FDA Requires Additional Data For Seroquel XR Supplemental New Drug ... Dec 26, 2008
FDA Requires Additional Data For Seroquel XR Supplemental New Drug Application (Medical News Today)
Memory Pharmaceuticals Initiates Biomarker Study of R3487/MEM 3454 in Schizophrenia Dec 25, 2008
MONTVALE, N.J., Dec. 24 /PRNewswire-FirstCall/ -- Memory Pharmaceuticals Corp. (Nasdaq: ) today announced that it has dosed the first patient in its Phase 2 clinical study of the effect of R3487/MEM 3454, a nicotinic alpha-7 partial agonist, on electrophysiological biomarkers in patients with schizophrenia. The study will evaluate the effect of four doses of R3487/MEM 3454 on electrophysiological biomarkers (such as P50 sensory gating) that have been shown to be closely associated with... (PR Newswire)
Boys found beaten in park 'extremely critical' Dec 25, 2008
"Of the mentally ill people most likely to be dangerous, people with schizophrenia are at the top of the food chain," Pitt said. "Of that subset of . . . people that are violent, it's much more common for mentally ill to perpetrate violence on family members than it is upon strangers.". (AZCentral -- News)
FDA hesitates to relabel Seroquel Dec 25, 2008
It is currently used to treat people with schizophrenia or bipolar disorder ... Sales of Abilify, prescribed for bipolar disorder and schizophrenia, rose 34 percent to $564 million last quarter, helped by U.S. approval in May to market the drug for long-term use by children and teenagers ... Seroquel is currently used to treat people with schizophrenia or bipolar disorder. (The News Journal)
Details of man's life emerge after death (3290) Dec 25, 2008
He eventually joined the Navy, but was discharged as his schizophrenia began to emerge ... Things just got very hard for him after that, and he struggled with schizophrenia all his life. (Missoulian, MT)
Motor nerve targeting to limb muscles is controlled by ephrin proteins Dec 25, 2008
"The study of the ephrin proteins should help us understand diseases such as autism, schizophrenia as well as a number of neurological disorders," says Dr. Rmi Quirion, a scientific director at the Canadian Institutes of Health Research (CIHR). "We are proud to support this important study and hope it will help to improve the lives of people with these health problems.". (EurekAlert!)
Deaths prompt facility shutdown Dec 23, 2008
She also suffered from mild personality disorder, schizophrenia and the autoimmune disease Gillian-Barr Syndrome. Reports show that she died of sepsis, Melissa Livezey, spokeswoman for the Upper Moreland police, said. (Springfield Sun, PA)
New Insights Into Autism, Obsessive Behavior: Decreased Levels Of Binding Gene Affect Memory And Behavior Dec 23, 2008
"These studies may offer insight into the molecular underpinnings of repetitive behaviors such as those seen in autism spectrum disorder, obsessive compulsive disorder, schizophrenia and other neurodegenerative disorders," said Hamilton. "Because these studies involved interrupting the mTOR signaling after birth, they challenge the idea that some aspects of these conditions are developmentally predetermined.". (Science Daily)
Man who slit dads throat acquitted on insanity grounds Dec 23, 2008
I found the accused to be suffering from paranoid schizophrenia, she said, adding that it was the most dangerous form of schizophrenia ... When cross-examined, Dr Rabaiah told the court that ganja (marijuana) was not widely thought to cause schizophrenia although it could trigger that. (The Star Online, Malaysia -- News)
Youngest often most vulnerable to toxic air Dec 22, 2008
They'll look for new ways to prevent and treat major diseases, such as obesity, asthma, diabetes, autism, schizophrenia and injuries, which together cost the country $758 billion a year, according to the NIH.. Congress, which already has given $230 million to the project, will have to renew the study's funding each year, study director Peter Scheidt says. (USA Today)
Possible Genetic Causes Of Borderline Personality Disorder Identified Dec 21, 2008
20, 2008) According to the National Institute of Mental Health, borderline personality disorder (BPD) is more common than schizophrenia or bipolar disorder and is estimated to affect 2 percent of the population. In a new study, a University of Missouri researcher and Dutch team of research collaborators found that genetic material on chromosome nine was linked to BPD features, a disorder characterized by pervasive instability in moods, interpersonal relationships, self-image and behavior, and... (Science Daily)
