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We have made significant progress in advancing NP2, the first of several product candidates, towards the clinic in a timely and effective manner, said Michael Christini, President of Diamyd, Inc. With NP2, we have laid the groundwork for the rapid development of additional drug candidates such as the NTDDS-GAD product to treat pain in diabetes ... In addition, our Diamyd Inc. lab facilities and expertise in manufacturing and preclinical areas have been fully used to move the company s lead... (BusinessWire)
Advice for O.J. Simpson regarding 'If I Did It' book Aug 22, 2007
Oh sure, he can gad around second-rate golf courses saying hi to fellow duffers and seeming to be living the high life, but he is in fact the most ostracized man in America and may remain so for a long time. My advice to O.J., author to author: Go ahead and write a book. (Fox News)
Pfizer Inc UK Regulatory Announcement: Pfizer Says Growth in Phase II Portfolio Supports Goal of Tripling Phase III Portfolio by 2009 Aug 7, 2007
In neuroscience, Pfizer received approval during the period for Lyrica s fibromyalgia indication, an important line extension in the U.S. Lyrica is currently in Phase III testing for epilepsy monotherapy and Generalized Anxiety Disorder (GAD) in the U.S., as well as Phase II for restless leg syndrome ... Pfizer also continues work on alpha-2-delta compounds for patients with neurological disorders, and it is proceeding with broad confirmatory development of PD-332334, now in Phase II, for the... (BusinessWire)
FEATURE-Spy recalls secret mission saving Ethiopian Jews Aug 1, 2007
JERUSALEM, Aug 1 (Reuters) - While other Israeli spies spent the early 1980s stalking Arab foes through Europe, Gad Shimron was deep in Africa on a secret mission to save lives. Thousands of Ethiopian Jews had fled the Eritrean conflict to neighbouring Sudan, only to be stranded in teeming camps. (AlertNet)
'Jihad bible' author stirs up storm Jul 27, 2007
Photograph: Makram Gad Alkareem/AFP/Getty Images. In a prison cell south of Cairo a repentant Egyptian terrorist leader is putting the finishing touches to a remarkable recantation that undermines the Muslim theological basis for violent jihad and is set to generate furious controversy among former comrades still fighting with al-Qaida. (Guardian Unlimited -- World)
Breast cancer study offers hope to BRCA carriers Jul 16, 2007
Dr. Gad Rennert, of the Rappaport Medical Faculty at the Technion-Israel Institute of Technology in Haifa, along with collaborators at the University of Toronto, focused on an Israeli population because 60 percent of that country's population is Ashkenazi, who have a higher prevalence of the BRCA genes than non-Ashkenazis. A BRCA 1 or BRCA 2 mutation was identified in 10 percent of women in the study who were of Ashkenazi heritage, Rennert said. (Newsday -- Health)
BRCA Gene Does Not Increase Breast Cancer Death, New Study Jul 14, 2007
The study is published in the New England Journal of Medicine (NEJM) and was the work of Dr Gad Rennert, of Clalit Health Services, National Cancer Control Center and Department of Community Medicine and Epidemiology, Carmel Medical Center, Haifa, Israel and colleagues also in Israel and Canada ... "Clinical Outcomes of Breast Cancer in Carriers of BRCA1 and BRCA2 Mutations." Rennert, Gad, Bisland-Naggan, Shantih, Barnett-Griness, Ofra, Bar-Joseph, Naomi, Zhang, Shiyu, Rennert, Hedy S., Narod,... (Medical News Today)
