UCR researchers propose minocycline as a promising drug for patients with Fragile X syndrome Oct 4, 2008
Study leader Iryna Ethell awarded FRAXA Breakthrough Award for 2008 ... The study was funded by a grant from the FRAXA Research Foundation ... Dr. Michael Tranfaglia, FRAXA's chief scientific officer, said of the UCR researchers, "This group has done something unique and incredibly valuable: They have identified an off-the-shelf treatment for Fragile X through their basic research. By bringing their unique perspective to Fragile X research, they have helped us to understand why neurons are... (EurekAlert!)
Lack Of Fragile X And Related Gene Fractures Sleep Jun 28, 2008
Funding for this work came from the U.S. National Institute of Child Health and Human Development, the BCM Mental Retardation and Developmental Disability Research Center, the Fragile X Research (FRAXA) Foundation, the Swiss National Science Foundation and EUCLOCK, a project on the circadian clock sponsored by the European Commission. Adapted from materials provided by. (Science Daily)
Circling the Square Jun 13, 2008
The FRAXA Research Foundation, a national nonprofit organization, is looking for effective treatment and ultimately a cure. . (Danvers Herald, MA)
Mechanisms Of Common Inherited Mental Retardation Uncovered Jan 9, 2008
The current study was supported by the National Institutes of Health and FRAXA Research Foundation. Adapted from materials provided by. (Science Daily)
Fragile X Syndrome Corrected in Mice Dec 21, 2007
"Needless to say, we are very excited about this publication, which has actually been in the works for a long time," said Dr. Michael Tranfaglia, the medical director of the FRAXA Research Foundation, which is focused on fragile X. "The genetic rescue of most of the major features of fragile X syndrome by decreasing the expression of mGluR5 is an elegant and powerful demonstration of the 'mGluR5' theory.'". In this case, the breakthrough finding has led to the conclusion that fragile X syndrome... (MEDLINEplus)
Gene tinkering curbs autism signsin mice Dec 20, 2007
Drug: FenobamFirm behind it: FRAXA/NeuropharmStatus: Already studied in humans for anxiety; slated to enter trials in Fragile X patients in 2008 ... The Fragile X Research Foundation (FRAXA), which co-funded STX107 research, is supporting investigations involving two other drugs that block the same protein ... We believe that drugs which block mGluR5 have enormous potential for the treatment of fragile X and related developmental disorders, including many cases of autism, said Katie Clapp,... (MSNBC -- Health)
Retardation And Autism Corrected In Mice Dec 20, 2007
This work is supported by the National Institute of Mental Health; the National Institute of Child Health and Human Development; the National Fragile X Foundation; FRAXA, a Fragile X research foundation; and the Simons Foundation. Adapted from materials provided by. (Science Daily)
Brain Defect Helps Drive Fragile X Syndrome Sep 22, 2007
"This is a very exciting paper, which is a powerful confirmation of the mGluR theory of fragile X," said Dr. Michael Tranfaglia, medical director of the FRAXA Research Foundation. "Since FRAXA Research Foundation is currently working with several pharmaceutical companies to bring mGluR5 antagonists into clinical trials for fragile X, we are delighted to see this elegant proof of the therapeutic potential of this class of drugs.". (MEDLINEplus)
How mutant gene causes fragile X Sep 19, 2007
Dr Michael Tranfaglia, medical director of the US FRAXA Research Foundation, said the study was "very exciting". But Dr Mark Hirst, scientific adviser to UK Fragile X Society, said while the study was interesting, the work was still at an early stage. (BBC News -- Science)
FRAXA Research Foundation Works to Provide Hope to Families Struggling to Raise a Child, or Children, with Fragile X Syndrome Jun 29, 2007
Those Of Us At FRAXA Express Our Most Sincere Sympathy Over The Heartbreaking Tragedy Of Chris Benoit, His Wife, And Their Son NEWBURYPORT, Mass. June 28 /PRNewswire/ -- FRAXA Research Foundation is a parent run organization that funds research to find effective treatments and, ultimately, a cure for Fragile X. Fragile X is the leading inherited cause of mental retardation and the most common genetic cause of autism ... FRAXA funds biomedical research, in the US and internationally, aimed at... (PR Newswire)
Researchers Reverse Symptoms In Mice Of Leading Inherited Cause Of Mental Retardation Jun 27, 2007
This work was supported by the FRAXA Foundation, the Simons Foundation, the Wellcome Trust and the National Institutes of Health. Note: This story has been adapted from a news release issued by Massachusetts Institute of Technology. (Science Daily)
Fragile X study raises hopes for autism Jun 26, 2007
There are currently several drugs in development as possible treatments for people with Fragile X Syndrome, said Katie Clapp, co founder of FRAXA Research Foundation, a Newburyport based nonprofit that helped fund the research. Her 18-year-old son has the syndrome, the most common known genetic cause of autism. (Boston Globe)
MIT researchers reverse symptoms in mice of leading inherited cause of mental retardation Jun 26, 2007
This work was supported by the FRAXA Foundation, the Simons Foundation, the Wellcome Trust and the National Institutes of Health. . (EurekAlert!)
Fourth Annual Fragile X Walk scheduled for Saturday in Canton Apr 20, 2007
Organizations receiving the funds are the National FX Foundation; FRAXA (research foundation), and the U.S. Davis MIND Institute, All are non-profit organizations. A silent auction is being held for 51 items which include: a commemorative edition of GOLF Magazine signed by Jack Nicklaus; the handmade bow; comedy basket with 27 comedy CD's, 6 DVD's, 10 tickets to the Jukebox Comedy club, plus more; Paula Deen autographed cookbook; autographed Pablo Ozuna baseball; Bishop Hill Colony basket;... (Canton Daily Ledger, IL)
