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    News, Reviews, and Articles on Sepsis

    Archives: Sepsis

    Stryker Craniomaxillofacial Issues Nationwide Recall of its Custom Cranial Implant Kits; Catalogue Numbers 54-00101, 54-00102, 54-00103 and 54-00104, all lots shipped sterile  Jan 1, 2009
    g., meningitis), intracranial abscess, wound infection, sepsis, re-operation with revision of cranioplasty, long-term neurological deterioration, additional hospitalization, or long-term intravenous antibiotic treatment. Death can occur if an infection is not diagnosed quickly. (U.S. Food and Drug Administration -- Alerts)

    8 Carroll performances that rocked 2008  Dec 26, 2008
    Shelley Ensor, a longtime Common Ground performer and participant, needed both of her legs and nine of her fingers amputated following a bout with sepsis. She was admitted to St. Agnes Hospital in Baltimore with a high fever in March. (Carroll County Times)

    Cytokinetics Retains Development and Commercialization Rights to Ispinesib and SB-743921  Dec 25, 2008
    The most common grade 3/4 adverse events observed in the 50 patients evaluable for safety were neutropenia (21 patients), febrile neutropenia (4 patients) and neutropenic sepsis (1 patient). Development status of SB-743921. (PR Newswire)

    Mom Captures Daughter's Life-Saving Angel in Photo  Dec 25, 2008
    Then she had sepsis and blood clots, staph infections, E. coli, a collapsed lung and feeding problems. In October, doctors wondered whether to take Chelsea off of the ventilator. (Fox News)

    Photo captures image of an 'angel' in hospital...  Dec 25, 2008
    Over the next six weeks in the hospital, Chelsea faced one threat after another: pneumonia in her left lung, then her right lung, then sepsis, blood clots, staph infections, E. coli, a collapsed lung and feeding problems. In late October, doctors met with the family to discuss a plan of action, Colleen said. (The Drudge Report)

    Deaths prompt facility shutdown  Dec 23, 2008
    Reports show that she died of sepsis, Melissa Livezey, spokeswoman for the Upper Moreland police, said. Curtain's sheets appeared to be dirty with blood and puss, her mattress was ripped on both sides and the floor was stained, the report added. (Springfield Sun, PA)

    Clara Mary Andreotti  Dec 20, 2008
    A memorial service will be at 3 p.m. Saturday, Dec. 20, 2008, in Portland Foursquare Church for Sam Swofford of Gladstone, who died Dec. 17 of sepsis at age 30. Sam Swofford was born April 13, 1978, in Portland. (OregonLive, OR -- News)

    Parents Be Aware This Holiday Season: Magnets In Children's Toys Pose Significant Health Risk  Dec 17, 2008
    One child died of sepsis before any surgery or endoscopy could be performed. The study, a follow up to research started in 2004, concludes that public education is the best line of defense in preventing cases like those studied here. (Science Daily)

    Study Finds DOXIL(R) Combination Therapy Delays Disease Progression for Patients With Metastatic Breast Cancer  Dec 15, 2008
    Text hiding to spacing. SAN ANTONIO, Dec. 14 /PRNewswire/ -- Results from a Phase 3 study show that patients with metastatic breast cancer who were treated previously with an anthracycline in the adjuvant setting experienced a significant improvement in time to disease progression (TTP) and overall response rates after receiving a combination of DOXIL(R) (doxorubicin HCl liposome injection) and docetaxel as compared to docetaxel alone. (PR Newswire)

    Gleevec* leads to longest survival reported for patients with life-threatening form of leukemia, 7-year IRIS data show  Dec 11, 2008
    Rare/serious adverse reactions include: sepsis, pneumonia, depression, convulsions, cardiac failure, thrombosis/embolism, ileus, pancreatitis, hepatic failure, exfoliative dermatitis, angioedema, Stevens-Johnson syndrome, renal failure, fluid retention, edema (including brain, eye, pericardium, abdomen and lung), hemorrhage (including brain, eye, kidney and gastrointestinal tract), diverticulitis, gastrointestinal perforation, tumor hemorrhage/necrosis, hip osteonecrosis/avascular necrosis.... (Canada Newswire)

