Final 12 Month Clinical Data from 5,000 Patients in Worldwide e-HEALING Clinical Study Show Good Safety and Efficacy with Real World Use of OrbusNeich's Genous(TM) Bio-engineered R stent(TM) Sep 23, 2009
7 percent, a subacute thrombosis (SAT) rate of 0. 5 percent and a late stent thrombosis (LST) of 0 ... The combined SAT and late thrombosis rate of 0. (PR Newswire)
OrbusNeich's Genous(TM) Bio-Engineered R Stent(TM) is Safe in a Broad Population of Patients with Primary PCI for STEMI Sep 23, 2009
7 percent and the rate of subacute thrombosis was 1 ... "STEMI often presents challenges to interventional cardiologists as the condition can result in delayed stent endothelialization and lead to thrombosis with drug eluting stents," said Dambrink ... "The interim data further support the safety profile of the Genous Bio-engineered R stent in this patient population as we confirm the low subacute stent thrombosis rate seen in several large trials for the Genous Bio-engineered R stent.". (PR Newswire)
One-year results from Horizons-AMI trial reported at TCT 2009 Sep 22, 2009
9%) and non-significant trends toward less stent thrombosis (2. 2% vs. 4. (EurekAlert!)
Boston Scientific PROMUS(R) and First-Generation TAXUS(R) Express(R) Stents Continue Excellent Performance in SPIRIT III Trial Sep 22, 2009
68) and low and equivalent rates of stent thrombosis using the ARC (Academic Research Consortium) definite/probable definition (1. 2% and 1. (PR Newswire)
› Stroke: reduce your risk Sep 22, 2009
One is caused by haemorrhage (flooding the brain with blood) while the other is caused by a cutting off in the supply of blood to the brain as a result of a thrombosis or embolism. The disabilities caused by a stroke depend upon which areas of the brain have been affected. (iAfrica.com)
Few complications 1 year after aortic valve implantation Sep 22, 2009
Non-structural valve deterioration or valve thrombosis did not occur. Mean aortic gradient decreased to 11 4 mm Hg (valve size 26) and 12 4 mm Hg (valve size 29), and valve orifice area increased to 1. (EurekAlert!)
Image-guided treatment for deep venous thrombosis could improve patients' long-term outcomes Sep 21, 2009
Deep Venous Thrombosis (DVT) is a serious condition that involves the formation of a blood clot inside of a deep vein usually in the legs. A patient with DVT is typically treated with anticoagulants (blood thinners) however researchers have found that image-guided interventional radiology procedures may play a more central role in the long-term treatment of DVT, according to a study published in the October issue of the American Journal of Roentgenology (AJR). (EurekAlert!)
deCODE Discovers Four New Risk Factors for Prostate Cancer Sep 21, 2009
Through its chemistry and biology units deCODE has also developed a therapeutic product portfolio, which includes DG041, an antiplatelet compound being developed for the prevention of arterial thrombosis; DG051, a compound targeting the leukotriene pathway for the prevention of heart attack; and DG071 and a platform for other PDE4 modulators with therapeutic applications in Alzheimer's disease and other conditions. The company intends to partner or directly outlicense these programs. (PR Newswire)
Free DVT Screenings Can Help Save L... Sep 19, 2009
In addition, the Coalition to Prevent Deep Vein Thrombosis offers a brief risk-assessment quiz, which is available on the. Prolonged Bed Rest, Serious Injury and Surgery are Major DVT Risk Factors. (Suite101.com)
Invention Can Turn Red Wine By-products Into Yoghurt, Chocolates, Creams And More Sep 19, 2009
He proposed his company develop a method to turn the by-products into a powder preserving as many of the natural, healthy properties of wine as possible - the proteins, B vitamins, minerals and polyphenols, which are thought to prevent heart or circulation diseases, inflammation and thrombosis. As a relatively small company, Spectral decided to partner with the larger Technologie-Transfer-Zentrum (TTZ), German specialists in product development, and the pair successfully applied to carry out... (Science Daily)
