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    News and Articles on Idiopathic

    Archives: Idiopathic

    Keeping an Open Mind  Jan 1, 2009
    He had undergone heart transplantation 6 years earlier for idiopathic cardiomyopathy. He reported no weight loss, night sweats, or chills. (New England Journal of Medicine)

    Woman's Christmas wish — healthy baby — granted  Dec 26, 2008
    Alley, of Marietta, was born with chronic idiopathic intestinal pseudo obstruction, a disease that prevents the intestines from absorbing food and causes severe abdominal pain. The only thing that could save her was a small bowel transplant, a surgery performed on only 100 to 150 people in the United States annually. (Atlanta Journal-Constitution -- Metro)

    Kids with Arthritis Often Disabled  Dec 20, 2008
    NEW YORK (Reuters Health) - Although many children with so-called juvenile idiopathic arthritis have a low level of disease, about one in five have moderate to severe disability, Italian researchers report. "These findings," Dr. Angelo Ravelli told Reuters Health, "underscore the critical need for treatments and treatment strategies that have the ability to better control disease activity.". (MEDLINEplus)

    'Kevin and Perry' hormone  Dec 13, 2008
    In this study, the researchers studied nine families in which some members had a condition called normosmic idiopathic hypogonadotropic hypogonadism (nIHH). This condition is hereditary and involves a severe deficiency in the production of gonadotrophins, which prevents a normal progression to puberty. (NHS Choices)

    Novel Therapeutic Approaches May Transform Treatment and Improve Patient Outcomes in Several Platelet Disorders  Dec 8, 2008
    SAN FRANCISCO, Dec. 6 /PRNewswire-USNewswire/ -- Four studies that highlight significant advances in treatment and survival outcomes for patients with various forms of thrombocytopenia, a group of bleeding disorders characterized by a low number of platelets in the blood, will be presented in a press conference on Saturday, December 6, at 8:00 a.m., during the 50th Annual Meeting of the American Society of Hematology in San Francisco, CA. The studies featured in the press conference will report... (PR Newswire)

    GSK Reports PROMACTA(R) (eltrombopag) Significantly Increased Platelet Counts and Reduced Bleeding in Long-Term Study of Patients With Chronic ITP  Dec 7, 2008
    - RAISE Phase III data presented at American Society of Hematology show the efficacy and safety of PROMACTA in patients with chronic immune (idiopathic) thrombocytopenic purpura (ITP) over a six month treatment period - Patients receiving PROMACTA were eight times more likely than placebo to sustain elevated platelet counts - Patients receiving PROMACTA experienced decreased bleeding symptoms and a reduced need for concomitant and rescue ITP medications. PHILADELPHIA, Dec. 6... (PR Newswire)

    Bayer Announces Upcoming Presentations of Campath(R) and Leukine(R) Data at the 50th Annual Meeting of the American Society of Hematology  Dec 6, 2008
    Cytopenias: Serious, including fatal, pancytopenia/marrow hypoplasia, autoimmune idiopathic thrombocytopenia, and autoimmune hemolytic anemia can occur in patients receiving Campath. Single doses of Campath greater than 30mg or cumulative doses greater than 90mg per week increase the incidence of pancytopenia. (PR Newswire)

    Roche and FDA Agree on Pathway Towards U.S. Approval of ACTEMRA(R) (tocilizumab)  Dec 4, 2008
    ACTEMRA is part of a co-development agreement between Roche and Chugai Pharmaceutical Co. In June 2005, ACTEMRA was launched by Chugai in Japan as a therapy for Castleman's disease; in April 2008, additional indications for rheumatoid arthritis, juvenile idiopathic arthritis and systemic-onset juvenile idiopathic arthritis were also approved in Japan. The serious adverse reactions reported in ACTEMRA clinical studies include serious infections, gastrointestinal perforations and hypersensitivity... (PR Newswire)

    Inherited Genetic Cause, Possible Treatment Found For Complex Lung Disorder  Nov 26, 2008
    28, 2005) An incurable, deadly lung disorder, "idiopathic interstitial pneumonia" (IIP), whose causes were mysterious arises from a combination of a genetic predisposition and damage due to inhaled chemicals. (Jan. (Science Daily)

