Implanted pumps may help heal ravaged hearts Jul 22, 2008
A few thousand more try to buy time with "left ventricular assist devices" or LVADs, that take over the left ventricle's job of pumping blood through the body, powered by special batteries worn in a fanny pack. Early pumps were too big for many patients and wore out quickly, the longest lasting just over a year. (MSNBC -- Health)
Alaska newborns at higher risk for defects Jul 18, 2008
Chief among those were "atrial septal defects" and "ventricular septal defects" involving holes in the walls of the heart. But Alaska also posted higher than average rates of less common birth defects, such as cleft palates (two times the national average), fetal alcohol syndrome (four times the national average), and Hirschsprung's Disease, characterized by enlarged colons due to bowel obstructions (six times the national average). (Anchorage Daily News)
MRI scan may offer faster way to detect Alzheimer's Jul 14, 2008
Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database ... Ventricular enlargement may be an objective and sensitive measure of neuropathological change associated with mild cognitive impairment (MCI) and Alzheimer's disease (AD), suitable to assess disease progression for multi-centre studies ... This study compared (i) ventricular enlargement after six months in subjects with MCI, AD and normal... (CTV.ca)
Unsuspected Gene Mutation Found For Atrial Fibrillation Jul 13, 2008
13, 2006) Analysis of data from a registry of patients with left ventricular dysfunction indicates that height is an independent risk factor for an arrhythmia of the upper chambers of the heart, according to a. (Oct. (Science Daily)
Biological Marker For Alzheimer's Holds Promise For Earlier Diagnosis And Treatment Jul 13, 2008
Ventricular enlargement as a possible measure of Alzheimer's disease progression validated using the Alzheimer's disease neuroimaging initiative database. Brain, July 11, 2008 DOI. (Science Daily)
URMC, FDA to collaborate on national data repository for heart research Jul 13, 2008
The QT interval is a segment of an ECG recording that measures the process of ventricular repolarization the period between the heart's contraction and recovery phase ... Prolongation of the QT interval associated with episodes of fatal ventricular arrhythmias is a leading cause of removal of drugs from the market and was a leading impetus toward international collaboration to develop specialized studies to monitor the QT prolongation effects of new drugs. (EurekAlert! -- Business News)
Heartbeat Irregularity in Athletes Appears Benign Jul 13, 2008
Elite athletes usually have lower-than-normal heart rates when at rest, but when they are active, some develop rapid heart rhythms known as ventricular tachyarrhythmias. Studies suggest that up to 30 percent of high-level athletes show irregular ventricular rhythms ... Another feature of athlete's heart is an enlargement of the heart's main pumping chamber, known as left ventricular hypertrophy, or LVH.. (MEDLINEplus)
Gender Differences And Heart Disease Jul 4, 2008
For the first time, researchers have uncovered that women derive a lesser benefit than men from two common high-blood-pressure-lowering drugs losartan and atenolol for the reduction of left-ventricular hypertrophy (LVH) ... (June 21, 2007) Excessive body weight is associated with left ventricular hypertrophy, a thickening of the heart muscle in the left ventricle, the heart's pumping chamber. (Science Daily)
Have You Had a Stroke and Dont Even Know It? Jun 30, 2008
Risk factors such as cigarette smoking, diabetes, age, systolic blood pressure, hypertension, and cardiovascular conditions including atrial fibrillation (AF) and left ventricular hypertrophy were found to be consistent with the findings of this study. These risk factors had been isolated as a means of estimating the likelihood of stroke over a 10-year period of time in the Framingham Stroke Risk Profile. (MedHeadlines)
10 Percent Of Healthy People In Study Had Injury From 'Silent Strokes' Jun 30, 2008
The factors in the profile are age, systolic blood pressure, antihypertensive therapy, diabetes mellitus, cigarette smoking, cardiovascular disease, left ventricular hypertrophy and atrial fibrillation (AF). All the components of the Framingham Stroke Risk Profile were positively associated with an increased prevalence of SCI. For the first time, researchers found a significant correlation between AF and silent cerebral infarction. (Science Daily)
How To Save A Life With A Defibrillator Jun 28, 2008
When a patient suffers sudden cardiac death as a result of a heart attack, its not the heart attack itself that kills the person - its an abnormal rhythm (ventricular tachycardia or ventricular fibrillation) caused by damage to the heart muscle. A heart that is fibrillating beats ineffectively, like a bag of worms. (CBS News)
At war with Medicaid Jun 27, 2008
