Celiac Disease: A Diagnosis Often Missed Oct 2, 2009
Diarrhea, abdominal pain, bloating, gas, distention, weight loss, constipation, irritable bowel syndrome, failure to thrive in infancy, vomiting, short stature, iron deficiency with or without anemia, poor performance in school, delayed puberty, infertility, recurrent miscarriage, osteoporosis, vitamin deficiencies, fatigue, tooth discoloration and dental enamel defects, skin disorders, elevated liver enzymes, Down syndrome, Sjogren's syndrome, aphthous ulcers (canker sores), arthritis,... (CBS News -- Health)
Irregular Heartbeat Risk Higher in Women with Type 2 Diabetes Sep 30, 2009
The authors theorize that diabetes may affect the cardiac autonomic nerves in much the same way the disease damages peripheral nerves and causes a condition known as peripheral neuropathy. Not everyone is convinced that cardiac neuropathy is to blame, however. (MEDLINEplus)
Hanover seniors give acupuncture a try Sep 24, 2009
Marilyn Kosianowicz, who gets around on an electric wheelchair, suffers from neuropathy in her leg and has tried acupuncture once before. I m definitely feeling some sensations in my leg from the needles, she said. (Hanover Mariner, MA)
Nurses fight mandatory flu vaccinations Sep 24, 2009
Both Beck and Phillips mentioned another possible scenario based on a number of cases in 1976 the last time there was a Swine Flu outbreak before this past spring s. The vaccine was blamed for 500 cases of Guillain-Barr; syndrome, an acute peripheral neuropathy causing limb weakness and paralysis. It was also blamed for the death of 25 people from severe pulmonary complications. (Hudson Register Star, NY)
Paula's Health Notes: Happy Feet Sep 18, 2009
A condition called neuropathy can deaden the nerves in the feet ... Any diabetic who already has neuropathy also knows, while a pedicure might be what you want most of all, it's not always safe to go to a standard salon. (KLAS-TV.com, NV)
Marsha Coupé: A life-and-death case for universal coverage Sep 13, 2009
He suffers from post-chemo peripheral neuropathy and a speech impediment after having his mouth rebuilt from tissue taken from his stomach. But he is a healthy, optimistic, happy-to-be-alive man: a walking testament to the dedicated professionals working for the NHS. Living proof that universal health care is one of the best ways to be truly alive and free. (Sacramento Bee -- Opinion)
United States Patent and Trademark Office Publishes Stemedica's Patent Application for the Treatment of Diabetic Retinopathy Sep 8, 2009
Participating patients had varying degrees of Diabetic Retinopathy and Diabetic Optic Neuropathy. Patients received neural progenitor cells by retrobulbar injection and mesenchymal stem cells administered intravenously. (PR Newswire)
Support Group Sep 7, 2009
Monday, September 07, 2009. Deadline for submitting is one week prior to publication. (Erie Times-News, PA)
Detecting often undiagnosed pain in people with dementia Sep 3, 2009
Arthritis, diabetic neuropathy, fractures, muscular contractures, bruises, abdominal pain and mouth ulcers are among the list of common ailments that go undetected. It is important for those who live or work with persons with dementia to know how to identify when an elderly person is experiencing painand receive treatment sooner rather than later. (EurekAlert! -- Business News)
Gene 'Fix' in Egg Prevents Inherited Diseases in Monkeys Aug 28, 2009
These include Leber's hereditary optic neuropathy and myoclonic epilepsy with ragged-red fibers, as well as Kearns-Sayre syndrome, which includes symptoms of pigment retinopathy and cardiac disorders, Mitalipov noted. "More importantly, mtDNA mutations are also increasingly implicated in a range of socially recognizable conditions, including Alzheimer's, Parkinson's and Huntington's diseases, obesity, diabetes and cancer," he said. (MEDLINEplus)
Could 'Monkeying' With DNA Prevent Disease? Aug 28, 2009
Some 150 diseases are known to be caused by mutations in mitochondrial DNA. ; mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS); and Leber hereditary optic neuropathy (LHON) are just three of the known inherited diseases caused by mutations in mitochondrial DNA.. Though many of these incurable diseases result from spontaneous mutations in mitochondrial DNA, others are inherited. (ABC News)
Monkeys born from eggs that got DNA swap Aug 27, 2009
These conditions are uncommon and unfamiliar to most people, such as Leber hereditary optic neuropathy. Roughly one person in every 4,000 or 5,000 either has one of these mitochondrial diseases or is at risk for one. (MSNBC -- Health)
Studies show dramatic decline in rheumatoid vasculitis in US veterans Aug 27, 2009
To determine a RV diagnosis, researchers included those patients who had one of the following: arteritis, mononeuritis multiplex (damage to multiple individual nerve fibers), peripheral neuropathy due to connective tissue disease, gangrene, or chronic ulcers. A past study of data from California hospitals also showed hospitalizations for RV declined between 1980 and 2001. (EurekAlert!)
