A Woman with Respiratory Failure and a Cavitary Lesion in the Lung Apr 28, 2009
From the Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital (M.E.W.); the Departments of Radiology (G.F.A.) and Pathology (A.F.K.), Massachusetts General Hospital; and the Departments of Medicine (M.E.W.), Radiology (G.F.A.), and Pathology (A.F.K.), Harvard Medical School all in Boston. . (New England Journal of Medicine)
Painkillers May Not Protect Against Dementia Apr 28, 2009
Dr. Steven Vlad, an epidemiology and rheumatology researcher at Boston University School of Medicine, said the findings are "very much contrary to what a number of other studies have found, and I'm not sure how to fit them into previous research.". In the big picture, he said, "the practical, day-to-day utility of this study is small. We just don't know enough yet.". (MEDLINEplus)
Advanced search Apr 17, 2009
Nature Reviews Rheumatology. Nature Reviews Urology. (Nature News Service)
Pharmacyclics Initiates Phase 1 Clinical Trial of Novel Oral Btk Inhibitor for Refractory B-cell Non-Hodgkin's Lymphoma Apr 14, 2009
"This is a very selective compound for B-cells, and it could represent an important alternative to rituximab therapy for the treatment of B-cell NHL. Other obvious applications include autoimmune disorders such as rheumatoid arthritis and lupus, and Pharmacyclics also has strong preclinical efficacy with PCI-32765 in these disease models," said Dr. Mark Genovese, Professor of Medicine and Co-Chief of the Division of Immunology and Rheumatology at Stanford University Medical Center and member of... (PR Newswire)
Birth Control Pills Linked to Lupus Risk Apr 11, 2009
Dr. Bevra Hahn, chief of rheumatology and arthritis at the David Geffen School of Medicine at the University of California, Los Angeles, thinks the new study can be helpful in prescribing oral contraceptives. "The higher the dose of estradiol in women who have been started on oral contraceptives in the past three months, the higher the risk for developing" lupus, Hahn said. (MEDLINEplus)
Nature Reviews Rheumatology (formerly Nature Clinical Practice Rheumatology) Apr 1, 2009
Home : Nature Reviews Rheumatology ... Nature Reviews Rheumatology ... Nature Reviews Rheumatology was previously published as Nature Clinical Practice Rheumatology. (Nature News Service)
Diagnosis of Fibromyalgia Apr 1, 2009
Although fibromyalgia is a complex illness, the diagnostic criteria as per the American College of Rheumatology are quite simple - on paper. There has to be chronic pain in both sides of the body, above and below the waist and in the axial skeleton, such as the spine. (Suite101.com)
To Fight Drug Addiction, Researchers Target The Brain With Nanoparticles Mar 26, 2009
D., professor in the UB departments of Medicine, Pediatrics and Microbiology, director of the Division of Allergy, Immunology and Rheumatology in the UB School of Medicine and Biomedical Sciences, and a co-author on the study. The PNAS paper describes the development of an innovative way to silence DARPP-32, a brain protein, understood to be a central "trigger" for the cascade of signals that occurs in drug addiction. (Science Daily)
Immune cells from patients with rheumatoid arthritis have prematurely aged chromosomes Mar 5, 2009
Fujii is now an assistant professor of hematology and rheumatology at Tohoku University School of Medicine in Japan. Reference: H. Fujii, L. Shao, I. Colmegna, J. Goronzy and C.M. Weyand. (EurekAlert!)
Act early on rheumatoid arthritis: AIHW Mar 5, 2009
President of the Australian Rheumatology Association, Dr Geoffrey McColl, says medications to reduce inflammation and prevent further joint damage can improve the prospect for those with the condition. "Education to help people self-manage the disease also plays an important role in achieving the best outcome," he said. (Sydney Morning Herald -- Australia)
A worm-and-mouse tale: B cells deserve more respect Feb 27, 2009
D., professor of Medicine in the Division of Allergy/Immunology and Rheumatology at the University of Rochester Medical Center, has found an array of unexpected functions for B cells. In the laboratory, she has found that B cells produce chemical signaling molecules known as cytokines that spur other immune cells in the body to action. (EurekAlert!)
