Mercedes's Head-Turning Smart Car Has Metrosexual Appeal in U.S. Market Jul 16, 2008
At times, the engine seems to suffer from narcolepsy. The bigger issue is the transmission, which is so lousy it verges on being a deal breaker. (Bloomberg -- Germany)
Popular Stimulant's Role In Brain Function Deterioration Is Cause For Concern, According To Researchers Jun 18, 2008
Methylphenidate also is occasionally prescribed for treating narcolepsy. Because stimulant medicines such as MP do have potential for abuse, the U.S. Drug Enforcement Administration (DEA) has placed stringent, Schedule II controls on their manufacture, distribution and prescription. (Science Daily)
The Hulk: Big, Green, Sleep-Inducing Jun 13, 2008
You'd think only someone suffering an advanced case of narcolepsy would be immune to them. Not so, as far as I'm concerned. (Time.com)
Diets that eat away at illnesses Jun 12, 2008
The results come as researchers and physicians are seeking ways to leverage the ketogenic diet to treat various other neurological disorders, including ALS, brain tumors, autism, Parkinson s disease, Alzheimer s disease, narcolepsy and migraines. Many of these conditions respond to anticonvulsant medications, said Dr. Eric Kossoff, medical director of the Ketogenic Diet Center at Johns Hopkins Hospital, and the ketogenic diet seems to act as an anticonvulsant. (Racine Journal Times, WI)
More of this story Jun 7, 2008
Stimulants that are prescribed for attention-deficit hyperactivity disorder (ADHD), the sleep disorder narcolepsy or obesity. These drugs go by names such as oxycodone or OxyContin, propoxyphene or Darvon, hydrocodone or Vicodin and hydromorphone or Dilaudid. (Andalusia Star News, AL)
Letters to the Editor (77) Jun 5, 2008
Jules wrote on Jun 4, 2008 1:35 PM:" What a typical lib trick. Worse than push-polling. Abigail creates a fictional concern for PTSD in McCain and then tries to get everyone worried about it. How about this: I worry that Obama may have epilepsy, dropsy, and narcolepsy. I question the ability of a leader to make decisions in a time of crisis while suffering from all three. Of course, there is just as much evidence for epilepsy in Obama as there is for PTSD in McCain, but that won't stop the libs... (Corvallis Gazette Times, OR)
Family faces foreclosure fear Jun 4, 2008
She was suffering from narcolepsy brought on by sleep apnea as well as problems with her feet. He couldn't drive, we couldn't read through all that paperwork and understand it, she said. (Santa Maria Times)
Acupuncture Eases Side Effects of Head, Neck Cancer Treatments Jun 3, 2008
Narcolepsy drug also helped with severe fatigue among patients on chemotherapy ... A second study presented Saturday at the meeting found the narcolepsy drug Provigil (modafinil) provided significant relief for patients suffering from chemotherapy-related fatigue. (MEDLINEplus)
Recession-resistant careers Jun 1, 2008
Part of the burgeoning field of sleep medicine, sleep technologists like Jean help doctors diagnose sleep disorders such as narcolepsy and sleep apnea. Mostly what we re watching is their brain waves going across the [computer] screens, says Jean, 25, a former background investigator at a financial services company. (Boston Globe)
'Food Clock' May Override Master Sleep Clock in Times of Duress May 25, 2008
While equally intrigued, Dr. Emmanuel Mignot, director of the Stanford University Center for Narcolepsy, cautioned that the current research with animals still needs to be replicated in humans. 1. (U.S. News & World Report)
Researchers see flood of "brain-boosting" drugs May 22, 2008
Another is modafinil, the active ingredient in Cephalon's narcolepsy medicine Provigil. "Drug companies are very interested in this area," Les Iverson, a researcher at the University of Oxford who worked on the report, told a news conference. (Scientific American)
Day-to-day struggle May 13, 2008
Because she suffers from the two debilitating diseases, Hughes-Hood takes a nerve-deadening pill, which causes drowsiness; a narcolepsy pill to combat low energy; pain medication; and a sleeping aid at night. "I'm in pain from sunup to sundown," she explained. (The Clarion-Ledger)
