Blood Sugar Linked To Normal Cognitive Aging Jan 1, 2009
8, 2008) Diabetes and high levels of blood sugar may be linked to abnormalities in a person's body clock and sleep patterns, according to a genome-wide association study published in the journal Nature. . (Science Daily)
A Syndrome with Congenital Neutropenia and Mutations in G6PC3 Jan 1, 2009
Results All index patients were susceptible to bacterial infections and had very few mature neutrophils in the bone marrow; structural heart defects, urogenital abnormalities, and venous angiectasia on the trunk and extremities were additional features. Linkage analysis of the two index families yielded a combined multipoint lod score of 5. (New England Journal of Medicine)
Girl Thrives After Doctors Remove Third of Heart Dec 31, 2008
Kirsty had been born with an abnormality in her blood vessels, which starved her heart muscle of oxygen. By the time she was a few months old, she had suffered countless heart attacks, leaving her heart twice as big as it should have been. (Fox News)
Class Status Denied in Suit Against DuPont Over Chemical-Tainted Water Dec 31, 2008
Bumb said in her opinion that the health effects "appear to be uncertain" but that some studies have shown that exposure to the chemical may cause liver disease, cancers and cholesterol abnormalities. The N.J. Department of Environmental Protection has issued preliminary guidelines requiring that water supplies have PFOA levels lower than. (Law.com)
* YEAR in Review~^U: Pop Stop Dec 31, 2008
Some newspapers speculated that the 39-year-old Wongs advanced age might have contributed to the miscarriage or that it might actually have been an induced abortion after Wongs doctor discovered that the fetus had some sort of abnormality. . (Taipei Times, Taiwan -- World Business)
PHANTOM PAINS: Fibromyalgia sufferers find relief in diagnosis, approved and unproven treatments Dec 30, 2008
Disclaimer - If ad is a click thru and you are having problems please click on link to download latest version of flash player. You are not logged in. (Orangeburg Times and Democrat, SC)
TV show on Maine 'Mermaid Girl' airs Sunday Dec 30, 2008
The condition is also accompanied by an array of other abnormalities, including kidney, colon and genital deformities. Scientists say sirenomelia occurs in between 1 in 70,000-100,000 pregnancies, the majority of which do not continue full-term. (Seacoast New Hampshire)
Hebrew University scientists succeed through stem cell therapy in reversing brain birth defects Dec 30, 2008
Neural and behavioral birth defects, such as learning disabilities, are particularly difficult to treat, compared to defects with known cause factors such as Parkinson's or Alzheimer's disease, because the prenatal teratogen the substances that cause the abnormalities -- act diffusely in the fetal brain, resulting in multiple defects. Prof. (EurekAlert!)
Inhibition of the Bcl-xL Deamidation Pathway in Myeloproliferative Disorders Dec 27, 2008
Methods We searched for abnormalities of the proapoptotic Bcl-xL deamidation pathway in primary cells from patients with chronic myeloid leukemia (CML) or polycythemia vera, myeloproliferative disorders associated with the BCR-ABL fusion kinase and the Janus tyrosine kinase 2 (JAK2) V617F mutation, respectively. Results The Bcl-xL deamidation pathway was inhibited in myeloid cells, but not T cells, in patients with CML or polycythemia vera. (New England Journal of Medicine)
Primary Cilium As Cellular 'GPS System' Crucial To Wound Repair Dec 26, 2008
Once written off as a vestigial organelle discarded in the evolutionary dust, primary cilia in the last decade have risen to prominence as a vital cellular sensor at the root of a wide range of health disorders, from polycystic kidney disease to cancer to left-right anatomical abnormalities. The paper, Poster B262, titled, "The primary cilium coordinates directional cell migration," will be presented on Wednesday, Dec. 17, 2008, in session 2553, Cilia and Flagella IV, in Halls A-C, Moscone... (Science Daily)
