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News and Articles on Gene-expression profiling
Genetic Key To Breast Cancer's Ability To Survive And Spread Identified Jul 10, 2009 Using gene-expression profiling techniques, researchers found that breast cancer cells that infiltrate the bone marrow can survive over time if they contain the gene product Src, which has known effects on cell mobility, invasion, and survival. The investigators discovered that genetically disabling Src activity in human breast cancer cells inhibits these cells from surviving in the bone marrow and forming metastases in mice. (Science Daily)
GEN highlights increasing use of digital gene expression profiling Apr 4, 2009 New Rochelle, NY, April 3, 2009A novel technique for carrying out gene-expression profiling is set to challenge the market dominance of the current, widely used methodology, reports Genetic Engineering chnology News (GEN). Some scientists believe that digital gene-expression profiling, a fully quantitative approach for gene-expression analysis, will eventually rival microarrays in this application area, according to the April 1 issue of GEN (). (EurekAlert!)
Gene-Expression Signatures in Breast Cancer Feb 19, 2009 Christos Sotiriou, M.D., D.Phil. and Lajos Pusztai, M.D., D.Phil. (New England Journal of Medicine)
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