    Dacogen(R) (decitabine for injection) Data Presented on a Phase II Clinical Trial in Elderly Patients with Acute Myeloid Leukemia (AML)  Dec 9, 2008
    Besides myelosuppression, the most commonly reported adverse events considered possibly related to decitabine treatment were febrile neutropenia, fatigue, pneumonia, sepsis, dyspnea and bacteraemia. The five-day dosing regimen of Dacogen(R) is currently being further evaluated in a global, Phase III survival study in elderly patients with AML.. (PR Newswire)

    New Diagnostic Tool Could Slash Malaria Deaths  Dec 9, 2008
    Thinking that the process of cerebral malaria involved sepsis (inflammation) similar in some ways to blood vessel growth in tumours, it was an educated guess to see if there was a relationship, Liles recalled. Developing such biomarkers and diagnostic tools can dramatically improve treatment while reducing overall costs by a more effecient use of limited resources, he said. (Australia.TO)

    Phase III Trial Results Show Elitek(R) (rasburicase) Significantly Reduced Plasma Uric Acid Levels versus Allopurinol in Adults with Hematologic Cancers at Risk for Tumor Lysis Syndrome  Dec 7, 2008
    The most common serious adverse reactions regardless of the relationship to the study drug were neutropenic sepsis (5. 4% / 1. (PR Newswire)

    Flesh-eating Bacteria: Blood Tests Can Help Detect Presence Of Necrotizing Soft Tissue Infections  Dec 6, 2008
    The infection caused severe sepsis, rapid. . (Science Daily)

    State school improvements being made before report  Dec 5, 2008
    And in the one-year period ending in September, as many as 53 deaths in the facilities were due to potentially avoidable conditions such as pneumonia, bowel obstructions or sepsis, the Justice Department said. Fedorov said the agency is making an effort to improve staff retention and training and to place more clients in group homes. (Brenham Banner, TX)

    Radiation Sickness  Dec 4, 2008
    Bowel necrosis may occur, leading to sepsis. Hair loss is common. (Suite101.com)

    Texas out of step on mental health care  Dec 4, 2008
    And in the one-year period ending in September, as many as 53 deaths in the facilities were due to potentially avoidable conditions such as pneumonia, bowel obstructions or sepsis, the Justice Department said. Some families tell horror stories of their loved ones in the state facilities. (MSNBC -- Health)

    Novel Target For Therapeutics Against Staph Infection  Dec 4, 2008
    Once occurring more commonly in healthcare facilities, but now affecting segments of the general population, MRSA is a bacterial pathogen responsible for a range of diseases from mild skin infection to life-threatening sepsis ... The infection caused severe sepsis, rapid. (Science Daily)

    Over 50 dead in Texas due to awful patient care  Dec 3, 2008
    Although many residents are considered medically fragile, at least 53 deaths were from possibly avoidable conditions such as pneumonia, bowel obstructions or sepsis, according to the letter. Slide show. (MSNBC -- Health)

    Justice: Texas fails to protect patients in state schools  Dec 3, 2008
    She noted that 114 residents died in the past year, including at least 53 deaths from aspiration, pneumonia, sepsis, bowel obstruction and other "preventable conditions that are often the result of lapses in care or failure to put medical interventions in place in a timely manner.". More than 800 employees have been suspended or fired for abusing residents since 2004, the report said. (Houston Chronicle)

    Super bug stalks area, state hospitals  Dec 1, 2008
    And its effects -- diseases ranging from severe diarrhea to deadly sepsis -- are worse if the patient has been taking antibiotics. "What happens is the antibiotic you will give them will damage or destroy the friendly bacteria" that can fight off C. diff, said Dr. Richard Duma, director of infectious diseases at Halifax Health. (Daytona Beach News Journal)

    Emergency department reforms 'daft'  Nov 29, 2008
    An elderly person with urinary sepsis might be seriously ill without appearing so, as might another patient who appeared merely confused but who in fact had had a stroke. Someone with a cut from peeling potatoes might well appear less serious but in fact have a severed tendon, which could become infected without prompt treatment, Dr Nieuwkamp said. (The Australian)

    13.8% mothers follow WHO guidelines  Nov 29, 2008
    Emphasising on boosting up the neonatal care system, she said that leading causes of death include birth asphyxia, sepsis and low birth weight, and essential care of newborn babies should be taken. This essential care includes clean delivery practices, facilities for neonatal resuscitation, breastfeeding, provision of warmth, prevention of infection and extra care of the low birth weight baby. (Times of India)