Man committed to Iowa's sexually violent predator unit Dec 26, 2008
Ultimately, Cleve determined that the state proved the three items necessary for a civil commitment: that DeMoss had been convicted of, or charged with, a sexually violent crime, that he suffers from a mental abnormality and that the abnormality makes him likely to offend again if he is not confined. DeMoss has appealed the decision. (Waterloo-Cedar Falls Courier)
Treating the Side Effects of ART Dec 25, 2008
While side effects vary with each medication, the most common side effects include diarrhea, nausea, vomiting, rashes, weight loss, and lipid abnormalities ... Lipid abnormalities, including high cholesterol, are more common in patients taking antiretroviral drugs than in those not taking them. (Suite101.com)
FDA Approves Ferring Pharmaceuticals' Degarelix (Generic Name) for Treatment of Advanced Prostate Cancer Dec 25, 2008
Physicians should consider whether the benefits of androgen deprivation therapy outweigh the potential risks in patients with congenital long QT syndrome, electrolyte abnormalities, or congestive heart failure and in patients taking Class IA (e. g. quinidine, procainamide) or Class III (e. (PR Newswire)
Memory Pharmaceuticals Initiates Biomarker Study of R3487/MEM 3454 in Schizophrenia Dec 25, 2008
Studies have shown that this abnormality is genetically linked to the nicotinic alpha-7 receptor and can be measured through the P50 auditory evoked response, a waveform measured 50 milliseconds after an auditory stimulus. Recent scientific studies have shown that a nicotinic alpha-7 agonist can improve both cognition and P50 inhibition, giving rise to the possibility that P50 can be used to track cognitive effects for this class of compounds. (PR Newswire)
Lupus Affects the Brain Very Early in the Disease Dec 25, 2008
Among a group of 97 patients with newly diagnosed SLE, 25 percent had brain abnormalities on magnetic resonance imaging (MRI), researchers found ... Given the high frequency of neurological and psychiatric SLE manifestations and structural brain abnormalities, more research is urgently needed to determine the underlying cause of these changes, "in order to develop rational treatment options," the team concludes. (MEDLINEplus)
Abnormal ECG Seen in Psoriatic Arthritis Patients Dec 25, 2008
Based on their observations, Zisman and colleagues conclude that a large study with a long followup period is warranted to further investigate these conduction abnormalities and to see if they are related to cardiovascular disease. SOURCE: Journal of Rheumatology, December 2008. (MEDLINEplus)
Israeli scientists reverse brain birth defects using stem cells Dec 25, 2008
Unlike neural disorders such as Parkinson's or Alzheimer's, the prenatal teratogen - the substances that cause the abnormalities - act diffusely in the fetal brain, resulting in multiple defects. A team of researchers from the Hebrew University of Jerusalem-Hadassah Medical led by Prof. (Israel 21C)
Slamming Brakes On Deadly Ovarian Cancer Cells: Blocking Proteins Coded By Notorious Cancer-causing Gene Dec 25, 2008
(July 11, 2000) A Johns Hopkins research team has discovered a new family of genes that contributes to the process of malignancy, shedding new light on the abnormalities that give rise to the aggressive childhood. (Feb. (Science Daily)
Sleep disorder may be early sign of dementia or Parkinson's disease Dec 25, 2008
The disorder can also be caused by narcolepsy or rare brainstem abnormalities. REM sleep disorder from these causes does not necessarily carry the risk of developing a neurodegenerative disease, he said. (EurekAlert!)
