The World's Longevity Secrets Jul 6, 2008
While scientists have known for decades that animals can live longer when they eat less, researchers are just beginning to determine the extent of the impact caloric restriction can have on humans. A study published in 2006 in the Journal of the American College of Cardiology, for instance, found that the hearts of people who followed a low-calorie, Mediterranean diet resembled those of younger people. (Forbes)
Resveratrol, Found In Red Wine, Wards Off Effects Of Age On Heart, Bones, Eyes And Muscle Jul 4, 2008
"Research is attempting to understand the process of aging and to determine how interventions can influence this process. Dietary restriction has well-documented health benefits in mammals, and the study of possible mimetics of it, such as resveratrol, are of great interest," said NIA Director Richard J. Hodes, M.D. "Resveratrol has produced significant effects in animal models, now including mice, where it mimics some, but not all, consequences of caloric restriction. Its effects in humans... (Science Daily)
Proteins Could Relate To Increased Longevity In Women Jul 1, 2008
Combined Effect of Gender and Caloric Restriction on Liver Proteomic Expression Profile. J. Proteome Res. (Science Daily)
Red Wine A Weapon In Battle Of The Bulge Jun 19, 2008
In previous research, Wabitsch and his colleagues had found that the resveratrol protected lab mice fed a high-calorie diet from the health problems brought on by obesity by mimicking the effects of caloric restriction. So the next step, they thought, was to see if the substance could mimic the effects of caloric restriction in human fat cells by changing them ... She says that not enough is known about caloric restriction. (CBS News)
Hormone Disorder May Contribute To Lack Of Menstruation In Teenage Athletes Jun 18, 2008
Evidence suggests that intense exercise associated with caloric restriction, and therefore a state of energy deficit, is most responsible for menstrual irregularities among athletes. "The hormonal factors that link energy deficit and the stopping of periods in athletes are not well characterized," she said. (Science Daily)
Menstruation Cessation in Female Teen Athletes May Be Caused by Hormone Jun 18, 2008
Intense exercise and caloric restriction, which cause an energy deficit in the body, are thought to cause the menstrual irregularities in athletes. Amenorrhea can cause infertility and early onset of low bone density, which may increase the risk of broken bones. (MEDLINEplus)
New KLRI Reports Shows Longevity Science Moving Beyond Studying the Obvious to the 'Downward Spiral' Paradigm in the Aging Process Jun 11, 2008
Animal studies have found that dramatically reducing food intake, or caloric restriction, can significantly increase longevity ... Along with oxidation and caloric restriction, the impact of hormones is a key focus in longevity science. (PR Newswire)
Study: Red wine chemical protect hearts of mice as well as diet Jun 11, 2008
Now scientists say resveratrol, the chemical in red wine thought to confer much of the drink s health benefits, protects the hearts of mice as well as caloric restriction. Resveratrol really mimics some aspects of caloric restriction, said Tomas Prolla, a UW-Madison professor of genetics and an author of the study ... Resveratrol blocked age-related changes in 92 percent of the genes in the heart, similar to the 90 percent improvement found in mice on caloric restriction. (La Crosse Tribune, WI)
Can Red Wine Help You Live Longer? Jun 10, 2008
Specifically, the results observed in the resveratrol-fed mice mimicked those often seen with caloric restriction the practice of cutting 20%-30% of calories out of one's typical diet in an effort to improve health and prolong life. Numerous studies have linked caloric restriction to a longer, healthier life. (CBS News)
New science, drugs, may lengthen human life... Jun 5, 2008
Sinclair said that based on Weindruch's work, he set out a decade ago to find the genes involved in caloric restriction and find a pill that can provide the benefits "without you feeling hungry all the time.". He described how his research found that mice given large doses of resveratrol "live longer, they're almost immune to the effects of obesity. They don't get diabetes, cancer, Alzheimer's as frequently. We delay the diseases of aging.". (The Drudge Report)
Red Wine Compound Helps Heart, May Slow Aging Jun 5, 2008
Resveratrol mimics effects of caloric restriction to extend life spans in mice ... Tests in mice revealed that low doses of resveratrol mimic the effects of caloric restriction, diets with 20 percent to 30 percent fewer calories than a typical diet that have been shown to extend life span ... "This brings down the dose of resveratrol toward the consumption reality mode. At the same time, it plugs into the biology of caloric restriction," co-senior author Richard Weindruch, a professor of... (Health-Finder)
Substance in red wine found to keep hearts young Jun 5, 2008
Specifically, the researchers found that low doses of resveratrol mimic the heart-healthy effects of what is known as caloric restriction, diets with 20 to 30 percent fewer calories than a typical diet. The new study is important because it suggests that resveratrol and caloric restriction, which has been widely studied in animals from spiders to humans, may govern the same master genetic pathways related to aging ... "Caloric restriction is highly effective in extending life in many species. If... (EurekAlert!)