Regado Biosciences Announces Allowance in Europe of a Fundamental Patent Broadly Covering Oligonucleotide Modulators to Blood Coagulation Factor Aptamers Sep 18, 2009
REG1 is intended for application in arterial thrombosis applications, initially in Acute Coronary Syndrome patients undergoing Percutaneous Coronary Intervention ... REG2 is intended for use in venous thrombosis indications. (PR Newswire)
ahrq Announces New Video to Help Patients Use Blood Thinner Pills Safely and Effectively Sep 15, 2009
Nearly 2 million Americans receive prescriptions for blood thinners each year to reduce their risk of forming dangerous blood clots that can lead to serious conditions such as deep vein thrombosis -- clots that form in the deep veins of the legs or groin -- or pulmonary embolism -- clots that travel to the lungs and can be fatal. Patients who have had certain kinds of stroke or who have a type of irregular heartbeat known as atrial fibrillation are often prescribed blood thinners, as are... (PR Newswire)
Rapid-response Technology from NeuroInterventions, Inc. Aims to Quickly Restore Brain's Blood Flow After a Stroke Sep 14, 2009
Founded in 2007 and based in Pittsburgh, NeuroInterventions is prototyping a family of patent-pending catheters for addressing conditions that include deep vein thrombosis, carotid stenting, traumatic brain injury, and stroke. The technology also facilitates localized drug and stem cell delivery. (PR Newswire)
Painful reminders Sep 13, 2009
Ten years ago, following a thrombosis, Trudy had to have most of her small bowel removed. She now has short bowel syndrome which leads to changes in metabolism making her form kidney stones very frequently, due to poor absorption of calcium and bile. (BBC News -- UK)
OrbusNeich's Genous(TM) Bio-engineered R stent(TM) is Feasible in Patients Requiring Undeferrable Non-Cardiac Surgery, International Journal of Cardiology Publication Reports Sep 12, 2009
The technology consists of an antibody surface coating that attracts EPCs circulating in the blood to the device to form an endothelial layer that provides protection against thrombosis and modulates restenosis. OrbusNeich's Genous Bio-engineered R stent has been commercially available in over 60 countries since 2005. (PR Newswire)
Ticagrelor — Is There Need for a New Player in the Antiplatelet-Therapy Field? Sep 10, 2009
3 Patients with a poor response to clopidogrel have an increased risk of coronary thrombosis. 4 The. (New England Journal of Medicine)
Flintoff off to Dubai for rehab Sep 9, 2009
" Flintoff, will work with former England physio Dave Roberts, a close friend, as he bids to regain full fitness. He had a fresh injury scare when suffering a deep vein thrombosis as a side-effect of surgery but Flintoff has since been given the all clear to fly. "I had a stiff calf and it got progressively worse," said Flintoff, who is on a course of anti-coagulants and will be on crutches for a minimum of one more month. "I spent the night in hospital, but it's more of a complication than... (Sydney Morning Herald -- Sport)
How greens may protect the heart Sep 5, 2009
Details appear in Arteriosclerosis Thrombosis and Vascular Biology. BRASSICAS Broccoli Cabbage Kale Brussels sprouts Cauliflower Bok choy Rocket. (BBC News -- Health)
Broccoli, cabbage are good for heart Sep 5, 2009
ANI5 September 2009, 12:22pm IST. Heres why broccoli, cabbage and cauliflower are good for the heart a chemical found in these vegetables can boost a natural defence mechanism to protect arteries from disease. (India Times, India)
Protein Modifier SUMO Helps Set Apart Females And Males Sep 4, 2009
(July 14, 2008) Being male increases your risk of diseases caused by the inappropriate formation of a blood clot (a process known as thrombosis), such as heart attack and stroke, but the reasons for this are not. (May 12, 2009) Women have a more powerful immune system than men, according to a new study. (Science Daily)
'S' Stands For Surprise: Anticoagulant Plays Unexpected Role In Maintaining Circulatory Integrity Sep 3, 2009