Health briefs Dec 23, 2008
Common reasons for evaluation or counseling can include a variety of conditions, including: birth defects, behavioral abnormalities, familial hearing loss or blindness, abnormal growth patterns, chromosomal abnormalities, congenital, or prenatal exposure to drugs, alcohol, or medications. Shodair staff also provides risk assessments and counseling for families who may have a risk of inherited cancers. (Helena Independent Record, MT)
Polycarb water bottles harmful to health Dec 23, 2008
GEORGE TOWN: Polycarbonate water bottles are harmful and the use of them may be linked to many health abnormalities, says the Consumer Association of Penang. Its president S.M. Mohamed Idris said that polycarbonate-made water bottles will leach out bisphenol A (BPA), a potent hormone disruptor which can have a detrimental effect on future generations. (The Star Online, Malaysia)
The Dumbing Down of Academe Dec 23, 2008
Patient has two teenage children, but no other abnormalities. Next time that I need surgery, I will consult a "Do It Yourself" manual. (Townhall.com)
Baby Girl Free Of Breast Cancer Gene Due To Be Born Soon Dec 23, 2008
Some couples may have experiencds several miscarriages due to chromosomal abnormalities. Source. (Medical News Today)
Drinking During Pregnancy Could Damage Offspring's White Matter Dec 23, 2008
" Previous research has found that white matter is a specific target of alcohol teratogenesis, and that the corpus callosum, caudate nucleus, and cerebellum appear to be disproportionately vulnerable to the effects of prenatal alcohol exposure. The researchers used diffusion tensor imaging (DTI) to assess the microstructure of white matter in the brains of 27 patients ages eight to 18. DTI like other MRI techniques can depict biological tissues at the microstructural level, providing an improved... (MedPage Today)
Video: Gleevec Receives US Approval as First Treatment To Reduce Risk of Cancer Returning in Patients with Gastrointestinal Stromal Tumors Dec 20, 2008
In previous Phase III unresectable and/or metastatic GIST trials (400 mg/day; 800 mg/day) severe (NCI Grades 3/4/5) lab abnormalities -- including neutropenia (3%; 4%), and anemia (5%; 6%) -- and severe adverse reactions (NCI Grades 3/4/5), including edema (9%; 13%), fatigue (12%; 12%), abdominal pain (14%; 12%), nausea (9%; 8%), diarrhea (8%; 9%), rash (8%; 9%), vomiting (9%; 8%) and myalgia (6%; 4%) were reported among patients receiving Gleevec ... In CML clinical studies, severe (NCI Grades... (PR Newswire)
Study Of Placenta Unexpectedly Leads To Cancer Gene Dec 20, 2008
But when the p53 molecule is aberrantly regulated, either by an outside virus or an inherited genetic abnormality, the risk of cancer is higher because p53 cannot perform its job. Researchers also found that SENP2 indirectly regulates p53 activity through another protein called Mdm2, which was already known to be involved in some cancers. (Science Daily)
Higher Levels Of Obesity-related Hormone Found In Patients With Psoriasis Dec 20, 2008
19, 2008) Patients with the skin disease psoriasis appear more likely to have higher levels of leptin (a hormone produced by fat cells that may contribute to obesity and other metabolic abnormalities) than persons without psoriasis, according to a new report. See also. (Science Daily)
Baby Is Cancer Miracle Dec 20, 2008
Fertility expert Paul Serhal said: "This is a landmark technique and can now be offered as a successful option to other couples who carry this genetic abnormality.". The technique can also be used to screen for other genetically inherited conditions such as cystic fibrosis and muscular dystrophy. (Glasgow Daily Record)
Video: Siemens Healthcare and Hospital Clinic, Barcelona Enter Agreement to Use Integrated Laboratory Diagnostics, Imaging and Information Technology Systems to Advance Patient Care Dec 19, 2008
Siemens will work with the hospital's experts in three specific areas -- liver fibrosis, fetal medicine and colon cancer -- to develop specific practices to increase early detection of diseases or abnormalities. These practices will be based on integrating patient data from the laboratory, imaging and information technology systems. (PR Newswire)
Babysitter Suzanne Holdsworth cleared of murdering toddler Kyle Fisher Dec 19, 2008
Kyle suffered from a number of pre-existing brain abnormalities, some of which even on their own would have left him pre-disposed to epilepsy, she said. Prof Squier added: "I have never seen a brain where all of these features have come together. "It is quite unique. (Telegraph.co.uk)
Health providers' 'conscience' rule to take effect Dec 19, 2008
For example, they said, an antiabortion doctor in a federally funded clinic might refuse to tell a pregnant patient that her fetus had a severe abnormality. Or an emergency room worker might withhold from rape victims information about emergency contraception. (Los Angeles Times)
