Sleeping sickness fight: $15M from Gates Nov 21, 2009
Gates Foundation gives $15M to combat sleeping sickness - Puget Sound Business Journal (Seattle) ... Gates Foundation gives $15M to combat sleeping sickness ... is giving $15 million to the Drugs for Neglected Diseases initiative to treat human African trypanosomiasis, also known as sleeping sickness. (Puget Sound Business Journal, WA)
Pneumonia Drug Promising Against Form of Muscular Dystrophy Nov 14, 2009
Pentamidine is approved to treat several conditions, including a severe type of pneumonia in people with compromised immune systems, some yeast infections and sleeping sickness. "Pentamidine is an exciting lead compound because it is relatively easy to chemically modify, and hopefully one of these modified compounds could lead to a safe, long-term treatment for DM1 in the future," said Berglund. (MEDLINEplus)
Possible Help In Fight Against Muscle-wasting Disease Nov 13, 2009
Pentamidine carries approval of the U.S. Food and Drug Administration for treating a severe type of pneumonia in people with weakened immune systems, as well as leishmaniasis, sleeping sickness and some yeast infections. However, levels used successfully in the experiments would be toxic in humans, Berglund said. (Science Daily)
Computers Reveal Unexpected Drug Side Effects Nov 7, 2009
29, 2008) Around 150 thousand people per year get the parasitic disease African sleeping sickness, but the only medicines to treat it are either difficult to administer, expensive, or toxic. Now a team of. (Science Daily)
Tap wealth of local products emerging to fight 'neglected' diseases of poor: study Nov 3, 2009
"Without proper drugs, vaccines and diagnostics for sleeping sickness, intestinal parasites, elephantiasis and other tropical diseases, an enormous percentage of the world's people will remain trapped in poverty.". Innovative NTDs-related products in the South. (EurekAlert!)
African Cattle To Be Protected From Killer Disease Oct 6, 2009
5, 2009) Millions of African families could be saved from destitution thanks to a much-needed vaccine that is being mass-produced in a drive to protect cattle against a deadly parasite. East Coast fever is a tick-transmitted disease that kills one cow every 30 seconds with one million a year dying of the disease. (Science Daily)
Africa: New Treatment for Sleeping Sickness Oct 1, 2009
com: Africa: New Treatment for Sleeping Sickness (Page 1 of 1). New Treatment for Sleeping Sickness ... Nairobi Patients at an advanced stage of Human African Trypanosomiasis, or sleeping sickness, can now access more convenient, safer and cheaper treatment after the introduction of Nifurtimox-Eflornithine Combination Therapy (NECT). (allAfrica.com)
Eisai and DNDi Enter Collaboration and License Agreement to Develop New Drug for Chagas Disease Sep 30, 2009
Since 2007, DNDi has delivered three products, fixed-dose antimalarials "ASAQ" and "ASMQ", and a treatment for the advanced stage of sleeping sickness NECT (nifurtimox-eflornithine combination therapy). For more. (JCN Network, Japan)
Nigeria: The NLNG Prize for Science [editorial] Sep 11, 2009
The material that has brought honour to the Fellow of the Nigerian Academy of Science is his seminal work that has discovered the gene responsible for the production of Sialidase (SD), an enzyme that causes Trypanosomiasis, otherwise called sleeping sickness ... In 2006, the World Health Organisaiton (WHO) estimated that more than 60 million people in rural East, West and Central Africa were perpetually exposed to sleeping sickness. (allAfrica.com)
Search reveals no case of human trypanosomiasis in Ghana Sep 5, 2009
WA, Sept. 4, GNA - A search for cases of the Human African Trypanosomiasis (HAT) commonly known as sleeping sickness carried out in the country under the auspices of the Pan African Tsetse and trypanosomiasis Eradication Campaign (PATTEC) has not discovered any active case of the disease in humans. During the search, which was undertaken in the Western and Upper West regions, which are well known for harbouring the flies that are the vectors of the disease, 10,028 blood samples were collected... (Ghana Web, Ghana)
The One Thing Sep 3, 2009
DDT had been amazingly affective at killing mosquitoes, fleas and lice that spread malaria, yellow fever, sleeping sickness, plague, encephalitis, West Nile virus and other diseases. So much so that before the discovery of DDT, in World War I typhus killed more servicemen than bullets. (Fox News)
On Demand picks Aug 27, 2009
(Encore on Comcast) Fascinating, moving, and exhilarating account of a ward full of sleeping sickness patients brought back to life by a miracle drug, only to face unforeseen trouble. Robin Williams, as the empathetic doc, and Robert De Niro, as the most eloquent of the patients, are brilliant. (Boston Globe)
Waiting for Next-Gen Anti-Mosquito Chemicals with Bated Breath Aug 27, 2009
One of the few sensory receptors shared among insects is that for carbon dioxide, including the majority of bloodsucking bugs that pass on diseases from mosquitoes that carry the , yellow fever, dengue and to tsetse flies that harbor sleeping sickness. So Ray and Turner began investigating odorants related to those emitted from ripening fruit that could inhibit carbon dioxide-detection machinery in mosquitoes. (Scientific American)