U.S. Sued Over Dropping of Benefits for Disabled Aug 27, 2009
The suit's plaintiffs include Eshetu Meri, 51, of Fairfax, a blind man who escaped from Ethiopia, where he was targeted for advocating democracy; Tasim Mandija, 80, of Philadelphia, a native of Albania who suffers from prostate cancer and neuropathy; and Rouzbeh Aliaghaei, 17, an Iranian who suffers from a rare genetic disorder that resulted in autism, seizures, mental retardation and an enlarged head. He came to the United States in 1998 when his parents escaped political persecution. (Yahoo News -- Disabilities and the Disabled)
ReBuilder Medical Technologies, Inc. Announces First Quarter 2009 is Profitable Aug 26, 2009
Aug. 25 /PRNewswire-FirstCall/ -- ReBuilder Medical Technologies, Inc. (Pink Sheets: RBRM) a provider of electronic treatments for the pain resulting from Peripheral Neuropathy and Peripheral Artery Disease today announced that it has turned the corner and is now reporting profits for the first Quarter of 2009. (Logo: ). (PR Newswire)
Many foot amputations preventable Aug 25, 2009
And loss of sensation in the feet, called neuropathy, makes patients slow to notice even small wounds that rapidly can turn gangrenous. A mere nick while clipping nails, or a blister from an ill-fitting shoe, can begin the march toward amputation and about half of patients who do lose a foot die within five years. (MSNBC -- Health)
Shingles Complications and Treatmen... Aug 23, 2009
Shingles may cause complications, including postherpetic neuropathy (PHN), herpes zoster opthalmicus (affecting the eye), staph infections, or disseminated shingles. People over the age of 50 are particularly at risk for developing a infection. (Suite101.com)
10 biggest sleep problems: How to fix them Aug 22, 2009
Diabetes, arthritis, peripheral neuropathy, anemia, vitamin B deficiency, thyroid disease, and kidney problems can all contribute to restless leg syndrome. Medications that can cause restless leg syndrome as a side effect include antidepressants, antihistamines, and lithium. (Atlanta Journal-Constitution -- Health)
Around the Region (8/16/09) Aug 16, 2009
NEUROPATHY SUPPORT GROUP ... Info: Neuropathy is a condition involving the nerves outside the central nervous system, mainly affecting the arms, legs, hands and feet. (Modesto Bee, CA)
How can I ease peripheral neuropathy pain? Aug 13, 2009
How can I ease peripheral neuropathy pain ... How can I ease peripheral neuropathy pain ... What can be done to alleviate the symptoms of peripheral neuropathy. (CNN -- Health)
NeurogesX Announces New PDUFA Date for Qutenza(TM) New Drug Application Aug 6, 2009
Its initial focus is on chronic peripheral neuropathic pain, including postherpetic neuralgia (PHN), painful HIV-distal sensory polyneuropathy (HIV-DSP) and painful diabetic neuropathy (PDN). NeurogesX' late stage product portfolio is led by its product candidate Qutenza(TM), a dermal patch designed to manage pain associated with peripheral neuropathic pain conditions. (PR Newswire)
UCLA welcomes startup to new incubator space at California NanoSystems Institute Aug 6, 2009
The technology will be used to develop body monitoring systems with specific applications for use by diabetic patients with peripheral neuropathy the loss of sensation in the foot and those with health issues affecting balance who are at high risk of falls. As part of this arrangement, MediSens Wireless has obtained an exclusive license that will provide the University of California with a royalty on the company's products. (EurekAlert! -- Business News)
Will Tarvaris Jackson's injury cost him in Vikings QB race? Aug 2, 2009
Though he was recently given a clean bill of health, he is still suffering from neuropathy, a side effect from chemotherapy that caused pain in his feet and made him unable to plant his feet and gain leverage. "He's so worried about being a quitter," Childress said. (USA Today -- Sports)
Feet failed retired Udeze Aug 1, 2009
The side effects of chemotherapy finally caught up with the former first-rounder with a condition called neuropathy ... The condition, called neuropathy, is one of the side effects of chemotherapy and hit Udeze hard especially considering the top physical conditioning needed to play at a high level in the NFL.. (VikingUpdate.com)
Cancer Survivors Face Tough Road Long After Treatment Ends Aug 1, 2009
