Promising New Path For Treating Traumas Discovered Oct 27, 2009
His work with OMRF researcher Fletcher Taylor, M.D., led to the creation of Xigris, a treatment for severe sepsis. And with his wife and colleague, Naomi Esmon, Ph. (Science Daily)
Antibody 'fixes internal bleeds' Oct 26, 2009
Writing in the journal, Nature Medicine, the OMRF researchers found that when mice had a bad blood stream infection (sepsis), their blood contained high levels of histones ... The OMRF team have tested the antibody in mice with sepsis and it does stop the toxic effects of the histones and they recover, the researchers say. (BBC News -- Americas)
Canadian scientists link fat hormone to death from potentially deadly blood infection Oct 24, 2009
Adiponectin found in body fat may hold the key to preventing and treating sepsis. A new Canadian study has found that lower-than-normal levels of a naturally-occurring fat hormone may increase the risk of death from sepsisan overwhelming infection of the blood which claims thousands of lives each year ... o Sepsis could be prevented if the animals were given additional adiponectin. (EurekAlert!)
Father convicted in baby's death Oct 24, 2009
Frost and Assistant Public Defender Ingrid Effman presented expert medical witnesses who testified that Matthew Thomas died from sepsis, an aggressive bacterial blood infection, and not from trauma to his brain. The defense also attacked the police tactics the jury viewed in nearly nine hours of videotaped police interrogations, the first time such evidence was used in a county murder trial. (Albany Times Union)
Scientists create NICE solution to pneumonia vaccine testing problems Oct 23, 2009
The leading cause of pneumonia worldwide is the pneumococcus bacterium, which also causes meningitis, sepsis and other complications. Pneumococcus has more than 90 strains that vary by geographic region and change over time. (EurekAlert!)
Valley delays school-based vaccines for H1N1 virus Oct 21, 2009
Curran had just admitted a 10-year-old patient into St. Joseph's Medical Center after the boy developed pneumococcal sepsis, a bacterial pneumonia that spread to his lungs. The boy also was growing the H1N1 virus in his lungs, Curran said. (AZCentral -- News)
Compound Shows Potential For Slowing Progression Of Lou Gehrig's Disease Oct 21, 2009
20, 2009) A chemical cousin of a drug currently used to treat sepsis dramatically slows the progression of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, in mice ... Zlokovic says the form of APC currently used to treat sepsis carries an increased risk of bleeding and likely will not be appropriate for treating ALS in humans. (Science Daily)
What is the Spleen? Oct 17, 2009
You will, however, be at greater risk of infection from sources such as pneumococcal pneumonia and sepsis ... While long-term antibiotic treatment may not be necessary for most adults, it is a vital protection to prevent sepsis for those who are active around dogs ... A bite from a dog carrying the C. canimorsu bacteria can bring about sepsis and a long, difficult recovery from fever, rash, diarrhea, vomiting, severe fatigue, and possible death in 15-30% of cases. (Suite101.com)
Expert: Baby could've been saved Oct 15, 2009
Defense attorney Ingrid Effman told jurors in opening arguments that sepsis, a serious bacterial infection of the blood, caused Matthew's death and could have also caused the swelling of the brain. OTHER STORIES. (Albany Times Union)
Video: They were all lies Oct 15, 2009
Effman has told jurors that Matthew died of complication from sepsis, an infection of the blood and not from anything Thomas did. The trial continues today. (Albany Times Union)
St. Lukes No. 1 in state for critical care Oct 15, 2009
St. Luke s said it is the only hospital in Missouri named in the top 5 percent for critical care services, which includes treating severe conditions such as respiratory failure and sepsis. St. Luke s Hospital, led by President and Chief Executive Gary Olson, has 493 beds and specializes in 60 areas, including cardiovascular care and surgery, cancer care, neurosurgery and neurology, orthopedics, maternity and other women s health, general medicine, outpatient services, pediatrics and... (St. Louis Business Journal, MO)
Bans 'do not cut abortion rate' Oct 14, 2009
The costs of unsafe abortions, which can include inserting pouches containing arsenic to back street surgery, can be high: the healthcare bill to deal with conditions from sepsis to organ failure can be four times what it costs to provide family planning services. COUNTRIES WHERE ABORTION HAS BEEN RESTRICTED 1997: Poland re-instated law outlawing abortion except when mother's life at risk or she had been raped 1998: El Salvador outlaws all abortions even when mother's life at risk 2006:... (BBC News -- Health)
Psoriasis: A Nuisance or a Deadly Disease? Oct 14, 2009
That clears psoriasis, but as you take them off of the steroids, you can develop a horrific flare where your body gets covered head to toe with red skin, or covered with puss pimples Many of these patients will grow bacteria in their blood and can actually die from sepsis. Problems Associated With Psoriasis. (Fox News)
HealthGrades study: 52 percent lower chance of dying at top-rated hospitals Oct 13, 2009
Approximately 57% (127,488) of the potentially preventable deaths were associated with just four diagnoses: sepsis (44,622); pneumonia (29,251); heart failure (26,374) and respiratory failure (27,241). Over the last three studies, Ohio and Florida consistently have had the greatest percentage of hospitals in the top 15% for risk-adjusted mortality. (EurekAlert!)
