More on Anti–Glomerular Basement Membrane Disease after Alemtuzumab Dec 4, 2008
14 issue)1 report on two patients (one with multiple sclerosis and the other with antineutrophil cytoplasmic antibody associated vasculitis) in whom anti glomerular basement membrane nephritis developed after treatment with alemtuzumab. The authors speculate that the emergence of autoreactive B cells rather than persistently suppressed T cells after alemtuzumab therapy might have caused autoimmunity in their patients. (New England Journal of Medicine)
Irina Slutskaya too busy to think about retirement Nov 22, 2008
She was also later diagnosed with vasculitis, an inflammation of blood vessels that can cause major vascular organs to deteriorate. "I really like exhibitions and I really like to skate for people," she said. (Anchorage Daily News)
The Binding Site Announces Trading Update for Year Ended September 30th 2008 Nov 11, 2008
" Notes to Editors: About The Binding Site The Binding Site Ltd. is a British based company specialising in the research, development and production of immunodiagnostic kits and reagents. The Binding Site manufactures a wide range of high quality and innovative products used in clinical laboratories world-wide. The business is divided into three main areas:- Freelite(TM), a novel and highly significant assay increasingly used for the diagnosis and monitoring of multiple myeloma (MM), a cancer of... (PR Newswire)
All aboard to the Imagination Library Oct 23, 2008
Visit our sister newspaper sites. Proudly serving Marlin and Falls County, Texas since 1890 ; Thursday, October 23, 2008. (Marlin Democrat, TX)
Understanding Transverse Myelitis Oct 17, 2008
Tranverse myelitis is an inflammatory neurological condition that can occur in multiple sclerosis, vasculitis and other autoimmune conditions ... Transverse myelitis is caused by multiple sclerosis; infections (particularly Lyme disease, cytomegalovirus, chickenpox, mycoplasmal infection, tuberculosis, rubella, viral hepatitis, syphilis and viral meningoencephalitis); autoimmune conditions of vasculitis, SLE, Sjogren s syndrome, sarcoidosis, and APS; abnormalities of blood flow or conditions of... (Suite101.com)
Arteries From Distinct Regions Of The Body Have Unique Immune Functions Sep 7, 2008
Their findings explain why vascular diseases affect different parts of the arterial network and could help doctors fine-tune the treatment of such diseases as atherosclerosis and vasculitis. Atherosclerosis causes heart attacks and strokes because it occurs preferentially in arteries supplying the heart and the brain. (Science Daily)
President May Require Attention In Another Hospital Sep 7, 2008
Dr. Edward Oparaoji, the Global Medical Affairs Chief of Nephrology Section at the Shire Pharmaceuticals in Pennsylvania, United States, described CSS as "rare" and one of many forms of vasculitis - diseases characterised by inflammation of blood vessels, especially small arteries and veins. He said the cause of the CSS syndrome is not known, but it involves an abnormal over-activation of the immune system in a person. (Guardian News, Nigeria)
Yar'Adua back... 'very soon' Sep 4, 2008
Dr. Edward Oparaoji, the Global Medical Affairs Chief of Nephrology Section, at the international medical firm Shire Pharmaceuticals, in Pennsylvania USA, said CSS "is rare and one of many forms of vasculitis- diseases characterised by inflammation of blood vessels, especially small arteries and veins.". However, a UN document made available at the UN headquarters in New York indicated that the President is expected to address the General Assembly of the world body on September 24, a day after... (Guardian News, Nigeria)
Protein Complementarity May Offer New Insights Into Autoimmune Diseases Aug 15, 2008
14, 2008) The discovery of "complementary" antibodies against plasminogen in patients with blood vessel inflammation caused by anti-neutrophil cytoplasmic autoantibodies (ANCAs) may lead to new approaches to research, testing, and treatment of ANCA vasculitis and other autoimmune diseases, suggests a new article ... The researchers looked for complementary proteins in a group of patients with a rare autoimmune disease called ANCA vasculitis ... In patients with ANCA vasculitis, the ANCAs attack... (Science Daily)
Shauna Karen Carson McCurdyNov. 24, 1953 - July 23, 2008 Jul 31, 2008
Memorial contributions may be made to the Vasculitis Foundation, PO Box 28660, Kansas City MO 64188 (). Because I could not stop for Death. (Ontario Argus Observer, OR)
Clyde T. Johnston Jun 23, 2008
In lieu of flowers, the family requests donations are made to the Vasculitis Foundation (www. vasculitisfoundation. (New Iberia, LA)
Neuromyelitis Optica Jun 5, 2008
Devic's Syndrome: Multiple Sclerosis Variant Often Confused with MS. NMO antibodies are key to diagnosis. (Suite101.com)
LETTER: Arthritis Walk will help fight Sjogren's Syndrome May 3, 2008