Autism And Schizophrenia Share Common Origin, Review Suggests Dec 19, 2008
The developmental psychologist demonstrated that both mental diseases have similar physical abnormalities which are formed during the first month of pregnancy ... Interestingly, many physical abnormalities of autistics are also prevalent in schizophrenics ... As people with schizophrenia and autism frequently have physical abnormalities to body parts formed during early organogenesis, Ploeger concluded that the foundation for these psychiatric disorders is laid very early during pregnancy. (Science Daily)
Jawai a step closer to NBA debut Dec 18, 2008
The Toronto Raptors' Australian NBA rookie forward Nathan Jawai, sidelined since training camp because of an unidentified heart abnormality, has been cleared to begin workouts. "It's going to be a little bit of time before he's in any kind of shape to play but at least we can start working with him and hopefully get him ready to help out some time in the New Year," coach Jay Triano said on Wednesday. (Sydney Morning Herald -- Sport)
Colorado Doctor Finds Foot In Newborn's Brain Dec 18, 2008
It could also be a case of fetus in fetu, which is a developmental abnormality in which a fetal twin begins to form within the other. Grabb told the paper he sees a teratoma once every few years but it doesn't compare to Sam's. (Click2Houston, TX)
Implantable Monitor May Help In Managing Diastolic Heart Failure Dec 18, 2008
8, 2003) More than one-fourth of adults over age 45 have abnormalities in the way their heart fills with blood and are at significantly increased risk for premature death, according to results of a study of. . (Science Daily)
When It's More Than The 'Terrible Twos' Dec 18, 2008
Among the many potential causes of regression, Stefanatos said health care providers or autism specialists who suspect RASD should look for evidence of an electroencephalographic (EEG) abnormality, which might suggest an epileptic or seizure disorder. An EEG measures electrical activity produced by the brain and is recorded from electrodes placed on the scalp. (Science Daily)
NBA Insider: Right or left, Blazers' Roy on a hot streak Dec 18, 2008
Toronto Raptors rookie forward , sidelined since training camp because of an unidentified heart abnormality, has been cleared to begin workouts. He was cleared after a medical visit Tuesday and is expected to need a month of workouts before he's ready to play. (USA Today -- Sports)
DIY HPV testing gets cool response Dec 18, 2008
Inserting a tampon obviously, also does not rule out the possibility of other abnormalities which could be detected at the time of a Pap smear. . (6minutes)
Experienced Pilots May Be At Risk Of DNA Damage From Ionizing Radiation Dec 17, 2008
The research team compared the rate of chromosomal (DNA) abnormalities in blood samples taken from 83 airline pilots and 50 university faculty members from the same US city ... Chromosomal abnormalities have been associated with an increased risk of cancer. (Science Daily)
Cellular Stress Causes Fatty Liver Disease In Mice Dec 17, 2008
16, 2008) A University of Iowa researcher and colleagues at the University of Michigan have discovered a direct link between disruption of a critical cellular housekeeping process and fatty liver disease, a condition that causes fat to accumulate in the liver. The findings, published in the Dec. 9 issue of the journal Developmental Cell, might open new avenues for understanding and perhaps treating fatty liver disease, which is the most common form of liver disease in the Western world and may... (Science Daily)
New Mechanism For Attentional Control In The Human Brain Discovered Dec 17, 2008
4, 2000) A new brain imaging study from the Institute of Psychiatry shows for the first time that brain abnormalities and social difficulties in schizophrenia are related. This exciting new study shows that. (Science Daily)
Three important questions can reduce your risk of stroke Dec 17, 2008
"Sometimes medication will need to be given, such as anti-platelet drugs or anti-coagulant drugs, to prevent blockage of a blood vessel. And if there are blood vessel abnormalities, which may lead to bleeding in the brain, then surgery may be needed," said Dr. Charles Siow, a consultant neurologist, also on staff at International Neuro Associates. Everyone has some stroke risk. (Jakarta Post, Indonesia -- Features)
Familys tale shared at fundraiser Dec 16, 2008
At the hospital in Medford, Postlethwait learned her daughter also had a brain abnormality, which could complicate surgery. The doctor said he could not treat Michelle, who was flown to Oregon Health and Sciences University in Portland. (Klamath Falls Herald & News, OR)
Success rate climbs for in vitro fertilization Dec 16, 2008