    Helsinn Healthcare and Zealand Pharma Sign a Partnering Agreement for ZP1846, a Novel GLP-2 Agonist  Nov 28, 2008
    Chemotherapy-induced diarrhea is a serious debilitating condition affecting patients undergoing treatment with anti-cancer therapies and this gastrointestinal injury may lead to serious complications such as malnutrition, sepsis, dehydration and kidney insufficiency. There is a strong need for drugs that are able to prevent or treat the mucosal damage and eliminate the diarrhea induced by chemotherapy, and we believe that ZP1846 is useful treatment and/or prevention of an unmet medical need like... (PR Newswire)

    A novel target for therapeutics against Staph infection  Nov 28, 2008
    Once occurring more commonly in healthcare facilities, but now affecting segments of the general population, MRSA is a bacterial pathogen responsible for a range of diseases from mild skin infection to life-threatening sepsis. Even with antibiotics, these infections can still be fatal. (EurekAlert!)

    Bartlett brags on nurse nominees  Nov 27, 2008
    According to Cathy Carter, Bartlett's chief nursing officer, Thibodeau has developed many patient protocols including ventilator care and sepsis protocols. "A very highly skilled nurse, Therese has all of the qualities you would want in a nurse assigned to care for your family members," Carter said. (Juneau Empire)

    Docs on alert during meningitis shot shortage  Nov 21, 2008
    Officials are most concerned about bacterial meningitis and sepsis, a bloodstream infection, caused by Hib (Haemophilus influenzae type b) in children under age 5 because of the high risk of death or serious complications, Centers for Disease Control and Prevention epidemiologist Mike Jackson said. Meningitis is the inflammation of the tissue surrounding the brain and spinal cord, and can be caused by viral or bacterial infections. (MSNBC -- Health)

    Better Tracking of a Childhood Infection Needed, Officials Say  Nov 21, 2008
    Infection can cause meningitis, sepsis or pneumonia, leading to brain damage or death. There are several forms, or serotypes, of H. influenzae, said Michael Jackson, an epidemiologist with the Centers for Disease Control and Prevention in Atlanta. (Atlanta Journal-Constitution -- Health)

    Battling Bacteria In The Blood: Mathematical Models Help In Tackling Deadly Infections  Nov 20, 2008
    "It" is bacterial infection in the blood, also called bacteremia, and it's a major part of the very serious illness called sepsis ... Now, new research by a University of Michigan team and their colleagues is tackling the problem at its most basic level, in hopes of finding new and more effective ways to treat bacteremia and sepsis ... Better treatment for bacteremia and sepsis, then, might include strategies that can help the body filter bacteria out of the bloodstream and into these areas. (Science Daily)

    If a Baby Has a Fever, Treatment All Depends  Nov 18, 2008
    In the worst cases, bacteria get into the bloodstream, from a urinary infection or a skin infection for example, and cause bacterial sepsis ... D. If the baby looks sick, send him to the emergency room for a spinal tap and a full sepsis workup and admit him to the hospital for intravenous antibiotics while waiting to see if any of the cultures are positive for bacteria. (Atlanta Journal-Constitution -- Health)

    Integrating Adult Vaccines into Your Routine Care  Nov 17, 2008
    Pneumococcal disease can cause pneumonia, meningitis and bloodstream infection, known as sepsis; it kills up to 5,000 Americans every year. One in Three Adults are Not Concerned about Spreading Illness to Their Friends, Family Members and Co-Workers. (Pekin Times, IL)

    MRSA's toll climbs, but hospital is slow to change  Nov 17, 2008
    It lists sepsis, kidney failure, liver failure, burns to 35 percent of his body. But there's not a word about MRSA, not even in the box for "other significant conditions.". (Seattle Times)

    Bone Marrow Transplant Might Cure HIV?  Nov 14, 2008
    This procedure puts a patient at high risk of infections, sepsis, and septic shock because they may go for several weeks without an important number of white blood cells. Practically, patients risk death because they have no immune system until the stem cells grow and replace the missing ones. (eFluxMedia)

    Medical Simulation Corp. announces partnership with University of South Florida  Nov 13, 2008
    The SimSuite Sepsis, Ventilator-Associated Pneumonia and Central Line Infection and Management Programs focus on early identification and effective treatment of these widely recognized and costly conditions to improve the confidence and competenceTM of all healthcare providers. . (EurekAlert! -- Business News)