When internal organs are involved, it can cause arthritis, myositis, gastrointestinal problems, interstitial cystitis or renal problems, vasculitis and neurologic symptoms that cause central nervous system disorders such as cranial and peripheral neuropathies. This condition also causes cognitive dysfunction and memory problems as the disorder progresses, along with greater risk of developing lymphoma. (Mattoon Journal-Gazette, IL)
Gemma didn't have to die Apr 20, 2008
Kawasaki disease, an uncommon illness that mostly affects children under five, causes inflammation of small blood vessels known as vasculitis. In extreme cases the coronary arteries swell, which can block the blood supply to the heart. (Sydney Morning Herald -- Australia)
* Pediatricians warn parents against Kawasaki disease Apr 11, 2008
First discovered in 1967 by Tomisaku Kawasaki in Japan, the disease is a poorly understood self-limited vasculitis that affects many organs, including the skin and mucous membranes, lymph nodes, blood vessel walls and the heart. Lu said parents and pediatricians should pay extra attention if children in their care have a fever for more than five days and show other symptoms such as a rash, swollen hands and feet, red eyes, swollen lymph glands in the neck, and irritation and inflammation of the... (Taipei Times, Taiwan -- World)
Some Docs Latching Onto Leeches Mar 5, 2008
Dr. Dong-Ha Han nicknamed "doctor leech" for his eight years of research on medical leeches says he can treat patients with vasculitis, skin ulcer, atopic dermatitis, rheumatic arthritis, migraine and gout. His toolbox includes leeches that are starved for six months. (ABC News)
A Nazi past casts a pall on name of a disease Jan 23, 2008
"The name adds insult to injury," said Shaw, who prefers calling her condition vasculitis, the broader term for the family of diseases that includes Wegener's ... At the moment, the most precise candidate is ANCA-associated granulomatous vasculitis, which does not exactly trip off the tongue. (International Herald Tribune -- Health)
Biomarkers For Inflammatory Disease Dec 8, 2007
Kawasaki disease, an acute, self-limited vasculitis, is the leading cause of acquired heart disease in children in developed countries, but its aetiologic and pathogenic mechanisms remain unclear. A team of researchers led by David Relman, Stanford University, US, and Jane Burns, University of California at San Diego, US, characterized the gene expression patterns that occur in the blood cells of patients with this disease. (Science Daily)
Existing Drugs Show Promise For Treating End-stage Renal Disease In Lupus Nov 29, 2007
At the end of the eight-week study, 90 percent of the mice in the non-treatment group had renal vasculitis, inflammation of the tiny blood vessels in the kidney that can lead to kidney failure, compared to 30 percent in the treatment group. In addition, 60 percent in the non-treatment group had high levels of protein in the urine (a sign of kidney disease), compared to 22 percent in the treatment group. (Science Daily)
United States Nov 18, 2007
He has three auto-immune disorders: Crohn's disease, a chronic inflammation of the bowel, total alopecia, and cerebral vasculitis, an immune system-related narrowing of blood vessels in the brain. The new tests suggest I inhaled about 4,000 particles of DU,' Donnelly says. (Guardian Unlimited)
Charleston woman diagnosed with rare disease reaches out to help others Nov 3, 2007
It is a form of vasculitis, a disorder that causes inflammation in blood vessels and affects various organs, including lungs, upper respiratory and kidneys. The condition is believed to affect about one in 1 million people. (Mattoon Journal-Gazette, IL)
Doctor says Wegener's granulomatosis is difficult to diagnose, requires aggressive treatment Nov 3, 2007
It is an example of vasculitis, a condition of inflammation of the blood vessels, he said ... Parkison to start vasculitis support group ... A Charleston woman diagnosed in March 2005 with a rare disease called Wegener s granulomatosis is working toward becoming a chapter leader for the Vasculitis Foundation. (Mattoon Journal-Gazette, IL)
Antiphospholipid Syndrome Oct 21, 2007
Pauci-immune vasculitis. APS Associated Nephropathy. (Suite101.com)
Mayo Clinic clarifies diagnosis for serious blood vessel disease of brain and spinal cord Oct 19, 2007
Primary central nervous system vasculitis (PCNSV) can best be identified through a combination of diagnostic techniques consisting of angiography (imaging the cerebral arteries), brain biopsy and other laboratory studies ... Primary central nervous system vasculitis is difficult to diagnose because it is not a single disease, but a variable syndrome that appears to consist of several distinct subsets of different diseases that can mimic other less-serious conditions, thus eluding treatment ...... (EurekAlert!)
