, 2007
Such so-called "vasomotor symptoms" had previously been thought to be less common in heavier women at menopause, because body fat can convert male hormones into estrogen, Dr. Rebecca C. Thurston of the University of Pittsburgh School of Medicine and colleagues note ... However, there is mounting evidence that heavier women may actually experience more vasomotor symptoms with menopause, the researchers add in their report in the American Journal of Epidemiology ... Fifty-nine percent reported... (Newsmax)
Altered sex hormone levels, higher body temp affects sleep quality in postmenopausal women Dec 2, 2007
Furthermore, several studies have shown that hot flashes and other vasomotor symptoms that influence sleep continue years beyond menopause in up to 40 percent of postmenopausal women. Thus, the sleep difficulties that emerge at menopause often do not abate and may become compounded by age-associated disruption of circadian and homeostatic processes that regulate sleep. (EurekAlert!)
Wyeth Presents New Phase 3 Data and Updates Regulatory Timing for NDA Filing of Bazedoxifene/Conjugated Estrogens Oct 6, 2007
"TSECs pair the benefits of estrogens with SERMs to create a distinct clinical profile, which may provide relief of hot flashes and vaginal dryness as well as bone and uterine protection." Update on NDA Filing Wyeth plans to submit its New Drug Application (NDA) to the U.S. Food and Drug Administration for bazedoxifene/conjugated estrogens in the second quarter of 2008 subject to the further analysis and successful completion of product formulation, bioequivalence and clinical studies, and other... (PR Newswire)
Hormone Therapy Boosts Sexual Interest But Not Memory, Study Suggests Sep 26, 2007
The study also found that women with vasomotor symptoms, such as hot flashes and night sweats, showed a reduction in symptoms and an improvement in overall quality-of-life when taking hormone therapy versus placebo. The study, which is the largest randomized trial to date examining hormone therapy and memory in midlife women, was stopped early due to declining enrollment that coincided with results of the Women's Health Initiative, which found that the associated health risks of the therapy... (Science Daily)
Diesel-Exhaust Inhalation in Men with Coronary Disease Sep 13, 2007
Six hours after exposure, vasomotor and fibrinolytic function were assessed by means of intraarterial agonist infusions ... Exposure to diesel exhaust did not aggravate preexisting vasomotor dysfunction, but it did reduce the acute release of endothelial tissue plasminogen activator (P=0. (New England Journal of Medicine)
Survey: Menopause Taking Toll on Couples' Sex Lives Aug 18, 2007
Some women experience vasomotor symptoms such as or night sweats, while others experience vaginal atrophy (vaginal narrowing or shrinkage), which can cause vaginal dryness and painful sex. If left untreated over time, vaginal atrophy ultimately can lead to chronic sexual dysfunction and/or physically uncomfortable sexual experiences, the survey said. (Fox News)
Noble Financial TWO DOUBLE-O-SEVEN Equity Conference Presenter Profiles Aug 18, 2007
BioSante's lead products include Elestrin(TM) (estradiol gel) developed through FDA approval by BioSante indicated for the treatment of moderate-to-severe vasomotor symptoms associated with menopause, marketed in the U.S. by Bradley Pharmaceuticals, Inc., BioSante's licensee, and LibiGel(R) (transdermal testosterone gel) in Phase III development by BioSante for the treatment of female sexual dysfunction (FSD). Also in development is Bio-T-Gel(TM), a testosterone gel for male hypogonadism, and an... (Yahoo! Wire -- Entertainment News)
Pfizer Inc UK Regulatory Announcement: Pfizer Says Growth in Phase II Portfolio Supports Goal of Tripling Phase III Portfolio by 2009 Aug 7, 2007
Pfizer also continues work on alpha-2-delta compounds for patients with neurological disorders, and it is proceeding with broad confirmatory development of PD-332334, now in Phase II, for the treatment of GAD. Pfizer scientists continue to believe that molecules with this mechanism of action are potentially important new therapies for the treatment of illnesses including insomnia and vasomotor symptoms. Pfizer also has several new approaches to the treatment of Alzheimer s disease in ongoing... (BusinessWire)
Wyeth: FDA wants more data on drug's effect on heart and liver Jul 24, 2007
"Wyeth remains committed to the development of Pristiq as a potential treatment for moderate-to-severe vasomotor symptoms associated with menopause," Stiles told reporters in a teleconference. "We will work with the agency, and we have not yet met with them, to satisfy its requests for additional data and move this medicine forward in the FDA review process.". (Newsday -- State)
Why Patients With Obstructive Sleep Apnea Are At Higher Risk For Cardiovascular Disease Jun 4, 2007
The OSA patients also had more apoptotic cells circulating in their bloodstreams and had vasomotor dysfunction. The OSA patients were given nasal CPAP treatment for eight weeks. (Science Daily)
Birth control pill FAQ: Benefits, risks and choices May 22, 2007
When you no longer need contraception, hormone therapy is a better option for managing uncomfortable menopausal vasomotor symptoms, including hot flashes and night sweats. RELATED. (MayoClinic.com)
IMS updated recommendations on postmenopausal hormone therapy May 16, 2007
HT remains the most effective therapy for vasomotor and estrogen-deficient urogenital symptoms ... Selective serotonin reuptake inhibitors, selective noradrenaline reuptake inhibitors and gabapentin are effective in reducing vasomotor symptoms in short-term studies. (EurekAlert!)
2 problems, 1 remedy Feb 21, 2007
"I really don't have patients that say Effexor helps with vasomotor symptoms.". Fisher of Wyeth says the company has done "really thorough trials for women for vasomotor symptoms like hot flashes .". (Newsday -- Business)
Clomiphene, Metformin, or Both for Infertility in the Polycystic Ovary Syndrome Feb 8, 2007
With the exception of pregnancy complications, adverse-event rates were similar in all groups, though gastrointestinal side effects were more frequent, and vasomotor and ovulatory symptoms less frequent, in the metformin group than in the clomiphene group. Conclusions Clomiphene is superior to metformin in achieving live birth in infertile women with the polycystic ovary syndrome, although multiple birth is a complication. (New England Journal of Medicine)
Estrogen Therapy For Hot Flushes Challenged: Progestin As Effective As Risk-laden Estrogen Feb 7, 2007
Both therapies reduced flushes and sweats -- together known as vasomotor symptoms (VMS) -- to one flush or sweat every third or fourth day. In addition, no participant experienced blood clots, heart attack, stroke or breast cancer during the study. (Science Daily)
Herbal menopause therapy gets a closer look Jan 11, 2007
"Remifemin is a safe and effective intervention for the relief of hot flashes and other vasomotor symptoms associated with menopause," Liske said. Treatment has many fans. (USA Today -- News)
