Malaria Vaccine Shows Promise in Small Trial Jan 25, 2008
THURSDAY, Jan. 24 (HealthDay News) -- A new malaria vaccine looked strong in a small trial conducted in Mali by a team of international researchers. The vaccine -- designed to prevent the malaria parasite from entering blood cells -- was safe and provoked strong immune responses (up to a sixfold increase in vaccine-specific antibodies) in the 40 adults who received it, according to the 17-member research team, based at the Malaria Research and Training Center at the University of Bamako. (Health-Finder)
Early promising results in malaria vaccine trial in Mali Jan 23, 2008
WHAT: A small clinical trial conducted by an international team of researchers in Mali has found that a candidate malaria vaccine was safe and elicited strong immune responses in the 40 Malian adults who received it ... A total of 60 participants were assigned at random to receive either a full or half-dose of the candidate malaria vaccine or a licensed rabies vaccine, which served as a control ... ARTICLE: MA Thera et al. Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults:... (EurekAlert!)
Making a malaria vaccine à la Louis Pasteur Dec 11, 2007
Making a malaria vaccine ... Making a malaria vaccine ... As many as 70 experimental programs exist around the world; eight rival projects are being supported by the Malaria Vaccine Initiative, which was established in 1999 with money from the Gates Foundation. (International Herald Tribune -- Health)
Trial of malaria vaccine alongside routine vaccines begins Dec 11, 2007
Kintampo (B/A), Dec. 10, GNA - A study has began at the Kintampo Health Research Centre (KHRC) to assess the use of a malaria vaccine given alongside routine vaccines already in use to immunise infants against childhood diseases ... The study is part of a phase two trial of the RTS,S malaria vaccine on-going among older children aged five to 17 months in six African countries aimed at assessing the safety of the vaccine, expected for use in Africa in 2011 should it meet all regulatory standards... (Ghana Web, Ghana)
Infectious Disease Research Institute Receives Grant from the Bill & Melinda Gates Foundation for Adjuvant Access and Development Dec 4, 2007
The grant will be used to provide adjuvants (essential components for many vaccines) for priority malaria vaccine candidates ... With this grant, IDRI will focus on adjuvants for malaria vaccines ... To accelerate the fight against malaria, IDRI will obtain access to adjuvants with proven clinical potential in malaria vaccines and will develop next-generation adjuvant formulations for malaria vaccine candidates. (PR Newswire)
Snapshot: Light relief Nov 15, 2007
He was recently commissioned by the Seattle Biomedical Research Institute which is working on a malaria vaccine to design a neon sculpture illustrating the feeding posture of anopheline mosquitoes. The exhibition, called The Shattering Glass: New Perspectives, runs until 24 February 2008. (Nature News Service)
Turning tragedy into triumph Nov 14, 2007
"Richards also wants to show people without such an illness that those with disorders can be valued members of society.Scott agrees."One of my best friends from high school is bipolar and is a molecular biologist at the Pasteur Institute, working on a malaria vaccine," she said. "Autism and other related disorders run in my family. My 19-year-old son, Reece, is high-functioning autistic and is finishing up his first semester at Georgetown University with all A's going into the last half of the... (Florida Today)
Defense bill boost for state firms Nov 14, 2007
4 million for VaxInnate, of New Haven to develop and test a synthetic malaria vaccine; plus $2 million for Oxley Inc., in Branford, for Future Medical Shelter System, a deployable medical shelter system that uses lights provided by Oxley; and $1. 6 million to the University of Connecticut to continue its program for developing advanced implantable nanosensors for tracking the health of soldiers. (New Haven Register, CT)
Whole parasite malaria vaccine to be manufactured for clinical trials Oct 30, 2007
Sanaria Inc. and the PATH Malaria Vaccine Initiative has officially opened a one-of-a-kind clinical manufacturing facility to produce a vaccine that uses a weakened form of the malaria parasite to fight a disease that annually kills more than one million people, most of them African children ... "The opening of this facility is an important step in the process to develop a whole-parasite malaria vaccine," said Dr. Stephen L. Hoffman, Sanaria's founder and CEO. "We are optimistic that the... (News-Medical.net)
Malaria vaccine hope for Africa's babies Oct 23, 2007
A malaria vaccine trial in Mozambique has shown that the treatment is safe and effective for babies aged just a few weeks ... The latest trial raises hopes that the malaria vaccine riddle has been cracked, and that babies can now be protected for the first two years of their lives: a strategy that could prevent millions of deaths ... "The vaccine has partial efficacy, so this will be another tool in the arsenal," says Christian Loucq, director of the PATH Malaria Vaccine Initiative, based in... (Nature News Service)
Achievement in Malaria Vaccine Trials in Africa Oct 23, 2007