Researchers find good news for some breast cancer sufferers Jul 13, 2007
Gad Rennert of the Technion-Israel Institute of Technology's Rappaport Medical Faculty, "we can offer the reassurance that in spite of a bad profile of prognostic factors in carriers, their survival is actually at least as good as for noncarriers.". Rennert, Dr. Steven Narod of the University of Toronto and colleagues published their findings in the July 12 issue of the New England Journal of Medicine. (Jerusalem Post)
IDF soldier killed in central Gaza Strip during clash with militants Jul 13, 2007
Hamas's armed wing, the Izz el-Deen al-Qassam Brigades, said its militants ambushed the IDF troops as they entered the camp. When the militants approached the troops, an Israel Air Force aircraft fired on them and identified hitting them, IDF sources said. (Yahoo News -- Mideast Conflict)
Breast Cancer Genes Don't Raise Tumor-Linked Death Risk Jul 12, 2007
"Our main finding of similar -- or even better -- survival of the carriers is in contrast to some, but not all, of the former publications on the subject," noted study author Dr. Gad Rennert, of the Clalit National Cancer Control Center and Carmel Medical Center in Haifa, Israel. "However, we employed a 'clean' design which was not possible for other research groups and therefore our study results come closer to 'truth' than any other study on the subject.". (Forbes)
Bad genes don't shorten cancer survivors' lives: study Jul 12, 2007
"But little is known about the influence of a BRCA1 or BRCA2 mutation on the natural history of breast cancer or the response to treatment," Gad Rennert of the National Cancer Control Centre in Haifa and colleagues wrote. They studied women treated at 22 hospitals in Israel. (Globe and Mail)
Genes May Not Affect Odds Jul 12, 2007
"As a result of the study, we can offer to the medical community the assurance that there is no difference in the prognosis between carriers and noncarriers," said Gad Rennert, the study's lead author and chairman of the medical faculty at Israel's Technion university in Haifa. The finding is somewhat of a surprise, as carriers of the mutant genes tend to develop a more virulent form of the disease that strikes before age 50, and can be resistant to certain types of treatments. (Wall Street Journal)
Clinical Outcomes of Breast Cancer in Carriers of BRCA1 and BRCA2 Mutations Jul 12, 2007
Gad Rennert, M.D., Ph. D., Shantih Bisland-Naggan, M.P.H., Ofra Barnett-Griness, Ph. (New England Journal of Medicine)
Breast Cancer Prognosis Not Affected by BRCA Status Jul 12, 2007
Gad Rennert, M.D.Carmel Medical Center ... Some features of breast cancer in women with a BRCA1 mutation suggest that it has a poor outcome, but little has been known about the influence of such mutations on the natural history of breast cancer or the response to treatment, wrote Gad Rennert, M.D., of Carmel Medical Center here, and colleagues in the July 12 issue of the New England Journal of Medicine. (MedPage Today)
U-M, Israeli scientists report major advance in search for genes associated with colon cancer Jul 9, 2007
Senior author Gad Rennert M.D., Ph. D., of the Carmel Medical Center and the B. Rappaport Faculty of Medicine at Technion in Haifa, Israel, says The study of populations in Israel has been shown to be exceptionally fruitful in contributing to knowledge about the genetics of leading cancers. (EurekAlert!)