    FDA Approves Promacta(R) (Eltrombopag), the First Oral Medication to Increase Platelet Production for People With Serious Blood Disorder  Nov 21, 2008
    PHILADELPHIA, Nov. 20 /PRNewswire-FirstCall/ --GlaxoSmithKline (NYSE: ) today announced that the United States Food and Drug Administration (FDA) granted accelerated approval for PROMACTA(R) (eltrombopag) for the treatment of thrombocytopenia in patients with chronic immune (idiopathic) thrombocytopenic purpura (ITP) who have had an insufficient response to corticosteroids, immunoglobulins or splenectomy ... Feudjo-Tepie M, Robinson N, Bennett D. Prevalence estimates of adult chronic idiopathic... (PR Newswire)

    A Man with Chronic Daily Headache  Nov 20, 2008
    Idiopathic Hypertrophic Pachymeningitis. Pachymeningitis Due to Infection. (New England Journal of Medicine)

    Juvenile Arthritis Teens Less Physically Active  Nov 13, 2008
    NEW YORK (Reuters Health) - Physical activity levels are low in adolescents with juvenile idiopathic arthritis, and this appears to be unrelated to disease activity, study findings in the journal Arthritis and Rheumatism indicate ... "To our knowledge, physical activity has not previously been studied in adolescents with juvenile idiopathic arthritis." ... Previously referred to as juvenile rheumatoid arthritis, juvenile idiopathic arthritis begins before the age of 16 years, causing pain,... (MEDLINEplus)

    Differences between CFS/ME and FM  Nov 12, 2008
    Fibromyalgia, on the other hand, is often triggered by a physical injury or trauma, but sometimes it is fully idiopathic (no cause or trigger is found). Some doctors consider both CFS/ME and fibromyalgia to be autoimmune diseases. (Suite101.com)

    Hormone Therapy Helps Short Children Grow Up, Study Finds  Nov 8, 2008
    (June 7, 2005) A randomized UCLA study found that a new dosing paradigm can improve height outcomes in the treatment of children who have short stature due to growth hormone deficiency and idiopathic short. (Dec. (Science Daily)

    LRRK2 gene penetrance and Parkinson's disease susceptibility  Nov 6, 2008
    We report age-dependent penetrance estimates for leucine-rich repeat kinase 2 (LRRK2) related Parkinson's disease in a large sample of familial PD. The most frequently seen LRRK2 mutation, Gly2019Ser (G2019S), is associated with approximately 5-6% of familial PD cases and 1-2% of idiopathic cases making it the most common known genetic cause of PD. Studies of the penetrance of LRRK2 mutations have produced a wide range of estimates, possibly due to differences in study design and recruitment,... (BioMed Central)

    New Study Shows that PEGASYS(R) Regimen Provides Higher Sustained Virological Response Rates for Hepatitis C Patients  Nov 2, 2008
    Serious adverse events in hepatitis C trials included neuropsychiatric disorders (homicidal ideation, suicidal ideation, suicide attempt, suicide, psychotic disorder and hallucinations), serious and severe bacterial infections (sepsis), bone marrow toxicity (cytopenia and rarely, aplastic anemia), cardiovascular disorders (hypertension, supraventricular arrhythmias and myocardial infarction), hypersensitivity (including anaphylaxis), endocrine disorders (including thyroid disorders and diabetes... (PR Newswire)

    New Gene Responsible For Puberty Disorders Identified  Oct 31, 2008
    These disorders idiopathic hypogonadotropic hypogonadism, or IHH, and Kallmann syndrome short circuit puberty and can cause infertility. Kallmann syndrome is also marked by patients inability to smell. (Science Daily)

    DATA from Overseas Phase III Trial of "Actemra" a Humanized Anti-Human IL-6 Receptor Monoclonal Antibody, Demonstrates Efficacy in Preventing Structural Joint Damage in Rheumatoid Arthritis Patients  Oct 27, 2008
    In April 2008, additional indications were approved in Japan for rheumatoid arthritis (including prevention of structural damage of joints), polyarticular-course juvenile idiopathic arthritis and systemic juvenile idiopathic arthritis. Outside of Japan, Roche and Chugai are investigating ActemraR in five phase III international trials. (JCN Network, Japan)