New Weapons Against Cocaine Addiction May 7, 2008
Experimental therapies, including one marketed for epileptic seizures and another for the sleep disorder narcolepsy, appear to help addicts quench or diminish the thirst for cocaine. Scientists are also trying to enlist the immune system to thwart cocaine abuse. (Scientific American)
Great New Recreational Drugs for Nerds Apr 11, 2008
Respondents were given : A) "No, I have never taken any of these drugs for any reason." B) "Yes, I have taken one of these drugs for a medically diagnosed condition (e.g. narcolepsy, attention deficit hyperactivity disorder, or hypertension)." C) "Yes, I have taken one of these drugs or other drugs for non-medical reasons to improve my concentration, focus and memory." Thirteen percent answered B. Twenty percent answered A.. You don't have to be a scientist to do the math: The number of people... (Slate)
Enhancing, not cheating Apr 10, 2008
The pills with least risky side effects seem to be methylphenidate (prescribed for attention-deficit disorder) and modafinil (prescribed for narcolepsy). Studies, mostly in the United States, have documented usage of drugs for cognitive enhancement by 5 15% of students, and anecdotes abound of use by postdocs and academics. (Nature News Service)
Eating Disorders Often Accompany Narcolepsy Apr 1, 2008
NEW YORK (Reuters Health) - Many patients with narcolepsy with cataplexy also experience a number of symptoms of eating disorders, according to findings from a Dutch study reported in the journal Sleep. People with narcolepsy suffer from episodes in which they suddenly fall asleep ... Aside from the main features of excessive daytime sleepiness and cataplexy, one of the more prominent symptoms of narcolepsy is an increase in body weight, Dr. Hal A. Droogleever Fortuyn, of Radboud University... (MEDLINEplus)
Got sleep? Red Sox, A's could use some Mar 29, 2008
Narcolepsy -- intermittent, uncontrollable episodes of daytime sleep -- is another disorder which is not only disruptive, it can be dangerous. Lack of sleep has also been linked to obesity and diabetes. (MLB.com -- Boston Red Sox)
Pharming and Generation Rx Mar 26, 2008
Stimulants, which are prescribed to treat the sleep disorder narcolepsy, attention-deficit hyperactivity disorder and obesity. Examples include dextroamphetamine (Dexedrine and Adderall) and methylphenidate (Ritalin). (Wood River Journal, ID)
High Prevalence Of Eating Disorders Found In Narcoleptics Mar 4, 2008
3, 2008) The majority of patients with narcolepsy/cataplexy experience a number of symptoms of eating disorders, with an irresistible craving for food and binge eating as the most prominent features, according to a new study ... The study, authored by Hal Droogleever Fortuyn, MD, and Sebastiaan Overeem, MD, of the Radboud University Nijmegen Medical Center in The Netherlands, focused on 60 patients with narcolepsy/cataplexy who were recruited from specialized sleep centers and 120 healthy... (Science Daily)
New study in the journal SLEEP finds a high prevalence of eating disorders in narcoleptics Mar 2, 2008
The majority of patients with narcolepsy/cataplexy experience a number of symptoms of eating disorders, with an irresistible craving for food and binge eating as the most prominent features, according to a study published in the March 1 issue of the journal SLEEP.. The study, authored by Hal Droogleever Fortuyn, MD, and Sebastiaan Overeem, MD, of the Radboud University Nijmegen Medical Center in The Netherlands, focused on 60 patients with narcolepsy/cataplexy who were recruited from specialized... (EurekAlert!)
Journal SLEEP: Methylphenidate can have sleep benefits in adults with ADHD Mar 2, 2008
MPH is a prescription stimulant commonly used to treat ADHD. It is also one of the primary drugs used to treat the daytime drowsiness symptoms of narcolepsy and chronic fatigue syndrome. A medication can provide much needed relief for someone with a severe sleep problem. (EurekAlert!)