Retired Martin County detective shares 35 years of memories Dec 21, 2008
After a psychiatrist gave the girl a preliminary diagnosis of either childhood schizophrenia or autism , Pakonis and child protection investigators concluded that there was no case for child abuse. Weeks later, a social worker found the girl naked and tied to a board, her face and one knee bloody and most of her body covered with bruises and cuts. (The Palm Beach Post)
Chromosomal changes seen in long-term pilots Dec 20, 2008
This can lead to a range of medical problems, such as leukemia, breast cancer, schizophrenia or muscular dystrophy, depending on were the fragments reattach. advertisement. (MSNBC -- Health)
NOWHERE TO TURN: Homeless advocates say more and more elderly New Orleanians, faced with few options, are holing up in abandoned buildings Dec 19, 2008
But the group is in poor health: Among their problems are liver and kidney disease, heart problems, paranoia, schizophrenia, HIV and AIDS, and dementia, said UNITY head Martha Kegel, who said donations of furniture and houseware are desperately needed to properly outfit Green and some of the other estimated 400 homeless people UNITY has housed this year with the help of federal rental assistance. For the homeless, fire is an ever-present threat, Green said. (Nola.com -- Sports)
Man who allegedly murdered 2 ruled unfit for trial again Dec 19, 2008
Rodney Aviles, 30, was on the brink of being released from the state mental hospital in May 2006 after doctors determined that he was no longer of danger to himself or others so long as he took medication to control his schizophrenia. His family learned about his impending freedom from a newspaper reporter, and Maricopa County Attorney Andrew Thomas immediately obtained a warrant for his arrest and charged him again for the two murders. (AZCentral -- News)
Autism And Schizophrenia Share Common Origin, Review Suggests Dec 19, 2008
18, 2008) Schizophrenia and autism probably share a common origin, hypothesises Dutch researcher Annemie Ploeger following an extensive literature study ... Developmental psychologist Annemie Ploeger has investigated whether there is a connection between disorders in the first month of pregnancy and the development of schizophrenia and autism ... The same error that occurs very early in pregnancy develops into autism in one individual and schizophrenia in another. (Science Daily)
Medicaid cuts could mean support center closure Dec 19, 2008
One of my friends once told me, "You can't catch my schizophrenia by shaking my hand.". Thanks for your time. (Burley South Idaho Press, ID)
BC police crack down on robberies of seniors Dec 19, 2008
Imagine one quick cut after another in which senior citizens, some suffering from Parkinson's disease or schizophrenia, some of whom need walkers or canes to stand or who are visually impaired, are seen being beaten and robbed on the street. The elderly victims are clubbed to the ground and left with broken ribs, fractured ankles, broken hips and bleeding head wounds, while the thieves frantically paw through their pockets before running off with whatever they can find. (Globe and Mail)
Vanda Pharmaceuticals cuts half its staff Dec 19, 2008
In an effort to stay operational through May, when it receives word on its second attempt at federal approval for its schizophrenia drug, Vanda Pharmaceuticals (NASDAQ: VNDA) has cut its formerly 53-person work force by more than half ... While it s suffering the same fate as fellow biotechs starved for cash in a down economy, Vanda has been particularly hard hit by the Food and Drug Administration s rejection of iloperidone, its schizophrenia candidate, in July. (Washington Business Journal, DC)
Texas Sues Drug Company For Millions Dec 18, 2008
AUSTIN -- A drug company supplied phony advocacy groups, trumped-up scientific claims and used Texas mental health officials as pitchmen so a top-dollar schizophrenia drug would get on the state's Medicaid list, a lawsuit filed by Texas officials alleges ... A drug company supplied phoney advocacy groups and used Texas mental health officials as "pitchmen"-- all so the firm's top-dollar schizophrenia drug would get on the state's Medicaid list, according to a newspaper report. (Click2Houston, TX)
Behind the science of fingerprints Dec 18, 2008
The methodology is commonly used to diagnose some types of mental retardation, schizophrenia, cleft palate and even heart disease. A more recent trend is to look for the genetic basis of certain psychological disorders or characteristics by studying the dermatoglyphics of the hand, and even more recently, finger digit ratios. (Jakarta Post, Indonesia -- Features)