They don't really know what damage they do when they cut these services," she said. The family's latest battle with Medicaid is trying to get the state to pay for a upgrade to Keifer's bed that will help to keep him from developing a brain infection, Reynolds said. A ventricular shunt was placed in Keifer's brain at birth and without proper care and drainage it can become infected. "(The state) doesn't label it as medically necessary," she said. Those fighting to change the way Georgia Medicaid... (Athens Banner-Herald)
Electromagnetic Interference From Some Identification Devices May Pose Hazards To Medical Equipment Jun 26, 2008
Hazardous incidents included: total switch-off and change in set ventilation rate of mechanical ventilators; complete stoppage of syringe pumps; malfunction of external pacemakers; complete stoppage of renal replacement devices, and interference in the atrial and ventricular electrogram curve read by the pacemaker programmer. The median (midpoint) distance between reader and device at which all types of incidents occurred was 11. (Science Daily)
FDA Approves VELCADE(R) (Bortezomib) for Injection for Patients with Previously Untreated Multiple Myeloma Jun 21, 2008
Acute development or exacerbation of congestive heart failure, and new onset of decreased left ventricular ejection fraction has been reported, including reports in patients with no risk factors for decreased left ventricular ejection fraction. There have been reports of acute diffuse infiltrative pulmonary disease of unknown etiology such as pneumonitis, interstitial pneumonia, lung infiltration and Acute Respiratory Distress Syndrome in patients receiving VELCADE. Some of these events have... (PR Newswire)
Tim Russert: the details about what caused his death Jun 21, 2008
Impulses can become too fast (ventricular tachycardia) or chaotic (ventricular fibrillation). The latter happened to Russert. (Los Angeles Times)
Cajah's Mtn. donates land for EMS station Jun 21, 2008
"My only reservation has ever been (that), I don't like giving up our land," he said, adding that Courtner's presentation, which included the statistic that every minute a person's heart is in ventricular fibrillation the chance of death rises 10 percent, made him very much in favor of the proposal. Councilwoman Lois Andes also is excited about the prospect of having an ambulance stationed in the community. (Lenoir News Topic, NC)
Drug Effective against Heart-Lung Disorder Jun 21, 2008
Fainting was the most common adverse event in the bosentan group, and right ventricular failure was the most common in the placebo group. The findings are in the June 21 issue of The Lancet. (MEDLINEplus)
/R E P E A T -- The Montreal Heart Institute presents the findings of an international research project on congestive heart failure and atrial fibrillation/ Jun 19, 2008
Contrary to ventricular fibrillation (originating in the ventricles or lower chamber of the heart), atrial fibrillation is rarely fatal but does require treatment as it can lead to severe discomfort, heart failure or stroke. Atrial fibrillation affects roughly 2. (Canada Newswire)
Rhythm Control versus Rate Control for Atrial Fibrillation Jun 19, 2008
Methods We conducted a multicenter, randomized trial comparing the maintenance of sinus rhythm (rhythm control) with control of the ventricular rate (rate control) in patients with a left ventricular ejection fraction of 35% or less, symptoms of congestive heart failure, and a history of atrial fibrillation. The primary outcome was the time to death from cardiovascular causes. (New England Journal of Medicine)
Serum Sodium Predicts Mortality 10 Times Higher In PAH Patients Jun 18, 2008
3, 2006) Researchers have developed a simple, noninvasive way to measure right ventricular function in the heart to predict survival of adults who suffer from pulmonary hypertension. The research appears in. (Science Daily)
Russert's doctor: Medics tried to revive anchor Jun 18, 2008
His heart was beating then in a ventricular -- fine ventricular fib, and then it deteriorated. They shocked him again. (CNN -- US)
Towering figure in American journalism... Jun 14, 2008
But there was a rupture of cholesterol plaque in the wall of the coronary artery, which results in a heart attack, or what he called a fatal ventricular arrhythmia. Dr. Newman said the autopsy showed that Mr. Russert had an enlarged heart and significant coronary artery disease. (The Drudge Report)
Syntermed licenses Emory imaging technology for improved evaluation of heart failure patients Jun 13, 2008
CRT is used to improve heart function by restoring the correct mechanical sequence of heart contractions in patients with an irregular heartbeat, called left ventricular dyssynchrony ... "We designed this new nuclear imaging software to improve image clarity and to provide additional features and automation that should eliminate variations in interpretation and help physicians more accurately assess patients with left ventricular dyssynchrony." ... The most recent article, in the May 2008 issue... (EurekAlert! -- Business News)
Governor Rendell Signs Eight Bills Into Law Jun 12, 2008