20% of cattle in Upper West suffer from sleeping sickness Aug 27, 2009
Wa, Aug. 26, GNA - A survey conducted by the Tsetse flies Eradication Project under the auspices of the Pan African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC), has revealed that about 22 per cent of cattle in some parts of the Upper West Region suffered from trypanosomiasis, otherwise known as sleeping sickness ... He said the only sleeping sickness case in recent times was discovered in a baby in the Western region who later died in February this year, but when the mother of the... (Ghana Web, Ghana)
Aiming at genetic cure to disease Aug 20, 2009
Current NanoAxis research projects include using gene therapy for African sleeping sickness, treating seasonal and pandemic influenza such as swine flu, treating Alzheimer s Disease and devising a test kit for cancer and other diseases using quantum dot technology. We hope to take the lead in the area of infectious disease research and believe that use of quantum dots may replace conventional targeting methods such as adenoviral vectors and provide a truly novel form of gene therapy,... (Buffalo Business First, NY)
To Ethiopia and back Aug 18, 2009
The researchers for the International Livestock Research Institute are greatly concerned about cattle that have contracted Trypanosomiasis (sleeping sickness in humans). The animals with the disease, left untreated, become unproductive and very sick. (Storm Lake Pilot Tribune, IA)
New Consortium to Develop Drugs for Neglected Tropical Diseases Aug 17, 2009
LEIDEN, The Netherlands, August 17 /PRNewswire/ -- A new consortium has been formed to boost drug development for the treatment of two deadly diseases, African sleeping sickness and Leishmaniasis, which affect millions of people worldwide ... Rob Leurs (VU University Amsterdam), the project's principal investigator, comments: "African sleeping sickness and Leishmaniasis are diseases caused by parasites. Both diseases are prominent on the World Health Organization's list of neglected tropical... (PR Newswire)
UCSF researchers help crack parasite genome, identify drug leads Jul 16, 2009
Established in 2001, the Sandler Center for Basic Research in Parasitic Diseases is a research consortium at UCSF dedicated to the discovery of affordable, safe and effective drugs to treat the "neglected tropical diseases," including Chagas' disease, sleeping sickness, leishmaniasis and schistosomiasis. For further information, visit. (EurekAlert!)
Core Nuclear Pore Elements Likely Shared By All Eukaryotes Jul 14, 2009
Published June 13 in Molecular & Cellular Proteomics, research performed by former graduate student Jeffrey A. DeGrasse, now at the United States Food and Drug Administration, picked apart the proteins that make up the nuclear pore complex of Trypanosoma brucei, a deadly, single-celled parasite responsible for African sleeping sickness. In the evolutionary tree of eukaryotic life, T. brucei is about as far removed from vertebrates like ourselves as possible, far more distant than commonly used... (Science Daily)
Africa: Neglected Diseases Under the Microscope Jul 7, 2009
The diseases in question account for the deaths of 500,000 people annually, mostly in sub-Saharan Africa, but drug development is biased towards the prospect of high profits, which diseases of the poor like sleeping sickness and visceral leishmaniaisis are unable to offer ... Such is the case for sleeping sickness, a fatal disease that claims an estimated 48,000 people a year in sub-Saharan Africa ... DNDi and its partners developed the nifurtimox-eflornithine combination therapy (NECT), which... (allAfrica.com)
New Insight On Therapy For Devastating Parasitic Disease Jul 3, 2009
28, 2008) Scientists have identified a long-sought chink in the armor of the parasite that causes African sleeping sickness, a parasitic disease that kills at least 50,000 people each. (Apr. (Science Daily)
Chemists Develop Distributed Drug Discovery: Finding Drugs For Neglected Diseases Jun 19, 2009
26, 2007) The neglected tropical diseases are a group of 13 infectious diseases, including elephantiasis, hookworm, African sleeping sickness and trachoma, which affect more than one billion people worldwide ... 16, 2005) Only about 1% of newly developed drugs are for tropical diseases, such as African sleeping sickness and dengue fever. (Science Daily)
EEE Found in Wilkinson County Horse Jun 5, 2009
It 00000C9C 's commonly known as a sleeping sickness in horses. The virus causes inflamation in the brain and spinal cord. (13WMAZ.com, GA)
Knowledge Of Epigenetics Helps Scientists Develop Tool To Study Deadly Parasite’s Histone Code May 25, 2009
In a genome-wide study led by George A.M. Cross, head of the Laboratory of Molecular Parasitology, and T. Nicolai Siegel, a graduate student in the lab, scientists at Rockefeller University have mapped epigenetic changes that are likely to play a role in initiating the transcription of genes in Trypanosoma brucei, the deadly single-celled parasite responsible for African sleeping sickness. The advance marks the first time scientists have been able to develop the tools to map these changes across... (Science Daily)