Harvard doctor joins Rutherford County Sleep Center Mar 1, 2008
Sleep medicine specialists diagnose and treat sleep disorders like snoring and sleep apnea, narcolepsy, insomnia, and conditions such as sleepwalking, sleep talking and night terrors. Related Industry News. (Nashville Business Journal, TN)
JON LEIBOWITZ: How collusion keeps generic drugs off shelf Feb 28, 2008
The agency filed suit this month against Cephalon, which manufactures Provigil, a product that helps those with sleep apnea and narcolepsy. In 2003, four of Cephalon's competitors tried to enter the Provigil market -- which generated $800 million in sales last year -- by offering a low-cost generic version. (Fresno Bee -- Opinion)
Daytime Dozing May be Indicator of Future Stroke Feb 24, 2008
Sounds more like narcolepsy than dozing off ... Narcolepsy is falling into a deep sleep while dozing can be as short as seconds. (MedHeadlines)
New Sleep Diagnostic Center Opens at Methodist Mansfield Feb 22, 2008
The new center provides two specially designed sleep-study suites to evaluate sleep apnea, insomnia, restless leg syndrome, narcolepsy, snoring, sleepwalking, and other sleep difficulties ... His sleep training includes obstructive sleep apnea, central sleep apnea, restless leg syndrome, insomnia and narcolepsy. (PR Newswire)
Changes In Narcoleptics' Skin, Core Body Temperatures Affect Their Vigilance And Sleepiness Feb 6, 2008
Among those suffering from narcolepsy, however, direct manipulations of their skin and core body temperatures affect their vigilance and sleepiness, according to a new study ... The study, authored by Rolf Fronczek, of the Netherlands Institute for Neuroscience in Amsterdam, and Leiden University Medical Center in The Netherlands, focused on eight patients who were diagnosed with narcolepsy with cataplexy and suffered from excessive daytime sleepiness ... According to the results, patients were... (Science Daily)
Sleep disorders: Don't take it lying down Jan 29, 2008
Stimulants and antidepressants can treat narcolepsy daytime sleep attacks. Hypnotics like zopiclone or benzodiazepines can be prescribed for less than a fortnight to treat severe insomnia. (Independent)
Different Neural Pathways at Work Going under, Coming out of Anesthesia Jan 23, 2008
They found that mice with damaged orexin systems -- similar to humans with narcolepsy -- took much longer to awake from general anesthesia than mice with normal orexin signaling systems. However, the mice with faulty orexin systems did not fall asleep faster than normal mice when given a general anesthetic. (MEDLINEplus)
more » Jan 22, 2008
We deal with sleep apnea, narcolepsy, which requires daytime tests, restless leg syndrome and REM-related disorders. Sleep involving rapid eye movements REM is divided into three stages and is the most important part of sleep, Davis said. (Searcy Daily Citizen, AR)
Ship pilot's health scrutinized Jan 19, 2008
Modafinil, often sold under the brand name Provigil, is given to people with narcolepsy, sleep apnea, and other similar disorders to help them stay awake. Cota was also taking another prescription drug, apparently to treat anxiety, that person and a federal official said. (Boston Globe)
Rest covered from A to Zzz's Jan 18, 2008
Or it could be falling asleep suddenly during waking hours, called narcolepsy. And dysfunction in those activities could have links to heart disease, high blood pressure and metabolic disorders that could manifest themselves in diabetes and hypoglycemia, not to mention the traffic and industrial accidents resulting from poor concentration induced by poor sleep. (Daytona Beach News Journal)
2 different neural pathways regulate loss and regain of consciousness during general anesthesia Jan 12, 2008
Studying mice whose orexin systems had been genetically destroyed a state similar to humans suffering from narcolepsy, a neurological condition that causes unusual daytime sleepiness Max B. Kelz, MD, PhD, an assistant professor in Penns Department of Anesthesiology and Critical Care and the Mahoney Institute of Neurological Sciences, found that these mice took much longer to emerge from general anesthesia than those with normal orexin signaling systems. However, the mice with faulty orexin... (EurekAlert!)