    Novant, CMC honored for improved care  Nov 13, 2008
    CMC, which is part of the Charlotte-based , was honored for its protocol in treating severe sepsis and septic shock in the emergency department. The awards were presented by the Joint Commission, an Illinois-based nonprofit that provides accreditation and certification programs to U.S. health-care organizations. (Charlotte Business Journal, NC)

    Doctors 'rely on chemo too much'  Nov 12, 2008
    But it found that in 27% of cases it hastened or caused death - the toxic nature of the treatment can lead to a range of problems, the most serious of which is an infection called neutropenic sepsis. Report co-author Dr Diana Mort said doctors should be more "cautious in prescribing chemotherapy for very sick patients". (BBC News)

    For some military families, a long goodbye  Nov 11, 2008
    Kevin Mowl of Pittsford, N.Y., on patrol in February 2007, six months before being seriously injured. By Maya Alleruzzo, AP. (USA Today)

    Rice Can Trigger Severe Gut Reaction in Infants  Nov 6, 2008
    The message, Kemp said, is for doctors to be aware that rice can cause FPIES, which is often misdiagnosed as sepsis -- an infection in the bloodstream -- or an acute abdominal problem requiring surgery. Children with FPIES often have several episodes before the problem is diagnosed, Kemp and his colleagues note, and knowing that rice is a potential cause of severe digestive symptoms may lead to earlier diagnosis. (MEDLINEplus)

    Meningitis often leads to long-term problems  Nov 4, 2008
    NEW YORK - Children who survive a bout of meningococcal sepsis, a life-threatening infection, often suffer from long-term medical problems, including mental retardation and other brain impairments, according to a study from the Netherlands. Meningococcus bacteria are the most common cause of meningitis, an infection of the brain and spinal cord. (MSNBC -- Health)

    Emergency-room nightmares spur calls for action  Nov 4, 2008
    "We've had people have heart attacks in the waiting room, we've had sepsis [blood poisoning] in the waiting room, people seize in the waiting room and patients have miscarriages in the waiting room," Dr. Rowe said in an interview. "It's like a Third World country. And this is not unique to Edmonton. This is right across the country.". (Globe and Mail -- Business)

    Hub with US help to end public health woes  Nov 4, 2008
    We will work on large-scale surveillance studies of neonatal infection in hospitals and in the community, training of physicians and other paramedical workers on essential newborn care and resuscitation to prevent birth asphyxia, pro-biotic studies to prevent neonatal sepsis and other infections, and surveillance of tobacco use during pregnancy and knowledge of women on associated health hazards, said N.K. Ganguly, the president of the board of the institute. It will open new doors for future... (Calcutta Telegraph)

    Lung airway cells activate vitamin D and increase immune response  Nov 4, 2008
    "Controlling inflammation through vitamin D is good because too much inflammation can cause problems such as sepsis and seems to contribute to autoimmune disease.". Hansdottir noted that vitamin D insufficiencies and deficiencies (which are more severe) are fairly common, particularly for people living in northern latitudes. (EurekAlert!)

    Nature study demonstrates that bacterial clotting depends on clustering  Nov 3, 2008
    The discovery will improve scientists' understanding of coagulation during bacterial infections and may lead to new clinical methods for treating serious medical conditions such as sepsis and anthrax. It has long been known that blood often coagulates during sepsis or bacterial infections, but this has generally been regarded as a host's immune and inflammatory response. (EurekAlert!)

    Infection and Sepsis  Nov 2, 2008
    Sepsis is a potentially life-threatening clinical phenomenon in response to a massive infection. Sepsis refers to the body's systemic inflammatory response to infection ... Sepsis is considered a serious and possibly life-threatening phenomenon that warrants prompt treatment. (Suite101.com)

    New Study Shows that PEGASYS(R) Regimen Provides Higher Sustained Virological Response Rates for Hepatitis C Patients  Nov 2, 2008
    Serious adverse events in hepatitis C trials included neuropsychiatric disorders (homicidal ideation, suicidal ideation, suicide attempt, suicide, psychotic disorder and hallucinations), serious and severe bacterial infections (sepsis), bone marrow toxicity (cytopenia and rarely, aplastic anemia), cardiovascular disorders (hypertension, supraventricular arrhythmias and myocardial infarction), hypersensitivity (including anaphylaxis), endocrine disorders (including thyroid disorders and diabetes... (PR Newswire)

