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    News and Articles on BRMs Modifiers



    Obese Kids Who Snore More Sleepy in the Daytime  Dec 31, 2008
    This suggests, the researchers say, that sleep fragmentation my be more common in obese children and that a lack of oxygen during sleep may play a significant role in triggering the biological response that ultimately leads to increased daytime sleepiness. While obstructive sleep apnea was more common among the obese children than the slimmer children, obese children without the condition were still more likely to have excessive daytime sleepiness than their slimmer counterparts. (MEDLINEplus)

    Cutting back on fats, fruit for a more effective diet  Dec 10, 2008
    From what you have told me, your appetite seems to come as a biological response to your active lifestyle, which means it is more likely physiological than psychological (love of food). I will provide some tips to make your dieting effort easier, hopefully giving you the best results in terms of bringing your body fat level down yet still nourishing your body adequately. (Jakarta Post, Indonesia -- Features)

    Physically Active Prepubescent Boys Sleep Less  Dec 6, 2008
    They also suggest further studies to determine if associations between regulated and spontaneous physical activity and if the need to rest is an age-associated biological response or if it is a result of other external factors. Nonetheless, these findings provide additional evidence of a child-specific control of physical activity that may converge to a more adult-type pattern after puberty. (MEDLINEplus)

    Lorus Therapeutics Announces Receipt of Milestone Payment and Extension of Exclusive License Agreement for Virulizin(R)  Oct 15, 2008
    Virulizin is a novel biological response modifier (or immunotherapeutic agent) that stimulates the immune system through several mechanisms, including the activation of macrophages and the infiltration of natural killer cells into tumors. Virulizin has demonstrated significant anticancer activity against a wide range of human cancers in preclinical studies, and has been tested in several clinical trials in solid tumor indications, including a Phase III clinical trial in combination with... (CCNMatthews Press Releases)

    Women Respond Better Than Men to Antidepressant  Sep 13, 2008
    "The elimination of these potential explanations for the sex differences found in this study increases the likelihood that the explanation is a differential biological response to citalopram in women.". The researchers suggest that the better treatment response among women is related to "the role of estrogen on serotonergic systems," as well as cognitive and psychological factors that differ between men and women. (MEDLINEplus)

    LETTERS: NCT, Aug. 28, 2008  Aug 29, 2008
    We need to know the biological response of agricultural and natural ecosystems to the changed climate. Only then can we gauge the impacts of our actions, and help to adapt precisely to the changes. (North County Times)

    Sex And Lifespan Linked In Worms  Jul 25, 2008
    "One interesting aspect is that a whole family of compounds is necessary to elicit a biological response. One by itself doesn't do much, but two or three together give a strong response," says Schroeder. Surprisingly, the same group of compounds can also trigger young worms to enter the long-lived dauer stage. (Science Daily)

    Culture and depression  Jul 15, 2008
    As Dr. Bagby explains, "the onset of depression triggers a biological response that takes place within a specific social context, resulting in a cascade of somatic and psychological experiences that are interpreted through a particular cultural lens. Careful translation and adaptation of our assessment tools helped us clarify if different approaches lead to different symptom profiles and conclusions about patients.". Overall, the data demonstrate a consistently greater level of psychological... (EurekAlert!)

    Lorus Therapeutics Announces Exclusive Multinational License Agreement with Zoticon Bioventures for Virulizin(R)  Apr 9, 2008
    Dial in numbers are below: Toronto: 1-416-644-3422 Toll-free: 1-800-732-0232 About Virulizin(R) ------------------ Virulizin(R) is a novel biological response modifier (or immunotherapeutic agent) that stimulates a patient's immune system through several mechanisms, including the activation of macrophages and the infiltration of natural killer cells into tumors. Virulizin(R) has demonstrated high levels of antitumor activity against a number of cancer indications including pancreatic cancer. (PR Newswire)

    Two-photon Nanoparticles For The Improved Detection Of Tumor Cells  Apr 2, 2008
    The latter forms the ligand (molecule binding to the active site of a protein: This binding generally triggers a biological response) recognized by the receptors of HeLa cells (cervical cancer) and MCF7 cells (breast cancer). These results should enable the 3D targeting and imaging of the tumor. (Science Daily)

