Research Sheds Light On Key Trigger Of Embryonic Stem Cell Differentiation Nov 10, 2008
It is the first step toward gastrulation, in which an outer layer of cells dimples inward at what will be either the mouth or anus to form the three distinct precursor cell types shared by most animals: the ectoderm, or outer layer, which forms neurons, skin cells and pigment; the endoderm, or inner layer, which forms many of the organs; and mesoderm, or middle layer, which forms muscle and red blood cells ... Furthermore, the extra Wnt caused the Wnt-responsive cells to differentiate primarily... (Science Daily)
Bizarre medical condition Oct 3, 2008
An ovum after fertilisation starts multiplying and at a certain stage starts differentiating into ectoderm, endoderm and mesoderm, which organises to form a human body ... These cells are toti-potent - they have the potency to become a part of ectoderm, endoderm or mesoderm. (Sify.com, India)
Method To Deliver Molecules Within Embryonic Stem Cells Improves Differentiation Apr 15, 2008
The results revealed enhanced expression of fibroblast growth factor 5 (FGF-5) -- a marker for primitive ectoderm -- in the embryoid bodies mixed with retinoic acid-loaded microspheres compared to the other treatment groups after 10 days. The researchers also confirmed increased or inhibited expression of many additional markers. (Science Daily)
Role Of Tiny RNAs In Controlling Stem Cell Fate Identified Mar 10, 2008
Equally important, they caused other genes that would have told the cell to become ectoderm or endoderm to turn off. For example, expression of a specific factor called Delta-like 1 was repressed by miR-1. (Science Daily)
Catching birth defects early Jan 13, 2008
This embryoid body (EB) consists of different types of cells, representing the three germ layers (the ectoderm, endoderm and mesoderm) ... For example, the skin and the nervous system are formed from the ectoderm, tissues such as cardiomyocytes, bone and blood from the mesoderm and lungs and intestines from the endoderm. (Times of India)
Difference Between Fish And Humans: Century-old Developmental Question Answered Oct 13, 2007
During this stage, the cells group into three layers, the first is the 'ectoderm' which then in turn generates the 'mesoderm' and 'endoderm' layers. In higher vertebrates, such as mammals and birds, the mesoderm and endoderm are generated from an axis running through the centre of the embryo. (Science Daily)
Rare disease doesn't affect boy's spirit Feb 9, 2007
Most people associate the month of February with Valentine's Day and as National Black History Month, but it is also a national awareness month for the medical disorder known as Ectodermal Dysplasia (ED). ED is a disorder which affects the "ectoderm," or outer layer of tissue in a developing baby, which contributes to the formation of the skin, sweat glands, hair, teeth and nails ... Oxford's three year-old Aiden Galdes is affected by a special form of ED called Hypohidrotic Ectodermal Dysplasia... (Oxford Tribune, PA)
Lipid Plays Big Role In Embryonic Development Feb 6, 2007
Medical College of Georgia researchers found that in the first few days of life, ceramide helps stem cells line up to form the primitive ectoderm from which embryonic tissues develop ... They found that in the first few days of life, ceramide helps stem cells line up to form the primitive ectoderm from which embryonic tissues develop, says Dr. Erhard Bieberich, biochemist at the Medical College of Georgia ... In fact, we start out as a wad of cells, but within 24 hours, some cells die and others... (Science Daily)
New Source of Stem Cells: Amniotic Fluid Jan 8, 2007
This range comprises all three embryonic germ layers: the mesoderm, the progenitor of bone, muscle and connective tissue; the endoderm, which develops into digestive organs as well as the lungs; and ectoderm, which becomes nerves, skin and the brain. In addition to laboratory experiments, the team studied AFS cells in mouse models, grafting neural stem cells into the brains of mutant mice with disrupted neural development and growing bone tissue in another set of immunodeficient mice. (Scientific American)
Scientists discover new, readily available source of stem cells Jan 8, 2007
The scientists noted that specialized cells generated from the AFS cells included all three classes of cells found in the developing embryo - termed ectoderm, mesoderm, and endoderm. In their high degree of flexibility and growth potential, the AFS cells resemble human embryonic stem cells, which are believed capable of generating every type of adult cell. (EurekAlert!)