    'Old Blood' Linked To Infection  Nov 2, 2008
    In a new study presented at CHEST 2008, the 74th annual international scientific assembly of the American College of Chest Physicians (ACCP), researchers found that patients who received transfusions with blood stored for 29 days or more were twice as likely to suffer from nosocomial infections, including pneumonia, upper respiratory infections, and sepsis, with the oldest blood being associated with the most infections. Currently, federal regulations allow red blood cells to be stored up to 42... (Science Daily)

    Probiotics: More hype than help for your belly?  Nov 1, 2008
    But if you have an underlying illness or a compromised immune system, check with a physician before consuming probiotics since they may increase your risk for infections such as sepsis, an infection of the bloodstream. Although there are several studies done which administer probiotics to newborns, and even premature babies, a newborn does not have an established microbiota or immune system. (MSNBC -- Health)

    Older Blood Boosts Chances of Infection in Transfusion Patients  Oct 30, 2008
    The research team found that, following transfusion, 11 percent of the patients died, while 57 patients went on to develop one or more serious infections, including pneumonia, upper respiratory infection, sepsis and/or shock. Specifically, 32 patients developed a single infection, 21 developed two such infections, and four patients developed three infections. (MEDLINEplus)

    * Council of Agriculture trumpets vaccine success  Oct 30, 2008
    When affected, a young bird develops symptoms such as ocular and nasal discharges, tremors of the head and neck, sepsis and a cheese-like excretion around the heart, Chao said. Even if a duckling or young goose survives, its compromised immune system causes retarded growth, which means that the bird is worthless on the market, Chao said. (Taipei Times, Taiwan -- World)

    Statins Associated With Lower Risk Of Death From Pneumonia  Oct 30, 2008
    A recent review article indicated that statins may benefit patients with sepsis (infection of the bloodstream) or bacteremia (presence of bacteria in the bloodstream), possibly due to the medications' anti-clotting, anti-inflammatory or immune-modifying properties ... These effects may especially benefit patients with sepsis and bacteremia, which are associated with early death from pneumonia. (Science Daily)

    Etanercept, Methotrexate Safe for Juvenile Rheumatoid Arthritis  Oct 29, 2008
    During the study, one patient taking methotrexate developed lupus, and two cases of sepsis occurred in patients taking etanercept and the combination treatment. There were no cases of lymphoma, malignancy, tuberculosis or death. (MEDLINEplus)

    Honing In On New Strategy To Treat Common Infection  Oct 29, 2008
    29, 2007) A new treatment for Candida species of fungi which can cause thrush and sepsis (a life-threatening infection leading to fever, hypotension, and shock) has proven equally effective as the existing. (Mar. (Science Daily)

    Long-stored blood linked to higher infection risk  Oct 29, 2008
    If the patients got blood stored 29 days or more, they developed blood stream infections, pneumonia, urinary tract infections, heart valve infections, sepsis and other infections at twice the rate of patients getting blood stored for up to 28 days. The blood itself was not infected, but the stored blood's release of chemical agents called cytokines may have affected the recipients' immune systems, rendering them more susceptible to infections, said Dr. Raquel Nahra of Sparks Regional Medical... (Xinhuanet, China)

    Statins May Reduce Pneumonia Deaths  Oct 28, 2008
    Some studies have linked statin use with decreased risk of severe sepsis -- infection of the bloodstream -- or death associated with infections, but there had been conflicting findings on pneumonia, according to Dr. Reimar Thomsen of Aarhus University and Aalborg Hospital in Denmark. Thomsen led a new study tracking 29,900 patients treated for pneumonia in Denmark that found that those who were taking statins before hospitalization had a 31 percent lower risk of dying from pneumonia than those... (Newsmax)

    Column: John McCain deserves your vote  Oct 27, 2008
    cfresident wrote on Oct 26, 2008 11:55 PM:" On the Guttmacher website, the last set of data is from 2003 and it says 41.6 million globally. But scroll down and read the rest of the fact sheet; you will get a broader picture that the numbers do not show: Legal restrictions on abortion do not affect its incidence.Where abortion is legal and permitted on broad grounds, it is generally safe, and where it is illegal in many circumstances, it is often unsafe.CONSEQUENCES OF UNSAFE ABORTION Worldwide,... (Chippewa Falls Chippewa Herald, WI)

