Eisai's Commitment to Oncology Demonstrated by Clinical Data to be Presented at ASCO Annual Meeting May 16, 2008
In October 2006, Eisai acquired four products mainly for the treatment of cutaneous T-cell lymphoma, as well as an oncology specialty sales force from Ligand Pharmaceuticals. This provided Eisai with an initial commercial infrastructure for oncology products. (PR Newswire)
Wisconsin Girl, 9, Diagnosed With Cancer for Third Time Apr 22, 2008
Emily Miller was diagnosed with acute lymphocytic leukemia in 2002, overcame it in 2005 and was in remission until April of last year when she was diagnosed with T-cell lymphoma. She was excited to finish chemotherapy this August. (Fox News)
COLUMN: Benefits to help Landon Stuckeys of the world bring out the best in us Apr 19, 2008
Landon has T-cell lymphoma cancer. The best way to understand is with the word chemotherapy. (Mattoon Journal-Gazette, IL)
The good and bad side of anti-cancer compounds Apr 11, 2008
The Food and Drug Administration recently approved an HDAC inhibitor called SAHA (suberoylanilide hydroxamic acid) for treating a form of T-cell lymphoma which means that the drug will likely be given off-label for other types of tumors. While this marks a major step forward in the therapeutic use of HDAC inhibitors, Hiebert notes, we think they can be used better. (EurekAlert!)
Superman Whitaker loses battle with cancer North Stafford High School student dies after battle with cancer Apr 9, 2008
He had non-Hodgkins T-cell lymphoma, which affects the cells that fight infection, but he rebounded after initial treatments to earn a position on the school's baseball team. There were times he hurt so badly he could barely walk, but Justin still played, and cheered on others when he couldn't, said friends and family. (Fredericksburg.com, VA)
A Gift of Life Turns Deadly Apr 3, 2008
But it was only after the transplants were performed that autopsy results revealed Alex had a deadly cancer known as anaplastic T-cell lymphoma not bacterial meningitis. "We were shellshocked by the whole situation," Jim Koehne said on "GMA" today. (ABC News)
A Man with Fever, Abdominal Pain, and Pancytopenia after Renal Transplantation Mar 15, 2008
Hepatosplenic T-Cell Lymphoma. Infectious-Disease Considerations. (New England Journal of Medicine)
Inverted DNA turns quiet developmental gene into a potent driver of t-cell lymphoma Feb 28, 2008
Public release date: 27-Feb-2008. Contact: Greg Lester. (EurekAlert!)
Click here to read more. Feb 4, 2008
North Stafford High School senior Justin Whitaker, who is battling T-cell lymphoma, smiles during a graduation ceremony held for him at the school on Saturday ... Justin was 16 and a popular member of the baseball team when he was first diagnosed with non-Hodgkins T-cell lymphoma. (Fredericksburg.com, VA)
Stafford teen is a study in perseverance Popular North Stafford student rebounds quickly after bone-marrow transplant Jan 7, 2008
The North Stafford student has been the poster child of positive thinking since he was diagnosed with an aggressive cancer called T-cell lymphoma in June 2006. After initial treatments, he fought his way back onto the school's varsity baseball team. (Fredericksburg.com, VA)
Firefly Genes In Mice Allow Testing Of New Therapy Against Lymphoma Dec 29, 2007
The new study looked at ATLL, adult T-cell lymphoma and leukemia, a form of cancer where it is particularly hard to gauge the disease's progress, and where the patients' prognosis is generally poor ... The images above show mice at four and five weeks, respectively, after they had acute T-cell lymphoma and leukemia (ATLL) cells, containing the firefly gene, injected into their abdomens. (Science Daily)
BioCryst reports positive results for cancer drug Dec 15, 2007
According to interim data collected during clinical trials, the oral form of forodesine had a 39 percent response rate in 36 subjects with T-cell lymphoma. CEO Jon Stonehouse said he was pleased with the results, which come a week after the Birmingham-based company discontinued clinical studies of the intravenous version. (Birmingham Business Journal)
A Woman with Painful, Ulcerated Skin Lesions Dec 13, 2007
Aggressive Epidermotropic CD8+ Cytotoxic T-Cell Lymphoma. Interpretation of This Case. (New England Journal of Medicine)
CuraGen and TopoTarget Report Belinostat Results Presented at ASH and Provide Regulatory Update Following End-of-Phase II Meeting with FDA Dec 11, 2007
- Conference call to be hosted on Tuesday, December 11th at 9:00 a.m. Eastern time - - Encouraging clinical results presented at ASH from the ongoing Phase II trial in T-cell lymphomas - - Positive End-of-Phase II meeting held with the FDA for belinostat in PTCL - BRANFORD, Conn. Dec. 10 /PRNewswire-FirstCall/ -- CuraGen Corporation (Nasdaq: ), a clinical-stage biopharmaceutical company focused on oncology, and TopoTarget A/S (Copenhagen Stock Exchange: TOPO) announced today that updated... (PR Newswire)
ZOLINZA (vorinostat) in combination with bortezomib demonstrated clinical activity Dec 9, 2007
Based on these initial results presented for the first time, Merck is evaluating plans to accelerate testing of ZOLINZA in combination with bortezomib in the randomized clinical trial setting to further define the clinical activity in relapsed or refractory multiple myeloma," said Dr. Garcia-Vargas. ### About ZOLINZA ZOLINZA is the first histone deacetylase (HDAC) inhibitor approved by the U.S. Food Administration (FDA) for the treatment of cutaneous manifestations in patients with cutaneous... (EurekAlert!)