Johannesburg: New research shown that an anti-malaria vaccine offering developed protection to children could be registered for use in four years, saving millions of young lives ... The safety of RTS,S/AS02D malaria vaccine has been confirmed in a clinical trail involving 214 infants, announced the scientists ... GlaxoSmithKline, a global pharmaceutical company, with the Malaria Vaccine Initiative by PATH, an international, non-profit health organization are developing the vaccine. (TopNews)
Introducing the New Malaria Vaccine: Hi Protection! Hi Safe! Oct 22, 2007
Introducing the New Malaria Vaccine: Hi Protection ... Introducing the New Malaria Vaccine: Hi Protection ... Introducing the New Malaria Vaccine: Hi Protection. (MedIndia)
Malaria vaccine kindles hope Oct 21, 2007
Scientists on Wednesday announced that trials of a new malaria vaccine, RTSS/AS02, had successfully cut the risk of infection in African children ... Scientists have been on the lookout for a malaria vaccine since the 1970s but no vaccine has demonstrated a protection rate of more than 35. (Times of India)
Successful Malaria Vaccine Also Proves Effective in Infants Oct 20, 2007
CURRENT ISSUE HIGHLIGHTS. New data shows that the RTS,S vaccine is safe and effective in infants By David Biello. (Scientific American)
A lifeline Malaria vaccine arrives at last Oct 20, 2007
A lifeline / Malaria vaccine arrives at last. Malaria vaccine arrives at last" /> Article:A lifeline / Malaria vaccine arrives at last:/c/a/2007/10/18/EDDESS74P.DTL Article:A lifeline / Malaria vaccine arrives at last:/c/a/2007/10/18/EDDESS74P.DTL SFGate Web by Editorial A lifeline Malaria vaccine arrives at last Friday, October 19, 2007 Georgia (default) Verdana Times New Roman Arial SF Chronicle Submissions Malaria is a lethal, statistical giant of a disease. It infects from 300 million to 500... (San Francisco Chronicle -- Opinion)
Malaria Vaccine Shows Promise Oct 20, 2007
THURSDAY, Oct. 18 (HealthDay News) -- Initial findings from tests of a malaria vaccine are encouraging, say researchers who tested the shot's safety and effectiveness in infants in Mozambique ... The team found that the malaria vaccine was safe and reduced the risk of contracting new malaria infections by 65 percent. (MEDLINEplus)
Experimental Malaria Vaccine Effective In Babies Oct 19, 2007
VOA News - Experimental Malaria Vaccine Proves Effective in Babies. A trusted source of newsand information since 1942. (Voice of America)
Malaria Vaccine Trial On Babies Shows Promising Results Oct 19, 2007
An early stage trial carried out in Africa of a malaria vaccine already shown to be effective in adults has suggested it is safe and even more effective for young babies, setting the stage for larger scale final phase trials ... 214 babies in Mozambique participated in the phase I/IIb double blind trial to test safety, immunogenicity, and efficacy of the malaria vaccine, currently referred to by its experimental name RTS,S/AS02D. ... "The trial was undertaken in an area of high transmission, but... (Medical News Today)
Mozambique: Infant Malaria Vaccine is Promising Oct 18, 2007
com: Mozambique: Infant Malaria Vaccine is Promising (Page 1 of 1) ... Mozambique: Infant Malaria Vaccine is Promising ... Initial findings from studies to test a malaria vaccine in African infants are promising, conclude authors of an article published in the Lancet. (allAfrica.com)
Md. biotech to develop malaria vaccine for military Sep 12, 2007
biotech to develop malaria vaccine for military - Baltimore Business Journal ... biotech to develop malaria vaccine for military ... The Gaithersburg-based biotech company, developing a number of gene-based drugs and vaccines, has signed a research and development pact with the Military Malaria Vaccine Program at the. (Bizjournals.com)
GenVec Up on Malaria Vaccine Contract Sep 11, 2007
Biopharmaceutical company GenVec Inc. said Monday it agreed to develop a malaria vaccine candidate against Plasmodium vivax with the U.S. Military Malaria Vaccine Program at the Walter Reed Army Institute of Research and the Naval Medical Research Center. Financial terms weren't disclosed. (Forbes)
Gates closes in on the end of a Microsoft era Jul 31, 2007
"I'll have also malaria vaccine or tuberculosis vaccine or curriculum in American high schools, which are also things that, at least the way my mind works, I sit there and say, 'Oh, God! This is so important; this is so solvable'," he said. "You've just got to get the guy who understands this, and this new technology will bring these things together.". (The Age, Australia -- Business)
Economists see aid to poor nations as ineffective Jul 19, 2007
Private companies have little financial incentive to develop a malaria vaccine, for example, but if rich nations pledged to buy the product for impoverished countries, firms would be more inclined to invest in the research. "The challenge is, how do you harness this good intention and good motives into better results?" Subramanian said. (AlertNet)
Microsoft Reveals Research Roadmap Jul 18, 2007
In addition, MSR itself has a team, headed by David Heckerman, an MSR computer science researcher who is also a medical doctor, that has been working on HIV and malaria vaccine studies. In order to further its goals, MSR has set up a network of 11 academic research centers across the globe to pursue research into a diverse set of technologies and goals, ranging from computational biology to collaboration techniques in the classroom to pen-based computing, Sailesh Chutani, director of External... (CIO Information Network)
