A better genetic test for autism Mar 15, 2010
Chromosomal microarray analysis (CMA) is a genome-wide assay that examines the chromosomes for tiny, sub-microscopic deletions or duplications of DNA sequences, known as copy-number variants ... In addition, by pinpointing bits of chromosomes that are deleted or duplicated, CMA can help researchers zero in on specific causative genes within that stretch of DNA. They can also begin to classify patients according to the type of deletion or duplication they have, and try to find specific treatment... (EurekAlert!)
Democrats Seek Agreement, Vote On Health Care Mar 14, 2010
The president wants creation of a commission with authority to force savings in Medicare, for example, and is seeking the deletion of items sought by individual senators. Those were among the issues still in dispute after days of secretive talks involving the White House and House and Senate leaders. (KIRO TV, WA)
Kenya: Proposed Constitutional Amendment Sets Back Women's Rights Mar 12, 2010
"The PSC did the unthinkable and recommended the deletion of the state's obligation to domesticate international human rights instruments. They also deleted the provision on social and economic rights and relegated to parliament the sole power to decide through legislation when and how the rights and standards can be applicable in national context," Kimani explained. Pricilla Nyokabi, executive director of women's rights group Kituo cha Sheria, agreed that parliament should be left no option but... (allAfrica.com)
Researchers undertake search for vaccine for cancer Mar 4, 2010
"We re using peptides [the bases of protein] to stimulate a specific response, said Slansky, the part of the response that won t be directed to non-cancer cells. [The response] is toward cancer, is the idea there. We re using an insect-cell-based vaccine, Slansky said. It s a system that expresses proteins at a really high level, and since its foreign, we can get a really good non-specific response. The problem with the cancer cells is that they re similar enough to avoid detection by the immune... (UCD Advocate, CO)
No Implants Needed: Movement-Generating Brain Waves Detected and Decoded Outside the Head Mar 3, 2010
"We know the brain is highly redundant, so we think that even if there's a deletion in the brain, we might be able to decode from another place. One advantage to using electroencephalography is access to the whole brain, not just a specific area.". . (Scientific American)
Haiti benefit reaches $50k goal Mar 2, 2010
Tuesday, March 2, 2010. Published: Monday, March 1, 2010. (Boston University Daily Free Press, MA)
Online UpdateSyracuse University cancels Thursday afternoon, evening classesClasses canceled due to snow for third time since 1993Posted: 2/25/2010, 12:54 PMClasses after 2 p.m. Thursday were cancelled at around 11:30 a.m. due to severe weather conditions, according to an e-mail from Syracuse University News Services. This is the third time classes have been cancelled due to snow since 1993.The decision to cancel classes was made by the university's emergency preparedness committee, which includes Erica Spina, vice chancellor and provost, Louis Marcoccia, chief financial officer, said Sara Miller, associate director of news services. Feb 26, 2010
Syracuse University cancels Thursday afternoon, evening classes - News. Media Credit: Will Halsey. (Daily Orange, NY)
Syracuse University cancels Thursday afternoon, evening classes Feb 26, 2010
Media Credit: Will Halsey. Classes after 2 p.m. Thursday were canceled at around 11:30 a.m. due to severe weather conditions, according to an e-mail from Syracuse University News Services. (Daily Orange, NY)
Gene Mutation Is Linked to Autism-Like Symptoms in Mice, Researchers Find Feb 25, 2010
24, 2010) When a gene implicated in human autism is disabled in mice, the rodents show learning problems and obsessive, repetitive behaviors, researchers at UT Southwestern Medical Center have found. The researchers also report that a drug affecting a specific type of nerve function reduced the obsessive behavior in the animals, suggesting a potential way to treat repetitive behaviors in humans. (Science Daily)
Centerra Gold Reports 2009 Results; Fourth Quarter Earnings of $0.60 per Share Feb 24, 2010