Milk Protein Supplement May Help Prevent Sepsis In Very Low Birth-weight Infants Oct 9, 2009
8, 2009) Very low birth-weight newborns who received the milk protein lactoferrin alone or in combination with a probiotic had a reduced incidence of late-onset sepsis, according to a study in the October 7 issue of JAMA. ... Late-onset sepsis, i.e., infections arising after the perinatal period (immediately before and after birth), mainly occur in the hospital and affect 21 percent of very low birth-weight (VLBW; less than 3 ... Whether lactoferrin can reduce the incidence of sepsis is unknown.... (Science Daily)
Cow's Milk Protein Could Help Save Preemies' Lives Oct 8, 2009
That's the conclusion of a study published in the Oct. 7 issue of the Journal of the American Medical Association that found when these tiny newborns were given a daily dose of the milk protein lactoferrin along with a probiotic bacteria during the first weeks of life, the incidence of the blood infection sepsis dropped dramatically. "Prevention of sepsis in neonates can be achieved through supplementation of a simple, easily available, cost-effective intervention that is well-tolerated and may... (MEDLINEplus)
Africa: Putting Faith in Mid-Level Workers Paying Off Oct 6, 2009
Globally, 75 percent of maternal deaths are the result of five direct causes - hemorrhage, obstructed labor, sepsis, eclampsia (high blood pressure accompanied by fluid retention which leads to seizures of a coma) and unsafe abortion. Many more women suffer serious, permanent injuries and disabilities during pregnancy and delivery. (allAfrica.com)
Ky. football coach acquitted in player death Sep 18, 2009
He died three days later at a Louisville hospital of heat stroke, sepsis and multiple organ failure. His temperature reached at least 107 degrees. (MSNBC -- Sports)
NexBio(R) Presents DAS181 (Fludase(R)*) Potently Inhibits Novel Swine-Origin A(H1N1) and NAI-Resistant Influenza Viruses, at ICAAC 2009 Sep 14, 2009
ViradinTM, invented and developed by NexBio, is a parenteral protein under development, currently at lead optimization stage, directed to the treatment of viral hemorrhagic fevers and bacterial biothreat sepsis. TOSAPTM is a technology invented and developed by NexBio and is used to formulate DAS181 for inhalation, as well as to make nano/microparticles from virtually any type of molecule. (PR Newswire)
New WHO Data Underscores Global Threat Of World's Leading Child Killer: Pneumonia Sep 13, 2009
6 million child deaths worldwide each year are the result of six causes: pneumonia, diarrhea, malaria, neonatal sepsis, preterm delivery and asphyxia at birth. (July 3, 2007) A new study shows Hib vaccine protects children from significant burden of life-threatening pneumonia and meningitis. (Science Daily)
Hutchinson slowly rebounding from summer bout with killer disease Sep 12, 2009
While it is best known as a cause of meningitis, widespread blood infection (sepsis) is more damaging and dangerous. . (Wwuvikings.com)
South Africa: High Maternal and Child Deaths 'Not Acceptable' Sep 11, 2009
"The children are dying of common, preventable diseases, and if we interrogate this a little bit further, the underlying factors giving rise to child mortality are two-fold in terms of patho-physiological processes About 60% of children who die are malnourished and well over half of them are HIV-infected, and this 50% of HIV-infected children are those where we know that they are HIV-infected. There's a proportion of the remainder in whom we suspect, but we haven't confirmed this fact, and then... (allAfrica.com)
Centocor Ortho Biotech Receives FDA Complete Response Letter Regarding DOXIL(R) for the Treatment of Advanced Breast Cancer Sep 11, 2009