The new law also says perfusionists may perform extracorporeal circulation, long-term cardiopulmonary support techniques, ventricular assistance, auto-transfusion, blood and blood component conservation techniques, blood and blood component management techniques, advanced life support and other related functions. They may also administer pharmacological and therapeutic agents and may perform anticoagulation monitoring and analysis, as well as blood gas and chemistry monitoring and analysis. (PR Newswire)
ECG Reading May Predict Death, Rehospitalization Risk Jun 12, 2008
They analyzed data from 2,962 patients hospitalized for heart failure who had a left ventricular ejection fraction (LVEF -- a measure of how well the left ventricle of the heart pumps with each contraction) of 40 percent or less. Of those patients, 1,641 had a normal QRS duration (less than 120 ms) and 1,321 had a prolonged QRS duration (120 ms or greater). (MEDLINEplus)
Could Heart Transplants Become A Thing Of The Past? Jun 8, 2008
Most of the devices help the left side of the heart, the powerful pumping chamber known as the left ventricle, so they re called left-ventricular assist devices or LVADs ... More on heart failure and left-ventricular assist devices ... The HeartMate left-ventricular assist device was approved for use in transplant candidates in 2001, and as a destination therapy for long-term use in 2003. (Science Daily)
New technique for heart attacks Jun 8, 2008
No measurement of infarct size of the heart attack or the function of the heart muscle (left ventricular function) was done. This means that they were unable to suggest subgroups in which the procedure may be beneficial. (NHS Choices)
Brain stem cells can be awakened, say Schepens scientists Jun 7, 2008
Until these studies, which were conducted in the adult brains of mice, scientists assumed that only two parts of the brain contained neural stem cells and could turn them on to regenerate brain tissue-- the subgranular zone (SGZ) of the hippocampus and the subventricular zone (SVZ). The hippocampus is responsible for learning and memory, while the SVZ is a brain structure situated throughout the walls of lateral ventricles (part of the ventricular system in the brain) and is responsible for... (EurekAlert!)
Is tap water safe for expectant mothers? Jun 4, 2008
Although the researchers found no direct link between the prevalence of any birth defect and the level of exposure, their calculations revealed that exposure to high levels of by-products substantially increased the risk of three common defects: ventricular septal defects (holes in the heart), cleft palate, and anencephalus (where neural development fails, resulting in the absence of a major portion of the brain, skull, and scalp). Exposure to total trihalomethanes above 20 g/L was associated... (innovations report)
'PLoS ONE' STUDY: A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice Jun 4, 2008
To assess left ventricular (LV) systolic and diastolic function as well as structure, we used in vivo M-mode and Doppler echocardiography to examine cardiac function in young (five month-old) control mice and 25 month-old control, CR and resveratrol fed mice ... End diastolic and systolic left ventricular (LV) diameter as well as anterior and posterior wall (AW and PW respectively) thicknesses were measured on line from M-mode images using the leading edge-to-leading edge convention ... Left... (USA Today -- Tech)
Black Athletes' Hearts May Differ from Those of Whites Jun 4, 2008
Such left ventricular hypertrophy, as it is called, is regarded as a sign of heart disease. But the study also challenges that idea -- at least as far as healthy young athletes are concerned, Friedman said. (MEDLINEplus)
New Data Offers Insights Into the Potential Role for TYKERB(R) (Lapatinib) in Non-Cytotoxic Chemotherapy-Based Treatment Regimens Jun 2, 2008
(1) Three patients in the combination arm had an asymptomatic decrease (greater than or equal to 20 percent) in left ventricular ejection fraction (LVEF) that was below the lower limit of normal. One patient had a smaller decline (3 times the upper limit of normal and total bilirubin >1. (PR Newswire)
Medical Center a leader in emergency resuscitation care May 30, 2008
Vassers began her journey with ventricular fibrillation, then crashed. Her heart stopped completely. (Univeristy of Chicago Chronicle, IL)
Ideal Treatment For Potentially Fatal Heart Condition Changes With Age, Research Shows May 28, 2008
In some cases, the dangerous heart rhythm stops on its own, but in others, it deteriorates into a fatal rhythm (ventricular fibrillation). Sudden death will then occur if the heart is not restarted with a defibrillator. (Science Daily)
Sleep Apnea Linked to Heart Risks in Children May 22, 2008
The researchers checked the children's levels of N Terminal pro B type Natriuretric Peptide (NTproBNP), a marker of ventricular strain, and C Reactive Protein (CRP), a marker for inflammation. Compared to a control group of children without OSA, 46 of the children with OSA had significantly higher levels of NTproBNP and of CRP. When the researchers checked 20 of the children in the OSA group three months after their surgery, their average levels of NTproBNP and CRP were less than the control... (U.S. News & World Report)
