Cigarettes Harbor Many Pathogenic Bacteria Nov 20, 2009
Bacteria of medical significance to humans were identified in all of the tested cigarettes and included Acinetobacter (associated with lung and blood infections); Bacillus (some varieties associated with food borne illnesses and anthrax); Burkholderia (some forms responsible for respiratory infections); Clostridium(associated with foodborne illnesses and lung infections); Klebsiella (associated with a variety of lung, blood and other infections); and Pseudomonas aeruginosa (an organism that... (Science Daily)
Calixa Therapeutics to Make Multiple Presentations on CXA-101 and CXA-101/tazobactam at the 49th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy Sep 12, 2009
F1-1993: Activity of CXA-101 plus Tazobactam against ESBL-Producing Escherichia coli and Klebsiella pneumoniae ... F1-1996: In Vitro Assessment Using Time-kill Curves of CXA-101 (CXA)/Tazobactam (TAZ) Against Escherichia coli (EC), Klebsiella pneumoniae (KP), and Pseudomonas aeruginosa (PA) Strains. (PR Newswire)
Novexel Presents 16 Posters and one Slide Presentation at the 49th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) Meeting in San Francisco Sep 11, 2009
Poster A1-006 shows that the NXL104/ceftazidime is efficacious in a pneumonia model using a strain of Klebsiella pneumoniae expressing elevated levels of AmpC beta-lactamase. Poster B-1339, shows that NXL104/ceftazidime is very effective in two murine models of infection against a strain of Klebsiella pneumoniae harboring the KPC carbapenemase, which has been shown to confer resistance to all other beta-lactams and beta-lactamase inhibitor combinations. (PR Newswire)
Colicky babies can frustrate any parent Aug 28, 2009
Researchers studying babies who had colic found the bacterium klebsiella along with gut inflammation in the intestines of all babies in their study. "We believe that the bacterium may be sparking an inflammatory reaction, causing the gut inflammation," Dr. J. Marc Rhoads, a pediatrics professor at the University of Texas Medical School at Houston and the study's lead investigator, said in a news release. (Honolulu Advertiser)
Bacteria May Be Connected to Colic Aug 8, 2009
Called Klebsiella, it could be causing gut inflammation, study suggests ... Researchers found the bacterium Klebsiella along with gut inflammation in the intestines of all babies in their study who had colic, a condition characterized by uncontrollable crying ... He said the researchers plan further study, involving adults as well as infants, on Klebsiella and on whether probiotics, a dietary supplement of so-called good bacteria, could control the gut inflammation in colicky babies. (MEDLINEplus)
Antibacterial and phytochemical screening of Anethum graveolens, Foeniculum vulgare and Trachyspermum ammi Aug 6, 2009
Hot water and acetone seed extracts showed considerably good antibacterial activity against all the bacteria except Klebsiella pneumoniae and one strain of Pseudomonas aeruginosa. Minimum inhibitory concentration for aqueous and acetone seed extracts ranged from 20-80 mg/ml and 5-15 mg/ml respectively. (BioMed Central)
Colic In Babies May Be Caused By Gut Bacteria Jul 25, 2009
Published in the July 23 online edition of the Journal of Pediatrics, the study pointed to an organism called Klebsiella, a normally occurring bacterium that can be found in the mouth, skin and intestines ... A larger study is needed to examine Klebsiella and the use of a probiotic, which is a dietary supplement made up of good bacteria, to control the gut inflammation ... A new study pointed to an organism called Klebsiella, a normally occurring bacterium that can be found in the mouth, skin... (Science Daily)
A Living Antibiotic, Anyone? Jul 2, 2009
Gram negative infections are the cause of a range of human infectious diseases, ranging from typhoid (Salmonella typhi), dysentery (Klebsiella, Proteus, E.coli, Granuloma ) eye infections (Pseudomonas aeruginosa), respiratory and urinary tract infections (Serratia marcescens), to plague (Yersinia pestis), acidity and stomach cancers (Helicobacter pyroli) Resistance to common antibiotics is fast developing in these species. This is worrisome as the bugs seem to alter themselves and gain... (Suite101.com)
New lab-on-a-chip measures mechanics of bacteria colonies Jul 1, 2009
The experiments were performed on colonies of Staphylococcus epidermidis and Klebsiella pneumoniae, which are known to cause infections in hospitals. The new microfluidic device could also be used to measure the resistance of various other soft-solid materials in the consumer products, food science, biomaterials and pharmaceutical fields. (EurekAlert!)