The resulting deficiencies predispose carriers to deep venous thrombosis, strokes at an early age, recurrent miscarriages, and pre-eclampsia, and are associated with several autoimmune diseases, most prominently systemic lupus erythematosus ... In patients who are born with two abnormal copies of the protein S gene, a severe form of thrombosis called purpura fulminans can result. (Science Daily)
Video: RE-LY Trial Met Primary Outcome for Reducing Incidence of Stroke or Systemic Embolism in Non-valvular Atrial Fibrillation Patients Aug 31, 2009
gov. "Twice-Daily Oral Direct Thrombin Inhibitor Dabigatran Etexilate in the Long-Term Prevention of Recurrent Symptomatic Proximal Venous Thromboembolism in Patients With Symptomatic Deep-Vein Thrombosis or Pulmonary Embolism." Available at ... (22) Eriksson BI, et al. "Oral Dabigatran Etexilate vs. Subcutaneous Enoxaparin for the Prevention of Venous Thromboembolism After Total Knee Replacement: the RE-MODEL Randomized Trial." Journal of Thrombosis and Haemostasis. (PR Newswire)
Abbott Launches Next-Generation XIENCE PRIME(TM) Drug Eluting Stent in International Markets Aug 31, 2009
7 percent rate of definite/probable stent thrombosis and a 5. 1 percent rate of MACE at one year, in a diverse, "real world" population of patients and lesion types. (PR Newswire)
Study Shows Otamixaban Substantially Reduced Complications of Invasive Management of Acute Coronary Syndromes Aug 31, 2009
Otamixaban is originating from Sanofi-aventis world-class thrombosis research portfolio and is currently in phase IIb clinical development phase. "The data show that intermediate dosages of otamixaban may offer substantial reduction in major coronary complications in patients presenting with acute coronary syndrome, with bleeding rate comparable to current therapy," said Dr Marc Sabatine, MD, MPH, an Investigator in the TIMI Study Group and a cardiologist at Brigham and Women's Hospital, Harvard... (PR Newswire)
New Large-Scale, Global Study Provides Additional Information About an Intensified Dose-Regimen of PLAVIX(R) in Acute Coronary Syndrome Patients Undergoing Angioplasty Aug 30, 2009
In addition, analysis showed an important 42% relative risk reduction in definite stent thrombosis (1. 2% vs 0. (PR Newswire)
Video: Phase III Head to Head Trial Showed Ticagrelor Reduced Cardiovascular Death and Heart Attacks Over Clopidogrel in Acute Coronary Syndromes Patients Aug 30, 2009
Among patients who received a stent during the study, a 33% reduction in risk of definite stent thrombosis was achieved with ticagrelor. "The goal of new antiplatelet therapies is to improve the efficacy for patients without increasing the associated risks of treatment such as bleeding. Ticagrelor achieved a significant reduction in CV mortality in ACS patients versus clopidogrel and importantly without an increase in major bleeding," commented Professor Lars Wallentin, co-chair of the PLATO... (PR Newswire)
Rigels R788 CV adverse event profile draws comparisons to Mercks withdrawn Vioxx, experts say Aug 30, 2009
It was evident that Vioxxs mechanism of action clearly promoted thrombosis and heart attacks, but it is unclear if R788 actually increases more serious adverse events at this point, Karsh noted. An increased risk of heart attacks was not apparent in data released in July from the six-month Taski2 trial. (FT.com -- Markets)
Keller Rohrback L.L.P. Announces Investigation of Harmful Side Effects Associated With Yaz and Yasmin Birth Control Pills Aug 29, 2009
These birth control pills have been linked to serious and dangerous side-effects, including, but not limited to the following: Pulmonary embolism; Blood clot; Gallbladder disease; Deep vein thrombosis; and Heart attack. If you or someone you know has been seriously harmed as a result of taking Yaz or Yasmin, or you would like additional information regarding this investigation, please contact attorney Mike Woerner (800) 776-6044 or via email at. (Primezone Releases)
Gene Variant Linked To Effectiveness Of Popular Anti-clotting Medication Plavix Aug 27, 2009