Will big U.S. job gains raise inflation risks? Jul 7, 2007
Will big U.S. job gains raise inflation risks. - Eye on the Economy - MSNBC.com. (MSNBC -- Terrorism)
Naveen against decrease of medical seats in Orissa Jul 7, 2007
In view of the deficiencies, the Ministry gad decided not to recommend renewal of permission for admission of fresh batch of students against the last academic session's increased intake from 107 to 150. Patnaik's letter seemed to be silent about the deficiencies pointed out by the Medical Council team. (KalingaTimes)
Egypt says mummy is Queen Hatshepsut Jun 29, 2007
Egyptian molecular geneticist Yehia Zakaria Gad, who is on Hawass' team, said DNA bone samples were obtained from the mummy's hip bone and femur ... The preliminary results were "very encouraging," Gad said. (Herald Online, SC -- Health)
Parkinson's Gene Therapy Breakthrough May Enter Clinical Trials by Year-End Jun 27, 2007
They used a harmless virus called an adeno-associated virus to transport a gene that codes for the enzyme glutamic acid decarboxylase (GAD) into the neurons of the subthalamic nucleus. The gene prompted these subthalamic cells to produce gamma-aminobutyric acid (GABA), the brain's primary inhibitory neurotransmitter, which made them settle down and restored normal motor function. (Scientific American)
Egypt unveils mummy discovery Jun 27, 2007 First-Ever Gene Therapy Treatment Shows Promise for Parkinson's Jun 23, 2007 First ever study for Parkinsons in humans successful Jun 23, 2007 Lancet study shows gene therapy for Parkinson's disease is safe and some patients benefit Jun 23, 2007 Gene therapy treatment offers Parkinson's relief Jun 22, 2007 1st Gene Therapy Trial Effective Against Parkinson's Jun 22, 2007 A Gene Fix for Parkinson's? Jun 22, 2007 Analysis: Parkinson's great genetic hope? Jun 22, 2007 Gene breakthrough against brain diseases Jun 22, 2007 Old Forge graduate wants to make each day count Jun 8, 2007 This Week's Economic Roundup Jun 3, 2007 Clinical Trials Update: May 29, 2007 May 30, 2007 Obituary: Christopher Hurst May 30, 2007 'The Valet' ***1/2 May 25, 2007 FOX Announces 2007-2008 Season Line Up May 18, 2007 MediciNova Announces First Quarter 2007 Financial Results May 11, 2007 'Valet's' a funny tangle (Kelly Jane Torrance) May 11, 2007 Florida ranks fourth in online job vacancies Apr 3, 2007 Two strikes and you're out? Mar 29, 2007 Around the Valley Mar 22, 2007 Death ends ERAU student's dream Mar 15, 2007 Egypt: Don't Talk About the (1967) War Mar 11, 2007 These teenage misfits hit a new low Mar 3, 2007 United protest at West Bank wall Feb 24, 2007 Offering Hope: Frozen egg results in pregnancy, team of local doctor says Feb 21, 2007 MediciNova Reports 2006 Financial Results Feb 16, 2007 Ghana Actors Guild re-enact Nkrumah's release from prison Feb 14, 2007 Sanofi-aventis 2006: In a Difficult Environment, Another Year of Growth in Adjusted EPS Excluding Selected Items Feb 13, 2007 Valentine's Day gifts show your heart's desire you have a heart Feb 9, 2007 Oral Insulin To Prevent Type 1 Diabetes Tested In Study Feb 3, 2007 Different Strokes Jan 31, 2007 New Review May Ease Worries Of People With Disabling Anxiety Disorder Jan 30, 2007 I'm a latte drinking, sushi eating, body pierced, NY Times reading liberal, so I know something about global warming! Let me tell you this: there is so much hot air coming out of this argument today, I could cook my soy hot dogs! More... Jan 26, 2007 MediciNova Initiates Phase II Clinical Trial for MN-305, a Novel Treatment for Insomnia Jan 23, 2007 Generalized anxiety disorder often goes undiagnosed Jan 11, 2007
DNA bone samples taken from the mummy's pelvic bone and femur are being compared to the mummy of Queen Hatshepsut's grandmother, Amos Nefreteri, said Egyptian molecular geneticist Yehia Zakaria Gad, who was part of Hawass' team. While scientists are still matching those mitochondrial DNA sequences, Gad said Wednesday that preliminary results were "very encouraging.". (Herald Online, SC -- Health)
Parkinsons Disease Treatment with Gene Therapy Shows Promise Jun 25, 2007
In this case, the "gene of interest" is the glutamic acid decarboxylase (GAD) gene. "GAD makes a chemical called GABA, a major inhibitory neurotransmitter in the brain that helps 'quiet' excessive neuronal firing," explains Dr. During, the senior author of the current study, who worked on this research while at Weill Cornell ... The researchers' bold idea: to insert the GABA-producing gene GAD back into an area of the brain called the subthalamic nucleus, a key regulatory center within this... (SeniorJournal.com)
What is new is the gene that is carried into the cell, known as glutamic acid decaboxylase, or GAD. The GAD gene makes a chemical called GABA, which prevents trigger-happy neurons in the brain from firing excessively and bringing about symptoms. "GABA is the main inhibitor in the brain," Kaplitt explained to ABCNEWS.com. (ABC News)
The GAD genes produce GABA, a neurotransmitter that helps quiet overactive neuronal firing in the brain. After about three months of the treatment the symptoms like tremors, stiffness and trouble walking started improving by an average of 25% and lasted for up to a year and even four years in some. (The Money Times)
One woman and 11 men received a surgical infusion of fluid containing a viral vector and genes for a protein called GAD, glutamic acid decarboxylase. This enzyme is critical in controlling a neurotransmitter called GABA. In Parkinsons, GABA is reduced in an area of the brain called the subthalamic nucleus. (EurekAlert!)