    First Gene For Clubfoot Identified  Oct 25, 2008
    About 80 percent of clubfoot cases are idiopathic, meaning the cause is unknown and the patient has no other birth defects ... Gurnett said some clinical characteristics of the family members with the PITX1 mutation suggest that the genetic defect may be linked to idiopathic clubfoot. (Science Daily)

    Supreme Court Chief Taken to Hospital After Fall  Oct 25, 2008
    Roberts, 52, fell on a dock after having a "benign idiopathic seizure," said Kathleen Landin Arberg, the court's public information officer ... Arberg's description of a benign idiopathic seizure indicates an episode whose origins are unknown. (Yahoo News -- Supreme Court)

    A Woman with Dyspnea on Exertion  Oct 23, 2008
    Idiopathic Interstitial Lung Disease. Summary. (New England Journal of Medicine)

    Disease Leads To Vision Loss More Often In Men  Oct 18, 2008
    Idiopathic intracranial hypertension (IIH) is a neurological disorder involving too much cerebrospinal fluid pressure, resulting in severe headaches, swelling of the optic nerves, vision loss, double vision, and a whooshing noise in the ears ... 10, 2008) Black people are more likely to lose vision as a result of idiopathic intracranial hypertension, or increased pressure in the brain, according to a new study ... The cause of idiopathic intracranial. (Science Daily)

    Brain Pressure More Likely to Cause Vision Loss in Men  Oct 17, 2008
    People with the condition, known as idiopathic intracranial hypertension (IIH), have too much cerebrospinal fluid pressure, which can cause severe headaches, a whooshing noise in the ears, swelling of the optic nerves, double vision, and vision loss. The condition affects about one in 5,000 people, and is more common in women. (MEDLINEplus)

    Family honors Peggy Betts with benefit to help cure IPF  Oct 17, 2008
    But many other cases are idiopathic, meaning there is no apparent cause. There is no known cure or effective treatment for PF other than a lung transplant, though some symptoms can be improved with oxygen and medications. (Weymouth News, MA)

    The Tyranny of Diagnosis  Sep 19, 2008
    When the diagnosis trajectory and patient picture don t match, we are left with an atypical, complicated, idiopathic or undiagnosable case. One of the risks for these patients, in addition to prolonged physical discomfort or suffering, is that without a diagnosis, their experience may lose meaning and relevance in the eyes of others. (Atlanta Journal-Constitution -- Health)

    Al Dente: When mouth pain is not dental pain  Sep 19, 2008
    However, the cause may not be found; medicine refers to this as primary or idiopathic burning mouth syndrome. Patients who present to their dentist with pain expect relief quickly. (Malden Observer, MA)

    S*BIO Initiates U.S. Phase I Clinical Trials of Oral JAK2 Inhibitor SB1518 for the Treatment of Hematological Malignancies  Sep 18, 2008
    The V617F mutation is found in high frequencies in various myeloproliferative disorders such as idiopathic myelofibrosis. SB1518 might also provide an effective treatment for other hematological malignancies with mutations and re-arrangements in the JAK2 gene. (PR Newswire)

    Urinary Frequency  Sep 11, 2008
    This conditions has many names which are mostly synonymous: irritable bladder, overactive bladder or idiopathic bladder spasm. When the problem occurs at night it is called nocturia. (Suite101.com)

    Renal Phosphate–Transporter Regulatory Proteins and Nephrolithiasis  Sep 11, 2008
    Nephrolithiasis is a common disorder, and idiopathic hypercalciuria is the most frequent metabolic disorder associated with nephrolithiasis. 1 Several studies have shown that subjects with idiopathic hypercalciuria have phosphaturia or renal phosphate leak. (New England Journal of Medicine)

    Medical opinion: Burning feet could be peripheral neuropathy  Sep 8, 2008
    This is called idiopathic neuropathy. Not all peripheral neuropathy can be cured but most can be controlled. (Yuma Daily Sun, AZ)

    Health Buzz: Immunosuppressive Drug Warning and Other Health News  Sep 7, 2008
    The drugs suppress the immune system and are approved to treat such conditions as rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, plaque psoriasis, ankylosing spondylitis and Crohn's disease. The drugs already carry black-box warnings related to different safety issues, including fungal infections. (U.S. News & World Report)