Rams soccer standout battles West Nile Virus Oct 13, 2007
According to the National Institute of Allergy and Infectious Diseases, Wegener's granulomatosis is an uncommon disease in which the blood vessels are inflamed (vasculitis). This inflammation damages important organs of the body by limiting blood flow to those organs and destroying normal tissue. (Rio Rancho Observer, NM)
Lessons from a Genomewide Association Study of Rheumatoid Arthritis Sep 21, 2007
Occasionally there is systemic involvement, which can include vasculitis in various organs and pulmonary fibrosis. The disease has multifactorial causes to which genetic and environmental factors are thought to contribute. (New England Journal of Medicine)
Potential New Way to Treat Inflammatory Disease Found Sep 14, 2007
If the drugs effects are confirmed in clinical trials, they could be used against several types of inflammation that include acute vasculitis, an inflammation of blood vessels that can affect any organ in the body. Also, the drugs have been used successfully to treat acute coronary syndrome, which refers to certain types of heart attack and unstable angina. (Newsmax)
A Woman with Headaches, Weakness, and Strokelike Episodes Jul 12, 2007
NEJM -- Case 21-2007 -- A 58-Year-Old Woman with Headaches, Weakness, and Strokelike Episodes. Please for full text and personal services. (New England Journal of Medicine)
Immunosuppressant Drugs Jul 5, 2007
Cyclophosphamide (Cytoxan), which is primarily used in systemic lupus erythematosus, autoimmune hemolytic anemia, Wegener s granulomatosis, and other forms of vasculitis. Cyclosporine (Sandimmune, Neoral) is primarily used in psoriasis soriasis. (Suite101.com)
Communication between Physicians and Patients in the Era of E-Medicine Jun 14, 2007
Dr. Stone, formerly director of the Vasculitis Center and an associate professor of medicine at Johns Hopkins University School of Medicine, Baltimore, is now a deputy editor for rheumatology at UpToDate, Waltham, MA.. . (New England Journal of Medicine)
Test Case Linking Vaccines and Autism Reaches Federal Court Jun 5, 2007
Within days, Ryan had an intense allergic reaction and developed vasculitis. "That means the valves in your veins leak," Gaudino says. (Law.com)
Kawasaki's Disease May 13, 2007
Immune-Mediated Vasculitis in Children ... Another perplexing fact is that , unlike other forms of vasculitis, patients with Kawasaki s disease are not easily treated with corticosteroids. (Suite101.com)
Summary for Patients May 1, 2007
Giant cell arteritis (GCA, also called temporal arteritis) involves inflammation of large and medium-sized arteries (vasculitis). This condition occurs in elderly people and can lead to sudden blindness. (Annals of Internal Medicine)
* Sports Briefs Apr 12, 2007
Slutskaya has been treated for vasculitis, an ailment which results in the inflammation of the blood vessels. ICE HOCKEY Blackhawks win lottery The Chicago Blackhawks won the National Hockey League draft lottery on Tuesday, gaining the first overall selection in June's draft. (Taipei Times, Taiwan -- World)
What is Lupus? Apr 4, 2007
Inflammation of the blood vessels, known as vasculitis, can develop in many organs impairing blood supply to the tissue. This inadequate oxygen supply to the cells can lead to further inflammation and destruction of the tissue. (Suite101.com)
Human Parvovirus B19 Infection Apr 4, 2007
Human Parvovirus B19 has been linked to a number of different autoimmune diseases, including vasculitis and connective tissue disorders ... The immune response in Parvovirus infection also causes the induction of tumor necrosis factor alpha (TNF- ), a cytokine involved in the development of ANCA positive vasculitis syndromes. (Suite101.com)
Cogan's Syndrome Mar 30, 2007
Other symptoms include vasculitis, nausea, vertigo, poor balance, fever, fatigue, weight loss, vomiting, light sensitivity, and a bilateral blurring of vision ... Vasculitis in Cogan s syndrome can cause major organ damage, and in rare instances it can be fatal ... Vasculitis, if present, can be detected with imaging tests and confirmed with tissue studies. (Suite101.com)
An elusive diagnosis with a risk of cancer Mar 29, 2007
Recent studies have quantified the risk, finding that dermatomyositis patients face a threefold risk of cancer, while patients with polymyositis face a 40 percent increase in risk, said Dr. Stuart M. Levine, co-director of the Hopkins vasculitis center and an author of a recent paper on the subject ... Levine, of the vasculitis center, said the muscle cells might be like "innocent bystanders," accidentally harmed during the immune system's assault on the tumor. (International Herald Tribune -- Health)
