Aspirin use in people with diabetes Oct 20, 2008
Although no significant difference was seen in the rate of gastrointestinal bleeding between each group, there was a trend for a greater incidence of gastrointestinal symptoms, including indigestion, in patients given aspirin. Between 27% and 33% of participants were smokers, and this may explain why these people were at high risk for the primary events - there was about a 3% risk of an event for each year of the study. (NHS Choices)
Aspirin No Help for Diabetics' Heart Risk Oct 19, 2008
Aspirin is known to cause ulcers and bleeding in the stomach, and is one of the most common causes for hospitalization for gastrointestinal bleeding in Scotland, she says. Professor Peter Sever, an expert in clinical pharmacology at Imperial College London, says he has had several patients admitted to the hospital for severe bleeding, and that he routinely advises patients who have not had heart attacks to stop popping the pill. (Time.com)
Aspirin heart benefit questioned Oct 17, 2008
Study leader Professor Jill Belch, from the University of Dundee, said aspirin was one of the most common causes of hospital admission for gastrointestinal bleeding ... "Thousands of people buy aspirin over the counter - I'm forever saying to patients you shouldn't be taking this. "I have had a couple of patients admitted to hospital with major gastrointestinal bleeding when there was no evidence it was doing any good. (BBC News)
Aspirin Doesnt Prevent Heart Attack in Diabetics Oct 17, 2008
It causes gastrointestinal bleeding and the risk of bleeding increases with age and prolonged use. Professor Jill Belch and colleagues from Scotland investigated whether aspirin and antioxidants given together or separately can reduce heart attacks and death in patients with diabetes and arterial disease. (Newsmax)
Gastroesophageal Reflux Disease Oct 16, 2008
He reports having had no dysphagia, gastrointestinal bleeding, or weight loss and in fact has recently gained 20 lb (9 kg). What would you advise regarding his evaluation and treatment. (New England Journal of Medicine)
Study Confirms Vioxx Doubles Heart Risks Oct 14, 2008
Cox-2 drugs were designed to be safer replacements for NSAIDS, including aspirin and naproxen, which can cause deadly gastrointestinal bleeding. "There seems to be an increased risk for most if not all non-steroidal anti-inflammatory drugs. That doesn't mean these aren't good drugs. It's just there is some increased risk we need to be aware of," he said. (Newsmax)
Doctors' Groups Collaborate on Care for Heart Patients Oct 11, 2008
THURSDAY, Oct. 9 (HealthDay News) -- Three leading medical associations have created guidelines to help heart disease patients cut their risk of ulcers and gastrointestinal bleeding from the condition's most common treatments -- antiplatelets and nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin ... Having several of these risk factors greatly increases the person's chance of gastrointestinal bleeding, a major and potentially life-threatening complication ... People on low-dose... (MEDLINEplus)
Aspirin may cut breast cancer risk Oct 10, 2008
Prolonged use of these medications can cause serious side effects such as gastrointestinal bleeding. But the findings could eventually lead to new prevention options, she said. (Globe and Mail)
A new breakthrough in timing of urgent endoscopy for gastrointestinal bleeding patients Sep 10, 2008
Public release date: 10-Sep-2008. It is widely accepted that urgent endoscopy for UGIB should be performed within 24 hour from the admission. (EurekAlert!)
