Govs want North to develop own goods, economy Nov 7, 2008
In his opening address, the Chairman of the Northern Governors' Forum (NGF), the Governor of Niger State, Dr. Muazu Babangida Aliyu said: "Indeed, I must repeat that it is time we took our destinies in our hands and develop our agricultural and livestock sectors as the backbone of our economic survival, which we should consider as our comparative advantage." ... The NGF chairman stressed further that some of the federal agencies which the North needed to tap into were those of the Central Bank... (Guardian News, Nigeria)
Prenatal drinking, environmental enrichment: effects on neurotrophins are independent of each other Jul 19, 2008
"Neurotrophins also play important roles in learning and memory, and contribute to the repair of the brain following injury or stress. We chose to examine three nerve growth factor (NGF), neurotrophin-3 (NT-3), and brain-derived neurotrophic factor (BDNF) because previous research had shown that prenatal alcohol exposure alters their levels in the brain, and that treatment of other types of brain injury with NGF or BDNF can be beneficial." ... Levels of NGF, NT-3 and BDNF were then measured... (EurekAlert!)
Limitations in assessing nerve growth factor levels in aqueous humor samples from human eyes Jun 6, 2008
Nerve growth factor (NGF) helps in the healing and survival of ganglion cells, photoreceptors, and optic nerve after injury and has been implicated to have a role in pathophysiology of glaucoma. So far, in animal studies, injury to iris in vitro has revealed an increase in NGF levels in aqueous ... There is a great interest in investigating the levels of NGF in human aqueous in glaucomatous eyes, as suggested by animal studies, to gain a better understanding of the pathophysiology of glaucoma. (BioMed Central)
Killer competition: Neurons duke it out for survival May 7, 2008
Target tissues innervated by so-called peripheral neurons coax nerves to grow toward them by releasing nerve growth factor protein, or NGF. Once the nerve reaches its target, NGF changes from a growth cue to a survival factor. In fact, when some populations of nerve cells are deprived of NGF they die ... To further investigate how this NGF-dependent survival effect works the researchers looked for genes that are turned on by NGF in developing nerve cells. (EurekAlert!)
Family Of Liver Cancer Genes Discovered Mar 1, 2008
19, 2007) Nerve growth factor (NGF), as the name says, is an essential peptide factor for the growth and differentiation of neuronal cells. Therefore we can imagine that this growth factor is important for the. (Science Daily)
Scientists Shed Light On Long-distance Signaling In Developing Neurons Feb 23, 2008
In recent years, scientists discovered that as the axon reaches its target which may be many centimeters away from the nucleus it senses a signal called nerve growth factor (NGF), which is made by target tissues ... "But the axons that correctly navigate to their destinations detect NGF which 'says' to the neuron 'No, you've made it, you can survive.' In these rarer cases, the neuron lives to become part of the nervous system." ... The team next used cutting-edge fluorescent technology to track... (Science Daily)
Sex chemistry 'lasts two years' Feb 11, 2008
Similar research conducted by Enzo Emanuele at the University of Pavia found that levels of a chemical messenger called nerve growth factor (NGF) increased with romantic intensity. After one to two years, NGF levels had reduced to normal. (BBC News)
Proteomic Profiling Shown More Accurate Than Traditional Biomarkers In Identifying Liver Cancer Jan 17, 2008
16, 2008) As the incidence of liver cancer continues to grow-- fueled in large part, by rising rates of hepatitis C infections -- so too does the need for tests to help diagnose the disease at an earlier stage. A study appearing in the January 15 issue of Clinical Cancer Research demonstrates that a novel mass-spectrometry based form of proteomic profiling is more accurate than traditional biomarkers in distinguishing liver cancer patients from patients with hepatitis C liver cirrhosis,... (Science Daily)
Gene Variation May Elevate Risk Of Liver Tumor In Patients With Cirrhosis Jan 3, 2008
19, 2007) Nerve growth factor (NGF), as the name says, is an essential peptide factor for the growth and differentiation of neuronal cells ... 11, 2007) Biologists have published a surprising discovery that NGF and its receptor were aberrantly expressed in the liver of the patients troubled with liver cirrhosis and/or hepatocellular carcinoma (HCC). (Science Daily)