Rheumatoid Arthritis Today Mar 26, 2007
Systemic effects of RA include cardiac (heart) involvement including pericarditis (inflammation of the sac surrounding the heart), myocarditis (inflammation of the heart muscle), and rheumatic nodules in myocardial tissue; cutaneous vasculitis, neurological disease (mononeuritis multiplex, a condition of neuropathy affecting multiple systems such as the nerves of the hands and feet), and diffuse lung problems such as pleural effusion and pulmonary vasculitis. About 30 percent of patients develop... (Suite101.com)
Churg-Strauss Syndrome Mar 22, 2007
A Unique Combination of Vasculitis, Eosinophilia, and Asthma ... Small vessel necrotizing (causing tissue damage and destruction) Vasculitis ... These P-ANCA or myeloperoxidase autoantibodies, are also seen in other conditions of vasculitis affecting small to medium vessels. (Suite101.com)
Vasculitis Update Mar 21, 2007
Vasculitis includes more than 20 organ specific and systemic disorders that cause inflammation in the veins and arteries as well as the organs that these vessels supply. Vasculitis, which is sometimes called angiitis, is a condition of blood vessel inflammation ... Conditions of vasculitis cause inflammation of veins and arteries along with their smaller tributaries, the venules and arterioles. (Suite101.com)
Mixed Connective Tissue Disease Feb 25, 2007
Complications include fever, which occurs as a sign of infection, vasculitis, pancreatitis, appendicitis, bowel perforations, trigeminal neuralgia, respiratory distress syndrome, stroke, and secondary Sjogren s syndrome. Although some researchers recognize MCTD as a subset or early stage of SLE, most researchers consider MCTD a distinct clinical entity with infrequent renal complications. (Suite101.com)
Connective Tissue Disorders Feb 24, 2007
Various forms of vasculitis including , and. Mixed connective tissue disease. (Suite101.com)
Book Review "Don't Leave Me This Way" Feb 21, 2007
After a diagnosis of vasculitis, a specialist Garrison nicknames "Dr. Jerk" recommends chemotherapy once a month for the rest of her life. Garrison initially resists treatment with the strong chemicals but reluctantly consents. (Galesburg The Paper, IL)
Benefits of a Gluten-Free Diet Feb 20, 2007
The Living Without article "All in your head" lists the following as conditions possibly associated with gluten: congenital heart disease, recurrent pericarditis (inflammation of the sack around the heart), lung disease, inflammatory bowel disease, autoimmune hepatitis (liver disease), primary biliary cirrhosis (gallbladder dysfunction), Addison's disease (kidney and adrenal dysfunction), systemic lupus erythematosus (an autoimmune disease), vasculitis (inflammation of the blood vessels),... (Suite101.com)
The Riddle of Kawasaki Disease Feb 15, 2007
How can an illness look like an infectious disease but not have a recoverable agent; look like an immune-mediated vasculitis but not be easily treated with corticosteroids; and look like a benign, self-limited illness but be the leading cause of acquired heart disease in children. The answers to the riddle continue to elude us. (New England Journal of Medicine)
Rashes and Hives Feb 5, 2007
Persons with autoimmune disorders, especially thyroid disorders, lupus and Sjogren's, are at risk for rashes, hives and urticarial vasculitis ... Urticarial Vasculitis ... Chronic urticaria may also be associated with a leukocytoclastic (white blood cell-mediated) vasculitis confined to skin or to a wider area of connective tissue. (Suite101.com)
Inflazyme Pharmaceuticals Ltd., to Appear On MN1.com Jan 10, 2007
Inflazyme's proprietary class of PDE4 Inhibitors, which could also be used to treat asthma and COPD, do not cause nausea or emesis (vomiting) in human subjects in clinical studies or vasculitis (inflammation of the blood vessels in the body) in preclinical studies. These compounds are at the research stage and could be readily advanced into the clinic. (Primezone Releases)
Explore Stroke Symptoms Jan 4, 2007
Strokes: Causes, Symptoms And Treatment, FYI: Learn More About The Causes Of And Medical Care For Strokes - CBS News. Strokes: Causes, Symptoms And Treatment. (CBS News -- Evening News)