The report says the proportion of babies born with congenital abnormalities was not elevated among IVF-assisted births. Canadian women went through 8,278 cycles of IVF in 2006 in 25 fertility clinics across the country. (Globe and Mail -- National)
Colonoscopies miss cancers on the right side: study Dec 16, 2008
But it seems the screening measure is not very good at helping doctors see polyps or other potentially cancerous abnormalities on the right side of the body ... But Dr. Baxter said it's probably a variety of reasons, including the fact that abnormalities found on the right side are usually flatter and much harder ... Regardless, physicians and patients should be aware that being screened for colon cancer doesn't offer complete protection, and that improvements may be needed to ensure the test is... (Globe and Mail -- Business)
Cold Sore Virus Linked to Alzheimers Dec 16, 2008
However, despite enormous investment into research on the characteristic abnormalities of AD brain - amyloid plaques and neurofibrillary tangles the underlying causes are unknown and current treatments are ineffectual ... Together, these findings strongly implicate HSV1 as a major factor in the formation of amyloid deposits and plaques, abnormalities thought by many in the field to be major contributors to Alzheimers disease. (Newsmax)
Picture perfect: a child's courage Dec 15, 2008
"She was pregnant with him and didn't realize that he had a congenital heart abnormality," said Henrich. "When he was born, it was evident that he was not going to live very long. I'd gone as a friend just to take pictures of the baby being born, not realizing that the pictures that we took would be very significant. "Quinton ended up passing. (San Francisco Chronicle)
Patient Photos Spur Radiologist Empathy And Eye For Detail Dec 15, 2008
Incidental findings are unexpected abnormalities found on an image that may have health implications beyond the scope of the original exam. In order to assess the effect of the photographs on interpretation, 81 examinations with incidental findings were shown in a blinded fashion to the same radiologists three months later but without the photos. (Science Daily)
Amish gene saves from heart disease Dec 14, 2008
WASHINGTON: A rare genetic abnormality found in people in an insular Amish community protects them from heart disease, a discovery that could lead to new drugs to prevent heart ailments, US researchers said. About 5% of Old Order Amish people in Pennsylvanias Lancaster County have only one working copy rather than the normal two of a gene that makes a protein that slows the breakdown of triglycerides, a type of fat that circulates in the blood, the researchers said. (India Times, India)
How Warfarin Works Dec 13, 2008
g., or heart valve abnormalities). Individuals who take warfarin are accustomed to the periodic blood tests that are required to keep their bleeding time in a therapeutic range, but few really understand how this drug works. (Suite101.com)
Amish gene may provide heart protection Dec 13, 2008
WASHINGTON - A rare genetic abnormality found in people in an insular Amish community protects them from heart disease, a discovery that could lead to new drugs to prevent heart ailments, U.S. researchers said. About 5 percent of Old Order Amish people in Pennsylvania's Lancaster County have only one working copy rather than the normal two of a gene that makes a protein that slows the breakdown of triglycerides, a type of fat that circulates in the blood, the researchers wrote in the journal... (MSNBC -- Health)
Pilots May Face Greater Cancer Risk Dec 13, 2008
Blood samples from the participants were analyzed for DNA abnormalities, specifically the number of times pairs of chromosomes had changed places -- called translocations. Since translocations aren't eliminated from the blood like other forms of chromosomal abnormalities, they serve as a reliable indicator of cumulative DNA damage associated with radiation exposure, according to the study authors ... The findings suggest that experienced pilots may be exposed to biologically significant doses of... (MEDLINEplus)
Foods That Maximize Calcium's Healt... Dec 12, 2008
Silicon Deficiency may cause bone and connective tissue abnormalities, as well as hair loss, brittle nails, rapidly aging skin, and poor bone development Natural sources include oats, wine, high-fibre grains, nuts and seeds, oranges, cherries, raisins, almonds, peanuts, onions, raw cabbage, carrots, endive, eggplant, pumpkin, beets, celery, cucumber, honey, fish, corn, and apples. Manganese Aids mineral metabolism Natural sources include bran, bananas, egg yolks, whole grains, green leafy... (Suite101.com)
MRI Can Spot Presymptomatic Multiple Sclerosis Dec 12, 2008