Sepsis occurring during neutropenia has resulted in discontinuation of treatment and in rare cases of death. DOXIL may potentiate the toxicity of other anticancer therapies, especially hematologic toxicities, when used in combination with other therapies that suppress bone marrow. (PR Newswire)
Mom of Ky. player who died testifies at rare trial Sep 5, 2009
"Prosecution witness Julian Tackett, an assistant commissioner with the Kentucky High School Athletic Association, testified that coaches can administer water breaks "at their discretion" when the heat index is under 95 degrees. The heat index was 94 degrees the day Gilpin collapsed according to Stinson's practice notes.Gilpin died Aug. 23, 2008, at a Louisville hospital of heat stroke, sepsis and organ failure. Medical examiners opted not to perform an autopsy.The trial, which is expected to... (MSNBC -- Sports)
Early, Aggressive Treatment Recommended For Critically Ill Patients With Hematological Malignancy Sep 3, 2009
Factors associated with an increased risk of death included bone marrow transplantation, Hodgkin's lymphoma, severe sepsis, age, a low haematocrit and length of hospital stay before intensive care admission. Artificial ventilation, however, was not associated with increased mortality, in contrast to previous studies. (Science Daily)
Doctors meet to improve obstetrics care in VR Sep 2, 2009
Dr Amakpa listed severe bleeding; sepsis; eclampsia, which is attack of convulsions, high blood pressure and other complications in late pregnancy; and unsafe abortions as some of the main causes of pregnancy related deaths in the region and elsewhere in Ghana. He said delays in identifying and evaluating danger signs, reaching facilities and giving attention are some of the factors influencing maternal deaths in the region. (Ghana Web, Ghana)
Mom Makes "Miracle" H1N1 Recovery Aug 29, 2009
Woman Put in Coma as Family Told to Expect the Worst; Woman Tells Story of Turnaround on "The Early Show". Cherie Starling was near death after doctors put her in a coma after she contracted a strong case of H1N1 flu. (CBS News)
Coach's trial raises questions about heat deaths Aug 28, 2009
Within three days, he died of multiple organ failure, sepsis and heat stroke. Medical examiners opted not to perform an autopsy. (Anchorage Daily News)
En Banc Federal Circuit to Address Closely Watched Patent Issue Aug 26, 2009
Ariad's suit alleged that Eli Lilly's osteoporosis drug Evista and its sepsis treatment Xigris infringed on different claims of the patent. The en banc rehearing order asked parties and amici to brief the court on two questions. (Law.com)
Recently retired Stetson president Doug Lee dies Aug 26, 2009
After the first surgery, sepsis -- a widespread blood infection -- caused multiple problems. Sepsis has innumerable causes, said Dr. Frank Farmer, a specialist in internal medicine ... Often, because there are so many ways for infection to enter the bloodstream, it's hard to pinpoint the cause of sepsis. (Daytona Beach News Journal)
Adventurer dies on Kauai Aug 24, 2009
He died of acute hemorrhagic pneumonia with sepsis early the next morning while en route to Wilcox Hospital, doctors told George Cox. "I don't think he had any idea of the severity of his illness," George Cox said. (Honolulu Advertiser)
Key feature of immune system survived in humans, other primates for 60 million years Aug 19, 2009
"It's essential that we have both an innate immune response that provides an immediate and front line of defense, but we also have protection against an overreaction by the immune system, which is what you see in sepsis and some autoimmune or degenerative diseases," Gombart said. "This is a very delicate balancing act, and without sufficient levels of vitamin D you may not have an optimal response with either aspect of the immune system.". (EurekAlert!)