The researchers collaborated with investigators at the Sinai Center for Thrombosis Research in Baltimore, confirming their findings by studying a group of 227 people who received Plavix after having stents implanted to open blocked coronary arteries at Sinai Hospital. Paul A. Gurbel, M.D., senior author of the study and director of the Sinai Center for Thrombosis Research, says that "patients with the CYP2C19 variant had a diminished platelet response to clopidrogrel treatment and poorer... (Science Daily)
UK HEALTH SYSTEM: 'Cruel and neglectful' care of one million patients exposed... Aug 27, 2009
I have never forgotten the wonderful care my other received in the high dependancy unit, and the appaling care in the ordinary ward afterwards - she was left slumped in a chair all day and developed a thrombosis in her leg - I went twice every day to clean the area round her bed and walk her round the ward - and I got her out of there as fast as I could. Nurses, they were slumped too - at the nursing station filling in forms and barely raised their heads when I went in. (The Drudge Report)
Women more likely to die after heart attack Aug 26, 2009
"Our research concludes that there is a difference in mortality between men and women depending on the type of ACS they suffer," said lead study author, Dr Jeffrey Berger, MS, Director of Cardiovascular Thrombosis, Cardiovascular Clinical Research Center, The Leon H Charney Division of Cardiology at NYU School of Medicine. "Among STEMI or more severe heart attacks - 30 day mortality was significantly higher among women than men. For NSTEMI or less severe heart attacks and unstable angina... (India Times, India)
Cardiovascular Diseases: Researchers Have Found A Way To Treat Ischemic Pathologies Aug 19, 2009
These obstructions occur, for example, in the event of thrombosis in a limb, myocardial infarction or a stroke. In this sense, it is important to highlight the fact that cardiovascular diseases are the principal cause of death throughout the world (in the European Union, they account for 40% of all deaths, a figure equivalent to 2 million deaths per year). (Science Daily)
Some Birth Control Pills Safer Than Others Aug 15, 2009
Scientists have long known that oral contraceptives, which contain the female hormones estrogen and progestogen, increase the likelihood of deep vein thrombosis of the leg and pulmonary embolism, but new studies in Denmark and the Netherlands determined that some pills are safer than others. Neither study received funding from any companies that make oral contraceptives. (MEDLINEplus)
New No-needle Approach To Prevent Blood Clots Aug 14, 2009
Blood clots, known as deep-vein thrombosis (DVT), affect the large veins in the lower leg and thigh ... On average, 1 percent to 3 percent of people undergoing total joint replacement will end up with a symptomatic deep-vein thrombosis (blood clot in the legs) or a pulmonary embolism (a blood clot in the lungs) ... 30, 2008) The use of ultrasound waves for deep vein thrombosis may help dissolve blood clots in less time than using clot-busting drugs alone, according to. (Science Daily)
Many women 'not on safest pill' Aug 14, 2009
It has been known for a long time that the combined pill, which contains both oestrogen and progestogen, was associated with an increased risk of venous thrombosis - a blood clot that forms in a vein ... In the first study done by Dutch researchers - looking at data from 1,524 women who had developed venous thrombosis - they found that overall taking the pill was associated with a five-fold increased risk of a clot ... Women taking pills containing a progestogen called levonorgestrel (for... (BBC News -- Health)
Protein Unfolding Is Key For Understanding Blood Clot Mechanics Aug 8, 2009
7, 2009) Fibrin, the chief ingredient of blood clots, is a remarkably versatile polymer. On one hand, it forms a network of fibers -- a blood clot -- that stems the loss of blood at an injury site while remaining pliable and flexible. (Science Daily)
Student, 18, Suffers Severe Blood Clot Sitting for Exams Aug 4, 2009