    In Charli Anna's name  Oct 22, 2008
    It appeared there was a possible sepsis or shut down occurring somewhere in her body. They made the tough decision not to revive her if her heart stopped. (Park Hills Daily Journal, MO)

    UPDATE 2-US calls for new warnings on Genentech skin drug  Oct 19, 2008
    Raptiva, which is approved to treat moderate to severe forms of the scaly skin condition in adults, can also increase the risk of bacterial sepsis, viral meningitis and invasive fungal disease, the FDA said in a statement. "Doctors and other prescribers should carefully evaluate and weigh the risk/benefit profile of Raptiva for patients who would be more susceptible to these risks," Janet Woodcock, head of the FDA's Center for Drug Evaluation and Research, said. (Reuters)

    Safety Issues Prompt FDA Changes to Psoriasis Drug Label  Oct 18, 2008
    Known as a boxed warning, the new label notes that Raptiva (efalizumab) can increase the risk of bacterial sepsis, an infection of the bloodstream; viral meningitis, which affects the brain; invasive fungal infections, which can damage the lungs or other areas of the body; and a condition known as progressive multifocal leukoencephalopathy (PML), a viral infection of the brain. Several people taking Raptiva have been hospitalized and some have died due to these infections, according to the FDA.. (Health.com)

    Head of State  Oct 17, 2008
    But insights derived from modern understanding of concussions, coma, strokes, sepsis, and the damage they do to brain tissue and the effects these incidents have on human emotions and behavior casts these particular rulers in a very different light. Coming of age in Plantagenet times involved putting an iron bucket over your head and flailing about with broadswords, clubs, maces, and an assortment of heavy objects in the direction of other young men similarly accessorized, until you or your... (The American Conservative)

    Psoriasis Drug Raptiva Gets FDA Warning  Oct 17, 2008
    Bacterial sepsis: a blood infection that can affect organs throughout the body. Viral meningitis: a brain infection. (WebMD)

    Breast cancer awareness month spotlights oral mucositis: Side effect of anticancer therapy  Oct 17, 2008
    Severe ulceration may cause breaks in the mucosa, which can then become susceptible to oral opportunistic infections, possibly resulting in bacteremia (the presence of bacteria in the blood), sepsis (the presence of pathogenic microorganisms in the blood) or other potentially fatal complications. The economic impact of mucositis can be significant, as the need for prolonged hospital stays, nutritional therapy and treatments for pain and infection can drive up the costs of therapy. (EurekAlert!)

    Gundersen Lutheran earns top marks in care report  Oct 16, 2008
    The hospital was rated poor in the report on heart failure, pneumonia, sepsis and stroke ... More than half of the Medicare patient deaths were associated with four conditions: sepsis, a systemic response to infection; pneumonia; heart failure; and respiratory failure ... Gundersen Lutheran: Appendectomy, bariatric surgery, bowel obstruction, chronic obstructive pulmonary disease, diabetic acidosis and coma, heart attack, heart failure, hip fracture repair, pancreatitis, pneumonia, respiratory... (La Crosse Tribune, WI)

    "Good" Bacteria Unlikely to Curb Eczema  Oct 15, 2008
    "Probiotic treatment is generally safe, however it can lead to adverse events including sepsis and bowel ischaemia -- the precise risk of such events is difficult to quantify, but is likely to be very low for most people," Boyle and his team write. In a written statement accompanying the report, Boyle concludes: "Further probiotic eczema treatment studies would help to clarify whether specific probiotic strains have a greater effect on eczema severity and symptoms than the strains studied to... (MEDLINEplus)

    Heart Hospital of Austin Ranked #1 in Texas and Top 5% in the Nation for Overall Cardiac Services Six Years in a Row  Oct 14, 2008
    More than half of those preventable deaths were associated with four conditions: sepsis, pneumonia, heart failure and respiratory failure. While overall death rates declined from 2005 to 2007, the nation's best-performing hospitals were able to reduce preventable deaths at a much faster rate than poor-performing hospitals, resulting in large state, regional and hospital-to-hospital variations in the quality of patient care, the study found. (PR Newswire)

    Death rate 70 percent lower at top-rated hospitals: HealthGrades annual hospital quality study  Oct 14, 2008
    More than half of those deaths were associated with four conditions: sepsis (a life-threatening illness caused by systemic response to infection), pneumonia, heart failure and respiratory failure ... Fifty-four percent (128,749) of the potentially preventable deaths were associated with just four diagnoses: Sepsis, heart failure, pneumonia and respiratory failure ... In the study's analysis of hospital death rates, the following 17 procedures and conditions were analyzed: bowel obstruction,... (EurekAlert!)