Reconciliation of Gold Reserves and Resources (in thousands of ounces of contained gold)(8)(9) ---------------------------------------------------------------------------- December Jan-1 to Nov-1 to 2009 December Centerra 31 2008(1) Oct-31 2009 Dec-31 2009 Addition 31 2009 Share(4) Through- Through- (Deletion) put(2) put(2) (3) ---------------------------------------------------------------------------- Reserves - Proven and Probable... (CCNMatthews Press Releases)
From Uncharted Region of Human Genome, Clues Emerge About Origins of Coronary Artery Disease Feb 23, 2010
Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice. Nature, 2010; DOI. (Science Daily)
Critical Enzyme in Healthy Heart Function Identified Feb 21, 2010
Heart-specific Deletion of CnB1 Reveals Multiple Mechanisms Whereby Calcineurin Regulates Cardiac Growth and Function. Journal of Biological Chemistry, 2010; 285: 6716-6724 DOI. (Science Daily)
Genomic Map Spanning Over Two Dozen Cancers Charted Feb 19, 2010
Instead of the usual two copies, tumors often carry several copies of one piece of DNA (an "amplification") or may lack it altogether (a "deletion") ... In an analysis of 17 different cancer types, the researchers found that a majority of amplifications and deletions are present in more than one type. (Science Daily)
ETSU students honored with 'Who's Who' recognition Feb 11, 2010
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Free HIV/AIDS testing available Friday Feb 10, 2010
The third annual Love Yourself HIV Testing Event will be take place Friday from 9 a.m. to 5 p.m. at the LGBT Resource Center at 750 Ostrom Ave.. Love Yourself allows people to get an HIV test for free in a safe and private environment, said Lauren Hannahs, a graduate assistant at the LGBT Resource Center. (Daily Orange, NY)
JCI online early table of contents: Feb. 8, 2010 Feb 9, 2010
As deletion of Usag1 in Col4a3/ mice led to substantial attenuation of disease progression, preservation of kidney function, and extension of life span, the authors suggest that inhibiting USAG-1 might be a promising therapeutic approach for the treatment of Alport syndrome. TITLE: Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome. (EurekAlert!)
'Buy America' clause waived for Canada Feb 6, 2010
Canada, the European Union and Australia called the 'Buy America' clause a protectionist measure and sought its deletion. However, Canadian International Trade Minister Peter Van Loan announced Friday that the Americans have granted exemption to Canadian companies to bid for public works projects in 37 states of the US. Canada does more than 80 percent of its international trade with the US.. (India Times, India)
Some Obese People May Lack Genes Feb 5, 2010
7 percent, or seven in every thousand, of morbidly obese people have a "micro-deletion" of genetic code, located on chromosome 16 ... Those with the deletion tended to be of normal weight as toddlers, became overweight in childhood, and then became severely obese in adulthood ... Eleven people inherited the deletion from their mother and four from their father, while 10 deletions apparently occurred by chance, they found. (Newsmax)
Credibility Deleted Along With E-Mails Feb 5, 2010
They're the ones who filed a lawsuit last spring, accusing the then-governor of "the systematic deletion, destruction or concealment" of electronic communications that are supposed to be available to the public. Reprehensible Secrecy. (The Pilot Newspaper)
Some Morbidly Obese People Are Missing Genes, Shows New Research Feb 4, 2010
The researchers believe there may be other genetic deletions, in addition to those just identified, that increase a person's risk of becoming obese ... They found 31 people who had nearly identical 'deletions' in one copy of their DNA. All of the adults with this genetic change had a BMI of over 30, which means they were obese ... They identified 19 more people with the same genetic deletion, all of whom were severely obese, but did not find the deletion in any healthy normal weight people. (Science Daily)
Gene loss link to severely obese Feb 4, 2010
The gene "deletion" could not be found in people of normal weight ... They researchers found 31 people who had nearly identical "deletions" in their genetic code, all of whom had a BMI of over 30, meaning they were obese ... The precise function of the missing genes is unclear, as is the precise nature of the relationship between learning difficulties and obesity - none of the people with the deletions in the wider study had learning problems. (BBC News -- Health)