Work gyms and performance Dec 18, 2008
Information on mental health including where to get help, how to look after a child or loved one with mental health problems and real stories of psychosis and schizophrenia. Find out how physical activity can add years to your life and life to your years. (NHS Choices)
Artist fights stigma of schizophrenia Dec 17, 2008
One of the pieces of work by Amber Christian Osterhout of Corinth, who created it to raise awareness in response to her brother's diagnosis of schizophrenia ... Two of the posters made by Amber Christian Osterhout, of Corinth, who created the work to raise awareness in response to her brother's diagnosis of schizophrenia ... Six months after his return home, Josh was diagnosed with schizophrenia, a biological brain disorder that affects one in 100 people, according to Irene Levine, professor of... (Albany Times Union)
New Mechanism For Attentional Control In The Human Brain Discovered Dec 17, 2008
The UC Davis study also provides new insights into the workings of a stimulant-like drug that could have broad applications for enhancing the cognition of people with conditions ranging from autism to schizophrenia ... "Now that we know how it works, we can develop better cognitive enhancers that can treat more people suffering from a wider variety of neurodevelopmental disorders, like ADHD, autism and schizophrenia," he said ... 4, 2000) A new brain imaging study from the Institute of... (Science Daily)
Siblings Of Mentally Disabled Face Own Lifelong Challenges, According To Researchers Dec 17, 2008
People with schizophrenia are more likely to suffer from ruptured appendix than others, according to new. (Mar. (Science Daily)
Filing alleges drug maker defrauded Texas to get on Medicaid list Dec 17, 2008
AUSTIN A major pharmaceutical firm funneled kickbacks to Texas health officials, distributed false marketing materials and deployed phony advocacy groups to get its top-dollar schizophrenia drug prescribed to low-income Texans, the state alleges in a new filing in a major fraud lawsuit ... In the early 1990s, drug companies began developing new, expensive schizophrenia drugs, and marketing them as more effective replacements for the generic drugs that had been around since the 1960s. (KHOU.com, TX)
Aging brains allow negative memories to fade Dec 17, 2008
Florin Dolcos received funding for the study through a postdoctoral fellowship from the Natural Sciences and Engineering Research Council of Canada, an award from the Canadian Psychiatric Research Foundation, and a Young Investigator Award from the U.S.-based National Alliance for Research on Schizophrenia and Depression. Roberto Cabeza received his funding from the U.S. National Institutes of Health. (EurekAlert!)
Number of attempted suicides on the rise Dec 16, 2008
A majority of what we have seen is personality disorders, such as manic depressive or paranoid schizophrenia. I don t know that we see a lot of trigger mechanisms that do that, Phillips said. (Rensselaer Republican, IN)
Pad Out Your Amazon Wish List Dec 16, 2008
In the touching and troubling , Patrick Tracey recounts how schizophrenia has tormented his family, afflicting two sisters, an uncle, a grandmother (who had a dentist yank out all of her teeth, hoping it would silence the voices in her head), and a great-great-grandmother. To find out why the Irish are perceived to be particularly vulnerable to insanity, Tracey travels to his ancestral home of Ireland. (Slate)
Younger Dad May Mean Healthier Child Dec 16, 2008
Some illnesses, such as schizophrenia, appear to be more common the older parents get ... Published in Oxford Journals Schizophrenia Bulletin, the study builds on Dr. Weisers previous research on parental age, autism and IQ scores. (Newsmax)
A monument to business Dec 15, 2008
" Third generation For a few years, Patrice was unable to go to work at Southside Monument. In 1997, their oldest son, Robert, committed suicide just shy of his 17th birthday. "He suddenly developed schizophrenia," she explained. "He was normal all his life. " The medications seemed to work for only a little while and then Robert's schizophrenic symptoms would return, she said. It is a mystery because no one else in the family tree had schizophrenia. "When he died, it just hit so hard. (The Augusta Chronicle)
Why Are Some People More Susceptible To Depression Than Others? Stressed-out Mice Reveal Role Of Epigenetics In Behavior Dec 15, 2008