Twelve DOXIL(R) Clinical Studies to be Presented at American Society of Hematology Annual Meeting Dec 8, 2007
ATLANTA, Dec. 7 /PRNewswire/ -- Ortho Biotech today announced that 12 clinical studies of DOXIL(R) (doxorubicin HCl pegylated liposome injection) will be presented at the 49th annual meeting of the American Society of Hematology (ASH) at the Georgia World Congress Center on December 8-11, 2007. IMPORTANT SAFETY INFORMATION BOXED WARNINGS Cardiotoxicity, infusion reaction, myelosuppression, liver impairment, Substitution -- The use of DOXIL may lead to cardiac toxicity. (PR Newswire)
Novartis Makes Plans to Release Four New Cancer Drugs by 2011 Dec 6, 2007
Others drugs Novartis aims to launch by 2011 are ASA404 for non-small-cell lung cancer, SOM230 for a rare group of neuroendocrine tumors and LBH589 for cutaneous T-cell lymphoma. The experimental drugs could fail in human tests or be rejected by regulators, including the U.S. Food and Drug Administration. (Wall Street Journal)
Radnor pharmaceutical company gets $14.5M in funding Nov 27, 2007
Yaupon is developing possible treatments for T-cell lymphoma, addiction and pain. The company's lead drug is Clearazidea, a topical agent for cutaneous T-cell lymphoma. (Philadelphia Business Journal, PA)
Top 10 Stocks Under $10 Oct 29, 2007
Biocryst told Wall Street on Oct. 12 that it has initiated enrollment of the trial of its lead oncology drug candidate, forodesine HCL, in the treatment of patients with cutaneous T-cell lymphoma (CTCL). The multinational trial will be conducted under a special agreement between the U.S. Food and Drug Administration and BioCryst. (Forbes)
Celiac Disease Oct 25, 2007
Enteropathy-Associated T-Cell Lymphoma. Refractory Celiac Disease. (New England Journal of Medicine)
BioCryst enrolling patients to test cancer drug Oct 13, 2007
is enrolling patients with T-cell lymphoma to test its cancer drug forodesine HCL. ... Eligible patients are those with T-cell lymphoma whose symptoms are persistent, progressive or recurrent during or after treatment. (Birmingham Business Journal)
Have you been misdiagnosed? Sep 20, 2007
Her doctor assured her it was right: two labs had confirmed the subcutaneous panniculitis-like T-cell lymphoma. Against her doctor's orders, Torrey delayed chemo and went to another oncologist, who sent a tissue sample to the National Institutes of Health. (CNN)
Physician, Heal Thyself Sep 11, 2007
On the blog now: Updated at 6:37 AM. Updated: 1:07 AM 09/11/07. (Townhall.com)
FACES OF HOPE Aug 27, 2007
He became an American immigrant success story, graduating with honors from Harvard Medical School and pioneering T-cell lymphoma research. About half of lymphoma patients can be cured or have their cancer sent into remission, as long as they get the right treatment from the start, he said. (Las Vegas Sun)
• Aetna Leader: A Proven Fighter Aug 26, 2007
The journey began when Eric was 16 and diagnosed with Gamma Delta T-cell lymphoma, a type of cancer of the T-cells, which are supposed to protect the body from infection. The cancer spread to his lymph nodes and bone marrow. (FOX61, CT)
Allos Therapeutics Reports Second Quarter 2007 Financial Results Aug 7, 2007
The Company's lead product candidate, PDX (pralatrexate), is a novel antifolate currently under evaluation in a pivotal Phase 2 trial in patients with relapsed or refractory peripheral T-cell lymphoma. The Company is also investigating PDX in patients with non small cell lung cancer and a range of other lymphoma sub-types. (Canada Newswire)
Rates of Lymphoma Increase Over 30 Years Jul 20, 2007
Chicago, IL - infoZine- Cutaneous T-cell lymphoma occurs when certain cells of the lymph system (called T lymphocytes) become cancerous and affect the skin ... D., of the VA Medical Center, Rhode Island Hospital, and Brown University, Providence, R.I., used data from 13 cancer registries of the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute to describe incidence trends in cutaneous T-cell lymphoma from 1973 through 2002 ... Scientists have been... (Kansas City infoZine)