Sleep Center aids the area’s restless Jan 8, 2008
Narcolepsy is an overwhelming, daytime sleepiness. The Sleep Center utilizes all-night sleep studies, monitoring physiological responses throughout the course of a rest period, even shift workers who sleep during the day. (Rolla Daily News, MO)
Protein Nasal Spray Revives Sleep-Deprived Monkeys Jan 8, 2008
A natural brain compound could help shift workers or those with narcolepsy, scientists say ... The researchers suggested that these results could have important implications for people suffering from the sleep disorder narcolepsy and for people whose lifestyles may cause sleep deprivation, such as shift workers. (MEDLINEplus)
Researchers Reverse Effects Of Sleep Deprivation Jan 4, 2008
"This could benefit patients suffering from narcolepsy and other serious sleep disorders. But it also has applicability to shift workers, the military and many other occupations where sleep is often limited, yet cognitive demand remains high.". Orexin-A, also known as hypocretin-1, is a naturally occurring peptide produced in the brain that regulates sleep. (Science Daily)
Baylor University Scientists Develop Cocaine Vaccine Jan 3, 2008
Researchers have developed a partly funded by DARPA. The medication is being looked at to help keep troops alert and will likely be used to treat the sleep disorder narcolepsy if it gets FDA approval. Comments. (DailyTech)
Nasal Spray Might Replace Sleep Dec 29, 2007
The discovery's first application will probably be in treatment of the severe sleep disorder narcolepsy. The treatment is "a totally new route for increasing arousal, and the new study shows it to be relatively benign," said Jerome Siegel, a professor of psychiatry at UCLA and a co-author of the paper. (ABC News)
From Shooting Pain To Shiver, Role Of Gatekeeper Protein In Sensing Cold Confirmed Dec 26, 2007
25, 2007) For the first time, neuroscientists have visualized cold fibers -- strands reaching from sensory neurons near the spinal cord to nerve endings in the skin tuned to sense different types of cold. Surprisingly, given the highly diversified sensory system and the range of sensations studied -- harmless cool, stinging cold, soothing coolness -- the fibers lead back to one place in the neuron: a protein known as TRPM8 that relays a cold signal up the spinal cord to the brain. (Science Daily)
News tips from the Journal of Neuroscience Dec 26, 2007
The loss of the hypothalamic neurons that produce orexin-A causes narcolepsy, and the administration of orexin-A produces arousal and increased attention. This week, Deadwyler et al. provide further evidence that orexin-A can counteract the effects of sleep deprivation. (EurekAlert!)
Vancouver anti-gang unit says tactics are working Dec 22, 2007
Body armour and tank-like SUVs seized in B.C. gang sweep. Body armour and tank-like SUVs seized in B.C. gang sweep. (CBC British Columbia)
1st Kuwaiti woman MP sworn in Dec 22, 2007
Health Canada has issued a warning about serious skin and allergic reactions related to Alertec, a drug used to relieve excessive sleepiness due to narcolepsy, obstructive sleep apnea and shift-work sleep disorders. U.S. health officials say improper use of patches that emit the painkiller fentanyl is still killing people. (Yahoo News -- Kuwait)
Apologies too little, too lame, too late Dec 20, 2007
We weren't spared the "it was the Jack Daniels ... flaxseed oil ... sex with my wife ... narcolepsy ... ginseng tea ... B-12 shot" part of the program. The routine looked a little different this time. (San Francisco Chronicle -- Sports)
Drugs to build up that mental muscle Dec 20, 2007
"There isn't any question about it -- they made me a much better player," said Paul Phillips, 35, who credited the attention deficit drug Adderall and the narcolepsy pill Provigil with helping him earn more than $2. 3 million as a poker player. (Los Angeles Times)
Sleepless in December Dec 15, 2007
MIAMI Between 50 million and 70 million Americans have some sort of sleep disorder, be it apnea, insomnia, narcolepsy ... suffers from narcolepsy, a disorder causing daytime sleepiness ... One in 2,000 suffer from narcolepsy, a neurological disorder causing people to fall asleep throughout the day, according to the National Sleep Foundation. (Herald Online, SC -- Health)
Practice parameters discuss treatment for narcolepsy, other hypersomnias of central origin Dec 2, 2007
Practice parameters published in the December 1 issue of the journal SLEEP serve as both an update of previous practice parameters for the therapy of narcolepsy and as the first practice parameters to address treatment of other hypersomnias of central origin, including idiopathic hypersomnia, recurrent hypersomnia and hypersomnia due to medical condition ... The following are highlights of recommendations for the treatment of narcolepsy and other hypersomnias of central origin ... Modafinil is... (EurekAlert!)