Savient Pharmaceuticals Reports Fourth Quarter and Year-End 2008 Financial Results Feb 26, 2009
Savient Pharmaceuticals, Inc. is a biopharmaceutical company engaged in developing and distributing pharmaceutical products that target unmet medical needs focusing in rheumatology and other niche markets. The company's product development candidate, KRYSTEXXA(TM) (pegloticase) for treatment-failure gout, has reported positive Phase 1, 2 and 3 clinical data. (PR Newswire)
The Main Causes of Morning Stiffnes... Feb 25, 2009
according to the American College of Rheumatology affects some 3 to 6 million Americans. That translates to 1 in 50, most of them women, who suffer some form of morning stiffness. (Suite101.com)
Uncertainty hangs over glucosamine Feb 24, 2009
"There is still a lot of uncertainty about glucosamine," says Dr. Steven Vlad, a fellow in clinical epidemiology and rheumatology at Boston University School of Medicine. So what is glucosamine. (Florida Today)
Psoriatic Arthritis Treatment of Ustekinumab Effective, Study Suggests Feb 23, 2009
Researchers conducting the study published in The Lancet reported that at week 12 of the study, 42 percent of patients given 63 or 90 mg of the drug at weeks 0, 1, 2 and 3 showed significant improvement in their pain, stiffness and other symptoms defined by the American College of Rheumatology (ACR20) score compared with 14 percent of patients who received placebo at the same time points (P < 0. 001). (Science Daily)
New clues to healing arthritis caused by traumatic injury Feb 23, 2009
D., of Duke Rheumatology and Immunology. Funding came from a grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health. (EurekAlert!)
Rheumatoid Arthritis Drugs Raise Shingles Risk Feb 19, 2009
"We've changed people's lives with use of these anti-tumor necrosis factor drugs. People who were housebound are now leading relatively normal lives," said Dr. Guy Fiocco, an assistant professor of internal medicine at Texas Ath Science Center College of Medicine and director of rheumatology at Scott in Temple. "This modest increase in risk is not going to stop us prescribing the drug. It may make us more aware.". (MEDLINEplus)
Staying put: Keeping docs in NY a medical community priority Feb 16, 2009
But the main reason Lopez stayed was that his wife, Dr. Aixa Lopez, has a fellowship in rheumatology at. While most of the couple s family is in their native Puerto Rico, Aixa s aunt and uncle are here. (Albany Business Review, NY)
Psoriatic Arthritis Improves with Investigational Biologic Feb 15, 2009
Personalize Your Medical News. Sunday, February 15, 2009. (MedPage Today)
FDA Approves ULORIC(R) (febuxostat) for the Chronic Management of Hyperuricemia in Patients with Gout Feb 14, 2009
The respective companies currently market oral diabetes, insomnia and gastroenterology treatments and seek to bring innovative products to patients through a pipeline that includes compounds in development for diabetes, cardiovascular disease, oncology, gastroenterology, neurology, rheumatology and other conditions. Takeda is committed to striving toward better health for individuals and progress in medicine by developing superior pharmaceutical products. (PR Newswire)
Savient Provides Update on Pegloticase BLA Feb 13, 2009
Savient has exclusively licensed worldwide rights to the technology related to KRYSTEXXA (pegloticase), formerly referred to as Puricase(R), from Duke University and Mountain View Pharmaceuticals, Inc. Savient's experienced management team is committed to advancing its pipeline and expanding its product portfolio by in-licensing late-stage compounds and exploring co-promotion and co-development opportunities that fit the Company's expertise in specialty pharmaceuticals and biopharmaceuticals... (PR Newswire)
A Woman with a Rash and Numbness and Pain in the Legs Feb 12, 2009
Dr. John H. Stone: A 47-year-old woman was seen in the Rheumatology Clinic of this hospital because of numbness and pain in the legs and a rash ... From the Departments of Dermatology (D.K.); Rheumatology, Allergy, and Immunology (J.H.S., D.B.B.); and Pathology (A.S.), Massachusetts General Hospital; and the Departments of Dermatology (D.K.), Medicine (J.H.S., D.B.B.), and Pathology (A.S.), Harvard Medical School. (New England Journal of Medicine)
Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantation Feb 12, 2009
From the Department of Hematology, Oncology, and Transfusion Medicine (G.H., D.N., M.M., S.G., A.M., O.B., I.W.B., W.K.H., E.T.) and the Department of Gastroenterology, Infectious Diseases, and Rheumatology (K.A., T.S.), Campus Benjamin Franklin; and the Institute of Medical Virology, Campus Mitte (J.H.) all at Charit; Universit. tsmedizin Berlin; and the Robert Koch Institute (C.K.) all in Berlin. (New England Journal of Medicine)
The sinking of Blue Peter Feb 11, 2009