    FDA Demands Tougher Warnings on Immunosuppressive Drugs  Sep 6, 2008
    The drugs, Humira, Cimzia, Enbrel and Remicade, belong to a class of medications known as tumor necrosis factor alpha blockers (TNF-alpha blockers), which suppress the immune system and are approved to treat several conditions including rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, plaque psoriasis, ankylosing spondylitis and Crohn's disease. All four drugs already carry black-box warnings related to different safety issues, including fungal infections. (MEDLINEplus)

    Arthritis drugs must carry stern warnings  Sep 5, 2008
    The medicines are approved to treat a variety of conditions, including rheumatoid arthritis, juvenile idiopathic arthritis, psoriasis, and Crohn's disease. They work by blocking the inflammatory protein called tumor necrosis factor-alpha, or TNF-alpha. (Boston Globe)

    HEALTH BLOG: Opening up the medicine chest  Sep 2, 2008
    Medicine chest - Better Life - USATODAY.com. Grapefruit juice can reduce drug absorption, too. (USA Today -- Money)

    The first autism disease genes  Sep 2, 2008
    A higher recurrence risk in families with autistic subjects (45-times greater than the prevalence in the general population) and higher concordance for autism among monozygotic (60-90%) than dizygotic (0-10%) twins argue for a genetic predisposition to idiopathic autism. These data are interpreted as showing that liability to autism is in large part due to oligogenic inheritance in which a combination of multiple possibly interacting susceptibility alleles results in autism. (EurekAlert!)

    How The Brain Compensates For Vision Loss Shows Much More Versatility Than Previously Recognized  Aug 28, 2008
    10, 2008) Black people are more likely to lose vision as a result of idiopathic intracranial hypertension, or increased pressure in the brain, according to a new study. The cause of idiopathic intracranial. (Science Daily)

    Chief justice tumbles after seizure  Aug 28, 2008
    Doctors called the incident a "benign idiopathic seizure," similar to one suffered by the chief justice in 1993, the court statement said. An idiopathic seizure is one with no identifiable physiological cause. (Yahoo News -- Supreme Court)

    HEALTH BLOG: Digging into the latest cancer studies  Aug 28, 2008
    Known as (TNF) blockers, they're used to treat juvenile idiopathic arthritis (formerly called juvenile rheumatoid arthritis) and , a type of inflammatory bowel disease. Blocking the protein TNF reduces inflammation but also raises the risk of infection. (USA Today -- Money)

    A conversation with Kobe Marinko and his mother, Lee Marinko  Aug 22, 2008
    According to the Arthritis Foundation's Website, Idiopathic Polyarticular JRA affects five or more joints of a child, and more girls than boys. Kobe and his family found out that he had JRA in the spring of 2007. (Danvers Herald, MA)

    Obituaries for Thursday, Aug. 21, 2008  Aug 21, 2008
    Richard E. Wieman of La Crosse went to join his Mom, Dad, brother and sister in heaven after a long battle with idiopathic pulmonary fibrosis on Tuesday, Aug. 19, 2008, at the age of 68. He was proud to serve his country from 1958 to 1963 as a Navy crash crew firefighter. (La Crosse Tribune, WI)

    Idiopathic Sudden Sensorineural Hearing Loss  Aug 21, 2008
    Steven D. Rauch, M.D.. Since this article has no abstract, we have provided an extract of the first 100 words of the and any section headings. (New England Journal of Medicine)

    Causes of Chronic Fatigue  Aug 14, 2008
    Chronic Idiopathic Fatigue. Chronic idiopathic fatigue refers to persistent fatigue whose cause could not be found despite thorough examination. (Suite101.com)

    Laryngeal Paraysis in Dogs and Cats  Aug 14, 2008
    Most of the time laryngeal paralysis is idiopathic, meaning there is no known cause. Laryngeal paralysis may be congenital in Bouvier de Flandres, Siberian Huskies, Dalmatians, Rottweilers, and Bull Terriers. (Suite101.com)

    Danvers youth to lead 12th annual Boston Arthritis Walk  Aug 8, 2008
    Marinko was diagnosed with idiopathic polyarticular juvenile rheumatoid arthritis just over a year ago. Marinko is joining Honorary Chair Bob Lobel to raise funds and awareness of arthritis, which impacts 46 million Americans. (Danvers Herald, MA)