Sleep medicine 'can help ice addicts quit' Dec 2, 2007
He says Modafinil is normally used to treat sleeping problems like narcolepsy or shift work sleep disorder, and acts on the same parts of the brain as ice does. "Modafinil actually works in those parts of the brain to kind of restore areas of those neurotransmitters," he said. (ABC Online)
Hospital opens sleep disorder center Nov 30, 2007
The gathered data can then be used to diagnose different types of sleep disorders, including sleep apnea (the obstruction of the airway during sleep, causing loud snoring and sudden awakenings when breathing stops); narcolepsy (the condition of falling asleep spontaneously and unwillingly at inappropriate times); restless legs syndrome (an irresistible urge to move legs); REM behavior disorder (acting out violent or dramatic dreams while in REM sleep); and parasomnias (include a variety of... (Jakarta Post, Indonesia -- City)
Reasons women arent backing Hillary Nov 22, 2007
Reasons women arent backing Hillary - Melrose, MA - Melrose Free Press. Reasons women arent backing Hillary. (Melrose Free Press, MA)
Hormone links hunger, sleep Nov 17, 2007
Research conducted by UT Southwestern found that a lack of orexin is the cause of narcolepsy ... "If you can find a drug that substitutes for orexin, the strong prediction is that you can cure narcolepsy. Our results just emphasize this point." Page 1 of 1. (The Daily Texan, TX)
The BALCO investigation Nov 16, 2007
BALCO investigation timeline - USATODAY.com. Buy and sell tickets to premium and sold out events. (USA Today -- Sports)
Hormone Links Sleep, Hunger And Metabolism Nov 15, 2007
Researchers, including Dr. Masashi Yanagisawa, professor of molecular genetics at UT Southwestern, had found that lack of orexin causes the sleep disorder narcolepsy ... "You lack orexin" You've got narcolepsy. (Science Daily)
Cephalon settles drug marketing probe for $425M Nov 11, 2007
The probe was believed to be looking at whether company sales representatives were improperly marketing Cephalon's flagship drug Provigil, which is approved for narcolepsy and other sleep disorders, although physicians have prescribed the drug for other conditions, such as depression and attention deficit hyperactivity disorder. In February, the FDA sent Cephalon a warning letter ordering the company to discontinue promotional material for Provigil that included claims that the drug could be... (Philadelphia Business Journal, PA)
Cephalon settles marketing probe, raises earnings forecast Nov 10, 2007
Cephalon was being investigated for off-label sales and marketing practices of its drugs epilepsy drug Gabitril, narcolepsy drug Provigil and cancer pain reliever Actiq. Doctors can prescribe drugs for uses other than what s been approved by the U.S. Food and Drug Administration, but drug companies cannot promote such off-label marketing. (Somerset Daily American, PA)
Peek at the Week: The teams nobody can beat meet Nov 3, 2007
Welcome to the Narcolepsy Bowl. Atlanta is 30th in scoring; the 49ers are 31st. (CBS News)
The Prado gracefully revolutionizes its space Nov 1, 2007
Years of Spanish isolation, neglect under Franco, then institutional incompetence, compounded the impression of narcolepsy. Melancholy reports of leaks in the ceiling, or yet another director promising change before evaporating, overshadowed the odd loan exhibition. (International Herald Tribune -- Arts)
Britney and K-Fed battle it out again in court Oct 30, 2007
What about the narcolepsy situation. They found pills in her purse or pictures of pills, and now she has narcolepsy and she is driving ... BERNIE GRIMM, CRIMINAL DEFENSE ATTORNEY: She has narcolepsy and she is driving. (Fox News)
Provigil drug gets new warning on label Oct 26, 2007
Provigil is OK'd by the FDA as a treatment for narcolepsy and other disorders where excessive sleepiness is a symptom. As part of the new label, Cephalon (NASDAQ:CEPH) advised patients to stop using the drug and get medical attention if they develop a skin rash. (Philadelphia Business Journal, PA)