Thompson developed deep vein thrombosis, a blood clot in her leg vein, and her right leg was so swollen by the time she took her English literature exam, she couldn t even walk ... My advice to other (students) is to make sure they get up and walk around every hour or two, said Dr. John Scurr, a consultant surgeon at the Lister Hospital in London, who is also an expert on deep vein thrombosis. (Fox News)
Risk Of Developing Deep Vein Thrombosis During A Flight Is Often Overestimated, According to Some Experts Jul 25, 2009
ScienceDaily (July 24, 2009) The risk of developing deep vein thrombosis during a long flight is often overestimated according to researchers ... When people wear a cast or splint after a sports accident, on the other hand, many are not aware that they have an increased risk of deep vein thrombosis in their leg and pelvic area ... As a result, blood may clump together, forming a blood clot which can lead to deep vein thrombosis. (Science Daily)
Stroke: One Disease, Two Effects Jul 25, 2009
(July 14, 2008) Being male increases your risk of diseases caused by the inappropriate formation of a blood clot (a process known as thrombosis), such as heart attack and stroke, but the reasons for this are not. (May 19, 2005) Children of both genders are frequently victims of sexual abuse, and the long-term consequences are nearly identical in men and women, according to a broad-based new report in the June 2005 issue of. (Science Daily)
New Drug May Reduce Heart Attack Damage Jul 25, 2009
ScienceDaily (July 24, 2009) A new drug that targets a master disease-causing gene can dramatically reduce heart muscle damage after a heart attack and may lead to significantly improved patient outcomes, UNSW researchers have shown. The drug, known as Dz13, specifically targets and neutralises the gene responsible for inflammation and muscle death in the aftermath of a heart attack, preclinical trials have found. (Science Daily)
Clotting In Veins Close To Skin May Be Associated With More Dangerous Deep-vein Blood Clots Jul 22, 2009
ScienceDaily (July 21, 2009) About one-fourth of patients with superficial vein thrombosis clotting in blood vessels close to the skin also may have the life-threatening condition deep vein thrombosis, according to a report in the July issue of Archives of Dermatology, one of the JAMA/Archives journals ... "Superficial vein thrombosis is a common disease that most often affects the veins of the leg but can also be found in other locations," the authors write as background information in the... (Science Daily)
Superficial blood clots may cause deep vein thrombosis: Study Jul 22, 2009
BEIJING, July 21 (Xinhuanet)- About one-fourth of patients with superficial blood clots may be at greater risk for life-threatening deep vein thrombosis, according to a new study. Austrian researchers said Monday, "varicose veins, thrombophilia (a disorder in which the blood clots too easily), use of oral contraceptives, trauma, malignancy or a period of immobility can cause blood clots near the surface of the legs. "In the past, not much interest has been focused on superficial vein thrombosis... (Xinhuanet, China)
Vein Condition May Mask Serious Clot Disorder Jul 22, 2009
Superficial vein thrombosis linked to deep vein thrombosis, study says ... MONDAY, July 20 (HealthDay News) -- A supposedly harmless condition -- superficial vein thrombosis, or varicose veins that have become swollen and painful -- may herald the presence of a more dangerous problem ... One-quarter of patients with superficial vein thrombosis (SVT) in an Austrian study actually had deep vein thrombosis (DVT), a potentially life-threatening condition. (MEDLINEplus)
Summary for Patients Jul 21, 2009
Predicting Deep Venous Thrombosis in Pregnancy: Out in "LEFt" Field ... Predicting Deep Venous Thrombosis in Pregnancy ... The summary below is from the full report titled "Predicting Deep Venous Thrombosis in Pregnancy: Out in "LEFt" Field?" It is in the 21 July 2009 issue of Annals of Internal Medicine (volume 151, pages 85-92). (Annals of Internal Medicine)
Daiichi Sankyo and Lilly Receive U.S. FDA Approval for Effient(TM) Jul 11, 2009