    Tailored Clopidogrel Dosing Improves PCI Outcomes  Mar 30, 2008
    "This is the first study demonstrating that adjusting the clopidogrel loading dose according to the patient's individual biological response can improve prognosis after percutaneous coronary revascularization," Dr. Bonello said. Dr. Bonello will present the results of this study on Saturday, March 29 at 8:45 a.m. CDT in the Grand Ballroom, S100. (PR Newswire)

    Letters to the Editor - 2/25/2008  Feb 26, 2008
    Bank Enterprise Award Program; Barry M. Goldwater Scholarship Program; Basic and Applied Scientific Research; Basic Center Grant; Basic, Applied, and Advanced Research in Science and Engineering; Basic/Core Area Health Education Centers; Beach Erosion Control Projects; Beach Monitoring and Notification Program Implementation Grants; Benjamin Gilman International Scholarship; Bilingual/Bicultural Service Demonstration Grants; Bill Emerson Humanitarian Trust; Biobased Transportation Research;... (North County Times)

    Predicting Radiation Risk To Astronauts On Columbus, International Space Station  Feb 19, 2008
    "The main uncertainties in these calculations are our knowledge of the space radiation environment beyond the Earth s magnetic field, and the biological response to radiation," says Ersmark. To provide the environmental information ESA is flying a standard radiation monitor on a number of its spacecraft, including Proba-1, Integral, Rosetta, GIOVE-B, Herschel and Planck. (Science Daily)

    * New research says MMR vaccine does not cause autism  Feb 7, 2008
    The study, which appears in the Archives of Disease in Childhood published by the British Medical Association (BMA), found no evidence of any abnormal biological response from the shot that could point to a link between the vaccine and autism. The investigation by British doctors comes nearly 10 years to the day since a paper, appearing in The Lancet, unleashed a health scare that prompted many parents to refuse the MMR jab for their children. (Taipei Times, Taiwan -- World)

    Study: MMR Vaccine Doesn't Cause Autism  Feb 5, 2008
    The study, published on Tuesday in the Archives of Disease in Childhood, found no evidence of any abnormal biological response from the shot that could point to a link between the vaccine and autism. "This study really supports the view these are safe vaccines," said David Brown, a researcher at Britain's Health Protection Agency who worked on the study. (Newsmax)

    CeloNova BioSciences Introduces a New Class of Coronary Stent: The CATANIA(TM) Coronary Stent System with NanoThin Polyzene(R)-F  Jan 20, 2008
    -- Protection from stent thrombosis -- The Polyzene(R)-F surface treatment is bacterial-resistant "The FDA has cautioned physicians about a small but significant increased risk of stent thrombosis for patients with drug-eluting stents. Now, Britain's National Institute for Health and Clinical Excellence is considering restrictions on DES because they are not cost-effective for most patients and because of uncertainties about safety. Polyzene(R)-F seems to solicit a positive biological response... (PR Newswire)

    The Meaning of Color in Fashion  Jan 16, 2008
    Red also produces a biological response, getting people all hot and bothered by quickening the pulse and increasing the breathing rate. While red is definitely regarded as a sexy color that draws attention, red also makes the wearer look heavier and is an appetite stimulant perhaps this explains common weight gain during the holiday season. (Suite101.com)

    Prescription For Addiction  Dec 10, 2007
    "This tool is different. This tool has a unique and powerful biological response that is very robust," says Dr. Matthew Torrington, the medical director of the Prometa Center of Los Angeles. Dr. Torrington has done addiction research at UCLA. He started prescribing Prometa two years ago. (CBS News)

    A French tradition: Why work when you can hibernate?  Nov 26, 2007
    " It is unlikely this was hibernation in the zoological sense. While extreme cold might have set off a biological response normally seen only in squirrels, bears and marmots, human hibernation probably reflects a sensible, communal decision to stay in bed for as long as possible. But the French seem to have been particularly sleepy. They "hibernated" even in temperate zones. In Burgundy, after the wine harvest, the workers burned the vine stocks, repaired their tools and left the land to the... (International Herald Tribune)