He is now Professor of Rheumatology and Tissue Engineering at Bristol University. Last year, he performed an operation that saved the life of a Spanish woman, by giving her a new windpipe made from her own stem cells. (Independent)
FDA Seeks Better Regulation of Painkillers Feb 10, 2009
Also speaking at the press conference, Dr. Bob Rappaport, director of the FDA's division of anesthesia, analgesia, and rheumatology products, underscored the agency's growing concern over the inappropriate use of opiates by citing several alarming statistics. For example, he noted a just released national survey that found that in 2007, 5. (U.S. News & World Report)
authors & referees @ NPG Feb 8, 2009
Nature Clinical Practice Rheumatology. Editor-in-Chief: Peter E. Lipsky, MD; Editor: Jenny Buckland. (Nature News Service)
Drugmakers push boosts murky ailment Feb 8, 2009
Drugmakers respond to skepticism by pointing out that fibromyalgia is recognized by medical societies, including the American College of Rheumatology. I think what were seeing here is just the evolution of greater awareness about a condition that has generally been neglected or poorly managed, said Steve Romano, a Pfizer vice president who oversees its neuroscience division. (MSNBC -- Health)
Abnormal ECG Seen in Psoriatic Arthritis Patients Feb 7, 2009
"In surveying the literature, scant data were found regarding cardiac arrhythmias in psoriatic arthritis patients," researchers note in the Journal of Rheumatology ... SOURCE: Journal of Rheumatology, December 2008. (MEDLINEplus)
Attention to Bones Important in Women with Lupus Feb 7, 2009
"Whether due to the corticosteroid treatment, or to the disease itself, osteoporosis is being increasingly recognized in patients with SLE," Dr. Swan S. Yeap, of the University of Malaya, Kuala Lumpur, and colleagues explain in the Journal of Rheumatology ... SOURCE: Journal of Rheumatology, December 2008. (MEDLINEplus)
Rheumatoid Arthritis Hits Women Harder Feb 7, 2009
"Obvious differences between genders exist in the prevalence, age at onset and level of production of harmful arthritis autoantibodies," study leader Tuulikki Sokka, a rheumatology consultant at Jyv. skyl. (MEDLINEplus)
Lupus Affects the Brain Very Early in the Disease Feb 7, 2009
SOURCE: Journal of Rheumatology, December 2008. Reuters Health. (MEDLINEplus)
Mysterious Fevers Of Unknown Origin: Could Surgery Be A Cure? Mar 30, 2008
He and his colleagues at Children's - including specialists in infectious disease, rheumatology and immunology - plan to pursue these questions further. In the meantime, they hope that increased physician awareness will allow children struggling with this condition to be offered surgery sooner. (Science Daily)
Retired NFL Players At Increased Risk For Heart Problems, Mayo Clinic Finds Mar 29, 2008
14, 2006) People with the skin disorder psoriasis are at increased risk for developing heart disease, according to Mayo Clinic researchers presenting new study data at the American College of Rheumatology. (Nov. (Science Daily)
Fibromyalgia: Chronic pain, chronic questions Mar 26, 2008
Although fibromyalgia is recognized by the American College of Rheumatology and some insurers as a legitimate disease and the U.S. Food and Drug Administration has approved a drug to specifically treat the condition, many people, including medical experts, still doubt its existence. Skeptics say the symptoms are too varied and vague, there's no definitive lab test to prove the disease and most of the people claiming to have fibromyalgia are really suffering from stress, depression and anxiety. (San Diego Union-Tribune)
Controversy Has Patients Fighting To Get Drugs They Need Mar 26, 2008
Yet doctors like Philip Mease with Seattles Rheumatology Associates say he cant always prescribe it. We are being asked to use other medicines that may not be as effective or may have problematic side effects first, said Mease. (KIRO TV, WA)
Britain's best hospitals: A patients' guide Mar 20, 2008
Specialist clinics deal with bone tumours, scoliosis (curvature of the spine), rheumatology, spinal injuries, specialist hand and shoulder conditions and sports injuries. One word of warning the RNOH's trust did not do well in the Healthcare Commission annual health check. (Independent)
Botox for newborns Mar 18, 2008
The Montreal Childrens Hospital provides a high level and broad scope of health care services, and provides ultra specialized care in many fields including: cardiology and cardiac surgery; neurology and neurosurgery, traumatology; genetic research; psychiatry and child development and musculoskeletal conditions, including orthopedics and rheumatology. Fully bilingual and multicultural, the institution respectfully serves an increasingly diverse community in more than 50 languages. (EurekAlert!)