In the latest attempt, the gene that was delivered to the Parkinson's patients controls production of an enzyme called GAD or glutamic acid decarboxylase. GAD controls a neurotransmitter or message-carrying chemical called GABA.. (Scientific American)
Participants were divided into three groups of four and given low, medium or high dose injections of the glutamic acid decarboxylase (GAD) gene directly into brain cells. The gene, which is involved in dopamine production, was transferred to the cells using an adeno-associated virus. (Health-Finder)
As an alternative, a team led by Michael Kaplitt and Matthew During of Weill Medical College of Cornell University in New York City want to add a gene called glutamic acid decarboxylase (GAD) to cells in the subthalamic nucleus, which is hyperactive in Parkinson's patients ... Working with others in New York City, New Zealand, and at Neurologix, a company in Fort Lee, New Jersey, that Kaplitt and During founded, the team first hitched the GAD gene to a harmless virus, called adeno-associated... (Science Now)
The GAD genes produce GABA, a neurotransmitter that helps quiet overactive neuronal firing in the brain. The hyperactive firing happens in Parkinson's patients and makes it difficult to coordinate movement. (United Press International)
"The research team, from the New York-Presbyterian Hospital/Weill Cornell Medical Centre and the New Jersey-based company Neurologix, report their findings in today's edition of The Lancet.Parkinson's occurs when the brain cells - neurons - that release the messenger chemical known as dopamine die. Protein deposits also form in the brain, and levels of another messenger chemical called GABA - which calms overexcited brain cells - drop.The study, begun in 2003, was carried out on 11 men and one... (Telegraph.co.uk)
Jamal Rashad Aldubayan, Kayla M. Aston, Robert Barcola, Nicole Rose Baron, Alexa Elizabeth Barsigian, Angela Theresa Berta, Stephen Thomas Bieryla, Ashley Lyn Brown, Nastasha Elena Burdyn, Christopher Chesniak, Ronald Coles, Auralee Collins, Bryan Cristiano, Michael S. Cusumano, Tiffany Amber DeMark, Amy Nicole Dolinish, Ryan Michael Ermel, Breah D. Evans, Zachary Evarts, Crystal Fausnaught, Scot M. Felkowski, Michael J. Finnerty, Ashley Fuller, Hazem M. Gad, Jillian Geiger, Anthony Neil... (Scranton Times, PA)
The gains are the result of an ongoing boom in health care, IT, business management, and other industries and occupations that advertise heavily online, according to Gad Levanon, a Conference Board economist. Consumer Confidence Rebounds. (Fox News)
Generalized Anxiety Disorder (GAD). Crohn's Disease. (Health-Finder)
Christopher's early publishing was centred on the Nordic countries to whose literature he had been introduced by Finn Gad, author of A History of Greenland, and on Africa - important colonial memoirs and a series of books on African politics. Some of these were passed on by large firms, such as Longman, who needed to protect their profitable growth in educational publishing in Africa. (Guardian Unlimited -- Books)
text size Lowly parking attendant Francois 9Gad Elmaleh) and his supposed supermodel girlfriend (Alice Taglioni) in The Valet ... Cast: Gad Elmaleh, Alice Taglioni, Kristin Scott Thomas ... The title character is Francois (Gad Elmaleh), a nebbishy parking attendant in love with a girl who's way out of his league. (AZCentral -- Entertainment)
Back in Pittsburgh, Chuck has a new coworker in RYAN CHURCH (Josh Gad, "Mary and Joe"), the overstressed news director ... CAST: Kelsey Grammer as Chuck, Patricia Heaton as Kelly, Fred Willard as Marsh, Josh Gad as Ryan, Ty Burrell as Gary, Laura Marano as Gracie ... News Director DAN DELGADO is fit to be tied as his beloved journalistic standards go out the window. (FOX19.com, OH)