Mutation May Cause Inherited Neuropathy Dec 29, 2007
25, 1998) Implants to deliver nerve growth factor (NGF) to nerve cells in the brain were described here today (Aug ... 3, 1997) For the first time, scientists have shown through genetic studies in adult mice that depletion of the protein nerve growth factor (NGF) causes a decline in learning and memory, mimicking a major. (Science Daily)
Natural protein 'heals the heart' Nov 18, 2007
Nerve growth factor (NGF) was thought to act only on nerve cells in the body, but mounting evidence suggests it acts on heart muscle cells too. A Bristol Heart Institute team tested NGF in rats and this had promising results, Cell Death and Differentiation journal reports ... Dr Costanza Emanueli and her colleagues found that injecting the gene for NGF into the hearts of rats having a heart attack stopped heart cells dying off. (BBC News -- UK)
Chemical Compound Found In Tree Bark Stimulates Growth, Survival Of Brain Cells Oct 6, 2007
The tree bark compound, known as gambogic amide, behaves much like Nerve Growth Factor (NGF), a molecule found in the brain. NGF binds to TrkA, a neuronal receptor, and activates neuronal signaling ... "Humans actually have a naturally occurring molecule in the body, Nerve Growth Factor (NGF), which stimulates the growth and differentiation of certain types of nerve cells. However, NGF has poor pharmocokinetics and bioavailability when synthetically manufactured and used therapeutically, and it... (Science Daily)
Natural Protein Could Help Spot, Treat Liver Cancer Sep 20, 2007
WEDNESDAY, Sept. 19 (HealthDay News) -- A natural protein called nerve growth factor (NGF) may prove an effective target for the treatment of liver cancer, Italian researchers say. NGF is an essential component in the growth and differentiation of neuronal cells, explained the team, who reported their findings in the Oct. 7 issue of the World Journal of Gastroenterology ... This study found that NGF also appears to be a factor in liver cancer, one of the leading causes of cancer death worldwide.... (Health-Finder)
Targeting Nerve Growth Factor May Cure Liver Cancer, Study Suggests Sep 11, 2007
Nerve growth factor (NGF), as the name says, is an essential peptide factor for the growth and differentiation of neuronal cells ... But a recent scientific report published in the October 7 issue of the World Journal of Gastroenterology tells us another surprising and exciting discovery about this growth factor: NGF is positively related with liver cancer, the No.2 killer among all kinds of cancers in the world ... With many beautiful pictures of immunohistology, these scientists showed that... (Science Daily)
MediciNova Announces First Quarter 2007 Financial Results May 11, 2007
MN-166 inhibits leukotriene activity, phosphodiesterase 4, 10, 11 and glial nitric oxide synthesis, all inflammatory mechanisms known to be involved in MS. MN-166 may also suppress the production of pro-inflammatory cytokines (IL-1beta, TNF-alpha, IFN-gamma, IL-6) and may enhance the production of the anti-inflammatory cytokines (IL-4, IL-10) and neurotrophic factors (NGF, GDNF, NT-4). Recently, MN-166 was found to have positive effects in the first year of a two-year randomized, double-blind,... (Primezone Releases)
Raptor Pharmaceuticals Corp. Announces Fiscal 2007 Second Quarter Results, Updates Programs and Appoints Investor Relations Firm Apr 16, 2007
The Company continues to work with Dr. William Mobley's neuroscience laboratory at Stanford University, which has expertise in the study of neurotrophic factors, particularly Nerve Growth Factor (NGF). The laboratory at Stanford is testing engineered RAP peptides, which we call NeuroTrans(TM), in cell culture and preclinical models for their ability to enhance the transport of molecules from blood to the brain. (Canada Newswire)
Angels in the air Mar 1, 2007
The pilots all have photo IDs that they wear and file flight plans that begin with the letters "NGF." This lets air traffic controllers know that this is an Angel Flight. Ray and Lorraine Judd of Huddleston note that Angel Flights get priority handling if they face a long line at an airport. (Bedford Bulletin, VA)
Professor Uses Tai Chi To Fight Degenerative Nerve Disease Jan 25, 2007
(August 25, 1998) -- Implants to deliver nerve growth factor (NGF) to nerve cells in the brain were described here today (Aug ... (October 3, 1997) -- For the first time, scientists have shown through genetic studies in adult mice that depletion of the protein nerve growth factor (NGF) causes a decline in learning and memory, mimicking a major. (Science Daily)