Older People in Danger from Common Drugs Aug 28, 2008
Naproxen (Aleve) can cause gastrointestinal bleeding and damage the kidneys. Substitutes may include acetaminophen (Tylenol) and ibuprofen (Advil). (Newsmax)
Study Commences at Henry Ford Hospital to Examine Efficacy of Ivivi tPEMF Technology to Relieve Pain From Knee Osteoarthritis Aug 25, 2008
Osteoarthritis is marked by various degrees of inflammation and according to the American Heart Association, current therapies such as common NSAID-based pain relievers can increase the risk of heart failure, stroke, hypertension and gastrointestinal bleeding in some patients. The technology could fit well with our collaborative multi-disciplinary approach to orthopaedic and rehabilitative conditions and we believe it holds promise not only for patients with osteoarthritis, but also in post... (Primezone Releases)
Accutane Case Before 11th Circuit Centers on Expert Witness Aug 21, 2008
Schmidt said the dogs' gastrointestinal bleeding subsided once Accutane was no longer administered -- and the defendants contrast that with IBD, which humans can experience as a permanent condition. Human case studies on which the expert relied merely raise questions and are not controlled experiments, he said. (Law.com)
Doctors say Merck study a ploy Aug 19, 2008
Both makers claimed their drugs caused less cramping, diarrhea and dangerous gastrointestinal bleeding than other pain relievers. Dr. Hill, now a staff psychiatrist at McLean Hospital in Massachusetts, said he and his colleagues found documents indicating "ADVANTAGE was marketing framed as scientific research.". (The Augusta Chronicle)
Long-Term Acid Reflux Therapy Can Be Cost-Effective Aug 14, 2008
NEW YORK (Reuters Health) - In patients taking aspirin to lower their risk of having a heart attack or stroke, lifelong therapy with a proton pump inhibitor (PPI), which includes drugs such as Nexium or Prilosec, can be a cost-effective means of reducing the risk of upper gastrointestinal bleeding, according to a report in the Archives of Internal Medicine. For patients with a high risk of gastrointestinal bleeding, this treatment is nearly always cost effective, the report indicates ... The... (MEDLINEplus)
Powerful Antacid Drugs Raise Fracture Risk Aug 13, 2008
Aspirin carries a risk for upper gastrointestinal bleeding. Adding PPIs may also be cost-effective for patients down to the age of 50. (MEDLINEplus)
Combining Aspirin With Acid Blocker Reduces Bleeding Aug 13, 2008
For patients with clogged heart arteries who take long-term, low-dose aspirin to prevent a cardiac event, adding a stomach acid-blocking drug to their daily routine has been shown to reduce their risk for upper gastrointestinal bleeding an infrequent, but serious side-effect of regular aspirin use ... Regular use of asprin, however, poses a small risk for upper gastrointestinal bleeding. (Newsmax)
Jazz owner out of hospital after two-month stay Aug 9, 2008
His condition was complicated by Type 2 diabetes and the most recent scare came from gastrointestinal bleeding that required two operations. Miller needs a wheelchair but he hopes to regain the use of his legs, which he said lost their strength during the hospital stay. (SportsIllustrated.CNN -- NBA)
NEWS IN BRIEF Aug 9, 2008
His condition was complicated by Type 2 diabetes and the most recent scare came from gastrointestinal bleeding that required two operations. --- GOLF. (Nola.com -- Sports)
Vioxx, Bextra Linked to Increased Stroke Risk Aug 9, 2008
"Since all NSAIDs, including coxibs, can raise blood pressure and increase the risk of gastrointestinal bleeding, we believe that caution is warranted, especially with long-term use of these medicines.". SOURCE: Stroke, July 2008. (MEDLINEplus)
Gastrointestinal bleeding after stroke may increase risk of death Aug 8, 2008
"This is an important finding since there are effective medications to reduce gastric acid that can lead to upper gastrointestinal bleeding," said study author Martin O'Donnell, MB, of McMaster University in Hamilton, Ontario ... 5 percent, had gastrointestinal bleeding, or bleeding in the stomach or intestines, while they were in the hospital from the stroke. (Hindu)
GI Bleeding After Stroke Raises Death Risk Aug 8, 2008
WEDNESDAY, Aug. 6 (HealthDay News) -- Stroke patients who develop gastrointestinal bleeding while in recovery are three times as likely to die in the hospital or be heavily disabled upon release than those who do not, a new Canadian study suggests ... "And as part of that larger observation, we know that among these complications are GI issues. And we feel that this is particularly important, because gastrointestinal bleeding is a complication that is potentially modifiable with various... (MEDLINEplus)
Gastrointestinal bleeding after stroke may be fatal Aug 7, 2008
"This is an important finding since there are effective medications to reduce gastric acid that can lead to upper gastrointestinal bleeding," said study author Martin O'Donnell from Canada's McMaster University. "More research will be needed to determine whether this is a viable strategy to improve outcomes after stroke in high-risk patients.". (Hindu)
Why is My Pet Vomiting Blood? Jul 28, 2008