Angelica Corporation Raises Bar Again for Increased Patient Safety Jun 5, 2009
Angelica gives healthcare providers added confidence that their linens are sanitized against MRSA, Staph, Klebsiella pneumoniae, and Pseudomonas aeruginosa. O'Hara added, "AdvaCare fundamentally and directly addresses the provider's efforts for HAI prevention.". (PR Newswire)
Novexel to Present Four Posters at the 19th European Congress of Clinical Microbiology and Infectious Diseases in Helsinki May 18, 2009
The poster provides in vitro data showing that a ceftazidime/NXL104 combination is rapidly bactericidal against a range of beta-lactamase-producing strains of Enterobacteriaceae, including E. coli, and Klebsiella. Data presented also showed that one of the most important factors affecting the pharmacodynamics of the combination is maintaining a critical concentration of the inhibitor (NXL104) to suppress beta-lactamase activity. (PR Newswire)
BUSM researchers find gram-negative rods in two Philippine neonatal intensive care units May 16, 2009
The most common GNR species identified were Klebsiella, Acinetobacter, Pseudomonas aeruginosa and Enterobacter. A high proportion of colonization and bacteremia at the two NICUs was with non-intestinal GNRs. (EurekAlert!)
What to Do if Bitten by a Dog or Ca... Apr 18, 2009
Aside from streptococcus or staphylococcus infections dogs may also incur pasteurella multocida, capnocytophaga canimorses (rare but especially dangerous), klebsiella and enterobacteria. MRSA becomes a concern only if the in the past the dog has gotten the infection from the human he associates with. (Suite101.com)
Clinical outcomes of spontaneous bacterial peritonitis due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species: A retrospective matched case-control study Apr 13, 2009
Clinical outcomes of spontaneous bacterial peritonitis (SBP) due to extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species (ESBL-EK) have not been adequately investigated. Methods. (BioMed Central)
Research Could Lead To New Non-antibiotic Drugs To Counter Hospital Infections Apr 10, 2009
11, 2008) A research team examining bacterial isolates obtained in hospital and non-hospital clinical settings between 2000 and 2006, has identified drug-resistant strains of E. coli and Klebsiella bacteria in. (July 7, 2008) By targeting the gene that confers resistance to antibiotics, a new drug may be able to finally outwit drug-resistant staph. (Science Daily)
Superbug risk to war wounded Mar 30, 2009
The potentially lethal microbes include superbugs such as methicillin resistant Staphylococcus aureus (MRSA), Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella species and Escherichia coli. Dr Clinton K. Murray, from Brooke Army Medical Center, USA, told the Society for General Microbiology Meeting at the International Centre, Harrogate, that at the beginning of the 20th century improved military hygiene and disease control led to a steady decline in the number of wartime deaths... (EurekAlert!)
Press statement on new CDC MMWR on Klebseilla pneumonia Carbapenemase-producing organisms Mar 19, 2009
"The new guidelines highlight the need to educate clinicians and public health professionals about the importance of screening for Klebsiella pneuomoniae Carbapenemase (KPC)-Producing Organisms. If hospitals follow the CDC guidelines to detect and identify Klebsiella and Carbapenemase, then we can potentially halt the transmission of a highly treatment-resistant Gram-negative organism and prevent a large scale public health problem. While KPC is still rare and occurs only sporadically in most... (EurekAlert! -- Business News)
Novel Antibiotics Don't Trigger Resistance Mar 15, 2009
He notes that many other aggressive bacterial pathogens S. pneumoniae, N. meningitides, Klebsiella pneumoniae, and Staphylococcus aureus express MTAN and therefore would probably also be susceptible to these inhibitors. While this study involves three compounds, Dr. Schramm says that his team has now developed more than 20 potent MTAN inhibitors, all of which are expected to be safe for human use: Since MTAN is a bacterial enzyme, blocking it will have no effect on human metabolism. (Science Daily)
Gram-negative bacteria are drug-resistant superbugs to watch out for Feb 23, 2009
They are extremely drug-resistant; they have long, complicated names like "acinetobacter baumanii" and "klebsiella pneumoniae." Two important issues related to these bacteria: They are increasingly cropping up in hospitals, and they are nearly impossible to treat. Is this related to the Brazilian model who recently died from a bacterial infection. (CNN)
Report: U.S. running out of drugs to treat deadly bug Feb 18, 2009
Acinetobacter doesn't garner as many headlines as methicillin-resistant Staphylococcus aureus, the dangerous superbug better known as MRSA, but drug-resistant strains of Acinetobacter baumannii and two other microbes -- Pseudomonas aeruginosa and Klebsiella pneumoniae -- could soon produce a toll to rival MRSA's, the Los Angeles Times warned ... Klebsiella causes a sudden, severe pneumonia, mostly in people already suffering from ailments such as diabetes or chronic lung disease. (Xinhuanet, China)
Drug-resistant strains of bacteria on the rise Feb 18, 2009
Acinetobacter doesn't garner as many headlines as methicillin-resistant Staphylococcus aureus, the bacterium better known as MRSA. But a January report by the Infectious Diseases Society of America warned that drug-resistant strains of Acinetobacter baumannii and two other microbes - Pseudomonas aeruginosa and Klebsiella pneumoniae - soon could rival MRSA's toll. The three bugs belong to a large category of bacteria called "gram-negative" that are especially hard to fight because they are... (Boston Globe)