Spectral appoints new board member Aug 14, 2009
TORONTO, Aug. 13 /PRNewswire-FirstCall/ - Spectral Diagnostics Inc. (TSX:SDI, a company developing products for the treatment of sepsis, today announced the appointment of Dr. Michael Cross to the Company's Board of Directors ... Spectral is a leader in the battle against sepsis ... With the growing awareness for the role of endotoxemia in sepsis and the increasing number of therapies being developed for this indication, Spectral is well-positioned to drive the adoption of the EAA(TM), which can... (PR Newswire)
Discovery may lead to powerful new therapy for asthma Aug 12, 2009
In disorders such as colon cancer, atherosclerosis, sepsis and uveitis, the Srivastava team has found, cells are hit by a sudden overload of reactive oxygen species (varieties of oxygen and oxygen compounds that are especially eager to react with other molecules). The result is a chain of biochemical reactions that leads the cells' genetic machinery to crank out a barrage of inflammatory signaling proteins. (EurekAlert!)
Red Wine May Fight Inflammation in the Body Aug 4, 2009
Mice that were not pre-treated with resveratrol developed a serious reaction similar to the inflammatory disorder sepsis ... "Strong acute inflammatory diseases such as sepsis are very difficult to treat and many die every day due to lack of treatment," said Alirio Melendez of the University of Glasgow ... "Moreover, many survivors of sepsis develop a very low quality of life due to the damage that inflammation causes to several internal organs," he said. (Newsmax)
Red wine may benefit arthritis patients Aug 3, 2009
Strong acute inflammatory diseases such as [infections like] sepsis are very difficult to treat and many die daily due to a lack of treatment, the Daily Express quoted a researcher from the study as saying. Moreover, many survivors of sepsis develop a very low quality of life due to the damage that inflammation causes to several internal organs, the researcher added. (India Times, India)
Zimbabwe: 364 Die From Pregnancy Aug 3, 2009
The report cited HIV and Aids, hypertension, haemorrhage (severe loss of blood), sepsis and malaria as the top five leading causes of deaths in Zimbabwe ... "Effective interventions exist to treat these complications (haemorrhage, hypertension/eclampsia, sepsis and obstructed labour) and deaths from them are avoidable. "Successful prevention and treatment of these complications represents the potential to reduce maternal deaths by 46 percent. (allAfrica.com)
Healthy secret of red wine uncorked Aug 1, 2009
The study, not only explains resveratrol's one-two punch on inflammation, but also shows how it-or a derivative-can be used to treat potentially deadly inflammatory disease, such as appendicitis, peritonitis, and systemic sepsis. "Strong acute inflammatory diseases such as sepsis are very difficult to treat and many die every day due to lack of treatment," said Alirio Melendez, senior lecturer on the faculty of medicine at Glasgow Biomedical Research Centre in Scotland and one of the researchers... (India Times, India)
Health Care in Crisis: Patients Are Pushovers Jul 30, 2009
Eradicating the sepsis that ensued required an extensive stay in Fort Worth's Kindred Hospital, which specializes in slow-to-heal wounds and infections ... In a Hartmann's, the colon is permanently severed; the section leaving the stomach is brought through the abdomen and skin and the rectum is sealed so that waste can't get into an open bedsore and again cause sepsis ... "If he had, he would have noticed that Don was confined to a wheelchair and had been hospitalized for sepsis and that... (BusinessWeek)
Blue food dye helps heal spinal cord injuries Jul 28, 2009
The only known toxicity is in patients with blood infections known as sepsis. Nedergaard cautioned that tests in humans are likely still years away. (MSNBC -- Health)
Leading Pathogen In Newborns Can Suppress Immune Cell Function Jul 28, 2009
ScienceDaily (July 27, 2009) Group B Streptococcus (GBS), a bacterial pathogen that causes sepsis and meningitis in newborn infants, is able to shut down immune cell function in order to promote its own survival, according to researchers at the University of California, San Diego School of Medicine and the Skaggs School of Pharmacy and Pharmaceutical Sciences. See also. (Science Daily)
Manslaughter acquittal in faith-healing case Jul 24, 2009