Medications such as certain anti-inflammatory medications can cause gastrointestinal bleeding, therefore discontinuation of the medication is often required to allow for proper healing. Related Reading. (Suite101.com)
Women Turning to Internet for Risky At-Home Abortions Jul 13, 2008
Mifepristone is sold in the U.S. as RU-486 and misoprostol is sold as Cytotec and is commonly used for the prevention of gastrointestinal bleeding in the U.S.. The site says ingesting a combination of pills containing these two ingredients causes the non-surgical termination of a pregnancy and can be used up to the ninth week of pregnancy. (Fox News)
Antidepressants tied to gastrointestinal bleeding Jul 8, 2008
WASHINGTON (Reuters) - A class of drugs used by many people to treat depression may increase chances of gastrointestinal bleeding, although the risk remains low, Spanish researchers said on Monday ... Such risk factors for gastrointestinal bleeding include a peptic ulcer or being elderly, he said. (Reuters India)
Drugs Doctors Wont Take And Neither Should You Jun 24, 2008
In addition, Celebrex is linked to liver damage, kidney problems, and gastrointestinal bleeding. Although nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen could be safer alternatives, they, too, have been liked to intestinal bleeding. (Newsmax)
8 drugs doctors wouldn't take Jun 23, 2008
Your new strategy: What you don't want to do is stop swallowing Celebrex and begin knocking back ibuprofen, because regular use of high doses of nonsteroidal anti-inflammatory drugs (NSAIDs) can lead to gastrointestinal bleeding. A safer swap is acupuncture. (MSNBC -- Health)
Aspirin May Help Prevent Asthma in Women Jun 17, 2008
In an editorial published with the study, Dr. Andrew A. Clayton and colleagues at the Centre for Respiratory Research in Nottingham, UK, point out that women in the aspirin group had a significantly increased risk of gastrointestinal bleeding requiring blood transfusion. "It is debatable," they say, "whether such a risk is acceptable in order to achieve the reduction in asthma risk.". (MEDLINEplus)
Anti-Inflammatory Drugs Efficient in Preventing Alzheimers May 30, 2008
They can cause serious gastrointestinal bleeding. Therefore, Dr. Zandi did not recommend permanent use of NSAIDs just to prevent Alzheimers disease. (eFluxMedia)
Study: Older brains don't benefit from painkillers May 15, 2008
Anti-inflammatory drugs also can cause serious gastrointestinal bleeding. Experts advise patients to ask their doctors about how long to take the drugs for pain. (Chippewa Falls Chippewa Herald, WI)
Your Health This Week May 14, 2008
In short, the same medication that might well help prevent Alzheimer's can increase the risk of disastrous gastrointestinal bleeding and of heart attacks, strokes, and kidney damage. Conclusion: What to do. (Slate)
Painkillers don't slow dementia, study says May 13, 2008
"With the side effects of these drugs, people shouldn't be taking them for this reason.''Both products now carry warnings about heart risks. Anti-inflammatory drugs also can cause serious gastrointestinal bleeding. Experts advise patients to ask their doctors about how long to take the drugs for pain.Click for related contentThe study was funded by the National Institute on Aging. Pfizer Inc. and Bayer Healthcare provided the drugs and matching dummy pills for the study, but did not... (MSNBC -- Health)
Studies rarely reveal researchers' links to stent companies May 11, 2008
Ibuprofen, sold under a variety of brand names such as Advil and Motrin, can cause serious side effects including gastrointestinal bleeding. "Using ibuprofen for [Alzheimer's disease] protection is premature at this point and could cause more harm than good," lead researcher Steven Vlad at Boston University's school of medicine, said in an e-mail. (Globe and Mail)
Steroids Provide No Survival Benefit for Children With Bacterial Meningitis May 7, 2008
"This study reminds us again that children are not just small adults. We need to consider whether the problems associated with corticosteroid use, such as gastrointestinal bleeding, outweigh any potential benefits." He added that further research should analyze whether corticosteroids may provide other benefits to children, such as improved neurological outcomes among survivors, a question not considered in this study. The study appears in the May 7 issue of the Journal of the American Medical... (PR Newswire)
Ibuprofen Lowers Risk of Alzheimers May 6, 2008
"All NSAIDs have significant risks including ulcers, gastrointestinal bleeding, kidney dysfunction, elevated blood pressure and, certainly in the case of COX-II inhibitors like (Merck Inc's withdrawn drug) Vioxx, a cardiovascular risk," he said. "I think the major implications of this study are more in the direction of prompting further research: a trial of ibuprofen to prevent Alzheimer's disease might be reasonable," he said. (Newsmax)
Daily Aspirin May Reduce Breast Cancer Risk May 2, 2008
"The American Cancer Society does not recommend using aspirin for cancer prevention because aspirin can cause serious gastrointestinal bleeding," said Eric J. Jacobs, Strategic Director of Pharmacoepidemiology in the department of epidemiology and surveillance research at the American Cancer Society ... "This decision should be based on balancing the proven benefits of aspirin in preventing heart disease against the proven risks of serious gastrointestinal bleeding," he said. (Atlanta Journal Constitution)