    HEALTH BLOG: Read the latest child wellness tips  Aug 5, 2008
    Parenting and kids' health - Better Life - USATODAY.com. Unhappy about Happy Meals and the like. (USA Today -- Money)

    Note to people with scarred and stiffened lungs: Monitor your sleep before severe fatigue sets in  Jul 30, 2008
    D., who treated Spaeth, found more than twice the amount of nighttime sleep disturbances and double the number of daytime episodes of drowsiness among 41 men and women with so-called idiopathic pulmonary fibrosis than in people with healthy lungs. "Physicians should strongly consider monitoring people with this scarring lung disease for sleep disorders as part of their standard care, because poor sleep has a profound effect on their quality of life," says Danoff, an assistant professor at the... (EurekAlert!)

    Health Canada approves ORENCIA(R) (abatacept) for the treatment of moderate-to-severe juvenile idiopathic arthritis (JIA) in patients six years and older  Jul 29, 2008
    ORENCIA is a First-in-Class Biologic Treatment Option Now Available for Use in Pediatric Patients with JIA MONTREAL, July 29 /CNW Telbec/ - Bristol-Myers Squibb Canada today announced that Health Canada has approved ORENCIA(R) (abatacept) for reducing signs and symptoms of moderately to severely active juvenile idiopathic arthritis (JIA)/juvenile rheumatoid arthritis in pediatric patients 6 years of age and older who have had an inadequate response to one or more DMARDs, such as MTX ... The... (Canada Newswire)

    Custom-Made Insoles May Ease Certain Foot Pain  Jul 25, 2008
    Besides showing promise for painful high arches and bunions, the researchers found that custom orthoses may ease foot pain from juvenile idiopathic arthritis -- a form of arthritis that affects children. In these cases, though, it was not clear that custom orthotics were any more effective than "off-the-shelf" shoe inserts. (MEDLINEplus)

    Prescription for disaster  Jul 21, 2008
    He stayed at the hospital 10 days, sedated by a morphine pump, and was eventually diagnosed with idiopathic pancreatitis, a rare, painful stomach condition. At the end of the hospital stay, Havelka was prescribed two weeks bedrest and two types of opiate painkillers OxyContin, a time-release version (contin is short for continual release) of the narcotic oxycodone, which he was also given, mainly for immediate pain relief. (Helena Independent Record, MT)

    Prescription for Addiction: Painkillers for stomach condition spiraled out of control, almost ending man's life  Jul 21, 2008
    He stayed at the hospital for 10 days, sedated by a morphine pump, and was eventually diagnosed with idiopathic pancreatitis, a rare but painful stomach condition. At the end of the hospital stay, Havelka was prescribed two weeks' bedrest and two types of opiate painkillers OxyContin, a time-release version ( contin is short for continual release) of the narcotic oxycodone, which he was also given, mainly for immediate breakthrough pain relief. (Missoulian, MT)

    Overview of Bell's Palsy  Jul 20, 2008
    Diagnosis and Treatment of Idiopathic Facial Nerve Paralysis ... Rather, Bell's palsy is an idiopathic facial paralysis, one whose cause cannot be determined ... Assuming the facial paralysis is idiopathic and can be appropriately called Bell's palsy, the treatment includes the corticosteroid medication prednisone and a drug against herpes simplex virus (HSV), which can be acyclovir, valacyclovir, or famciclovir. (Suite101.com)

    Rebatis father lodges police complaint  Jul 20, 2008
    Kahanr has alleged that on Wednesday at around 9 in the morning, a staff nurse named Malati Swain had come and drew blood from both him and his daughter, who is undergoing a series of surgeries to get rid of the deformities caused by the rare idiopathic gingival enlargement disease at the SCB Medical College and Hospital. The nurse had said that she was doing so on instructions of treating surgeon Dr Suryakanta Narendra, he stated. (Newindpress)

    More on Motrin and Stevens-Johnson syndrome  Jul 19, 2008
    Here's the beginning of an account from the family who launched the : "Julie was 10 months old when she had a grand mal seizure. She was prescribed Phenobarbital to control idiopathic epilepsy. ... Julie awoke one morning with her right eye swollen shut. By that evening her left eye swelled also and the right one was now completely shut. My mother thought the baby had an allergy." The story continues from there -- and it's wrenching. Julie is now a teenager, blind in one eye, who has launched... (Los Angeles Times)