Chemotherapy can also cause delayed problems that aren't apparent until months or years later, including peripheral neuropathy (nerve pain or numbness), infertility, organ dysfunction, hearing loss, muscle atrophy and cardiovascular disease. "Chemotherapy is an effective treatment because it's toxic to the cancer cells, but sometimes it does collateral damage," Stein said. (MEDLINEplus)
Udeze retirement official Aug 1, 2009
Kenechi Udeze fought through emotions and neuropathy to participate in offseason workouts after a year-long battle with leukemia, but he was officially placed on the Vikings reserve/retired list before training camp opened ... My brother said, 'For neuropathy (an abnormality of the nerves) to be the only thing that's really slowing you down, you really have a lot to be thankful for. (VikingUpdate.com)
Vikings' Udeze retires Jul 31, 2009
Udeze participated throughout the minicamp, but struggled with neuropathy in his feet, a side effect of chemotherapy ... Udeze participated throughout the minicamp, but struggled with neuropathy in his feet, a side effect of chemotherapy. (Mason City Globe-Gazette, IO)
Udeze retires, ends comeback from leukemia Jul 31, 2009
Udeze participated throughout the minicamp but struggled with neuropathy in his feet, a side effect of chemotherapy. "When it sets in, your feet start getting really numb and really sensitive, and it's really hard to [move], especially at the level that we're at out here," Udeze said then. (ESPN -- Football)
Newsweek: Fighting cancer with humor Jul 31, 2009
Almost three years ago, at age 29, I was diagnosed with stage III colon cancer The chemotherapy treatment that followed left me, among other keepsakes, with neuropathy in my feet, numbness and tingling similar to what advanced diabetes patients experience. One day I walked two blocks barefoot before I noticed my missing sandal. (MSNBC -- Health)
R-Tech Ueno Notifies R&D Items Jul 31, 2009
We intend to develop this compound as a drug indicated for atopic dermatitis, contact dermatitis and psoriasis vulgaris in the dermatological field, and diabetic neuropathy in the neurological field. We plan to report on the development status of each item on the home page of R-Tech Ueno. (PR Newswire)
Scientists Track Impact Of DNA Damage In The Developing Brain Jul 30, 2009
But the last decade brought evidence linking single-strand DNA damage with human diseases, including ataxia with oculomotor apraxia (AOA1) and spinocerebellar ataxia with axonal neuropathy (SCAN1). Both disorders are inherited and are characterized by progressive difficulty with walking and other movement. (Science Daily)
Letters to the editor, July 23 edition Jul 29, 2009
You have peripheral neuropathy. It took three successive nights in the emergency room seeking pain management, followed by three days in-patient before Scott Papparello from Acton Medical asked five or six questions about my symptoms and within 20 seconds was able to accurately diagnose the problem and begin proper treatment. (Acton Beacon, MA)
A new lease on life Jul 25, 2009
Walking problems, including a form of neuropathy, pursued and, I found myself being more sedentary. She had reached a weight of 208 pounds. (Milton Standard Journal, PA)
Prospects of gold Jul 24, 2009
In 2007, he was diagnosed with a rare disease called Leber's hereditary optic neuropathy. Within six months, he lost about 65 percent of his vision. (News & Observer -- Sports)
First Model Motor Nerve System That's Insulated And Organized Like Human Body Jul 23, 2009
The model system will drastically improve understanding of the causes of myelin-related conditions, such as diabetic neuropathy and later, possibly multiple sclerosis (MS) ... MS, diabetic neuropathy, and many conditions that are caused by a loss of myelin, which forms protective insulation around our nerves, can be debilitating and even deadly ... The UCF team plans to use their new model system to explore the origins of diabetic neuropathy. (Science Daily)
On Call Medical Radio - Peripheral Neuropathy (Part 1 of 2) (2) Jul 19, 2009
On Call Medical Radio - Peripheral Neuropathy (Part 1 of 2) ... Their topic is peripheral neuropathy, a term used to describe the symptoms of pain and numbness in the peripheral nervous system. (Sioux Falls Tri-State Neighbor, SD)
Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding DOXIL(R) for Treatment of Advanced Breast Cancer Jul 16, 2009