Cancer Drug May Help Patients With Heart-lung Disease May 22, 2008
Six out of nine had significant improvements in right ventricular ejection fraction, the ability of the heart to pump blood to the lungs ... They had an eight-percent improvement, on average, in right ventricular ejection fraction, as measured by three-dimensional echocardiography ... 3, 2006) Researchers have developed a simple, noninvasive way to measure right ventricular function in the heart to predict survival of adults who suffer from pulmonary hypertension. (Science Daily)
Catheter Ablation in Patients with ICDs May 22, 2008
To the Editor: We strongly support the rationale for ablation of ventricular tachycardia to reduce implantable cardioverter defibrillator (ICD) therapy, described by Reddy et al. (Dec. 27 issue),1 but would caution that risk stratification is essential to identify the subgroups of patients who would truly benefit from ablation in this setting. (New England Journal of Medicine)
Cancer Drug Helped in Pulmonary Hypertension Study May 22, 2008
Eight out of the first nine patients who took the drug saw improvements in their ability to exercise, and six out of nine had significant improvement in their right ventricular ejection fraction, which measures the heart's ability to pump blood to the lungs ... They saw an average 8 percent improvement in their right ventricular ejection fraction, a measure of the heart's pumping power. (MEDLINEplus)
ATHENA Clinical Results for Dronedarone (Multaq(R)) Highlighted at the World Cardiology Congress May 21, 2008
The atrial fibrillation or atrial flutter patients studied were either 75 years of age or over (with or without cardiovascular risk factor) or were below 75 years of age with at least one additional cardiovascular risk factor (hypertension, diabetes, previous cerebrovascular event, left atrium size greater than 50 mm or left ventricular ejection fraction lower than 40 percent). Patients suffering from decompensated heart failure were excluded from the study. (Canada Newswire)
Tasers can cause heart problems, inquiry hears May 21, 2008
Michael Janusz, a heart surgeon and professor of surgery at the University of British Columbia, told the inquiry that based on his study of available literature on taser use, almost all physicians would conclude that tasers can induce ventricular fibrillation. The hearing was told ventricular fibrillation is an extremely rapid rhythm in the heart's lower chambers, leading to ineffective contractions of the heart ... The hearing also heard from Charles Kerr, another UBC professor and a heart... (Globe and Mail)
Eisai's Commitment to Oncology Demonstrated by Clinical Data to be Presented at ASCO Annual Meeting May 16, 2008
Communication between the surgical resection cavity and the ventricular system should be avoided to prevent the wafers from migrating into the ventricular system and causing obstructive hydrocephalus. If a communication larger than the diameter of a wafer exists, it should be closed prior to wafer implantation. (PR Newswire)
Excess Drinking Boosts Cardiovascular Disease Risk May 16, 2008
The results showed that heavy drinking is associated with arterial stiffening and impaired left ventricular (LV) relaxation in males, and LV structural changes, including LV enlargement (hypertrophy), in females ... "The excessive consumption of alcohol causes significant arterial and ventricular stiffening and an enlarged heart; factors associated with poor cardiovascular outcomes in hypertensive populations," Mahmud said. (MEDLINEplus)
Heart Disease Starts Early in Life May 16, 2008
A second report on 824 young adults in the study (average age 36) concerned potentially dangerous changes in heart structure over time, such as left ventricular hypertrophy, or overgrowth of one heart chamber ... "In clinical medicine, we focus on patients who have documented heart disease and left ventricular hypertrophy," Ferdinand said. (MEDLINEplus)
Cardiac surgeon to join Jewish Hospital, U of L May 15, 2008
An expert in heart transplantation, ventricular assist devices and surgical management of heart failure, Dr. Slaughter earned his B.S. in civil engineering at and his M.D. at. He completed his residency in general surgery at and fellowship in cardiovascular and thoracic surgery at the. (Louisville Business First, KY)
Bayer Antibleeding Drug Takes Hit May 15, 2008
Of the 108 patients who died, the proportion with "cardiogenic shock, right ventricular failure, congestive heart failure, or myocardial infarction was higher in the aprotinin group than in the other two groups," the study said. Paul H;bert, critical-care physician at the Ottawa Hospital in Ottawa, Canada, and one of the study's lead authors, said clearly the drug shouldn't be used for high-risk cardiac surgery patients. (Wall Street Journal)