Gene 'linked to higher gout risk' Mar 10, 2008
" At the moment, drug treatment for patients is limited. Although gout is a disease more usually found in a historical textbook, it is estimated that one million people in the UK suffer from it in some form. Professor Stuart Ralston, from the British Society for Rheumatology, said that he often came across patients whose lifestyles did not fit the traditional view of over-consumption. "Until recently you would associate gout with boozing and rich food, but there are plenty of other patients who... (BBC News -- UK)
No docs around, who will cure Uttar Pradesh hospitals? Mar 10, 2008
The departments of Thoracic o-vascular Surgery, Geriatric Medicines, and Rheumatology have a single doctor each. All have to shut down whenever these doctors are on leave. (Expressindia.com)
RA Drugs May Cut Cardiovascular Risk Mar 7, 2008
Personalize Your Medical News. PUTTING BREAKING MEDICAL NEWS INTO PRACTICE Friday, March 07, 2008. (MedPage Today)
Systemic Lupus Erythematosus Feb 28, 2008
From the Centre for Rheumatology Research, Division of Medicine, University College London, London. Address reprint requests to Dr. Isenberg at the Centre for Rheumatology Research, Division of Medicine, University College London, Rm. (New England Journal of Medicine)
Three physicians celebrate first year at St. John Hospital Feb 27, 2008
Prashanth Sunkureddi, M.D. is board-certified in rheumatology and internal medicine, and came highly recommended to St. John Hospital while in fellowship training ... He completed both his internal medicine residency and rheumatology fellowship at UTMB in Galveston ... Dr. Sunkureddi is also a Clinical Assistant Professor of Medicine at UTMB where he is actively involved in the rheumatology fellowship training program. (The Citizen - online, TX)
A Woman with Renal Failure and Stiffness of the Joints and Skin Feb 21, 2008
Dr. Nancy Cibotti-Granof (Medicine): A 46-year-old woman with end-stage renal disease was seen by a rheumatology consultant because of stiffness of her joints and skin ... From the Department of Medicine, Division of Rheumatology, Allergy, and Immunology (J.K.), and the Departments of Nephrology (H.B.), Radiology (L.L.A.), and Pathology (A.F.K.), Massachusetts General Hospital; and the Departments of Medicine (J.K., H.B.), Radiology (L.L.A.), and Pathology (A.F.K.), Harvard Medical School. (New England Journal of Medicine)
Lumbar Spinal Stenosis Feb 21, 2008
From the Department of Orthopedic Surgery (J.N.K., M.B.H.) and the Division of Rheumatology, Immunology, and Allergy, Department of Medicine, Brigham and Women's Hospital (J.N.K.); Harvard Medical School (J.N.K., M.B.H.); and Harvard School of Public Health (J.N.K.) all in Boston. Address reprint requests to Dr. Katz at the Center for Orthopedic and Arthritis Outcomes Research, Brigham and Women's Hospital, 75 Francis St., B3, Boston, MA 02115, or at jnkatz@partners. (New England Journal of Medicine)
Stanford researchers ID therapy targets for MS treatment Feb 19, 2008
Others from Stanford who contributed to this study are: graduate student Jordan Price; postdoctoral scholar Shalina Ousman; Dr. William Robinson, an assistant professor of immunology and rheumatology, and Dr. Raymond Sobel, professor of pathology. Related Industry News. (San Jose Business Journal)
Some cases of autism may be traced to the immune system of mothers during pregnancy Feb 12, 2008
While a growing body of research is dedicated to finding distinctions in the immune systems of children with autism, this is one of the first studies to identify immunological factors in mothers that could be linked to autism in the very earliest stages of life, said Judy Van de Water, senior author of the study and professor of rheumatology, allergy and clinical immunology. Our results should lead to more research on the prenatal environment and the onset of autism. (EurekAlert!)