In patients with multiple myeloma, the most common all-grade ARs greater than 20 percent (VELCADE plus DOXIL vs VELCADE, respectively) included: neutropenia (36 percent vs 22 percent), thrombocytopenia (33 percent vs 28 percent), anemia (25 percent vs 21 percent), fatigue (36 percent vs 28 percent), pyrexia (31 percent vs 22 percent), asthenia (22 percent vs 18 percent), nausea (48 percent vs 40 percent), diarrhea (46 percent vs 39 percent), vomiting (32 percent vs 22 percent), constipation (31... (PR Newswire)
Erythropoietin overrides the triggering effect of DNA platination products in a mouse model of Cisplatin-induced neuropathy Jul 15, 2009
The clinical efficacy and desirable dose escalations of cisplatin are restricted by the accumulation of DNA lesions in dorsal root ganglion (DRG) cells leading to sensory polyneuropathy (PNP) ... A cumulative dose of 16 mg cisplatin/kg resulted in clear electrophysiological signs of neuropathy, which were significantly attenuated by concomitant erythropoietin (cisplatin 32,48 m/s +/- 1,68 m/s; cisplatin + rhEPO 49,66 m/s +/- 1,26 m/s; control 55,01 m/s +/- 1,88 m/s; p < 0,001). (BioMed Central)
Structural Biology Scores With Protein Snapshot Jul 13, 2009
Sanders and his team, who got interested in protein folding because of their work with DAGK, are now pursuing structural studies of misfolded membrane proteins that cause diseases including peripheral neuropathy (Charcot-Marie-Tooth Disease), diabetes insipidus and Alzheimer's disease. "For proteins that misfold because of mutations, we're using NMR tools to understand exactly what the mutations do to the proteins in terms of structure and stability," Sanders said. (Science Daily)
High Stakes: A Call to Legalize Marijuana Jul 13, 2009
I have diabetic neuropathy and fibromialgia. The VA was giving me massive doses of hydrocodone but it reached the point where it just didn't work any more. (CBS News)
Jackson had no intention to deny his black heritage: doctor Jul 9, 2009
" The cause of Jackson's death has been listed as deferred, pending the results of toxicology tests, which typically take around six weeks, and neuropathy tests, which require the brain to have hardened -- a process that takes about two weeks. Part of Jackson's brain remains with the Los Angeles County coroner. Editor: Mu Xuequan Related Stories. (Xinhuanet, China)
No comments posted. Jul 9, 2009
Capsaicin is an agent in many pain medications used to treat arthritis, diabetic neuropathy and headaches among other ailments. But peppers can also be too much of a good thing. (Big Bear Grizzly, CA)
Multimedia Release: British Men Think Talking About Impotence is "Just Not Cricket" Jul 7, 2009
9) Bloomgarden ZT. American Diabetes Association annual meeting, 1999: nephropathy and neuropathy. Diabetes Care 2000; 23(4): 549 - 556. (PR Newswire)
Superfat hits Asia Jul 2, 2009
And diabetic neuropathy may lead to amputation of the lower limbs. For Big Pharma, the so-called Lipid Lowering Agent (LLA) market - the whole business of drugs that lower cholesterol - used to be a booming market ($26 billion in sales in 2008). (Asia Times Online)
Sangamo BioSciences Announces Achievement of Key Milestone in Cell Engineering Agreement With Genentech Jun 29, 2009
The most advanced ZFP Therapeutic(TM) development program is currently in Phase 2 clinical trials for evaluation of safety and clinical effect in patients with diabetic neuropathy and ALS. Sangamo also has a Phase 1 clinical trial to evaluate safety and clinical effect of a ZFP Therapeutic for the treatment of HIV/AIDS. Other therapeutic development programs are focused on cancer, neuropathic pain, nerve regeneration, Parkinson's disease and monogenic diseases. Sangamo has established strategic... (PR Newswire)
Advanced Nerve Cell System Could Help Cure Diabetic Neuropathy, Related Diseases Jun 29, 2009
ScienceDaily (June 29, 2009) Multiple sclerosis, diabetic neuropathy, and other conditions caused by a loss of myelin insulation around nerves can be debilitating and even deadly, but adequate treatments do not yet exist ... Multiple sclerosis (MS), diabetic neuropathy, Guillain-Barr; syndrome, and other demyelinating conditions are caused when nerve signals can't travel their normal path from node to node due to myelin breakdown ... In the peripheral nervous system, where the problems... (Science Daily)
Novo Nordisk Insulin Analogs Have Proven Safety Profiles Jun 29, 2009
g., patients who are fasting, have autonomic neuropathy, are using potassium-lowering drugs, or are taking drugs sensitive to serum potassium level). Do not mix NovoLog(R) Mix 70/30 with any other insulin product. (PR Newswire)