    Probiotics unlikely to relieve eczema symptoms  Oct 14, 2008
    The researchers say while probiotic treatment is generally safe, it can lead to adverse events including sepsis and bowel ischaemia, which is likely to be very low for most people. Dr Boyle says further studies of new probiotics are needed, because it is possible that different types of probiotics which haven't yet been studied in eczema treatment could be more effective. (News-Medical.net)

    Why could ethyl pyruvate attenuate severe acute pancreatitis?  Oct 11, 2008
    EP was proved could inhibit HMGB1 release from macrophages and prevent the accumulation of serum HMGB1 levels in mice with lethal sepsis through inhibiting NF- kappaB and p38 MAPK signaling. The research, performed by this team, investigated whether delayed EP therapy attenuates experimental SAP via reducing serum HMGB1 levels in rats or not. (EurekAlert!)

    Statins may prevent miscarriages  Oct 11, 2008
    Tissue factor expression on cells that line the circulatory system and certain immune cells is a characteristic feature of acute and chronic inflammation in conditions such as sepsis, atherosclerosis, Crohn's disease, and lupus. Finding a way to manipulate tissue factor and PAR2 could lead to treatments for these diseases. (EurekAlert!)

    Early Mobility Best for ICU Patients  Oct 10, 2008
    Based on a review of 24 studies of ICU patients with sepsis, prolonged mechanical ventilation and multiple organ failure, nearly half of the 1,421 patients had neuromuscular dysfunction associated with extended use of mechanical ventilation and lengthy ICU stays. In other studies Needham reviewed, the use of early physical medicine and rehabilitation therapy for ICU patients -- even those on life support -- safely helped patients to get up and about more quickly. (MEDLINEplus)

    New Drug Target For Inflammatory Disease Discovered  Sep 25, 2008
    25, 2008) UC Davis researchers have defined a cellular process that promotes inflammation and, at the same time, found an important starting point for identifying and testing new drugs for diseases such as sepsis, rheumatoid arthritis, cardiovascular disease and some cancers. See also. (Science Daily)

    The role of polyclonal intravenous immunoglobulin in treating HIV-positive children with severe bacterial infections: a retrospective cohort study  Sep 24, 2008
    2 years) met inclusion criteria; lower respiratory tract infection was diagnosed in 94 (67%) of the children, while 74 (53%) had bacterial sepsis. Fifty-four (39%) children were receiving antiretroviral therapy and 39 (28%) were receiving tuberculosis treatment. (BioMed Central)

    Spectral to bring anti-sepsis therapy to the U.S. market  Sep 23, 2008
    TORONTO, Sept. 23 /CNW/ - Spectral Diagnostics Inc. (TSX: SDI) today announced that it has agreed to key terms with Toray Industries Inc. of Japan to obtain the exclusive development and commercial rights in the U.S. for Toraymyxin(TM), a therapeutic for the treatment of sepsis that removes endotoxin from the bloodstream. Under the terms of the agreement, the Company will seek FDA approval for a combined product for the treatment of severe sepsis that will include Toraymyxin(TM) and Spectral's... (Canada Newswire)

    Threat to Use Dog as a Weapon Lands Suspect and Dog in Jail  Sep 23, 2008
    Without treatment, the heartworms take a toll on the animal s organs, and in a few years cause the animal to go into sepsis and eventually die. By threatening to use the dog as a weapon, his former owner started a sequence of events that had in essence sentenced the dog to death. (Dublin Courier Herald, GA)

    From Xbox To T-cells: Borrowing Video Game Technology To Model Human Biology  Sep 19, 2008
    Dr. Gary An, a surgeon specializing in trauma and critical care in Northwestern University's Feinberg School of Medicine, is a pioneer in the use of agent-based modeling to understand another matter of life and death: sepsis. With billions of agents, including a variety of cells and bacteria, these massive, often fatal infections have been too complex to model economically on a large scale, at least until now. (Science Daily)