Cows, rats and you: How a dairy farmer's scourge led to a widely used medicine, and why everyone is trying to get rid of it Apr 23, 2008
It is often said that aspirin wouldn t pass government muster these days because of the risk of gastrointestinal bleeding, said Dr. Gurvaneet Randhawa, a senior advisor on personalized medicine and genomics at the federal Agency for Healthcare Research and Quality. For a few million dollars, researchers can screen substances such as tick saliva for anticoagulants, Moliterno said. (Racine Journal Times, WI)
Rebleeding rate after interventional therapy directed by capsule endoscopy in patients with obscure gastrointestinal bleeding Apr 23, 2008
The precise role of capsule endoscopy in the diagnostic algorithm of obscure gastrointestinal bleeding has yet to be determined ... The aim of this study was to evaluate the follow-up results of patients with obscure gastrointestinal bleeding to determine which management strategies after capsule endoscopy reduced rebleeding ... All patients in whom the cause of obscure gastrointestinal bleeding was investigated between May 2004 and March 2007 were studied retrospectively. (BioMed Central)
Your Health: Herbal extract may provide effective alternative to aspirin Apr 18, 2008
Although aspirin is generally safe and well-tolerated by healthy individuals in the recommended doses, its use can produce a number of unpleasant side effects, including: stomach upset and ulceration, gastrointestinal bleeding and ringing in the ears. For centuries, extracts from the bark and leaves of the white willow tree have been used to relieve pain and reduce fever. (Green Valley News & Sun, AZ)
Treximet(TM) (Sumatriptan and Naproxen Sodium) Tablets Approved by FDA for Acute Treatment of Migraine Apr 16, 2008
NSAID-containing products, including Treximet, should be prescribed with extreme caution in those with a prior history of ulcer disease or gastrointestinal bleeding. Treximet should not be used in late pregnancy because NSAID-containing products have been shown to cause premature closure of the ductus arteriosus. (PR Newswire)
Protecting A Life-saving Blood Product From Human Form Of Mad Cow Disease Apr 13, 2008
Transfusions of red blood cells go to thousands of patients with chronic anemia resulting from kidney failure, cancer, gastrointestinal bleeding, and acute blood loss resulting from trauma. The researchers needed five years to develop the device and are now working on ways to remove prion proteins from other blood components, including plasma and plasma proteins, Gurgel said. (Science Daily)
Study: Cod Liver Oil Helps Battle Arthritis Mar 25, 2008
But in high doses these have been linked to side-effects including increased risk of heart attacks, strokes and gastrointestinal bleeding. Doses given for conditions like arthritis are much higher than for people who use the drugs as occasional painkillers. (Sky News)
New Rheumatoid Arthritis Drug Works for Adults, Children Mar 22, 2008
Side effects included gastrointestinal bleeding, bronchitis, and gastroenteritis. "The results of this placebo-controlled and open-label extension study with tocilizumab in children with systemic-onset juvenile idiopathic arthritis show a sustained clinical improvement and a favorable risk-benefit profile," the Japanese team wrote. (MEDLINEplus)
Children Of Alcoholics: Different Brain Regions Effect Who May Or May Not Develop Alcohol Problems Mar 8, 2008
18, 2008) Gastrointestinal bleeding can be fatal -- something which is not known to many alcoholics. More than 400 patients from the major German cities of Leipzig and Munich were included in the study. (Science Daily)
Aspirin Could Reduce Breast Cancer And Help Existing Sufferers, Review of Studies Suggests Mar 8, 2008
" Previous studies have suggested that NSAIDs like aspirin and ibuprofen, which have traditionally been used as mainstream non-prescription analgesics, may provide protection against coronary heart disease and some malignancies, such as colorectal cancer. But Professor Fentiman is urging caution until further research fully weighs up the pros and cons of using NSAIDs to prevent and treat breast cancer. "Our review did not look at the potential side effects of using NSAIDs on a regular basis"... (Science Daily)
Aspirin May Prevent and Treat Breast Cancer Mar 7, 2008
Our review did not look at the potential side effects of using NSAIDs on a regular basis stresses Professor Fentiman These can include gastrointestinal bleeding and perforation which can carry a significant risk of ill health and death. It would be essential to take these negative effects into account before we could justify routinely using NSAIDs like aspirin to prevent breast cancer. (Newsmax)
A strange case of upper obstructive syndrome Feb 23, 2008
Aorto-duodenal fistulae (ADF) are the most frequent aorto-enteric fistulae (80%) and the most frequent presenting sign of ADF is upper gastrointestinal bleeding (UGI). A 59-year-old male patient, who underwent an aortic-bi-femoral bypass five years ago, was admitted to the Emergency Room after five days of persistent occlusive syndrome with dyspepsia and biliary vomiting. (EurekAlert!)