Support groups Jun 29, 2009
- Peripheral neuropathy support group meets third Wednesday of every month except January, February and March, from 3 to 5 p.m., Springhill Retirement Center, 2323 Edinboro Road. Call 866-9355. (Erie Times-News, PA)
WEX Reports Year End Financial Results Jun 27, 2009
- The Company filed a Clinical Trial Application with Health Canada in February 2009 for a trial of TTX in painful chemotherapy-induced peripheral neuropathy (TEC-007). In March 2009, Health Canada issued a No Objection Letter which permits WEX to conduct the trial in Canada. (CCNMatthews Press Releases)
Human Neurodegenerative Disorder Observed In Fruit Flies Jun 26, 2009
Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot%u2013Marie%u2013Tooth neuropathy. Proceedings of the National Academy of Sciences, June 22, 2009. (Science Daily)
Neuropathy Patients, Doctors and Medical Professionals Rally in Sacramento to Demand Access to Lifesaving Medical Treatments Jun 26, 2009
California Assemblymember Mary Hayashi Calls on California Congressional Delegation to Remember Needs of Neuropathy Patients at 3rd Annual "Neuropathy Action Awareness Day" ... June 25 /PRNewswire/ -- As President Obama continues his push for national health care reform, more than 300 neuropathy patients, physicians and medical professionals gathered in Sacramento today to call on Congress to restore access to life-sustaining and lifesaving treatments for neuropathy patients ... At a press... (PR Newswire)
Scripps research scientists observe human neurodegenerative disorder in fruit flies Jun 25, 2009
In addition to Schimmel, the article, "Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human CharcotMarieTooth neuropathy," was authored by Erik Storkebaum, Ricardo Leito-Gonalves, Inge Bosmans, Patrick Van Dijck, Koen Norga, and Patrick Callaertsa of Katholeike Universiteit Leuven, Tinne Ooms, An Jacobs, Vincent Timmerman, and Albena Jordanova of the University of Antwerp, Tanja Godenschwege and Monica Mejia of Florida Atlantic University,... (EurekAlert!)
A generation born with HIV/AIDS defies the odds Jun 24, 2009
Side effects of taking the medications can include gastrointestinal problems, weight gain, neuropathy and other symptoms. "I didn't want to take the medicine," Lane recalled. (CNN -- Health)
Pinal diabetics find pain treatment 'worth a shot' Jun 23, 2009
"With this treatment, that lack of sensation [brought on by neuropathy] eased up - my leg came back to life." ... -- Reporting possible signs of neuropathy ... Diane Iverson of Eloy couldn't flex her thigh muscle or move her leg correctly for nearly a decade after diabetic neuropathy set in. (Casa Grande Valley Newspapers, AZ)
Special health report Red light relief Jun 23, 2009
Chiropractic neurologist Joe DiDuro wraps a patient's foot with a device that treats the patient's diabetic neuropathy with pulsating infrared light ... Over time - or because of high blood fat, high blood pressure or obesity - diabetics develop some type of neuropathy, or nervous system damage characterized by pain in the hands, arms, feet and legs ... A neuropathy treatment around for more than 20 years, pulsed infrared light therapy, was brought to the area six months ago by Dr. Joe DiDuro, a... (Casa Grande Valley Newspapers, AZ)
U.S. Sued Over Dropping of Benefits for Disabled Jun 22, 2009
The suit's plaintiffs include Eshetu Meri, 51, of Fairfax, a blind man who escaped from Ethiopia, where he was targeted for advocating democracy; Tasim Mandija, 80, of Philadelphia, a native of Albania who suffers from prostate cancer and neuropathy; and Rouzbeh Aliaghaei, 17, an Iranian who suffers from a rare genetic disorder that resulted in autism, seizures, mental retardation and an enlarged head. He came to the United States in 1998 when his parents escaped political persecution. (Yahoo News -- Disabilities and the Disabled)
DNA template could explain evolutionary shifts Jun 22, 2009
The researchers noted that finding this mitotic rearrangement of the gene in the mother, who did not have the disorder, of two children with a neuropathy suggests that the mechanism might be considered in genetic counseling about the risk of having another child with the disorder ... The observation of mosaicism for an apparent mitotically generated, FoSTeS/MMBIR-mediated complex PMP22 rearrangement in the unaffected mother of two children with neuropathy suggests this mechanism can have... (EurekAlert!)