    Gene That Regulates And Blocks Ovulation Discovered  Jul 18, 2008
    1, 2006) For about one in 10 couples that cannot conceive a child, their reproductive problem falls under the broad category of "idiopathic infertility," meaning the cause remains to be determined. But these. (Science Daily)

    Finding a New Heart for a Toddler  Jul 18, 2008
    A team of pediatricians diagnosed Peyton with idiopathic cardio myopathy -- heart inflammation with no known cause. The pediatricians came to a bleak conclusion: Peyton needed a heart transplant, or he would die. (ABC News)

    Custom-Made Insoles Can Reduce Foot Pain  Jul 16, 2008
    Researchers found that custom foot orthoses can relieve pain within three months in adults with rheumatoid arthritis, as well as in children with juvenile idiopathic arthritis, an early onset form of the disease. Adults with painful highly arched feet or painfully prominent big toe joints also benefited from treatment with orthoses over three and six month periods respectively. (Newsmax)

    Clinicians Should Consider Economic Impact Of New Interventions, According To New Report  Jul 7, 2008
    1, 2007) A new study examined direct medical costs of children with juvenile idiopathic arthritis and found that the economic impact was. (May 12, 2008) Public investment in early childhood programs may be able to lower public costs for social services by improving children's long-term welfare. (Science Daily)

    Pain Beyond Words  Jul 7, 2008
    She was diagnosed with chronic idiopathic demyelinating polyradiculoneuropathya disease in which rogue antibodies present in one's blood plasma attack the myelin sheath, the protective and connective covering of one's nerves. For four years, Manguso suffered numerous episodes of escalating paralysis that could be reversed only through an arduous process called apherisis: Her veins were drained of the offending plasma and infused with new. (Slate)

    Pediatric researchers find possible 'master switch' gene in juvenile arthritis  Jul 2, 2008
    Researchers at The Children's Hospital of Philadelphia reported on the link between the gene region and juvenile idiopathic arthritis (JIA), formerly called juvenile rheumatoid arthritis. The genetic variant is on chromosome 9 in a region housing two genes, TRAF1 and C5. (EurekAlert!)

    FDA Panel OKs Enbrel for Psoriasis in Children  Jun 20, 2008
    It was first approved by the FDA in 1999 to treat in adults; the FDA later approved it to treat certain other arthritic conditions, including , which is now called juvenile idiopathic , in patients aged 2 and older. Enbrel's Clinical Trial. (WebMD)

    EpiPen(R) Partners with Lucy Waverman, Canadian Culinary Personality, to Offer Fresh, Natural Recipes for People Who Suffer from Life-Threatening Allergies  Jun 17, 2008
    Such emergencies may occur spontaneously or from insect stings, bites, foods, drugs, or other allergens, as well as idiopathic or exercise induced anaphylaxis. How Supplied: EpiPen and EpiPen Jr. auto-injectors are available in single cartons. (Canada Newswire)

    U.S. FDA Approves Requip(R) XL(TM), the First and Only Oral Once-Daily Non-Ergot Dopamine Agonist for Parkinson's Disease  Jun 14, 2008
    Requip XL Improved Symptoms in Patients Not Optimally Controlled with Levodopa and Reduced Patients' "Off" Time by Nearly Two Hours Per Day RESEARCH TRIANGLE PARK, N.C., June 13 /PRNewswire-FirstCall/ -- GlaxoSmithKline (NYSE: ) today announced the approval of Requip(R) XL(TM) (ropinirole extended-release tablets) in the U.S. for the treatment of the signs and symptoms of idiopathic Parkinson's disease ... Clinical Study FDA approval was based primarily on results from the EASE-PD (Efficacy And... (PR Newswire)

    Data Show that Abbott's HUMIRA(R) (adalimumab) Reduced the Signs and Symptoms of Ankylosing Spondylitis Up to Three Years  Jun 13, 2008
    In the United States, HUMIRA is also approved for the treatment of juvenile idiopathic arthritis (JIA). HUMIRA is indicated for the treatment of active and progressive psoriatic arthritis in adults when the response to previous disease-modifying anti-rheumatic drug therapy has been inadequate. (Canada Newswire)