    BTG to buy Protherics in biotech deal  Sep 18, 2008
    AstraZeneca has a deal dating back to 2005 with Protherics covering its experimental drug CytoFab for sepsis, a deadly syndrome linked to serious bloodstream infections. The Anglo-Swedish group also has a 3. (International Herald Tribune)

    Strategies for preventing gastrointestinal complications in severely burned patients  Sep 18, 2008
    Injury to GI function, especially to GI barrier function, is an important initiator as well as a stimulator for occurrence of systemic inflammatory response syndrome, sepsis and multiple organ dysfunction syndrome following severe burns. With the deeper understanding of GI function and changes in the stereotype of clinical treatment in recent 30 years, a series of new therapies including fluid resuscitation, early escharectomy, continuous renal replacement therapy, and use of glutamine and... (EurekAlert!)

    Listeriosis primer outlines risks, symptoms, treatment  Sep 13, 2008
    For example, blood and urine tests should be done and antibiotics started for pregnant women with a fever or signs of sepsis. The current outbreak of listeriosis has been linked to a Maple Leaf Foods meat processing plant in Toronto. (CBC.ca)

    Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer  Sep 11, 2008
    Sepsis occurred in 9 patients in the cetuximab group and in 1 patient in the chemotherapy-alone group (P=0. 02). (New England Journal of Medicine)

    Prepping for Medicares refusal to cover medical errors  Sep 10, 2008
    A study by the Institute of Medicine of The National Academy of Sciences in Washington, D.C., concluded medical errors add significantly to Medicare hospital payments, ranging from an average of an additional $700 per case to treat bedsores to $9,000 per case to treat post-operative sepsis. Another Institute of Medicine study concluded that medical errors may account for 2. (Milwaukee Business Journal, WI)

    Why Should You Breastfeed?  Sep 3, 2008
    Decreased risk of bacterial meningitis, sepsis, diarrhea, otitis media, respiratory infections, urinary tract infections, asthma, Hodgkin s disease, leukemia, obesity, hypercholesterolemia, sudden infant death syndrome, necrotizing enterocolitis, and diabetes (Types 1 and 2). Developmental. (Suite101.com)

    Patient died from hospital infection  Sep 2, 2008
    A PENSIONER who went into surgery for a hip operation died after contracting hospital-acquired infections Clostridium difficile and MRSA and then E coli. "That does not leave the DGH smiling though because clearly that infection transmitted to one other person or more there."This shows what a dangerous organism we are dealing with. (Eastbourne Today)

    NHRC issues notice to AIIMS  Aug 30, 2008
    The statement then went on to say, "The medicines for treatment of high BP, namely - valsartan and olmesartan - have been marketed in India for over three years. These drugs have relatively much less side-effects than other drugs for blood pressure. This group of medicines has been safely and effectively used with children having high blood pressure worldwide. The 49 deaths reported occurred in children with sepsis, and those with respiratory failure receiving life support. The deaths were due... (Times of India)

    Doggie 'docs' diagnose owners' ills  Aug 28, 2008
    She was diagnosed with sepsis and spent a week in the hospital recovering from the infection that started in her leg and spread through her body. Sensitive dogs, such as Morgan, are proving that besides being mans best friend, some canines also have a lifesaving sixth sense. (MSNBC -- Health)

    How Wecht served 2 sides in malpractice suit  Aug 10, 2008
    In his original autopsy report, dated March 22, 1996 -- the day after the girl died -- Dr. Wecht found she had sepsis and concluded she died from "complications of an acute, overwhelming viral infection." ... Because Dr. Wecht had concluded the girl had sepsis, he was hired by Dr. Chauhan to support his claim that there was no Reye's syndrome. (Pittsburgh Post-Gazette, PA)

    Integrating Adult Vaccines into Your Routine Care  Aug 5, 2008
    Pneumococcal disease can cause pneumonia, meningitis and bloodstream infection, known as sepsis; it kills up to 5,000 Americans every year. One in Three Adults Are Not Concerned about Spreading Illness to Their Friends, Family Members and Co-workers. (Canton Daily Ledger, IL)

    Archives: Sepsis

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