Satellites and global health: Remote diagnosis May 23, 2009
This vein-measurement indicates the health and size of fly populations and suggests the likelihood of epidemics of sleeping sickness, a tsetse-borne parasitic disease that kills tens of thousands of Africans a year. That means satellite data can be used to predict epidemics without having to collect any flies on the ground. (The Economist)
Genital Stimulation Opens Door For Cryptic Female Choice In Tsetse Flies May 22, 2009
28, 2008) Scientists have identified a long-sought chink in the armor of the parasite that causes African sleeping sickness, a parasitic disease that kills at least 50,000 people each. (July 30, 2008) More than 80 new proteins, thought to play a role in reproductive success, have been discovered in the seminal fluid of fruit. (Science Daily)
Tsetse Fly Costs Agriculture Billions Annually May 13, 2009
The head of the human African trypanosomiasis ("sleeping sickness") programme at the Geneva-based Foundation for Innovative New Diagnostics (FIND), Joseph Ndung'u, told IRIN he left his position as director of the Kenyan Trypanosomiasis Research Institute in order to expand his work beyond Kenya. "But it is true that many scientists [in Africa] are moving away from tsetse flies to other diseases that are seen as more sexy," he said. (allAfrica.com)
Protein That Makes Phosphate Chains In Yeast Revealed; Implications On Crops, Human Diseases Apr 30, 2009
The study, published in Science, uncovers the function of a single protein with a wide range of potential implications ranging from improving crops to fighting diseases such as sleeping sickness ... The research could also pave the way for new treatments for diseases such as sleeping sickness and Chagas disease, as the parasites that cause them need polyphosphate chains to survive. (Science Daily)
American Chemical Society Weekly PressPac -- April 15, 2009 Apr 20, 2009
Those hard-to-treat diseases include leishmaniasis, sleeping sickness, and Chagas disease. These conditions infect millions of people worldwide each year, killing thousands. (EurekAlert!)
Parasite Breaks Its Own DNA To Avoid Detection Apr 20, 2009
19, 2009) The parasite Trypanosoma brucei, which causes African sleeping sickness, is like a thief donning a disguise ... 28, 2008) Scientists have identified a long-sought chink in the armor of the parasite that causes African sleeping sickness, a parasitic disease that kills at least 50,000 people each ... 6, 2006) Researchers have made a crucial breakthrough in the journey towards finding a treatment for African Sleeping Sickness. (Science Daily)
Gains in Sales for Performers of CTV's Broadcast of THE 2009 JUNO AWARDS Apr 15, 2009
Other highlights included Songwriter of the Year Dallas Green teaming up with special surprise guest Gord Downie for a beautiful performance of "Sleeping Sickness" while Canadian music icon Bryan Adams sang "Walk on By" accompanied by Kathleen Edwards on violin. Crystal Shawanda, Divine Brown, Sam Roberts, Sarah McLachlan, Serena Ryder, Simple Plan, The Stills, and collaboration by Canadian folk-rockers Great Big Sea, Hawksley Workman and Eccodek topped off a star-studded show. (Canada Newswire)
Nickelback roars back with a hat trick Mar 30, 2009
City and Colour's Dallas Green received the Songwriter of the Year Award, presented by Buffy Sainte-Marie and k.d. lang, for tracks Waiting, Sleeping Sickness and The Girl from album Bring Me Your Love ... City and Colour was joined by Tragically Hip frontman Gord Downie for Sleeping Sickness, while Crystal Shawanda, Divine Brown and Serena Ryder gave bursts of their respective hits You Can Let Go, One More Chance and Little Bit of Red in quick succession. (Globe and Mail)
Obama's Grandma Fighting Tsetse Fly Scourge Mar 10, 2009
ADDIS ABABA - U.S. President Barack Obama's step-grandmother will use her newfound celebrity status to help eradicate the tsetse fly, an insect that causes sleeping sickness, the African Union (AU) said Monday ... Obama's grandmother recalled a 1968 outbreak of sleeping sickness in her village, it added in a statement ... Some 37 African countries are affected by tsetse and sleeping sickness or trypanosomiasis. (Newsmax)
Gut Parasites That Can Infect Humans May Be Widespread In Domestic And Wild Animals Feb 23, 2009
Two species cause sleeping sickness, a disease that threatens all of. . (Science Daily)
More Funds Needed for Lesser Known Tropical Diseases Feb 7, 2009
Diseases such as sleeping sickness, leishmaniasis and Chagas disease affect more than 13 million people around the world each year but collectively received only 4. 9 percent of total funds. (MEDLINEplus)
A company prospers by saving poor people's lives Feb 7, 2009
And there was a market in tsetse fly traps; the flies, which transmit sleeping sickness, are drawn to certain wavelengths of blue light, so the company had to make fabric of the right shade that did not fade in sunlight and did not weaken when permeated with insecticide. In 1998, they became a supplier to the Carter Center, which was founded by former President Jimmy Carter and was leading the global effort to eliminate guinea worm. (International Herald Tribune)