Red wine 'can prevent ageing' Jun 5, 2008
A glass of red wine, or food supplements containing even small doses of resveratrol, were likely to represent a "robust intervention in the retardation of cardiac ageing, according to the researchers at Wisconsin-Madison University. "There must be a few master biochemical pathways activated in response to caloric restriction, which in turn activate many other pathways. And resveratrol seems to activate some of these master pathways as well," Prolla said. The results of the study have been... (India Times, India -- Health/Science)
Red wine may protect heart from agings toll Jun 4, 2008
Resveratrol at low doses can retard some aspects of the aging process, including heart aging, and it may do so by mimicking some of the effects of caloric restriction, which is known to retard aging in several tissues and extend life span, added Prolla, whose study was published in the scientific journal PLoS ONE.. Using a method that permits simultaneous analysis of thousands of genes at the same time, the researchers found a huge overlap in the genes whose activity were changed by... (MSNBC -- Health)
Study boosts wine chemical hopes Jun 4, 2008
"There must be a few master biochemical pathways activated in response to caloric restriction, which in turn activate many other pathways - and resveratrol seems to activate some of those master pathways as well.". Hard to take. (BBC News -- Health)
New hints seen that red wine may slow aging Jun 4, 2008
The reflex can be prompted by a faminelike diet, known as caloric restriction, which extends the life of laboratory rodents by up to 30 percent but is far too hard for most people to keep to and in any case has not been proven to work in humans ... The Wisconsin team first defined the pattern of gene activity established in mice on caloric restriction, and then showed that very low doses of resveratrol produced just the same pattern. (International Herald Tribune)
Low doses of resveratrol keep you young at heart Jun 4, 2008
Beyond the good heart news, the study suggests that caloric restriction and resveratrol may both be part of master genetic pathways related to aging. "There must be a few master biochemical pathways activated in response to caloric restriction, which in turn activate many other pathways," explains Tomas Prolla, a UW-Madison professor of genetics and senior author of the report. (USA Today -- Tech)
'PLoS ONE' STUDY: A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice Jun 4, 2008
PLoS ONE: A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice ... A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice ... Citation: Barger JL, Kayo T, Vann JM, Arias EB, Wang J, et al. (2008) A Low Dose of Dietary Resveratrol Partially Mimics Caloric Restriction and Retards Aging Parameters in Mice. (USA Today -- Tech)
Low-carb Diets Work for Diabetics May 29, 2008
"Advice to obese patients with type 2 diabetes to follow a 20% carbohydrate diet with some caloric restriction has a lasting effect on bodyweight and glycemic control," the investigators conclude. SOURCE: Nutrition and Metabolism, May 2008. (Newsmax)
Local speaker reveals real road to ‘Fountain of Youth’ (1) May 26, 2008
Simple caloric restriction, he said, is critical, the easiest to understand, he put it, and yet the most difficult to follow. Start with eliminating pasta, potatoes, and bread, he began, and change how we eat, what we eat, how quickly, how we prepare it, he continued. (Green Valley News & Sun, AZ)
Low-Calorie Mice Outlive Exercisers May 15, 2008
Instead, researchers said, they found that that caloric restriction creates beneficial changes in hormone levels, which exercise does not. The researchers concluded that these metabolic changes play a role in extending life. (Click2Houston, TX)
Less Food Beats Exercise to Increase Longevity May 14, 2008
However, at least two studies which examined people who engage in high-volume exercise versus people who restricted their calorie intake, had a similar outcome: caloric restriction has physiological benefits that exercise alone does not ... Taken together, these findings indicate that caloric restriction protects against disease better than exercise does, and has the added benefit of extending the life span of some rats ... One theory is that exercise places stress on the body, which can result... (Newsmax)
Got Sugar? Skeletal Muscle Development Responds To Nutrient Availability May 13, 2008