    XOMA 052 Demonstrates Anti-Inflammatory Effects in Diabetes Animal Studies; Data Presented At ADA  Jun 8, 2008
    In 2008, XOMA plans to initiate clinical studies of XOMA 052 in rheumatoid arthritis, acute gout, and systemic juvenile idiopathic arthritis (sJIA) ... These disease indications include rheumatoid arthritis, systemic juvenile idiopathic arthritis, gout, Muckle-Wells syndrome and others. (Primezone Releases)

    Neuromyelitis Optica  Jun 5, 2008
    Devic's Syndrome: Multiple Sclerosis Variant Often Confused with MS. NMO antibodies are key to diagnosis. (Suite101.com)

    Abbott drugs in FDA risk reviews  Jun 5, 2008
    "The drugs Enbrel, Humira, and Remicade are being reviewed for a possible association between their use and the development of lymphoma and other cancers in children and young adults treated with TNF blockers for juvenile idiopathic arthritis and Crohn's disease," the FDA said. "Lymphoma is a cancer of the cells in the immune system.". (Chicago Tribune)

    FDA panel favors Glaxo, Ligand blood drug  May 31, 2008
    British drugmaker Glaxo and partner Ligand want Promacta approved to treat patients' with chronic idiopathic thrombocytopenic purpura, which causes excessive bruising and bleeding. About 60,000 people in the U.S. have the disease, according to Glaxo. (USA Today)

    Hormone May Hold Key To Helping Elderly Men Live Longer  May 29, 2008
    7, 2005) A randomized UCLA study found that a new dosing paradigm can improve height outcomes in the treatment of children who have short stature due to growth hormone deficiency and idiopathic short. (Apr. (Science Daily)

    Supreme Court Chief Taken to Hospital After Fall  May 29, 2008
    Roberts, 52, fell on a dock after having a "benign idiopathic seizure," said Kathleen Landin Arberg, the court's public information officer ... Arberg's description of a benign idiopathic seizure indicates an episode whose origins are unknown. (Yahoo News -- Supreme Court)

    AMITIZA 8 mcg now available to treat irritable bowel syndrome  May 28, 2008
    AMITIZA 24 mcg capsules have been available by prescription to treat Chronic Idiopathic Constipation in adults since 2006 ... AMITIZA has a mechanism of action that works locally in the intestine to increase fluid secretion, resulting in increased passage of stool and alleviating symptoms associated with Chronic Idiopathic Constipation ... About AMITIZA (lubiprostone) for Chronic Idiopathic Constipation and IBS-C. (EurekAlert! -- Business News)

    New Treatment Gives Hope For Pulmonary Fibrosis Patients  May 24, 2008
    ScienceDaily (May 23, 2008) Patients with idiopathic pulmonary fibrosis (IPF) may have a new treatment option, according to researchers in Japan ... 24, 2005) Every breath soon turns into a struggle for people living with idiopathic pulmonary fibrosis (IPF) ... 9, 2005) A lung disease known as idiopathic pulmonary fibrosis strikes without warning and often kills within only a few years. (Science Daily)

    Drug for Deadly Lung Disease Shows Promise  May 23, 2008
    Idiopathic pulmonary fibrosis kills 40,000 Americans each year ... Japanese researchers say daily use of the drug pirfenidone improved the lung function and lengthened the survival of patients with the illness, called idiopathic pulmonary fibrosis (IPF). (Health-Finder)

    Oxidative Stress May Predict Later Lung Trouble In Young Adults  May 23, 2008
    1, 2007) Reasearchers have announced a potential breakthrough in the treatment of idiopathic pulmonary hemosiderosis, a rare condition which can affect children and young. (Mar. (Science Daily)

    Drug Brings Relief For Many IBS Patients Who Experience Constipation  May 21, 2008
    The supplemental New Drug Application for AMITIZA -- which also is approved by the FDA for treatment of chronic idiopathic constipation -- was based on two phase III, multi-center trials involving 1,154 participants. These trials compared lubiprostone versus a placebo during the course of 12 weeks. (Science Daily)

    Drug Brings Relief for IBS Patients  May 20, 2008
    On a Handheld Device. SIGN UP FOR FREE NEWS ALERTS. (Newsmax)