Three Abstracts of Human Studies On TASER Safety to be Presented At Heart Rhythm Society's 29th Annual Scientific Sessions May 15, 2008
Contrary to speculation that an electronic control device could induce ventricular fibrillation, the rhythm found in media-linked arrest-related deaths was primarily asystole which is associated with drug overdoses and cannot be induced with electrical stimulation; * There was no interference with pacemakers and implantable cardioverter defibrillators from TASER ECDs; and, * Real time ultrasound showed that even when electronic control device probes are placed across the heart, the ECD... (Primezone Releases)
Biomarkers to Predict Death from Cardiovascular Causes May 15, 2008
Methods We used data from the Uppsala Longitudinal Study of Adult Men (ULSAM), a community-based cohort of elderly men, to investigate whether a combination of biomarkers that reflect myocardial cell damage, left ventricular dysfunction, renal failure, and inflammation (troponin I, N-terminal pro brain natriuretic peptide, cystatin C, and C-reactive protein, respectively) improved the risk stratification of a person beyond an assessment that was based on the established risk factors for... (New England Journal of Medicine)
Boston Scientific Announces FDA Approval for New Devices to Treat Heart Failure and Sudden Cardiac Death May 14, 2008
-- Quick Convert(TM) -- provides the ability for patients to receive pacing therapy for ventricular tachycardias. -- Enhanced AV Search algorithm -- designed to minimize unnecessary right ventricular pacing. (PR Newswire)
Electrode Re-implantation Helps Some Parkinson's Disease Patients May 14, 2008
30, 2008) Despite the general success of left ventricular assist devices used in critically ill heart failure patients, implantation of these devices often leads to increased bleeding and a need for. (Mar. (Science Daily)
Thoratec Mechanical Heart May Stop Pumping Up Stock as Competition Emerges May 8, 2008
HeartMate is in a family of products known as left ventricular assist devices that are connected to the patient's heart during. These devices are generally used to help patients survive until a transplant organ becomes available. (Bloomberg -- US)
Left Cardiac Sympathetic Denervation for Catecholaminergic Polymorphic Ventricular Tachycardia May 8, 2008
NEJM -- Left Cardiac Sympathetic Denervation for Catecholaminergic Polymorphic Ventricular Tachycardia ... Left Cardiac Sympathetic Denervation for Catecholaminergic Polymorphic Ventricular Tachycardia ... Catecholaminergic polymorphic ventricular tachycardia is a potentially lethal disease characterized by adrenergically mediated ventricular arrhythmias manifested especially in children and teenagers. (New England Journal of Medicine)
Augmentation of J Waves and Electrical Storms in Patients with Early Repolarization May 8, 2008
2 Sporadic case reports and basic electrophysiological research have suggested a critical role of the J wave in the pathogenesis of idiopathic ventricular fibrillation. 3,4 Clinical evidence in support of an. (New England Journal of Medicine)
Sudden Cardiac Arrest and Early Repolarization May 8, 2008
Methods We reviewed data from 206 case subjects at 22 centers who were resuscitated after cardiac arrest due to idiopathic ventricular fibrillation and assessed the prevalence of electrocardiographic early repolarization ... Results Early repolarization was more frequent in case subjects with idiopathic ventricular fibrillation than in control subjects (31% vs. 5%, P<0 ... In eight subjects, the origin of ectopy that initiated ventricular arrhythmias was mapped to sites concordant with the... (New England Journal of Medicine)
Are you next? May 3, 2008
Many of these deaths are caused by ventricular fibrillation of the heart that occurs before the victim can reach an emergency room. Those that do, however, have an excellent prognosis. (Douglas Daily Dispatch, AZ)
FDA approves HeartMate II mechanical heart pump for heart-failure patients May 3, 2008
NEW YORK (April 25, 2008) -- Heart failure patients at NewYork-Presbyterian Hospital/Columbia University Medical Center were among the first to be implanted with the HeartMate II LVAS (Left Ventricular Assist System) -- a miniature mechanical pump that helps weak hearts pump blood -- that has now received approval by the FDA as of April 21 for broad use as bridge to transplantation. As part of clinical trials leading to approval, 22 patients received the new device at... (EurekAlert! -- Business News)
Evidence that stun guns may stimulate the heart May 3, 2008
The evidence that stun guns do not stimulate the heart is based on theoretical studies [that] suggest that stun guns cannot deliver the amount of energy required to stimulate the heart or cause ventricular fibrillation ... In one study, swine blood pressure was abruptly lost after discharge of a stun gun, and another study reported the deaths of 2 animals caused by ventricular fibrillation immediately after the stun gun discharge. (EurekAlert!)