Very Obese People May Be Missing Genes Feb 4, 2010
Nineteen people had the same genetic deletion, and all were severely obese. "We feel that this is a major advance -- the first paper to convincingly demonstrate that a relatively rare genetic variant can also be an important cause of common obesity," said study co-author Alexandra Blakemore, a senior lecturer at Imperial College London. (Atlanta Journal-Constitution -- Health)
Books Pulled From Amazon.com In Pricing Dispute Jan 31, 2010
It was a deletion of pirated copies that had been posted to the Kindle store, but the ordeal highlighted a concern -- that a book already paid for and acquired can be revoked by an e-tailer. The Kindle operates on a wireless connection that Amazon ultimately controls. (KSBW 8, CA)
Hypervariable intronic region in NCX1 is enriched in short insertion-deletion polymorphisms and showed association with cardiovascular traits Jan 28, 2010
45%) was actually a human-specific deletion compared to other primates. In humans, this deletion was surrounded by other short (5-43bp) deletion variants and a duplication (40bp) polymorphism possessing overlapping breakpoints ... This indicates a potential indel hotspot, triggered by the initial deletion in human lineage. (BioMed Central)
The pop heard 'round College Station Jan 26, 2010
Derrick Roland's season-ending injury has already taught him a lot. Issue date: 1/26/10 Section. (The Battalion, TX)
Williams–Beuren Syndrome Jan 21, 2010
Estimated to occur in approximately 1 in 10,000 persons,1 Williams Beuren syndrome is a microdeletion disorder, or contiguous-gene-deletion disorder, that can serve as a model for the study of genotype phenotype correlations and potentially reveal. . (New England Journal of Medicine)
Barnhart sets agenda as term begins Jan 20, 2010
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Loss of Epigenetic Regulators Causes Mental Retardation Jan 19, 2010
First author Anne Schaefer, a senior research associate in Greengard's lab, subjected these mice to a battery of behavioral tests and determined that they behave much like humans with a mental retardation syndrome called the 9q34 deletion syndrome, in which the region of chromosome 9 that codes for the GLP genes is missing. The mice lacking GLP/G9a, unlike their normal counterparts, were not afraid of open space, were lethargic (and as a result, obese) and had problems learning to adapt to their... (Science Daily)
Largest academic-industry collaboration for drug discovery in depression and schizophrenia launched Jan 19, 2010
It will examine how new genetic findings (duplication and deletion or changes in genes) influence the response to various drugs and whether this information can be used to choose the right drug for the right patient. And finally, it will try and develop new approaches for shorter and more efficient trials of new medication trials that may require fewer patients and give faster results. (EurekAlert! -- Business News)
Chimp and Human Y Chromosomes Evolve Fast Jan 14, 2010
Disadvantages from a less-than-ideal gene version or even the deletion of a section of the chromosome may have been outweighed by the advantage of improved sperm production, resulting in a Y chromosome with far fewer genes than its human counterpart. To determine whether this rapid rate of evolution affects Y chromosomes beyond those of chimps and humans, the Page lab and the Washington University Genome Center are now sequencing and examining the Y chromosomes of several other mammals. (Science Daily)
McGwire admits to steriod use Jan 12, 2010
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Frozen job market restricts graduates Jan 12, 2010
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Research adds to evidence that autism is a brain 'connectivity' disorder Jan 10, 2010
Sahin has also been studying additional genes previously found to be deleted or duplicated in patients with autism, and finding that deletion of some of them causes neurons to produce multiple axons an abnormality that, again, appears to be reversed with rapamycin. "Many of the genes implicated in autism may possibly converge on a few common pathways controlling the wiring of nerve cells," says Sahin. (EurekAlert!)
Post a resume Jan 10, 2010
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