The MOTHERS Act: Thalidomide Revisited? May 24, 2008
The MOTHERS Act: Thalidomide Revisited. The MOTHERS Act: Thalidomide Revisited. (PR Newswire)
Treating SSRI-resistant Depression Mar 28, 2008
Papakostas and colleagues compared two strategies for treating symptoms of major depressive disorder that do not respond to treatment with a selective serotonin reuptake inhibitor (SSRI) antidepressant: either switching to a second SSRI or to a non-SSRI antidepressant. Some common SSRI antidepressants are fluoxetine (Prozac), citalopram (Celexa) and sertraline (Zoloft), while examples of a few common non-SSRI antidepressants are venlafaxine (Effexor) and buproprion (Wellbutrin, Zyban). (Science Daily)
Young male sucide rate at a 30 year low say researchers Feb 18, 2008
The second study finds no effect on suicide of the recent restrictions on antidepressant prescribing to children and adolescents in the UK. They analysed three separate sets of data between 1993 and 2006 (SSRI antidepressant prescriptions to 12-19 year olds in the UK, annual deaths from suicide in 12-17 year olds in England and Wales, and hospital admissions for self-harm in 12-17 year olds in England). But they found no evidence of a temporal association between trends in antidepressant... (OnMedica)
Depressed Mice Reveal Critical Chemical Pathway For Treatment Feb 9, 2008
These patients often show resistance to treatment with SSRI antidepressant drugs. Mice with the mutation had 80 percent less serotonin in their brains than normal mice and exhibited behavioral changes that mirror the symptoms of humans with low serotonin. (Science Daily)
Depression and cardiovascular disease Oct 16, 2007
In addition, the Canadian Cardiac Randomized Evaluation of Antidepressant and Psychotherapy Efficacy, a randomized, controlled, 12-week, parallel-group trial (CREATE) (Lesperance et al., 2007), was the first trial specifically designed to evaluate the short-term efficacy and tolerability of 2 depression treatments in patients with CAD: citalopram, a first-line SSRI antidepressant and interpersonal psychotherapy (IPT), a short-term, manual-based psychotherapy focusing on the social context of... (EurekAlert!)
Spectrum Pharmaceuticals' Board of Directors Elected at Annual Stockholders Meeting Jul 21, 2007
-- Was a key part of the commercial launch of the leading anti-fungal agent Diflucan, the number one selling SSRI antidepressant Zoloft, and the novel alpha-blocker Cardura used for benign prostate hypertrophy. -- Responsible for the formation of a strategic alliance between Pfizer and Eisai related to the clinical development and commercialization of Aricept for Alzheimer's disease, the creation of a co-development and co-promotion agreement between Pfizer and Park Davis for Lipitor, and the... (PR Newswire)
Antidepressants safer than believed during pregnancy Jul 1, 2007
Major concerns over depression drugs taken during pregnancy surfaced in the fall of 2005, when GlaxoSmithKline, the maker of the SSRI antidepressant Paxil, found that pregnant women who were on the drug had an increased chance of having babies with holes in their hearts. In their studies, women on the medication had a 1. (abc13.com)
Depression Drugs May Lead to Apathy in the Elderly Mar 21, 2007
NEW YORK (Reuters Health) - Among depressed older adults, use of an SSRI antidepressant like Prozac may lead to apathy, even though it relieves symptoms of depression, clinicians in Canada report ... In the Baycrest Centre for Geriatric Care's Day Hospital Database, the Canadian team identified 384 elderly depressed patients; 160 were treated with an SSRI antidepressant and 224 with a non-SSRI antidepressant. (MEDLINEplus)
Celexa Effective Against Depression with Heart Patients Jan 24, 2007
Explain to interested patients that when depression accompanies coronary artery disease, two SSRI antidepressants, Celexa and Zoloft, now show evidence of efficacy ... One previous trial showed that the SSRI antidepressant Zoloft (sertraline) was effective in this population. (MedPage Today)