Rates of Rare Lymphoma Increasing Jul 20, 2007
THURSDAY, July 19 (HealthDay News) -- The incidence of a rare cancer called cutaneous T-cell lymphoma has increased threefold over the past 30 years in the United States, a new study found ... The reasons for this dramatic increase in the rates of cutaneous T-cell lymphoma aren't known, Criscione said ... In cutaneous T-cell lymphoma, cells of the lymph system called T lymphocytes become cancerous, affecting the skin. (Health-Finder)
Cutaneous T-cell Lymphoma On The Rise, Research Shows Jul 18, 2007
Cutaneous T-cell lymphoma, a rare and mysterious cancer, is on the rise, according to the first nationwide study of the disease in a decade. The study, conducted by researchers at the Providence VA Medical Center and The Warren Alpert Medical School of Brown University, found that 4,783 new cases of cutaneous T-cell lymphoma were diagnosed between 1973 and 2002, the period under review ... Cutaneous T-cell lymphoma is caused by the uncontrolled growth of a type of white blood cell within the... (Science Daily)
BioCryst Pharmaceuticals Inc. Jul 10, 2007
The clinical trial, expected to start during the third quarter of 2007, is intended to determine the success rate of the drug that is taken orally to treat cutaneous T-cell lymphoma leukemia. The proposed trial will enroll patients with certain stages of T-cell lymphoma leukemia that is persistent, progressive or recurrent after treatment with at least three systemic therapies. (Birmingham Business Journal, AL)
Heern’s standing ovation was about more than just a free throw Jun 19, 2007
Ross Heern spent November through January in St. Jude s Children s Hospital after being diagnosed Nov. 1, 2006, with non-Hodgkin s lymphoblastic T-cell lymphoma a cancer of the immune system ... They did a needle biopsy, and on Nov. 1, they told us he had non-Hodgkin s lymphoblastic T-cell lymphoma. (West Frankfort Daily American, IL)
It Doesnt take Wealth to Leave an Inheritance Jun 16, 2007
Later, as a civilian physician, he was stunned to learn he suffers from a rare T-cell lymphoma, which his physician blames on exposure to TCE. Past contaminated water at Camp Lejeune is suspected in the death and illness of military and their families. (AP Photo/Gros Family). (Townhall.com)
Hope riding on NY marijuana bill Jun 15, 2007
"If something could help someone in severe pain, why should they be denied it?" said Greene, who also has T-cell lymphoma, a form of blood cancer. "I don't think the government has the right to make that choice.". (Newsday)
Nonresponsive Celiac Disease Due to Inhaled Gluten Jun 14, 2007
Adherence to diet is crucial for intestinal mucosal recovery, relief of symptoms, and prevention of intestinal T-cell lymphoma. 1 The amount of gluten needed to cause mucosal injury varies. (New England Journal of Medicine)
Marine Families Want $4B for Toxic Water Jun 13, 2007
Later, as a civilian physician, he was stunned to learn he suffers from a rare T-cell lymphoma, which his physician blames on exposure to TCE.. Gros's weak immune system now keeps him home. (Fox News)
Health Officials Hope a Study Will Reveal The Cause. Jun 12, 2007
He suffers from a rare T-cell lymphoma, which his physicians blame on exposure to TCE. ... Later, as a civilian physician, he was stunned to learn he suffers from a rare T-cell lymphoma, which his physician blames on exposure to TCE.. (The Ledger)
ECP may be effective in treating Crohn's disease May 26, 2007
The Therakos UVAR"XTS instrument, in conjunction with 8-methoxypsoralen, is the only ECP system approved by the Food and Drug Administration for the palliative treatment of the skin manifestations of Cutaneous T-cell Lymphoma that is unresponsive to other forms of treatment. The UVAR"XTS is also the only device in Europe that is CE marked for ECP.. ECP as performed on UVAR" systems has an established safety profile and more than 500,000 treatments have been conducted since 1987. The most... (EurekAlert!)