MN-305 is a novel, potent and highly selective serotonin 5-HT1A receptor agonist under development for the treatment of anxiety disorders, beginning with Generalized Anxiety Disorder (GAD). In June 2006, MediciNova completed a randomized, double-blinded, placebo-controlled multi-center Phase II/III clinical trial of 416 subjects with GAD in the United States ... Within this trial, significant improvements in insomnia were noted in GAD patients treated with 0. (Primezone Releases)
He's likably played here by Gad Elmaleh as a nice guy who visits his parents and just wants to settle down with his girlfriend. But Emilie (Virginie Ledoyen, "The Beach") is too wrapped up in the struggling bookstore she owns to think about marriage. (Washington Times)
"Looking at the ads rate (the number of ads per 100 persons in the local labor force) is a good way to see how various areas in Florida compare," says Gad Levanon, an economist at The Conference Board. Nationally, the ads rate is 2. (Orlando Business Journal)
Godzilla wrote on March 28, 2007 5:39 PM:"For gad sakes Hank, get a real job. Are we to assume that you were so gullible to think you could actually live on those wages earned in a grocery store? This is the type of job for teanagers and mothers with extra time on their hands, this is not and will never be a career type position. Its a step up to better things type job, cry me a river:(". ExStoreMgr wrote on March 28, 2007 6:06 PM:"Oh... this is such a difficult argument because both sides have... (North County Times)
If you or someone you know has seen a century or more of life, contact Michele Gad at the Region 10 Area Agency on Aging at 249-2436, ext. 15, for more information. (Montrose Daily Press, CO)
Long's beats lived on, however, as roommate Gad Wavomba blasted his album "Mic Etiquette" to students on the Embry-Riddle Aeronautical University campus Wednesday. It was a fitting tribute for Long, who wanted to produce music professionally. (Daytona Beach News Journal)
"Egypt and the U.S. have struck a back channel deal by which Egypt plays a regional role designed by the U.S. in return for casting a blind eye to the regime's domestic politics and practices," says Emad Gad, analyst at Al Ahram Center for Political and Strategic Studies and editor of the monthly "Israeli Digest." So, Gad says, the challenge for the regime is to find a formula that will save face in the public eye. "The regime has given the green light to the government-controlled media to... (Time.com)
wrote on March 02, 2007 10:08 AM:"same as Jim Galewski. Don't you guys have anything better to do than bellyache about kids and money all the time? Get a life... Gad, it must be boring to be so grouchy and crotchety all the time...". Frank Schnurstein wrote on March 02, 2007 8:23 AM:"Both points well made and well said.". (Winona Daily News, MN)
Gad Miron, an Israeli, stood looking down the hillside at the barrier with his wife, Sara, a maths teacher, who said: "It really hurts us that we are still occupying the territories. But we have no leadership to change the situation. There is a deep fear that started with the Holocaust and this fear is behind the actions of the government. We cannot be delivered of this fear," she said. "But we are putting ourselves in danger with what we are doing.". (Guardian Unlimited -- World)
Advertisement The recipient is in the third month of her pregnancy, which appears to be progressing normally, said Dr. Gad Lavy, medical director and founder of the Stamford-based for-profit treatment center on Summer Street. Doctors would not release the pregnant woman's identity but said she is a Fairfield County resident. (Stamford Advocate)