Theyre not monstersBut the defense attacked the credibility of the state's expert witnesses and said the child died of a fast-moving form of sepsis, an infection. The Worthingtons testified that the cyst was a trait in the father's family and that they thought their child only had a cold. (MSNBC -- Crime)
Jury in Oregon faith-healing trial reports deadlock Jul 21, 2009
They said she died of an infection, sepsis, that coursed through her body in hours. The growth on her neck was something others in the Worthington family had suffered with no ill effect, and it seemed to cause her no pain, her parents testified. (Longview Daily News, WA)
Huge Surge in Deaths of Mothers in South Africa Jul 20, 2009
4%), pregnancy-related sepsis (9%) and pre-existing maternal disease (6%) were the other main killers. Of the deaths that could have been avoided, the report points to the need for better management of "complications of hypertension, obstetric haemorrhage, pregnancy related sepsis and non-pregnancy related infections" ... Deaths due to non-pregnancy related infections peak at 25-29 years and this peak is mirrored in deaths due to complications of abortion and pregnancy related sepsis following a... (allAfrica.com)
Amgen Announces KRAS Safety Update to U.S. Prescribing Information for Vectibix(R) (Panitumumab) Jul 18, 2009
Subsequent to the development of severe dermatologic toxicities, infectious complications, including sepsis, septic death, and abscesses requiring incisions and drainage were reported. Infusion Reactions: Severe infusion reactions occurred in approximately 1 percent of patients. (PR Newswire)
How Staph Infections Alter Immune System Jul 17, 2009
The infection caused severe sepsis, rapid. . (Science Daily)
First U.S. double hand transplant has a simple goal Jul 17, 2009
Sepsis set in both his lower legs and hands, and doctors ultimately had to amputate both legs below the knee and both arms below the elbow. The ex-airman adjusted to life on prosthetic legs and basic prosthetic arms that ended in hooks. (MSNBC -- Health)
Cystic Fibrosis - Liposomal Tobramycin Receives Second Orphan Drug Designation Within Weeks Jul 16, 2009
Despite stringent infection control practices, B. cepacia infections still occur in cystic fibrosis patients and can lead to fatal sepsis. The cell envelopes of these especially virulent bacteria are impermeable to most antibiotics, which makes them particularly difficult to treat. (PR Newswire)
Oregon faith-healing case nearly ready for jury Jul 15, 2009
The defense, however, said the child was "a fat baby" with a healthy appetite, playing vigorously with older children, growing out of her clothes and dying of sepsis, inflammation stemming from infection, that enveloped her like a flash flood ... The defense also criticized the autopsy in the case while the prosecutor said the medical examiner was incorrect in saying in March 2008 that sepsis was a cause of Ava Worthington's death ... After Mygrant said in his closing argument that Young was... (Longview Daily News, WA)
Strep B Seems to Trick Immune System Jul 15, 2009
Finding could lead to better treatment of sepsis, meningitis in newborns ... MONDAY, July 13 (HealthDay News) -- A bacterial pathogen that causes sepsis and meningitis in newborns shuts down immune cell function to ensure its survival, a new study shows. (MEDLINEplus)
Abortion pill used in1 in 4 U.S. terminations Jul 9, 2009
Since approval in 2000, there have been six deaths from sepsis, a bloodstream infection, among the more than 1. 1 million American women who have used Mifeprex, most recently one in July 2007. (MSNBC -- Health)
Report on Ky. player death: Coach followed rules Jul 2, 2009
The doctor concluded that an illness would have made Max more susceptible to heat stroke, but with no autopsy, the cause of his sepsis was more difficult to confirm. An attorney for Gilpin's mother, Todd Thompson, said the conclusions were not a surprise because the school system has from the beginning sought to exonerate itself and the coaches in the teen's death. (MSNBC -- Sports)
Coach followed rules Jul 2, 2009
The doctor concluded that an illness would have made Max more susceptible to heat stroke, but with no autopsy, the cause of his sepsis was more difficult to confirm. Gilpin's parents have sued Stinson, five assistant coaches and school administrators in a case set for trial in January. (Prep Sports Sports -- Rivals.com)
Advanced Sepsis Detection And Management System Created Jul 1, 2009