Hospitals hit the big league Feb 4, 2008
Becoming a Foundation Trust will help us to deliver a vast range of improvements over the next five years including expansions to rheumatology and orthopaedic services, the further development of cardiology services and the creation of a centre of excellence for dermatology. Foundation trusts are still part of the NHS but have more financial freedom to develop services best suited to local needs, along with greater involvement from patients and the public in deciding what they want from... (expressandstar.com)
Sharp Rees-Stealy opening new inland clinic Feb 3, 2008
Care will be provided in these areas: allergy, audiology, endocrinology, family medicine, internal medicine, laboratory, nephrology, neurology, obstetrics and gynecology, optometry (including an optical shop), orthopedics, otolaryngology, pediatrics, pulmonary medicine, radiology, rheumatology, general surgery and urology. The doctors include eight primary care specialists, along with the nurse-practitioner, who does obstetrics and gynecological care, Iwansky said. (North County Times)
FDA Issues Health Advisory On Pfizer's Chantix Tablets Feb 2, 2008
"Chantix has proven to be effective in smokers motivated to quit, but patients and health-care professionals need the latest safety information to make an informed decision regarding whether or not to use this product," said Bob Rappaport, director of the FDA's division of anesthesia, analgesia and rheumatology products. Chantix, an oral tablet taken up to twice daily for 12 weeks to help adults stop smoking, was approved in the U.S. in May 2006. (Wall Street Journal)
Quit-Smoking Drug May Raise Suicide Risk Feb 2, 2008
(SOURCES: Feb. 1, 2008, teleconference with Bob Rappaport, M.D., director, and Celia Winchell, M.D., team leader, Division of Anesthesia, Analgesia and Rheumatology Products, Office of Drug Evaluation II, Center for Drug Evaluation and Research, U.S. Food and Drug Administration) ... "We have become increasingly concerned as we have seen a number of compelling cases that truly look as if they are the result of exposure to the drug and not to other causes," Dr. Bob Rappaport, director of the... (Health-Finder)
Sugary Soft Drinks Linked To Increased Risk Of Gout In Men Feb 2, 2008
Gout was diagnosed according to American College of Rheumatology criteria. During 12 years of follow-up, the researchers documented 755 newly diagnosed cases of gout. (Science Daily)
Scan Uncovers Thousands of Copycat Scientific Articles Jan 31, 2008
According to the D;j; vu entry, 55 percent of Simon's text, published in Best Practice & Research Clinical Rheumatology, closely matches that of a paper published a year earlier by U.T. Southwestern rheumatologist Roy Fleischmann in Expert Opinion on Drug Safety. A review by SciAm. (Scientific American)
Partnership announced between Riley and Saint Joseph Jan 30, 2008
Riley already contributes to SJRMC's Pediatric Specialty Clinics, including cardiology, endocrinology and diabetology, gastroenterology, and rheumatology. Other elements of the partnership include new services to SJRMC's Pediatric Specialty Clinics, such as neurology, with selected services potentially being offered through telemedicine technology. (Niles Star, MI)
British journal retracts article by Harvard doctor Jan 30, 2008
Dr. Lee S. Simon's review of treatments for rheumatoid arthritis, which appeared in Best Practice & Research Clinical Rheumatology in 2004, contained substantial portions from a 2003 article on the same topic in Expert Opinion on Drug Safety, the Best Practice journal said. "This paper has been retracted," according to a statement issued by the Best Practice journal. (Boston Globe)
Reformulating children's medicine Jan 28, 2008
A paper by Dr. Lee Simon of Harvard Medical School and Beth Israel Deaconess Medical Center published in 2004 in Best Practices and Research: Clinical Rheumatology was flagged by software programmed to spot duplication. According to the results, the article reviewing the medical literature on drug treatments for rheumatoid arthritis contained about 55 percent of the text in a previously published paper by UT researcher Roy Fleischmann. (Boston Globe)
Call To Action Jan 25, 2008
He chose to practice rheumatology, a field that has made remarkable strides in research and treatment during the past 35 years. California was America for Mortensen for nearly two decades, until a research company lured him to take a look at Wichita. (Wichita Business Journal, KS)