A novel, potent and highly selective serotonin 5-HT1A receptor agonist, MN-305 was under development for the treatment of anxiety disorders, beginning with Generalized Anxiety Disorder (GAD) ... Based on an unexpected finding in the GAD studies, MediciNova initiated a Phase II study in insomnia subjects in January, 2007. (Primezone Releases)
Accra, Feb. 13, GNA - The Ghana Actors Guild (GAD) on Tuesday re-enacted the release of Osagyefo Dr. Kwame Nkrumah from prison following his arrest on January 13, 1948 for calling for positive action against the then colonial government of the Gold Coast ... Mr. Samuel Odoi, President of GAD told the GNA after the play that GAD would also re-enact the February 28, 1948 shooting incident on February 28, 2007 between the National Theatre and the Castle Junction, where the incident that led to the... (Ghana Web, Ghana)
Central nervous system: Saredutant (SR48968) is a NK2 receptor antagonist in phase III for the treatment of Major Depressive Disorder (MDD) and General Anxiety Disorder (GAD) ... Amibegron (SR58611) is a selective beta 3 agonist also in phase III in MDD and GAD. The company is currently conducting six phase III trials in MDD as well as five trials in GAD. The total number of patients enrolled exceeds 4,500. (PR Newswire)
For a $5,000 diamond sold, the company would give about $240 to Adopt-a-Minefield, and that amount of money pays to have more than 1,500 square feet cleared of mines, according to Gad Zak, president of Igloo Diamonds. The bigger the diamond sold, the bigger the minefield cleared. (Orlando Sentinel)
These autoantibodies to glutamate decarboxylase (GAD), IA-2, and to insulin itself indicate a greater risk for developing type 1 diabetes. For a person with high-risk genes and all three antibodies, the risk of developing diabetes in the next 5 years is greater than 50 percent. (Science Daily)
Alighting in Paris, he took undemanding, lucrative jobs in finance, and married a Danish woman, Mette Sophie Gad, whom he bullied psychologically and, perhaps, physically ... But when it came to active dramatizing, in the face of a projected, despised bourgeois society, Gauguin blazed a way for Picasso, his fellow artistic and sexual conquistador, and for every artist, to this day, who has adopted an attitude of renegade or subversive temerity. (New Yorker)
"GAD is a very common and extremely disabling condition and psychological therapies are a popular and widely used treatment for anxiety disorders," said lead author Vivien Hunot, Ph. D. "The review showed that psychological therapy using a cognitive behavioral therapy approach is effective for GAD." ... "I think it a hopeful message that there is a brief structured therapy that works for people with GAD.". (Science Daily)
" GAD wrote on January 25, 2007 12:18 PM:"TO: PRISCILLA ROBERTS. I moved to Temecula in 1992. I have witnessed tremendous growth in this area. (North County Times)
MN-305 is a potent and highly-selective full agonist at the serotonin 5-HT1A receptor under development both for the treatment of insomnia as well as for anxiety disorders such as Generalized Anxiety Disorder (GAD) ... MediciNova intends to explore the potential of MN-305 as a treatment for insomnia based on clinical observations of a beneficial therapeutic effect on insomnia in patients with GAD. In a recently completed Phase II/III randomized, double-blind, placebo-controlled clinical trial of... (Primezone Releases)
If you or someone you love worries excessively about everyday problems, it could be a sign of generalized anxiety disorder (GAD). According to the National Institute of Mental Health, nearly 7 million people are affected with GAD. Common sense would dictate that millions more go undiagnosed and untreated ... People with GAD worry that the worst will happen; they are unable to let the feeling go and never seem to be able to relax. (Scripps Howard News Wire)
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