The study adds a new twist to ongoing research into the effects of caloric restriction on physiology and aging and may lead to new therapeutic avenues for muscle wasting. See also. (Science Daily)
Longevity quest moves slowly from lab to life Apr 23, 2008
Eating way, way lessKnown as caloric restriction, or CR, the practice of reducing food intake by at least 30 percent and as much as 70 percent has been regarded for decades as the gold standard for boosting longevity. Its the single therapy reliably shown to extend lifespan and reduce disease in yeast, worms, flies and rats and to promise the same for primates and, perhaps, people. (MSNBC -- Terrorism)
Calorie Restriction Limits -- And Obesity Fuels -- Development Of Epithelial Cancers Apr 16, 2008
6, 2007) Caloric restriction in non-obese people translates into less oxidative damage in muscle cells, according to a new study by Anthony Civitarese, Eric Ravussin and colleagues (Pennington Biomedical. . (Science Daily)
Fertility drug shortage partly due to unapproved cosmetic use Mar 19, 2008
Interestingly though, the FDA pointed out to us Ferring s own Web site and package insert saying, there is no substantial evidence that it increases weight loss beyond that resulting from caloric restriction, that it causes a more attractive or normal distribution of fat. A Schering Plough spokeswoman said the shortage comes from increased assisted reproductive procedures. (KHOU.com, TX)
Cut calories, live longer Mar 15, 2008
Enter caloric restriction (CR), an idea that has been around since the 1930s when scientists discovered that feeding mice about half of their calorie needs lived longer than the mice given standard lab chow ... Perusing the Website the "Caloric Restriction Society" () it is clear that some people are performing their own experiments by voluntarily restricting calories by 30 to 40 percent of what is recommended by the Dietary Reference Intakes for healthy adults ... Some people who follow CR... (Atlanta Journal-Constitution)
Exercise and caloric restriction may be treatment method for metabolic syndrome Feb 28, 2008
Published in the March/April issue of AJLM, the article, written by Peter M. Janiszewski, MSc, Travis J. Saunders BSc, and Robert Ross, PhD, at Queens University, reviews existing evidence that exercise and caloric restriction can be a valid treatment strategy for metabolic syndrome. The article is representative of the type of research published in AJLM, providing health professionals with real strategies for incorporating lifestyle modification into clinical medicine. (EurekAlert!)
Where people live the longest Feb 20, 2008
Scientists call it caloric restriction, but don't entirely understand why it works. They think it sends a signal to the body that there is going to be a impending famine, sending it into a protective, self-preservation mode. (BBC News -- UK)
Born to Be Obese? Feb 7, 2008
"Having said that, reasonable, healthy caloric restriction and a safe and sustainable program of physical activity can help limit weight gain and often bring about some degree of weight loss. In addition, healthy eating and regular exercise can reduce the complications of obesity such as type 2 diabetes and cardiovascular disease.". At the same time, she added, not everyone can wear a size 4. (MEDLINEplus)
The Dietitian Magician: Effects of whole foods on aging Jan 30, 2008
" He went on to explain that an early sign of memory loss is the inability to remember names. I am doomed. How to jump-start your brain According to Joseph, there are three things you can do to help your brain make more neurons. * Exercise. Research demonstrates those who exercise have bigger brains. * Caloric Restriction. Evidence suggests that getting the nutrients in is much more important than the excess calories. Restriction of caloric intake lowers levels of oxidative damage, slowing... (Ames Daily Tribune, IA)
Eat less or exercise more? Either way leads to more youthful hearts Jan 11, 2008
"So the arteries and heart muscle stiffen, and the heart doesn't relax as well after contracting. Similar studies that we've conducted with members of the Caloric Restriction with Optimal Nutrition Society (CRONies) show they have heart function resembling much younger people." CRONies voluntarily consume about 25 percent fewer calories than the average American while still maintaining good nutrition ... Riordan MM, Weiss EP, Meyer TE, Ehsani AA, Racette SB, Villareal DT, Fontana L, Holloszy JO,... (EurekAlert!)