    Biomarkers Predict Risk For Invasive Breast Cancer Years Before The Tumor Develops  Nov 14, 2007
    13, 2007) A specific biological response to cellular stress may predict the likelihood of future tumor formation of the most common, non-invasive form of pre-malignant breast cancer-- ductal carcinoma in situ, or DCIS. ... The research results are also significant because traditional tests available today are not strong enough to predict whether or not a woman will develop a future cancer after diagnosis with DCIS. By identifying this particular biological response in patients, physicians may... (Science Daily)

    The REAL Reasons Diets Don't Work  Oct 21, 2007
    This biological response is the same whether or not the stress is life threatening. In fact, the body responds with over 2500 reactions, which affect every system including metabolism, blood sugar, hormonal function, and appetite (among many, many other things). (Suite101.com)

    Renowned specialist joining NM Cancer Center  Oct 8, 2007
    Prior to founding Cancer Therapeutics, he initiated the National Cancer Institute's Biological Response Modifiers Program and established 's Oncology Division. He holds or has held membership in 19 professional societies. (New Mexico Business Weekly, NM)

    Program Alters Kids' Biological Response to Stress  Oct 4, 2007
    Tuesday, October 2, 2007. NEW YORK (Reuters Health) - Researchers for the first time have evidence that a family intervention known to improve behavior of preschoolers' at risk for antisocial behavior also favorably alters how their bodies react to stressful social situations. (MEDLINEplus)

    Early Family Intervention Alters Preschoolers' Biological Response To Stress  Oct 3, 2007
    Now a new study shows that a non-medical early family intervention that improves caregiving also results in important changes in children's biological response to stress ... Dr. Brotman and her colleagues evaluated whether a program designed to prevent antisocial behavior in high risk preschoolers could alter the children's biological response to a stressful social situation. (Science Daily)

    New answers for addiction through science  Aug 27, 2007
    From the outset, their biological response was the opposite from the majority of the population. Likewise, their withdrawal experience was much more severe and long-lived. (North County Times)

    NHS failings over IVF treatment  Aug 12, 2007
    "This is a biological process and the more we can respond to the biological response the better. "You are more likely to improve your pregnancy rates if you can adapt to the needs of the particular patient. " Big variations According to figures from the regulator, the Human Fertilisation and Embryology Authority, IVF clinic success rates range from around 50% for the best performing clinics to 10% for the worst. Clare Brown, from the patient group Infertility Network UK, said the impact... (BBC News -- UK)

    Thwarting Terror: Genes Can Tell the Story of Radiation Exposure  Apr 6, 2007
    "There's a complex molecular biological response to radiation that seems very unique at different dose levels," Chute says. "The classes of genes that respond are unpredictable and not [generally] overlapping.". (Scientific American)

    Green chemistry can help nanotechnology mature, Oregon professor says  Feb 19, 2007
    Hutchison, who is director of the UOs Material Sciences Institute, is developing diverse libraries of nanoparticles, in which we systematically bury the structural parameters and use in vivo and in vitro assays to determine the relationship between biological response and structural parameters. . (EurekAlert!)

    Scientists Identify Gene That May Indicate Predisposition To Schizophrenia  Jan 26, 2007
    Specifically, their findings identify the chitinase 3-like 1 gene as a potential schizophrenia-susceptibility gene and suggest that the genes involved in biological response to adverse conditions are likely linked to schizophrenia ... support the proposal that genes involved in biological response to adverse environmental conditions play roles in the predisposition to schizophrenia. (Science Daily)

    Restarting Tumor-Suppressor Gene May Fight Cancer  Jan 25, 2007
    Lowe said he also believes that "there are other members of the p53 pathway that can either turn the pathway on or execute the [relevant] biological response. All of them could have a similar biology, and we could imagine tinkering with them to do similar things.". But researchers have their work cut out for them, he said. (Forbes)



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