People to watch: Robert Bernard Jun 8, 2007
We've recently announced initial human trials of a TriGrid melanoma vaccine with Memorial Sloan-Kettering Cancer Center in New York, and have plans to start testing of an HIV vaccine and a malaria vaccine with TriGrid later this year. What about your job keeps you up at night. (San Diego Union-Tribune -- Business)
Antibody-based Therapies Effective At Controlling Malaria May 19, 2007
The model described in this study provides both a test for therapeutic antibody efficacy prior to clinical trials in humans and an important tool in malaria vaccine development. This study was supported by a Medical Research Council Career Establishment Award, a European Union Marie Curie Excellence Grant, Antibody Immunotherapy for Malaria, and a ROPA (Realizing Our Potential Award). (Science Daily)
Students Devise Oral Quick-dissolve Strips For Rotavirus Vaccine May 16, 2007
"This is probably the second-most important childhood vaccine needed in the developing world, right behind a malaria vaccine," he said. "The mortality rate is high.". (Science Daily)
GenVec's malaria vaccine collaboration receives funding May 3, 2007
GenVec has amended and extended its research and development agreement with the Path Malaria Vaccine Initiative, actions that provide for up to $750,000 in additional funding through the end of this year to continue work on a new malaria vaccine ... GenVec is one of several companies in the Washington area, including Rockville-based Sanaria, attempting to commercialize a new malaria vaccine, which experts say could generate hundreds of millions of dollars, if not billions, in annual sales if... (Washington Business Journal, DC)
Who Should Foot the Bill on Climate Change? Mar 11, 2007
By contrast, R&D to discover and develop a malaria vaccine can reduce malaria prevalence across-the-board ... The example of the malaria vaccine is best thought of as a metaphor for the kind of development that's needed. (YaleGlobal Online Magazine, CT)
Chomsky: Iraq Interview Feb 21, 2007
Right now there's discussion of putting serious effort into developing a malaria vaccine, because global warming might extend malaria to the rich countries, so something should be done about it. . (Zmag.org)
Debate over global warming is shifting Feb 15, 2007
Adapting to a warmer global climate, he said, could include anything from building farther inland to guard against rises in sea level to investing in a malaria vaccine, anticipating that disease-carrying mosquitoes could spread northward from the tropics. The debate shift has been felt elsewhere as well. (Boston Globe)
PATH names new exec Feb 4, 2007
In her new position, Sherris will oversee PATH's global programs including HIV, AIDS and tuberculosis, immunization, a malaria vaccine initiative, maternal and child health and nutrition, a meningitis vaccine project, reproductive health, technology solutions and vaccine development. PATH, based in the north Seattle neighborhood of Ballard, develops low-cost health technologies for use in the developing world. (Puget Sound Business Journal, WA)
WHO: Vaccine effort saves 2.3m young lives Jan 27, 2007
Bill Gates added that "Vaccines are a miracle thing, and as we can add, some day, perhaps a malaria vaccine, some day a TB vaccine, or an AIDS vaccine, the infrastructure and the capacity that GAVI has built out" will prove essential to saving millions more lives. Arthur Allen , author of the just-published "Vaccine: The Controversial Story of Medicine's Greatest Lifesaver," compared Bill Gates to John D. Rockefeller, two businessmen who "used their billions to do something good for humanity."... (Boston Globe)
FEATURE: Kintampo Children - Africa's stars in the making Jan 17, 2007
The children are participating in an experiment the Kintampo Health Research Centre in the Brong Ahafo Region is conducting on a candidate malaria vaccine ... Results also showed that the protective effect of the malaria vaccine did not wane 24 months after the vaccine was administered ... This experiment would serve as a basis for introducing the malaria vaccine into the Expanded Programme on Immunization, (EPI) a programme, where children are protected against major childhood killer diseases... (Ghana Web, Ghana)
Malaria vaccine expected in 2011 Jan 9, 2007
Kintampo, (B/A), Jan. 8, GNA - A health expert announced that scientists have targeted 2011, for the introduction of RTS,S (rpt RTS,S) malaria vaccine, which was currently going through clinical trials, for use in Ghana and across Africa to control malaria ... Results also showed that the protective effect of the malaria vaccine did not wane 24 months after the vaccine was administered. (Ghana Web, Ghana)
Vaccine monitor says no adverse report on vaccine trial on children Jan 9, 2007
Kintampo, (B/A), Jan. 8, GNA- Dr Sam Newton, the local expert monitoring the safety of the vaccine administration in Ghana, gave the assurance that there has been no life-threatening report on the phase two malaria vaccine trials on 540 children, taking place in the country. He also said there was no violation of protocol or rules formulated to guide persons involved in the clinical trials and that both local and international monitoring was ongoing to protect the children. (Ghana Web, Ghana)