Alcoholics underestimate the risk of bleeding Feb 19, 2008
Gastrointestinal bleeding can be fatal - something which is not known to many alcoholics. This was the conclusion reached by the Leipzig gastroenterologist Niels Teich and his colleagues, on the basis of a survey in the current edition of Deutsches rzteblatt International (Dtsch Arztebl Int 2008; 105[5]: 73-7). (EurekAlert!)
Symptoms: Metabolic syndrome is tied to diet soda Feb 7, 2008
Still, he said, "I wouldn't recommend it to all patients, because of the side effects," which can range from upset stomach to gastrointestinal bleeding. The study appears in the January issue of Gastroenterology. (International Herald Tribune)
Top-Rated Hospitals Continue to Deliver Better Care Feb 1, 2008
The procedures and diagnoses included in the analysis included: cardiac surgery; angioplasty and stenting; heart attack; heart failure; atrial fibrillation; chronic obstructive pulmonary disease; community-acquired pneumonia; stroke; abdominal aortic aneurysm repair; bowel obstruction; gastrointestinal bleeding; pancreatitis; diabetic acidosis and coma; pulmonary embolism; and sepsis. Dr. Samantha Collier, HealthGrades chief medical officer, said, "The data in this year's study clearly indicates... (Health-Finder)
Regular, Long-term Aspirin Use Reduces Risk Of Colorectal Cancer, Study Suggests Jan 24, 2008
However, the use of aspirin for chemoprevention of colorectal cancer may require using the drug at doses that are higher than recommended over a long period of time, which may cause serious side effects including gastrointestinal bleeding. See also. (Science Daily)
Is An Aspirin A Day Good For You? Jan 14, 2008
The study, which was published in the Journal of the American Medical Association, found that doses higher than a baby aspirin, 75 to 81 mg, are no better at preventing cardiovascular events long-term and are associated with increased risk of gastrointestinal bleeding. Gill Heart Institute cardiologists and University of Kentucky College of Medicine faculty Dr. Charles Campbell, Dr. Steven R. Steinhubl and Dr. Susan Smyth, along with Dr. Gilles Montalescot of the Instjtut de Cardiologie-Centre... (Science Daily)
Five easy ways to get, stay healthy Dec 31, 2007
And be aware that aspirin has some serious risks, including gastrointestinal bleeding. Copyright 2007 Globe Newspaper Company. (Boston Globe)
Allergy to medicines 'is killing thousands' Dec 27, 2007
The most common problem associated with these medications is gastrointestinal bleeding, which can be fatal. But many of the reactions were likely to be because of incorrect dosages or known interactions of the drugs and as such were avoidable, research suggests. (Times Online)
Cystic Fibrosis: Ibuprofen Associated With Slower Lung Function Decline In Children, Study Suggests Dec 5, 2007
The study concluded that the benefits of ibuprofen therapy outweigh the small risk of gastrointestinal bleeding ... Dr. Konstan led a clinical trial 12 years ago that found ibuprofen reduced the loss of lung function in CF patients, but questions have remained about the safety of regular high-dose ibuprofen use, which in some cases can lead to gastrointestinal bleeding ... This study showed that gastrointestinal bleeding was rare, with an annual incidence of 0. (Science Daily)
Ibuprofen Preserves Lung Function in Kids With Cystic Fibrosis Dec 1, 2007
Part of the reluctance to use ibuprofen is the fear on the part of doctors of increased gastrointestinal bleeding, a common side effect with ibuprofen and other anti-inflammatory drugs, Konstan explained ... In the new study, which appears in the December issue of American Journal of Respiratory and Critical Care Medicine, Konstan's team was able to show that the risk of gastrointestinal bleeding was small while the benefit was significant ... Moreover, gastrointestinal bleeding was rare, with... (Health-Finder)