Aging gracefully requires taking out the trash Dec 15, 2007
Insulin signaling and caloric restriction are two major determinants of longevity and they also impact the activity level of autophagy. Therefore, regulating autophagy, the pathway that directly does the cleanup work, may be the key factor in controlling the aging process, the researchers say. (EurekAlert!)
How to avoid cancer Dec 13, 2007
So we need to shed those kilos with exercise and caloric restriction a weight loss diet. Secondly, exercise. (ABC Online)
Fighting Diseases Of Aging By Wasting Energy, Rather Than Dieting -- Works For Mice Dec 7, 2007
"Calorie restriction prolongs lifespan in animals, and Dr. Holloszy has elegantly begun to translate caloric restriction studies to humans.". In landmark studies in the 1980s, Holloszy's team also had shown that rodents getting a great deal of exercise tended to live longer, but unlike calorie-restricted rodents, their maximum lifespan did not change. (Science Daily)
Mice Lacking Enzyme Renin Stay Lean On High-fat Diet, With Little Exercise Dec 7, 2007
25, 2002) A new National Cancer Institute study reported April 23 by Dr. Volker Mai at the Experimental Biology 2002 meeting in New Orleans shows that even moderate caloric restriction reduced by 60 percent. (Aug. (Science Daily)
Worms live longer under antidepressants, scientists find Nov 22, 2007
What's more, the drugs appear to extend their lifespan using the same mechanisms by which caloric restriction extends lifespan in a number of organisms ... While the creature using mianserin eats normally, Buck thinks its body may perceive it is starving, thus perhaps jolting the life-extending outcome of caloric restriction into action. (CBC.ca)
Antidepressant Found To Extend Worm Lifespan Nov 22, 2007
Intriguingly, the drug may act by mimicking the effects of caloric restriction, which has been shown to retard the effects of aging in a variety of animals ranging from worms and flies to mammals. "Our studies indicate that lifespan extension by mianserin involves mechanisms associated with lifespan extension by dietary restriction," said Buck, a member of the Basic Sciences Division of the Fred Hutchinson Cancer Research Center in Seattle. (Science Daily)
Severely Restricted Diet Linked To Physical Fitness Into Old Age Oct 27, 2007
The study, using a rat model of life-time caloric restriction, showed that the diet reduces the amount of visceral fat, which expresses inflammatory factors that in humans cause chronic disease and a decline in physical performance and vitality across the lifespan ... "This is the first study to report that caloric restriction reduced production in visceral fat of the inflammatory cytokine IL-6 and enhanced performance on overall physical function assessments," said Tongjian You, Ph. (Science Daily)
Some try calorie restriction for long life Oct 6, 2007
Sept. 21: NBC's Robert Bazell looks at a key experiment -- and talks to believers in caloric restriction. Nightly News. (MSNBC -- Terrorism)
Eat (Less) to Live (Longer) Sep 29, 2007
HEALTHY (LONG) LIVING: Scientists believe they have an idea of how caloric restriction diets lead to increaed longevity. Scientists have known for more than 70 years that the one surefire way to extend the lives of animals was to cut calories by an average of 30 to 40 percent. (Scientific American)
Eat Less To Live Longer: Calorie Restriction Linked To Long Healthy Lives Sep 27, 2007
For nearly 70 years scientists have known that caloric restriction prolongs life ... When cells experience certain kinds of stress, such as caloric restriction, these genes rev up and help protect cells from diseases of aging ... When cells undergo caloric restriction, signals sent in through the membrane activate a gene called NAMPT. As levels of NAMPT ramp up, a small molecule called NAD begins to amass in the mitochondria. (Science Daily)
Researchers Pinpoint Link Between Caloric Restriction and Longevity Sep 22, 2007
This suggests that if SIRT3 and SIRT4 could be chemically activated, it might be possible to achieve the benefits of caloric restriction without the diet. That could slow the progress of diseases based on cell death, such as Alzheimer's, cancer and diabetes, he said, and possibly extend life span as a result. (MEDLINEplus)
Mitochondria regulate cell stress Sep 21, 2007
The study is the first to link mitochondrial sirtuins to stress resistance in the cell, and the first to link sirtuins other than SIRT1 to caloric restriction, Sinclair said. He added that molecules in the mitochondrial NAD+ pathway may represent new drug targets to treat diseases of aging. (The Scientist)
Key to longer life (in flies) lies in just 14 brain cells Sep 21, 2007
But how, exactly, does p53 do its work in the brain" To find out, Bauer spent a year conducting painstaking experiments. Hed take a batch of young flies, each genetically altered to reduce p53 activity in a small portion of their nervous systems, and watch the flies age. Time and again, the flies lived for about two months the average lifespan for these insects. But when Bauer manipulated a cluster of 14 insulin-producing cells in their brains, the flies lived about 15 to 20 percent longer.... (EurekAlert!)