    Walking again'My arthritis left me needing two new hips by the age of 22'  May 17, 2008
    Despite having had the condition, a rare form of the disease called juvenile idiopathic arthritis, since she was five, Natalie felt well enough to start her university course and her first year went as planned. Missed days. (BBC News -- UK)

    Trigeminal Neuritis in the Dog  May 10, 2008
    Any trauma or damage to the trigeminal nerve be it from an impact or injury or from a tumor can lead to TN, but in a significant portion of canine cases, this is an idiopathic condition where the precise cause is unknown, explained Dr. Michael Levine, DVM, a practicing veterinarian and professor of veterinary medicine. Due to its rarity, TN is most often diagnosed following an examination by a veterinary neurologist. (Suite101.com)

    New Study Demonstrates ACTEMRA(R) (tocilizumab) Inhibits Progression of Joint Damage in Rheumatoid Arthritis Patients  May 9, 2008
    In April 2005, ACTEMRA was launched by Chugai in Japan as a therapy for Castleman's disease; in April 2008, ACTEMRA was approved for the treatment of rheumatoid arthritis, juvenile idiopathic arthritis and systemic-onset juvenile idiopathic arthritis in Japan. The serious adverse events reported in ACTEMRA clinical trials were serious infections and hypersensitivity reactions including anaphylaxis. (PR Newswire)

    Augmentation of J Waves and Electrical Storms in Patients with Early Repolarization  May 8, 2008
    2 Sporadic case reports and basic electrophysiological research have suggested a critical role of the J wave in the pathogenesis of idiopathic ventricular fibrillation. 3,4 Clinical evidence in support of an. (New England Journal of Medicine)

    Sudden Cardiac Arrest and Early Repolarization  May 8, 2008
    Methods We reviewed data from 206 case subjects at 22 centers who were resuscitated after cardiac arrest due to idiopathic ventricular fibrillation and assessed the prevalence of electrocardiographic early repolarization ... Results Early repolarization was more frequent in case subjects with idiopathic ventricular fibrillation than in control subjects (31% vs. 5%, P<0 ... Conclusions Among patients with a history of idiopathic ventricular fibrillation, there is an increased prevalence of early... (New England Journal of Medicine)

    Little steps, big change  May 7, 2008
    She was diagnosed with idiopathic gastroparesis, a rare disorder in which, basically, the stomach doesn't work. She was dehydrated and had been vomiting and enduring severe pain. (Albany Times Union)

    Scientists identify genomic 'fingerprint' for alcohol-induced heart failure  May 5, 2008
    While clinicians know that up to 36 percent of all cases of dilated cardiomyopathy may be due to excessive drinking, it has been difficult to differentiate between alcohol-induced heart failure and heart failure due to idiopathic dilated cardiomyopathy ... The etiology of alcohol-induced cardiomyopathy is unique and different from other forms of cardiomyopathy, especially the idiopathic dilated cardiomyopathy, said Gwathmey. (EurekAlert!)

    FDA approves irritable bowel drug  May 2, 2008
    Amitiza is already approved for the treatment of chronic idiopathic constipation at 24 micrograms twice a day, much higher than the 8 micrograms twice a day recommended for treatment of IBS-C.. The FDA, in its statement, described both Takeda and Sucampo as manufacturers of Amitiza but a spokesman for Sucampo said that while both companies market the drug, Sucampo was the developer. (MSNBC -- Health)

    Cause of Childhood-Onset Cardiac Hypertrophy  May 2, 2008
    Background The childhood onset of idiopathic cardiac hypertrophy that occurs without a family history of cardiomyopathy can portend a poor prognosis ... Methods We assessed the family and medical histories of 84 children (63 boys and 21 girls) with idiopathic cardiac hypertrophy diagnosed before 15 years of age (mean [ SD] age, 6. (New England Journal of Medicine)

    Growth Hormone Is Used To Treat Twice As Many Short Boys Than Girls In The US And Asia  Apr 21, 2008
    The greatest gender disparities occurred for diagnoses without an identifiable cause, such as idiopathic short stature and idiopathic GH deficiency because of the complexity of the diagnostic tests ... Prior to 1985, only children with the most severe growth hormone deficiency were treated because of the very limited supply of human pituitary GH. In 2003, the U.S. Food & Drug Administration (FDA) approved the use of rhGH for the treatment of idiopathic short stature, for children who are... (Science Daily)

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