HIV & AIDS Dec 10, 2008
PML is an extremely serious brain infection caused by the human polyomavirus JC virus. Signs and symptoms vary and may include speech problems, weakness on one side of the body, loss of vision in one eye, or numbness in one arm or leg. (CNN -- Health)
Malignant Gliomas in Adults Oct 23, 2008
Other DNA viruses, such as JC virus, have been implicated in glioma pathogenesis. 3 In this regard, it is also important to note that detection of atypical nuclei and high-proliferation indexes in a brain biopsy led to, in at least one instance, the misdiagnosis of a. (New England Journal of Medicine)
Dog neglected, matted, multiple tumors Sep 19, 2008
He also had the JC virus, which causes an infection of the brain and spinal cord in people with AIDS.. After his dog was euthanized, Mr. Gibson told the Citizen that when he returned home about a month after he was admitted to hospital, it was to find his dog, Damien, in rough shape. (Pet-Abuse.com)
PML and MS Therapy Aug 3, 2008
PML occurs as a result of viral infection of the brain with either JC virus or BK virus. Most people actually carry these viruses in a dormant state since they have already been infected with them at an early age. (Suite101.com)
2 patients in Tysabri study found to have JC virus Mar 5, 2008
Citing a summary of a presentation set for April at the American Academy of Neurology, Corey Davis, an analyst at Natixis Bleichroeder, said an examination of 175 patients treated at one center found two cases of JC virus - one in the cerebrospinal fluid and one in the plasma. But he noted neither showed any signs of progression to progressive multifocal leukoencephalopathy, the potentially deadly brain infection. (Boston Globe)
New Therapeutic Target For Treatment Of Multiple Sclerosis Jan 25, 2008
However, they also impede the immune system's ability to provide protection against chronic viral infections of the central nervous system, such as progressive multifocal leukoencephalopathy, a demyelinating disease of the central nervous system caused by the JC virus. Since ALCAM/CD166 blockade does not affect CD8+ T cell migration, whose main function is to destroy cells infected by viruses and neoplastic cells, the study results suggest that CNS immune protection against viruses would not be... (Science Daily)
New Virus May Be Responisble For Unexplained Respiratory Infection May 19, 2007
For example, one of the most infamous polyoma viruses, the JC virus, is a leading secondary infection in HIV patients. It causes a life-threatening neurological disorder called progressive multifocal leukoencephalopathy. (Science Daily)
Scientists Reveal Virus' Secret Weapon: Sheds Light On How Brain, Kidney Viruses Infect Jan 30, 2007
While SV40 doesn't normally infect humans (it has been found in humans and was likely introduced in the 1950s via a contaminated polio vaccine), its compatriots, the polyomaviruses known as JC virus and BK virus do, and sometimes fatally. These new findings may lead to new strategies for treating or preventing infection by polyomavirus. (Science Daily)