Remote Heat Imaging Identifies Sleep Disorder Without Disturbing Patients Oct 26, 2007
16, 2007) Modafinil is well-tolerated in the treatment of excessive sleepiness associated with disorders of sleep and wakefulness such as shift work sleep disorder, obstructive sleep apnea and narcolepsy, and. . (Science Daily)
From faithful dogs and difficult fish, insight into narcolepsy Oct 25, 2007
Bear had spent nearly seven years in the underground kennels as part of a colony of narcoleptic dogs studied by Dr. Emmanuel Mignot, director of the Stanford Center for Narcolepsy ... Bear's freedom ended 30 years of investigations that led to the discovery of the importance of a neurochemical called hypocretin in human and animal narcolepsy, and in normal sleep ... Investigators now understand that narcolepsy arises from a deficiency of the brain cells that make hypocretin, similar to the way... (International Herald Tribune -- Health)
FDA Warns on Cephalon's Provigil Oct 25, 2007
Provigil is indicated to improve wakefulness in adult with narcolepsy, obstructive sleep apnea/hypopnea syndrome and shift-work sleep disorder. The FDA warned that there have been rare cases of serious or life-threatening rashes, angiodema and multi-organ hypersensitivity reactions and also psychiatric side effects such as anxiety, mania, hallucinations and suicidal ideation. (TheStreet.com)
Is A Good Night's Sleep Crucial For Your Health? Oct 25, 2007
The group in Munich and Ingolstadt has first evidence for an influence of a chronic sleep disorder going along with severe sleepiness (narcolepsy) on the processing of emotional stimuli in the brain, suggesting that disturbed sleep regulation profoundly interferes with our well being and the interaction with the environment. Basic research in the human sleep research laboratory of the University of Z. (Science Daily)
Lack of sleep linked to emotional imbalance, imaging study suggests Oct 24, 2007
Sleep disorders include insomnia, sleep apnea, restless leg syndrome and narcolepsy. Parasomnias - including nightmares, night terrors and sleepwalking - also can disrupt sleep. (San Francisco Chronicle)
Modafinil Is Effective In Treating Excessive Sleepiness, Study Suggests Oct 17, 2007
A study published in the October 15 issue of the Journal of Clinical Sleep Medicine finds that modafinil is well-tolerated in the treatment of excessive sleepiness associated with disorders of sleep and wakefulness such as shift work sleep disorder, obstructive sleep apnea (OSA) and narcolepsy, and does not affect cardiovascular or sleep parameters ... In the narcolepsy studies one patient in the modafinil group and one in the placebo group had a clinically significant increase in heart rate ...... (Science Daily)
Fish Get Insomnia, Eyes Wide Open, Say Sleep Researchers Oct 17, 2007
The work represents a milestone in sleep research by Emmanuel Mignot, MD, PhD, who also uncovered the genetic cause of narcolepsy in dogs ... Mignot's laboratory found the gene responsible for narcolepsy in Dobermans and Labradors in 1999, helping reveal how the disorder occurs in humans ... Narcolepsy affects about one in 2,000 people, with few recognizing their sleepiness as a medical problem. (Science Daily)
Cycling: Franck Bouyer nears victory in bid to stay awake Oct 17, 2007
" Unless, that is, somebody is asleep at the switch. Often, that has been Bouyer. Today in Sports The 33-year-old Frenchman has narcolepsy, a disorder marked by recurring and unpredictable episodes of sleep during normal waking hours and disturbed sleep at night. He was diagnosed with the genetic disease, which is believed to afflict one person in 200,000, late in 2003 and since then his life has been, as he says without irony, a nightmare. It's not just that he tosses and turns while trying to... (International Herald Tribune -- Sports)