Cause of Childhood-Onset Cardiac Hypertrophy May 2, 2008
We also sequenced PRKAG2 and LAMP2, which encode metabolic proteins; mutations in these genes can cause early-onset ventricular hypertrophy. Results We identified mutations in 25 of 51 affected children without family histories of cardiomyopathy and in 21 of 33 affected children with familial cardiomyopathy. (New England Journal of Medicine)
Patients Receive Heart Valve Replacements Without Surgery Using High-tech Device Apr 21, 2008
All of the patients are recovering and are expected to go home today," said Dr. Ziyad M. Hijazi, director of the Rush Center for Congenital and Structural Heart Disease, chief of the section of pediatric cardiology and professor in the departments of pediatrics and internal medicine at Rush University, Chicago. "Patients with congenital right ventricular outflow tract problems typically face the burden of multiple open-heart surgeries throughout their lives, either to replace their 'native'... (Science Daily)
Heart Support Apr 19, 2008
Thoratec technology chief Victor Poirier devised the first ventricular assist device (VAD) in 1975, when he was an engineer at research and development company Thermo Electron (nyse: - - ) ... Thoratec grossed 60% of its $235 million in revenue from its ventricular assist devices last year. (Forbes -- Business)
Travelers to trim positions in Fall River, 3 other posts Apr 15, 2008
Boston Scientific gets OK in Japan for heart device Medical-device maker said the Japanese government approved its Acuity Steerable ventricular lead, an electrode system that can be placed within the heart by snaking it through blood vessels. The Natick company also received reimbursement approval for the lead from the National Health Insurance System and plans to launch it immediately in Japan. (Boston Globe)
Dispatcher, ambulance shortages slow response Apr 15, 2008
The most common form of cardiac arrest is ventricular fibrillation, which is characterized by a rapid, irregular heart rhythm. Delayed responses increase the risk of brain injury and death. (San Francisco Chronicle)
Protect yourself against poisoning from the deadly carbon monoxide gas Apr 14, 2008
Most CO poisoning deaths are the result of a heart dysfunction known as ventricular fibrillation. Not all victims of CO poisoning will develop these symptoms and some victims may not elicit any. (Lompoc Record, CA)
Genetic Test Offers Clues About Cardiac Hypertrophy In Children Apr 14, 2008
21, 2007) Excessive body weight is associated with left ventricular hypertrophy, a thickening of the heart muscle in the left ventricle, the heart's pumping chamber. The largest study of its kind helps explain. (Science Daily)
CV Therapeutics and Astellas Announce FDA Approval for Lexiscan(TM) (regadenoson) Injection Apr 11, 2008
Less frequent side effects reported in patients administered Adenoscan include second and third degree AV block, fatal cardiac arrest, ventricular tachycardia and nonfatal myocardial infarction. For full prescribing information, please visit. (PR Newswire)
Millennium Announces VELCADE(R) (Bortezomib) for Injection First-Quarter 2008 U.S. Net Sales Apr 10, 2008
Acute development or exacerbation of congestive heart failure, and/or new onset of decreased left ventricular ejection fraction has been reported, including reports in patients with few or no risk factors for decreased left ventricular ejection fraction. There have been rare reports of acute diffuse infiltrative pulmonary disease of unknown etiology such as pneumonitis, interstitial pneumonia, lung infiltration and Acute Respiratory Distress Syndrome in patients receiving VELCADE. Some of these... (PR Newswire)