This work opens promising leads for further exploration, because evidence of epigenetic modification has been observed in animal models of depression, addiction, schizophrenia and neuro-developmental disorders. Some psychoactive drugs like cocaine or anti-psychotics also cause changes in some of the co-factors involved in this genetic regulatory system. (Science Daily)
Charity reviews fundraising strategies as donations wane Dec 14, 2008
The Schizophrenia Society of Canada has run into similar problems ... Chris Summerville, the society's CEO, said the stigma surrounding schizophrenia complicates fundraising in the best of times, and now, competition for funding has become increasingly fierce. (Globe and Mail -- National)
Mother Of Man Shot By Officer Speaks To KFOX Dec 14, 2008
"The bullet is still in his stomach, Velasquez said.While Velasquez accepts the fact that her son broke the law, she said the cutting of the officer and the shooting of her son could have been avoided"Efrain has schizophrenia, and I told the policeman outside, Velasquez said. Velasquez said the police officers did not heed her warnings of her son's mental illness. (KFOXTV.com, TX)
Bettie Page, 85 Dec 13, 2008
She was arrested after an altercation with her landlady, and doctors who examined her determined she had acute schizophrenia. She spent 20 months in a state mental hospital in San Bernardino. (Globe and Mail)
Canvas: Exploring normal Dec 13, 2008
Spoken by the 10-year-old son of a woman suffering from schizophrenia, this question is filled with sadness, confusion and not a little frustration ... The child of a parent with schizophrenia, Greco drew from his own family history for his debut feature ... Equally admirable is Greco's determination not to sensationalize the subject of schizophrenia. (Toronto Star)
Senior Subjects: Hows your brain? Dec 12, 2008
These abnormal brain rhythms, says Llins, help account for a variety of serious disorders, including Parkinson s, schizophrenia, tinnitus and depression, so he wasn t surprised to discover that tinnitus was the problem in this case ... Among the interesting brain-related discoveries is one reported in the BBC News early in November, in which scientists say they may have found why people with schizophrenia have abnormal electrical waves in their brains ... Stone said, It s some of the first... (Lincoln Journal, MA)
Palm Pilots Bridge Communication Gap Between Therapists And Patients Dec 12, 2008
According to the National Institute of Mental Health, BPD is more common than schizophrenia or bipolar disorder and is estimated to affect 2 percent of the population. It is characterized by pervasive instability in moods, interpersonal relationships, self-image and behavior, and can lead to suicidal behavior, substance abuse and failed relationships. (Science Daily)
Value health-care workers with Dec 12, 2008
In a gang-controlled inner-city neighborhood, Terry stops to check on a client with schizophrenia. But as he is parking, two young armed men attempt to carjack the vehicle, forcing the worker to speed away. (NJ.com -- Times)
Sarcasm signals dementia Dec 12, 2008
"It can be very difficult to diagnose in early stages and to separate from depression or, later on, schizophrenia or personality disorders," Hodges said. The sarcasm test could replace some more expensive and less widely available tests for dementia, he said. (iAfrica.com)
Lexicon's Drug Candidate LX6171 for Cognitive Disorders Completes Phase 2A Clinical Trial Dec 12, 2008
However, the target of LX6171 continues to be intriguing, as this pathway has recently been associated with schizophrenia in human genetic studies ... We will evaluate interest from third parties in the compound and its target for other neurobehavioral indications where the target may be relevant, such as schizophrenia. (Primezone Releases)
Leeds ordered to facility Dec 11, 2008
Lee Leeds family has said that he suffers from paranoid schizophrenia. His primary attorney, Senior Deputy Public Defender Robert Ikola, has said that Leeds has been refusing to take his medication. (Santa Maria Times)
ACLU alleges rights abuses Dec 10, 2008
A 27-year-old Liberian national, diagnosed with schizophrenia, bounced among three county jails with a skin condition and dental problems that were left untreated for months. Some mental health issues were ignored as well, the report found. (Boston Globe)
Alexza's AZ-004 (Staccato(R) Loxapine) Meets Primary Endpoint of Treating Acute Agitation in Patients with Bipolar Disorder in Phase 3 Trial Dec 10, 2008