Science Matters, Tom Siegfried: With eating, sleeping and aging, timing is everything Aug 31, 2007
"Several theories explain how caloric restriction modulates aging and longevity, but the exact mechanisms are still unknown," write Froy, of the Hebrew University of Jerusalem, and Miskin, of the Weizmann Institute of Science in Rehovot, Israel. Perhaps, Froy and Miskin suggest, the life-extending effect of fewer calories is related to the biological clock. (Why Files)
Dietary Restriction Cleans Cells Aug 25, 2007
"Caloric restriction is a way to extend life in animals. If you give them less food, the stress of this healthy habit actually makes them live longer," said Christiaan Leeuwenburgh, Ph ... "What if we bypass the caloric restriction and find a way of increasing autophagy"" asked Dunn. "That is, instead of starving yourself you can find another way of enhancing autophagy that will allow the enhanced removal of various damaged organelles that accumulate in aged cells. (Science Daily)
UF scientists reveal how dietary restriction cleans cells Aug 24, 2007
Caloric restriction is a way to extend life in animals ... What if we bypass the caloric restriction and find a way of increasing autophagy" asked Dunn. That is, instead of starving yourself you can find another way of enhancing autophagy that will allow the enhanced removal of various damaged organelles that accumulate in aged cells. Ulf Brunk, M.D., Ph.D., a professor emeritus of experimental pathology at Linkping University in Sweden, said the study builds on past research showing that... (EurekAlert!)
Abnormal fat metabolism underlies heart problems in diabetic patients Aug 11, 2007
Mancuso DJ, Han X, Jenkins CM, Lehman JJ, Sambandam N, Sims HF, Yang J, Yan W, Yang K, Green K, Abendschein DR, Saffitz JE, Gross RW. Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2. Journal of Biological Chemistry 2007 Mar;282(12):9216-9227. (EurekAlert!)
Genaera Corporation to Present at ThinkEquity Partners LLC Second ... Jul 31, 2007
Trodusquemine has produced consistent, sustainable weight loss in a variety of animal models and appears to overcome metabolic readjustment, which often limits sustained weight loss during caloric restriction. In addition, trodusquemine has shown the ability to address co-morbidities associated with obesity such as abnormal glucose metabolism and cholesterol elevation. (CNNMoney.com)
Gene deficiency is a protective barrier to obesity Jun 27, 2007
Research in animal models has shown that caloric restriction can lower cholesterol and blood pressure -- often considered the biomarkers of aging. In addition, published research in animal models shows that caloric restriction, defined as consuming 30 percent to 40 percent less than your average daily intake, can turn on the SIRT1 gene, one of a family of seven genes linked to longevity. (EurekAlert!)