Transplant Patient Thrives Two Years After Stopping Immunosuppressive Drugs Jan 25, 2008
The researchers describe Kowalski's case in a brief report to be published in the Jan. 24 issue of The New England Journal of Medicine on the technique they developed, based on 25 years of research by Samuel Strober, MD, professor of immunology and rheumatology ... Others from Stanford who contributed to this work are: Stephan Busque, MD, associate professor of surgery; Sussan Dejbakhsh-Jones, research associate in immunology and rheumatology; Claudia Benike, research associate in pathology;... (Science Daily)
Significance And Limitations Of New Lupus Gene Expression Research Jan 22, 2008
Mary K.Crow, M.D., associate chief of the division of Rheumatology and director of Rheumatology research at Hospital for Special Surgery in New York, has written an editorial in The New England Journal of Medicine to accompany the papers. One study appears in The New England Journal of Medicine and the other three appear in Nature Genetics, all to be published online on Jan. 20. (Science Daily)
New Batch of Lupus Genes Discovered Jan 22, 2008
(SOURCES: Noel Rose, M.D., director, Johns Hopkins Center for Autoimmune Disease Research, Baltimore; Susan Manzi, M.D., co-director, Lupus Center for Excellence, University of Pittsburgh; Carl Langefeld, M.D., co-director, International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN), and director, Center for Public Health Genomics, Wake Forest University, Winston-Salem, N.C.; Robert Kimberly, principal investigator, SLEGEN, professor, medicine, Division of Clinical Immunology and... (Health-Finder)
NEJM editorial on significance and limitations of new lupus gene expression research Jan 21, 2008
Mary K.Crow, M.D., associate chief of the division of Rheumatology and director of Rheumatology research at Hospital for Special Surgery in New York, has written an editorial in The New England Journal of Medicine to accompany the papers ... Founded in 1863, Hospital for Special Surgery (HSS) is a world leader in orthopedics, rheumatology and rehabilitation ... HSS is nationally ranked as No. 1 in orthopedics, No. 3 in rheumatology by U.S.News Report, and has received Magnet Recognition for... (EurekAlert!)
DNA variations signal lupus risk Jan 21, 2008
Building on this finding we hope to identify those at highest risk of lupus, diagnose the disease earlier and hopefully find a cure, said Robert Kimberly, M.D., a professor of medicine in the UAB Division of Clinical Immunology and Rheumatology and co-author on the new study ... D., an associate professor of medicine in the UAB Division of Clinical Immunology and Rheumatology and co-author on the study. (EurekAlert!)
Popular Osteoporosis Drugs Triple Risk Of Painful Bone Necrosis, Study Finds Jan 16, 2008
Published online by the Journal of Rheumatology, the findings follow a recent U.S. Food and Drug Administration alert about bisphosphonates that highlighted the possibility of severe and sometimes incapacitating bone, joint and/or muscle pain in patients taking the drugs ... "This is particularly important work," said Dr. John Esdaile, professor and head, Rheumatology, UBC and scientific director, Arthritis Research Centre of Canada located at VCHRI's Centre for Hip Health. (Science Daily)
Drug Approved. Is Disease Real? Jan 14, 2008
Despite the controversy, the American College of Rheumatology, the and insurers recognize fibromyalgia as a diagnosable disease. And drug companies are aggressively pursuing fibromyalgia treatments, seeing the potential for a major new market. (New York Times)
New tool advances injury care Jan 8, 2008
About 100 patients from the Black Hills area have undergone the emerging technology of musculoskeletal ultrasound, a diagnostic ultrasound that is proving to be useful in sports medicine, rheumatology, orthopedics and podiatry. (143). (Rapid City Journal, SD)
Sickness bug closes ward at University Hospital Jan 8, 2008
They quickly stopped new patients being admitted to the rheumatology and general ward while they tested the two affected patients and put other patients under observation. Staff on ward two were also ordered not to go into other wards for fear of spreading the virus throughout the hospital. (ic Coventry)