AZ-004 is an inhalation product candidate being developed for the acute treatment of agitation in patients with schizophrenia or bipolar disorder ... Acute agitation affects many people suffering from major psychiatric disorders, including schizophrenia and bipolar disorder ... Based on the Company's analysis of patient information from the National Institute of Mental Health (NIMH), the company believes that in the United States schizophrenia afflicts about 2. (PR Newswire)
AstraZeneca Drug Did Not Meet Trial Criteria Dec 9, 2008
LONDON -- AstraZeneca said Tuesday that its AZD3480 drug did not meet the criteria for statistical significance on the primary outcome endpoints in its Phase IIb study in cognitive dysfunction in schizophrenia. AstraZeneca and its partner Targacept said they didn't expect to progress the drug into Phase III studies for CDS. AstraZeneca said a decision over potential further development of AZD3480 in Alzheimer's disease or attention deficit/hyperactivity disorder is now expected in the first half... (Fox News)
Targacept drug fails in trial Dec 9, 2008
An announcement from the Winston-Salem-based biotech Targacept said because of the test results the two companies do not plan to advance the drug, known as TC-1734, into further trials in relation to cognitive dysfunction in schizophrenia. In September, Targacept and AstraZeneca announced that the same drug produced inconclusive results in clinical trials in Alzheimer s disease patients. (Business Journal of the Greater Triad Area)
Timeline of Carpenter's hospitalizations Dec 8, 2008
Carpenter was involuntarily admitted to Mesa Vista, where he was diagnosed as having a chronic paranoid schizophrenia ... July 11, 2005: Carpenter was discharged from Mesa Vista and sent to the Alpine treatment center, diagnosed with paranoid schizophrenia, impulse control disorder, marijuana abuse and personality disorder ... Aug. 31, 2006: A Patton State Hospital Wellness and Recovery Team concluded that Carpenter was competent to stand trial after being treated for schizophrenia. (San Diego Union-Tribune)
Shortstop contrite in his farewellFormer top pick Greene says he 'let the team down' Dec 7, 2008
Kahlil stated that "It wasn't as if I had in mind: 'I'm not coming back to San Diego; I'm going to play the (next two) years, then go. Both Towers and Aldersen spun that Greene would be leaving for free agency after next year, so the trade was merely recouping value since he was basically gone anyway. When I read comments like Kahlil's and Trevor's that characterize a willingness to work it out only to be stonewalled by management, it makes me believe that something is rotten in the state... (San Diego Union-Tribune -- Sports)
Poor Children's Brains Like Stroke Victims' Dec 6, 2008
5, 2004) Overactivity of protein kinase C (PKC), an enzyme that is implicated in bipolar disorder and schizophrenia, markedly impairs higher brain functions in animals, according to a Yale study published. (Sep. (Science Daily)
Farmington native publishes first novel Dec 6, 2008
In short Hollywood pitch parlance, the book s plot may be summarized as follows: Think A Beautiful Mind and replace literature for mathematics and manic depression for schizophrenia. Then add the TV show Quantum Leap. (Park Hills Daily Journal, MO)
Cannabis 'affecting young minds' Dec 6, 2008
" She said virtually all of the research on both short and longer-term cognitive effects has been conducted on adults. This is a problem as the young, developing brain could be much more vulnerable to its effects, she explained. There is evidence that cannabis not only worsens existing mental health problems but may trigger some conditions Martin BarnesDrugScope chief executive Ms Herts said studies show young people who use cannabis regularly or heavily are at least twice as likely to develop a... (Yahoo News -- Substance Use)
VA coming to Leeward side Dec 6, 2008
"We're seeing a steady increase of people with post-traumatic stress disorder, psychological traumas and schizophrenia in the ones who are coming back already," he said. "And then if they have additional physical or amputee problems, they are going to need a lot more care and counseling.Fred Dodge, a veteran, retired physician and longtime resident of the Wai'anae Coast, had no word of the new clinic. But, he said, "I'm sure there is a need for it. (Honolulu Advertiser)
Why Do the Mentally Ill Die Younger? Dec 6, 2008