FDA Approves New SPRYCEL(R) (Dasatinib) Product Labeling for Patients with Chronic-Phase CML Nov 9, 2007
The study supports the new recommended starting dose, 100 mg once daily, for chronic-phase CML. Incidence of selected adverse reactions (all grades) in the Phase 3 dose- optimization study in chronic-phase CML patients receiving SPRYCEL 100 mg once daily (n=165) or SPRYCEL 70 mg twice daily (n=167) included diarrhea (23%, 25%); fluid retention events (24%, 32%) such as superficial edema (14%, 16%), pleural effusion (10%, 18%), generalized edema (2%, 1%), congestive heart failure/cardiac... (PR Newswire)
Study: New heart pill beats Plavix Nov 4, 2007
This included brain or gastrointestinal bleeding, or after falls. Fatal bleeding was uncommon, but four times more frequent with the new drug. (Brainerd Daily Dispatch)
Commanding yet isolated, Suharto fades away Nov 1, 2007
President Susilo Bambang Yudhoyono, who was a rising general in Suharto's military-dominated government, still refers to him as "my senior" and visited him in the hospital in 2005 when he had severe gastrointestinal bleeding. Many of those who grew wealthy through their connections with him remain among the country's richest people. (International Herald Tribune)
Video 'Pill' Spots Hidden Crohn's Disease Oct 23, 2007
A team at Wake Forest University Baptist Medical Center, in Winston-Salem, N.C., performed 198 video capsule endoscopies to evaluate unexplained gastrointestinal bleeding in patients. Using the capsules, the researchers identified six cases of undiagnosed Crohn's disease in patients who'd had colonoscopies and other types of tests. (MEDLINEplus)
Capsule Endoscopy Turning Up Undiagnosed Cases Of Crohn's Disease Oct 18, 2007
Reporting this week at the American College of Gastroenterology's meeting in Philadelphia, the researchers said that of 198 video capsule endoscopies that were performed to evaluate unexplained gastrointestinal bleeding, physicians found six cases of Crohn's disease that hadn't been diagnosed previously, despite the patients having colonoscopies and a variety of other imaging tests ... "This study suggests the importance of using capsule endoscopy to fully evaluate people with unexplained... (Science Daily)
Risks And Health-care Costs Of Common Pain Killers Underestimated Oct 17, 2007
Ulcers and gastrointestinal bleeding are serious health problems in the United States. With millions taking NSAID pain medications every day, it is estimated that more than 100,000 Americans are hospitalized each year and between 15,000 and 20,000 Americans die each year from ulcers and gastrointestinal bleeding linked to NSAID use. (Science Daily)
Many Patients Don't Report Use of Over-the-Counter Pain Drugs Oct 17, 2007
Gastrointestinal bleeding, which can be caused by ulcers that perforate the stomach wall, occurs in an estimated 4. 5 percent of patients who take these painkillers over the long term. (MEDLINEplus)
Antidepressants Boost Gastrointestinal Bleeding Risk Oct 16, 2007
FRIDAY, Oct. 12 (HealthDay News) -- Antidepressant drugs called selective serotonin reuptake inhibitors (SSRIs), which include Celexa, Paxil, Prozac and Zoloft, can double the risk of gastrointestinal bleeding, and the threat is more than six times higher if patients take aspirin and similar pain medications at the same time as SSRIs, a new study finds. "Clinicians who prescribe these medications should be aware of the potential risk and may need to consider alternatives," senior researcher Dr.... (MEDLINEplus)
Our policy makers neither understand, nor care much about climate change. Oct 10, 2007
Also, nearly one-fourth of the people in neighbouring villagers are suffering from pollution-induced diseases, which include gastrointestinal bleeding, tuberculosis, asthma, infertility, birth defects and stillbirths. Vapi houses more than 50 industrial estates and over 1,000 independent industries. (India Times, India)