PARSIPPANY, N.J. and INDIANAPOLIS, July 10 /PRNewswire-FirstCall/ -- Daiichi Sankyo, Inc. and Eli Lilly and Company (NYSE: ) today announced that the U.S. Food and Drug Administration (FDA) approved Effient(TM) (prasugrel) tablets for the reduction of thrombotic cardiovascular events (including stent thrombosis) in patients with acute coronary syndromes who are managed with an artery-opening procedure known as percutaneous coronary intervention (PCI) ... Taking Effient with aspirin after PCI has... (PR Newswire)
Burg Simpson Files Yasmin/Yaz Lawsuits Jul 11, 2009
The four women who filed suit suffered either deep vein thrombosis, pulmonary embolism, and/or stroke while taking these products. In addition, both Yasmin and Yaz have been associated with heart attacks and even death in young women. (PR Newswire)
Health precautions before you fly Jul 9, 2009
Deep vein thrombosis (DVT) refers to a clot (thrombus) that is formed in the larger veins of the lower leg or the thighs because of prolonged sitting in a particular position. The clot can be fatal if it dislodges from its original position and reaches the brain, lungs and heart, causing severe damage. (India Times, India)
Click to read: Traveling Increases Risk of Blood Clots Jul 9, 2009
Dr. Jennifer Ashton spoke to Harry Smith about the dangers of deep vein thrombosis for frequent travelers ... Blood clots, known as deep vein thrombosis (DVT) or venous thromboembolism (VTE), form most often in the leg, Ashton explained. (CBS News -- Early Show)
Woman Struggles With Massive 200-Lb. Legs Jul 7, 2009
It could ve been DVT (Deep Vein Thrombosis), or it could ve been some virus that caused this, she said. That was the first time that anything particularly major had happened to my health. (Fox News)
Clot risk jumps on long flights Jul 7, 2009
The clotting is also known as deep vein thrombosis. Symptoms include swelling, pain and redness in the leg. (USA Today -- Travel)
ThromboGenics and BioInvent Start Recruitment of Second 100 Patient Cohort in Phase II DVT Prophylaxis Study With TB-402 Jul 3, 2009
TB-402 is a novel, long acting anticoagulant that is being developed for the prevention of deep vein thrombosis (DVT) following orthopaedic surgery ... Professor Peter Verhamme from the University of Leuven will present additional data from the earlier successful Phase I studies at the XXII Congress of the International Society on Thrombosis and Haemostasis (ISTH) on July 15, 2009 in Boston ... About Deep Vein Thrombosis (DVT). (PR Newswire)
Carbon Monoxide, Although Toxic, Prevents Clotting In Mice Jun 25, 2009
ScienceDaily (June 25, 2009) Researchers led by Drs. James F. George and Anupam Agarwal at the University of Alabama at Birmingham have found that carbon monoxide (CO) can protect against arterial clotting in mice. (Science Daily)
Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation Jun 25, 2009
Common adverse effects included allergic reactions to asparaginase, osteonecrosis, thrombosis, and disseminated fungal infection. Conclusions With effective risk-adjusted chemotherapy, prophylactic cranial irradiation can be safely omitted from the treatment of childhood ALL. (ClinicalTrials. (New England Journal of Medicine)
Area hospitals see mixed grades on yearly report card Jun 24, 2009
Northern Dutchess Hospital earned spots on the 2009 Honor Roll by doing better than the state average in two areas, fewer Postoperative Respiratory Failure cases and fewer Postoperative Pulmonary Embolism (or Deep Vein Thrombosis). The rest of its ratings were at the state average, beyond those already mentioned. (Catskill Daily Mail, NY)
Tips from the American Journal of Pathology Jun 24, 2009
George, Agarwal, and colleagues conclude that HO-1/CO plays an "important role [in] protection against vascular arterial thrombosis in murine aortic allotransplantation.". Chen B, Guo L, Fan C, Bolisetty S, Joseph R, Wright MM, Agarwal A, George JF: Carbon Monoxide Rescues Heme Oxygenase-1-deficient Mice from Arterial Thrombosis in Allogeneic Aortic Transplantation. (EurekAlert!)