People with depression or bipolar disorder are about twice as likely to be obese as the general population; in people with schizophrenia, that likelihood is three times greater ... According to Mental Heath America, based in Virginia, a recent survey of people with schizophrenia revealed that they rarely discussed physical health with their psychiatrists. (Time.com)
Most Newer Antipsychotics No Better Than Older Ones, Just Different Dec 6, 2008
Saturday, December 6, 2008. People need to find the one that works best for them, experts say. (U.S. News & World Report)
Review: Micheal Greenberg's Hurry D... Dec 5, 2008
Greenberg reads about other writers who've had to deal with familial madness, particularly James Joyce and the extent to which he went to assuage his own daughter's schizophrenia, desperately seeking an epiphany. He analyzes his own behavior and that of his family, sometimes no-holds barred. (Suite101.com)
Psychiatric drugs force queried Dec 5, 2008
Most had been diagnosed with schizophrenia, bipolar disorder or another psychotic illness. The practice seemed more common in the UK but that is probably because mechanical restraint is used more often in other countries to stop patients harming themselves and others. (BBC News -- Health)
Coerced Medication Used In Psychiatric Care Despite Lack Of Clinical Evidence Dec 5, 2008
The review, published in the latest Journal of Advanced Nursing, suggests that patients receiving coerced medication (CM) are more likely to be in their thirties with a diagnosis of schizophrenia, bipolar disorder or another psychotic disorder ... 23, 2006) This researcher looked at several studies and found no evidence that schizophrenia without medication resulted in long-term harm for patients. (Science Daily)
New Hope For Treatment Of Brain-damaging Disorder In Children Dec 5, 2008
10, 2007) Puberty may have an impact on areas of the brain that contribute to bipolar disorder or schizophrenia in youth, according to a new. (Oct. (Science Daily)
Murder suspect found incompetent Dec 4, 2008
Judge James Rigali suspended criminal proceedings in the case against Lee Leeds, 32, and ordered that the man described by his family as suffering from paranoid schizophrenia be forced to take psychotropic drugs. Advertisement. (Lompoc Record, CA)
Concern over mentally ill inmates Dec 4, 2008
The most common mental health problems among prisoners were found to be schizophrenia and bi-polar affective disorder. Dr McLellan pointed to a "greater reliance on medication than would be desirable" and the use of segregation cells - despite some inmates claiming this can make mental health problems worse. (BBC News -- UK)
Memory Pharmaceuticals Receives NASDAQ Decisions Dec 4, 2008
Memory Pharmaceuticals Corp., a biopharmaceutical company, is focused on developing innovative drugs for the treatment of debilitating CNS disorders, many of which exhibit significant impairment of memory and other cognitive functions, including Alzheimer's disease and schizophrenia. For additional information, please visit our website at. (PR Newswire)
Stephen Bobb, 49, gentle dog lover, hard worker Dec 4, 2008
In his late teens, Mr. Bobb was diagnosed with schizophrenia, a severe and disabling mental disorder. He took medication but his illness wasn t always under control, said his brother-in-law, Jack Mobley of Douglasville. (Atlanta Journal-Constitution)
Murder suspect unfit for trial Dec 4, 2008
Judge James Rigali suspended criminal proceedings in the case against Lee Leeds, 32, and ordered that the man described by his family as suffering from paranoid schizophrenia be forced to take psychotropic drugs. Leeds primary attorney, Senior Deputy Public Defender Robert Ikola, said outside court that his client has been refusing to take his medicine. (Santa Maria Times)
Teens: Just moody, or mentally ill? Dec 3, 2008
He was hearing voices calling his name when no one was around experiencing what he later learned were the first symptoms of schizophrenia and was too frightened to confide in anyone, even his mother ... While schizophrenia is relatively rare, affecting only about 1 percent of the population and usually developing during the college years, depression is common among younger teens. (MSNBC -- Health)
Mental hospital deemed unsafe Dec 3, 2008
Security camera footage also showed employees falsified records indicating the restrained patient, a 24-year- old man with schizophrenia, was being constantly monitored when he was not, according to the 131-page report. In little more than a year, all four of North Carolina's remaining state-run mental hospitals have now either lost or been threatened with losing accreditation because of patient deaths or incidents of abuse and neglect. (News & Observer)