What's a Kidney Among Friends? Jun 21, 2009
The diagnosis: IgA neuropathy, a disease occurring when protein settles in the kidneys, causing them to leak blood and protein into the urine. St. John was told there was no treatment. (The Pilot Newspaper)
Study May Redefine How A Chronic Auto-immune Disease Is Diagnosed Jun 19, 2009
ScienceDaily (June 18, 2009) New research from Jefferson Hospital for Neuroscience (JHN) may redefine how Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is diagnosed ... Eduardo De Sousa, M.D., assistant professor of Neurology at Jefferson Medical College of Thomas Jefferson University, and director of the Electrodiagnostic Neuromuscular Lab at JHN, led the study which looked at the number of demyelinating features that are needed to differentiate between CIDP, Amyotrophic lateral... (Science Daily)
Helping to find a cure for diabetes Jun 18, 2009
Scientists as The Joslin center have found that a high percentage of people who have Type 1 diabetes for 50 years or longer have little or no complications such as kidney damage (nephropathy), blindness (retinopathy) and nerve damage (neuropathy). Center staff also want to find out what is keeping these individuals from having kidney, eye and nerve complications. (Williston Daily Herald, ND)
Adult Type 1 Diabetics Have Higher Depression Rates Jun 16, 2009
Diabetes complications were also self-reported and included retinopathy, blindness, neuropathy, diabetes-related amputation, and kidney or pancreas transplantation. The results showed that adults with type 1 diabetes were more than twice as likely as those without diabetes to have depression and almost three times as likely to have a clinically significant score on the BDI-II. Adult type 1 patients were also nearly twice as likely to be on antidepressant medications as nondiabetics (20. (MEDLINEplus)
Heroes in tough times Jun 3, 2009
Jeff, one of 46 million Americans without health insurance, tells Dr. Oz he wouldn't be able to afford his diabetes and neuropathy medications without access to ECHO.. "If this clinic wasn't here, what would you do?" Dr. Oz asks. (CNN)
Pfizer Canada Announces Recipients of Neuropathic Pain Research Awards Program Jun 2, 2009
Eric Troncy, DV, MSc, PhD, DUn Associate Professor in Physiopharmacology Head Quebec Animal Pharmacology Research Group, Faculty of Veterinary Medicine Functional proteomics as an investigational method of neuropathy diagnostic in a rat model of osteoarthritis pain Universit; de Montr;al Dr. Troncy is the youngest full Professor at the Faculty of Veterinary Medicine of Universit; de Montr;al, his areas of research in GREPAQ are metrology of animal pain, in acute and chronic conditions,... (Canada Newswire)
Neurological Disorder In Golden Retriever Dogs Caused By A Mutation In Mitochondrial DNA May 31, 2009
ScienceDaily (May 30, 2009) Sensory ataxic neuropathy (SAN) is a recently identified neurological disorder in Golden Retriever dogs with onset during puppyhood ... derlund KH, Nennesmo I, Holmqvist E, Heidrich N, et al. Sensory Ataxic Neuropathy in Golden Retriever Dogs Is Caused by a Deletion in the Mitochondrial tRNATyr Gene ... Researchers in Sweden have figured out the basis for a neurological disorder in Golden Retriever dogs called sensory ataxic neuropathy. (Science Daily)
Proteolix Presents Phase 1b/2 Clinical Data for Carfilzomib in Advanced Solid Tumor Patients at the 2009 ASCO Annual Meeting May 31, 2009
Notably, there were no incidents of Grade 3/4 neuropathy, a common side effect associated with the approved proteasome inhibitor, bortezomib. To date, 65 patients in the Phase 1b and Phase 2 clinical trials have received 154. (PR Newswire)