The scans detected abnormalities similar to those that occur in MS. After the researchers confirmed these abnormalities were MS-related and ruled out other causes, they followed the patients for a number of years to find out if they developed the disease ... Brain scans showed that another 29 percent of patients had further abnormalities but still showed no symptoms ... "More research is needed to fully understand the risk of developing MS for people with these brain abnormalities, but it... (MEDLINEplus)
Brain scans may detect multiple sclerosis before symptoms appear Dec 12, 2008
Their scans showed signs of the kinds of abnormalities associated with MS - such as an increasing number of lesions in the white matter of the brain - that could not be explained by other diseases or causes. In addition to the patients who went on to develop symptoms, a further 30 per cent of patients' follow-up scans showed a progression of MS-style abnormalities over time, unaccompanied by symptoms. (Globe and Mail)
This little angel came to me for the right reason Dec 11, 2008
On June 10, Alyssa was taken to Childrens Hospital in Omaha, where a group of doctors determined that she has a rare chromosomal abnormality in which part of her second chromosome is missing. Chromosomes carry genetic information to every cell in the body. (Columbus Telegram, NE)
Gleevec* leads to longest survival reported for patients with life-threatening form of leukemia, 7-year IRIS data show Dec 11, 2008
(4) Almost all patients with CML have an abnormality known as the Philadelphia chromosome, which produces a protein called Bcr-Abl that causes malignant white blood cells to proliferate. (5) Gleevec(*), the first therapy to inhibit the activity of Bcr-Abl, revolutionized the treatment of Ph+ CML and is now the standard of care for this disease. (Canada Newswire)
Brain scans show MS signs years before it hits Dec 11, 2008
All had abnormalities similar to those seen in people with MS, but none had been diagnosed with the disease ... "More research is needed to fully understand the risk of MS for people with these brain abnormalities, but it appears that this condition may be a precursor to MS," Okuda, whose study appears in the journal Neurology, said in a statement ... He said further research is needed before doctors begin treating people with these pre-MS abnormalities. (MSNBC -- Health)
PTSD Risk Rooted in Stress and Genetics Dec 11, 2008
"We discovered a number of abnormalities in PTSD combat veterans not shared with their twins and . . . we infer that the abnormality was caused by combat," Pitman said. "One of these is increased heart rate response when the combat veteran is startled. Another example is loss of gray matter in the rostral anterior cingulated cortex, which plays a role in inhibiting the fear response.". (MEDLINEplus)
Achilles Heel Found In Cancer Cells Dec 11, 2008
31, 2004) Because up to 75 percent of breast cancer patients have an abnormality in a specific cell signaling pathway, drugs that target different molecules along that pathway may be especially effective for. (Jan. (Science Daily)
Epilepsy Drug Shows Potential For Alzheimer’s Treatment Dec 11, 2008
18, 2005) UCI researchers have determined that chronic nicotine exposure worsens some Alzheimer s-related brain abnormalities, contradicting the common belief that nicotine can actually be used to treat. . (Science Daily)
Brain scans predict MS, but should patients be told? Dec 11, 2008
A new study published online in this week's Neurology, the medical journal of the American Academy of Neurology, reports that a third of people who underwent an MRI (magnetic resonance imaging) for other brain-related problems, but whose scans also showed abnormalities suggestive of MS, went on to develop the chronic disease within an average of about five years ... The brain images of an additional 29% showed further abnormalities, but those people continued to live symptom-free. (USA Today)
Study of revlimid and vidaza in higher-risk MDS is well-tolerated and has high activity Dec 11, 2008
REVLIMID is also approved in Canada, the United States and Argentina for transfusion-dependent anemia due to low- or intermediate-1-risk MDS associated with a deletion 5q cytogenetic abnormality with or without additional cytogenetic abnormalities. REVLIMID has obtained Orphan Drug designation in the EU, U.S., Switzerland and Australia. (EurekAlert!)
Alzheimer's Disease Dec 10, 2008
By looking at images of the brain, doctors may be able to pinpoint any visible abnormalities. Researchers are studying whether brain scans can eventually be used to detect an increased risk of Alzheimer's in healthy people before symptoms begin. (CNN -- Health)
Headaches & Migraines Dec 10, 2008
MRI scans help doctors diagnose tumors, strokes, aneurysms, neurological diseases and other brain abnormalities. An MRI can also be used to examine the blood vessels that supply the brain. (CNN -- Health)