ScienceDaily (June 30, 2009) When Jason Martin gives a talk about his research, he begins with the dramatic story of Mariana Bridi da Costa: The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and feet failed to stop its spread ... They have developed and begun testing what they believe is the first real-time system for sepsis detection ... This summer, they will add an automated decision support system designed to guide attending physicians... (Science Daily)
3rd Circuit Recognizes New Cause of Action for Civil Rights Violations at Nursing Homes Jul 1, 2009
-operated nursing home as a result of neglect, malnourishment and bed sores that were so severe they led to a fatal case of sepsis. But a dissenting judge complained that the court was stretching the law too far and ignoring the U.S. Supreme Court's explicit warnings not to recognize new causes of action unless it was clear and unambiguous that Congress intended to create such a right. (Law.com)
Manslaughter trial opens for Oregon faith-healing couple Jun 30, 2009
He and fellow defense lawyer Mark Cogan said Ava was overwhelmed by a fast-acting infection called sepsis. Neidig said the cyst-like growths are common in the Worthington side of the family. (Longview Daily News, WA)
Artificial Liver For Drug Tests Jun 26, 2009
25, 2007) Changing the way that critically ill patients suffering from sepsis or multiple organ failure are fed could reduce liver dysfunction. A large study published in the journal Critical Care recommends. (Science Daily)
Area hospitals see mixed grades on yearly report card Jun 24, 2009
Postoperative Sepsis, a serious infection of the bloodstream that can occur after surgery was listed for Columbia Memorial as a lower rating than the state average. Those most susceptible to sepsis are those with weakened immune systems due to age or medication, and only 7 of the 194 hospitals listed in the table had an above average rating on the condition ... In the hospital records, they reference 2 cases out of approximately 4,000 surgical procedures, with their 2009 data currently at zero... (Catskill Daily Mail, NY)
A Pet's Bite Can Pass on MRSA Jun 24, 2009
Sepsis, a potentially fatal bloodstream infection, can be a complication following bite wounds from a pet infected with MRSA, as well as a number of other types of bacteria, the team noted. "Bite injuries are a major cause of injury in the USA and Europe each year, particularly in children. Bites to the hands, forearms, neck and head have the potential for the highest morbidity," the study authors concluded. (MEDLINEplus)
Study: MRSA may be transmitted by pet's bite Jun 23, 2009
Sepsis, a bloodstream infection, can be a severe complication of bite wounds infected with MRSA and a number of other types of bacteria, the researchers noted. Increasing prevalence of community-acquired MRSA in humans has been accompanied by MRSA colonization in domestic animals such as dogs, cats and horses. (Xinhuanet, China)
MRSA risk from dog and cat bites Jun 22, 2009
Sepsis can be a complication. Easily spread. (BBC News -- Health)
Novel Discovery In Dendritic Cell Signalling Pathways Pave The Way For New Therapeutic Targets Jun 21, 2009
"These findings have identified novel potential targets for the development of therapeutics against diseases that are involved with the CD14-NFAT pathway. For example, overexpression of CD14 has been associated with sepsis and chronic heart failure. New drugs that can modulate the CD14-NFAT pathway could provide treatments for such serious medical conditions.". Said Prof Philippe Kourilsky, Chairman of SIgN, "Prof Castagnoli has been contributing greatly to the area of dendritic cell regulation... (Science Daily)
WNY hospitals get average grades Jun 21, 2009
Millard Fillmore Gates for postoperative sepsis. Sisters of Charity and WCA for accidental puncture and laceration. (Buffalo Business First, NY)
Therapy Helps Improve Outcomes For Patients With Severe Sepsis Jun 19, 2009
ScienceDaily (June 18, 2009) A preliminary study suggests that a therapy for severe sepsis or septic shock that included the use of an antibiotic-based "hemoperfusion" device to remove toxic products of bacteria from the blood in addition to conventional treatment resulted in a reduced risk of death and appeared to improve blood circulation and reduce organ dysfunction, according to a new report ... Severe sepsis and septic shock are common problems in the intensive care unit and carry a high... (Science Daily)
Group B Strep Screening Guidelines Sparing Newborns Jun 19, 2009
GBS can cause sepsis, meningitis and pneumonia in infants, usually within the first week of life. If a pregnant woman is a carrier, the infection can be passed to her child during delivery. (MEDLINEplus)