Orbiting factories take off May 7, 2007
" Too bad it didn't work out that way. The shuttle never lived up to the expectations of Stein and others, and there is still no low-cost way to get payloads and people into space. Yet in spite of all the disappointments, there are signs that the long-awaited space manufacturing revolution may finally be ready to take off. One of the original justifications NASA used for building the space station in the mid-1980s was that it would provide a unique environment for certain types of specialized... (San Francisco Chronicle -- Opinion)
Relay for Life looms with two honorary members chosen May 4, 2007
In November 2006 the Heern family of Thompsonville Illinois saw their otherwise normal life turned upside down when their son, Ross, was diagnosed with a form of Hodgkins T-Cell Lymphoma. What began as a visit to a local clinic on a Tuesday afternoon, to have a doctor examine Ross for some shortness of breath he was experiencing while running cross country for Thompsonville High School, became a fight for his life. (West Frankfort Daily American, IL)
Massey researchers induce cell death in leukemia Apr 17, 2007
Gloucester Pharmaceuticals is conducting a pivotal phase II study of romidepsin for patients with cutaneous T-cell lymphoma (CTCL) and has initiated a pivotal phase II study for patients with peripheral T-cell lymphoma (PTCL). Romidepsin has received Orphan Drug Designation from the Food and Drug Administration (FDA) for the treatment of non-Hodgkin T-cell lymphomas, which includes CTCL and PTCL. In addition, the European Agency for the Evaluation of Medicinal Products (EMEA) has issued Orphan... (EurekAlert!)
Transgene, Roche Enter Potential $293M Alliance On HPV Vaccine Apr 14, 2007
And TG 1042, an adenovector virus-based product delivering interferon gamma, is in Phase II trials for cutaneous T-cell lymphoma. Transgene intends to keep rights to that product, which addresses a smaller market, he said. (BioWorld Online)
BioCryst halts trial of cancer drug Mar 28, 2007
Stonehouse said BioCryst will channel resources to using Fodosine to treat cutaneous T-cell lymphoma, or CTCL. That could provide the fastest route to marketing approval of the drug, he said. "The results in treatment of CTCL with the oral formulation of Fodosine remain encouraging and we believe that this decision will allow us the greatest chance of getting Fodosine to a larger number of patients quickly," Stonehouse said. (Birmingham Business Journal)
When a popular North Stafford High School baseball player got cancer, the school community stepped up to help him. Feb 27, 2007
Soon after he recovered, he found a lump on his neck that turned out to be T-cell lymphoma. The aggressive cancer affects cells that fight infection. (Fredericksburg.com, VA)
Keep Going Hall of Famers - exhibit determination, perseverance, can-do attitude Feb 20, 2007
After Nicholas Marriam of Clayton, N.C., finished his treatment for T-Cell Lymphoma cancer, he decided he could help other kids going through the same thing. He started a local effort to deliver gift bags along with hope and courage to hospitalized children. (McKinney Courier-Gazette, TX)
BioCryst lymphoma drug takes step toward European market Feb 7, 2007
Fodosine, BioCryst's lead oncology candidate, is currently in clinical trials for the treatment of cutaneous T-cell lymphoma (CTCL). The EMEA's Committee for Orphan Medicinal Products put Fodosine on track toward the European market. (Birmingham Business Journal)
Ontario to treat autoimmune disorders Jan 19, 2007
The photopheresis machines will treat patients with chronic post-transplant graft versus host disease who have failed to benefit from other treatments, in addition to those with advanced, cutaneous T-cell lymphoma that is resistant to treatment, an Ontario government source said last night. The government provided funding to purchase the new two machines after a recommendation received from the Ontario health technology advisory committee. (Globe and Mail -- National)