WNY hospitals get average grades Jun 21, 2009
Millard Fillmore Gates, St. Joseph, WCA, Kenmore Mercy and Mount St. Mary1s for postoperative pulmonary embolism or deep vein thrombosis. Millard Fillmore Gates for postoperative sepsis. (Buffalo Business First, NY)
New Anticoagulant Pill Works Well in Trial Jun 19, 2009
Dr. Richard C. Becker, director of the Cardiovascular Thrombosis Center at Duke University Medical Center, said this study is another step in the search for an anti-clotting drug to replace warfarin for many patients ... The dose-related bleeding risk supports a strategy of lower doses than would be used for other potential indications for the drug, such as atrial fibrillation and venous thrombosis, he said ... SOURCES: Jessica L. Mega, M.D., Cardiovascular Division, Brigham and Women's... (MEDLINEplus)
No Benefit in Testing for Genes Linked to Leg Clots Jun 18, 2009
Taking precautions best way to avoid deep vein thrombosis, report says ... TUESDAY, June 16 (HealthDay News) -- There's no proof that genetic testing can help prevent the potentially dangerous blood clots called deep vein thrombosis, a new U.S. government report shows ... But Agency for Healthcare Research and Quality (AHRQ) researchers reviewed available scientific literature and said there's not enough evidence to conclude that genetic testing for the two gene mutations in adults with a... (MEDLINEplus)
A Car of Ones Own, Andrew OHagan,London Review of Books Jun 17, 2009
In 2006, the movie that won Best Picture was Crash, the film by Paul Haggis about racial and social tensions in Los Angeles against the backdrop of a life-threatening bout of traffic thrombosis. Congestion, says one of Vanderbilts well-deployed experts, Alan Pisarski, is people with the economic means to act on their social and economic interests getting in the way of other people with the means to act on theirs. (Harper's Magazine)
Key to blood clotting discovered Jun 6, 2009
If blood clots too much, people can develop a potentially fatal thrombosis; too little and they can bleed to death. UK experts said the research was important and could help develop new treatments for blood disorders. (BBC News -- Health)
Opening Arteries with Drug-Coated Stents OK over 70 Jun 5, 2009
Patients older than 70 had many more risk factors -- such as high blood pressure, kidney disease, congestive heart failure and prior bypass surgery -- but their rates of heart attack, stent thrombosis and repeat treatment during follow-up were similar to those of younger patients, the study found. Patients older than 70 treated with a bare-metal stent or a paclitaxel-eluting stent had similar outcomes, but those with drug-eluting stents were 54 percent less likely to require repeat treatments,... (MEDLINEplus)
Researchers Solve 'Bloodcurdling' Mystery Jun 5, 2009
Too much hemostatic activity can lead to an excess of blood clots, resulting in a potentially deadly condition known as thrombosis. If too little hemostatic activity occurs in the body, a person may bleed to death. (Science Daily)
An Autoinflammatory Disease Due to Homozygous Deletion of the IL1RN Locus Jun 4, 2009
We describe a patient with an autoinflammatory disease in which the main clinical features are pustular rash, marked osteopenia, lytic bone lesions, respiratory insufficiency, and thrombosis. Genetic studies revealed a 175-kb homozygous deletion at chromosome 2q13, which encompasses several interleukin-1 family members, including the gene encoding the interleukin-1 receptor antagonist (IL1RN). (New England Journal of Medicine)
Cepheid Receives Health Canada License for Xpert(R) HemosIL(R) FII & FV Test Jun 3, 2009
On-Demand Test for Genetic Risk of Thrombosis Improves Time-to-Result over Current Molecular Tests SUNNYVALE, Calif ... June 3 /PRNewswire-FirstCall/ -- Cepheid (Nasdaq: CPHD) and Instrumentation Laboratory today announced that Health Canada has issued Cepheid a medical device license for its Xpert HemosIL FII st. The test detects Factor II (FII) and Factor V Leiden (FV) genetic variations associated with thrombophilia, an increased risk of blood clots (thrombosis) ... "The Xpert HemosIL FII est... (Canada Newswire)
Compression Stockings Offer Little Benefit After Stroke May 29, 2009
The researchers were checking for deep vein thrombosis (DVT), a blood clot that can break up and get carried through the bloodstream to the heart and lungs, which is a potentially life-threatening problem. DVT occurred in 10 percent of patients in the compression stockings group and in 10. (MEDLINEplus)