Weight Loss: Myth Vs. Reality Jun 5, 2007
Three weeks of caloric restriction alters protein metabolism in normal-weight, young men. American Journal of physiology, Endocrinology and metabolism; 289(3): E 446-55. (CBS New York, NY)
Calcium Plus Vitamin D Supplements May Help Prevent Weight Gain In Postmenopausal Women May 16, 2007
"Prevention of weight gain is an important public health goal, and caloric restriction and daily physical activity should still be considered the basic tenets of weight management," the authors conclude. "Further research should be undertaken to address the effect of calcium supplementation combined with caloric restriction and physical activity on weight gain prevention.". (Science Daily)
Thin people might be fat on the inside May 11, 2007
Even if you dont see it on your bathroom scale, caloric restriction and physical exercise have an aggressive effect on visceral fat, said Dr. Bob Ross, an obesity expert at Queens University in Canada. Click for related content. (MSNBC -- Health)
Clue in restricted diet-life span link May 8, 2007
A team of researchers at the Salk Institute in San Diego has identified a gene in roundworms that appears crucial for producing the life-extending effects of caloric restriction. Although other genes have been found to play a role, the new gene, known as PHA-4, appears to be the first that is necessary to achieve the effects. (Newsday -- Health)
* Gene identified in roundworms may promote longevity May 4, 2007
The stakes are high: a drug that mimicked the effects of caloric restriction in people could lead to significant increases in lifespan. But much work remains to be done in roundworms and mice to define the genetic pathway and its possible side effects in people, like reduced fertility. (Taipei Times, Taiwan -- World)
Why Calorie Restriction Might Prolong Life May 3, 2007
"This suggests that there could be specific genetic pathways that modulate organisms' response to caloric restriction. If there are, we can now screen to find drugs to modulate," said Heidi A. Tissenbaum, an associate professor in the Program in Gene Function and Expression at the University of Massachusetts Medical School ... Pha-4 has nothing to do with the insulin/IGF signaling pathway, something the researchers stressed, but it is critical for longevity related to caloric restriction ... One... (Forbes)
Herbal remedy fights recurring urinary tract infections Apr 10, 2007
Nutrition The first phase of a caloric restriction study in human subjects at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University found evidence suggesting that calorie-restricted diets differing substantially in glycemic load can result in comparable long-term weight loss. Apr 9, 2007 - 7:00:27 PM. (Food Consumer)
Study examines calorie restriction and glycemic load Apr 9, 2007
Boston The first phase of a caloric restriction study in human subjects at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University found evidence suggesting that calorie-restricted diets differing substantially in glycemic load can result in comparable long-term weight loss. The study, part of the multi-center Comprehensive Assessment of Long-term Effects of Restricting Intake of Energy (CALERIE) trial, funded by the National... (EurekAlert!)
Eating meat enhanced with isotopes to a longer life Mar 27, 2007
Previous successes in extending lifespan have involved withdrawing food to the point of near starvation, a process called caloric restriction. (Last updated on Monday, March 26, 2007, and first posted on Sunday, March 25, 2007). (SpiritIndia)
Meat and two neutrons -- the key to a longer life Mar 26, 2007
Previous successes in extending lifespan have involved withdrawing food to the point of near starvation, a process called caloric restriction. . (EurekAlert!)
How Eating Less Might Make You Live Longer Mar 7, 2007
Caloric Restriction in non-obese people translates into less oxidative damage in muscle cells, according to a new study by Anthony Civitarese, Eric Ravussin, and colleagues (Pennington Biomedical Research Center) ... But how might caloric restriction slow aging ... One theory for h ow caloric restriction slows aging is that it lowers free-radical production by inducing the formation of efficient mitochondria. (Science Daily)
Cut your calorie intake to live longer Mar 7, 2007
One theory for how caloric restriction slows aging is that it lowers free-radical production by inducing the formation of efficient mitochondria ... They were divided in three groups C one receiving 100 per cent of their energy requirements, caloric restriction group (CR) with 25 per cent cut in calorie intake, and caloric restriction plus exercise (CREX) group with 12 ... They suggest that even short-term caloric restriction can produce beneficial physiological changes leading to improved... (China Daily)
Researchers Find Link Between Food Odors And Lifespan In Fruit Flies Feb 21, 2007
Van Voorhies said metabolic studies of the fruit flies showed that longer lifespans in those subjected to caloric restriction were not simply a result of slower metabolism ... "It will live longer but everything is going slower in the animal, so you haven't fundamentally altered the way it has aged. So we wanted to make sure the effect of caloric restriction wasn't just slowing the animals down, and we found that it wasn't. You can have a high metabolic rate and be long-lived, and that's an... (Science Daily)
Love that food smell? Beware Feb 13, 2007
Scott Pletcher, a geneticist at the Huffington Center on Aging at Baylor College of Medicine in Houston, knew that the mere scent of food could block some of the life-extending effects of caloric restriction in tiny, soil-dwelling worms. So he and his colleagues conducted similar tests in flies. (Mail Tribune, OR)
