Rotavirus Infections Decline More than 70 Percent in Children in U.S. Oct 26, 2008
Quest Diagnostics Health Trends(TM) Report shows declines vary widely by state MADISON, N.J., Oct. 25 /PRNewswire-FirstCall/ -- The largest study of rotavirus laboratory data developed since an oral rotavirus vaccine was introduced in the U.S. in early 2006 shows that cases of rotavirus infection have decreased significantly, suggesting the vaccine is preventing infection in infants and young children. The latest Quest Diagnostics Health Trends(TM) Report also provides evidence for the first... (PR Newswire)
FDA APPROVES ROTARIX(R) [Rotavirus Vaccine, live, oral], THE FIRST VACCINE LICENSED TO COMPLETE THE ROTAVIRUS IMMUNIZATION SERIES BY FOUR MONTHS OF AGE Apr 4, 2008
Specifically, significant protection was demonstrated against severe rotavirus gastroenteritis during two rotavirus seasons caused by types G1 (96%), G2 (86%), G3 (94%), G4 (95%), and G9 (85%), the most commonly circulating rotavirus types in the U.S. "Studies have shown that naturally occurring rotavirus infection protects against subsequent moderate to severe rotavirus gastroenteritis regardless of the infecting serotype," David I. Bernstein, M.D., M.A., Director, Infectious Diseases; Gamble... (PR Newswire)
FDA Advisory Committee Recommends US Approval of Rotavirus Vaccine Feb 21, 2008
Ready access to good medical care means that children in industrialized countries rarely die from rotavirus infection ... Because vaccination is the only way to prevent hospitalizations from severe rotavirus infection in industrialized countries and the mortality it causes in low-resource settings, the World Health Organization (WHO) strongly recommends the inclusion of rotavirus vaccination into the national immunization programs of countries where clinical trials have shown rotavirus vaccines... (PR Newswire)
Pneumonia deaths seen with Glaxo vaccine: FDA Feb 18, 2008
The review comes ahead of a U.S. Food and Drug Administration advisory meeting on Wednesday to consider approval of the oral vaccine, which aims to prevent rotavirus infection, a cause of severe infant diarrhea that requires hospitalization. The virus is a major killer of children in developing countries, but deaths in the United States are rare. (Reuters)
New Data Published in The Lancet Show GSK's ROTARIX(R) Offers Protection Against the Most Common Circulating Rotavirus Types Nov 24, 2007
"The candidate vaccine contains a live, weakened form of natural human rotavirus derived from the most common human rotavirus strain with the goal of offering protection against the most commonly circulating and emerging rotavirus serotypes by mimicking the protective effects of natural human rotavirus infection," said David I. Bernstein, MD, MA, Director, Infectious Diseases; Gamble Program at Cincinnati Children's Hospital Medical Center ... The vaccine is designed to prevent rotavirus... (PR Newswire)
New Approach To Improving Diarrhea In Infants With Probiotics Oct 1, 2007
In comparison, only 7 percent of mice escaped rotavirus infection without prophylactic intervention. The other five probiotic bacteria strains tested were either less efficacious preventives or were not at all effective. (Science Daily)
Soy isoflavone may inhibit common gastrointestinal illness in infants Sep 7, 2007
The soy isoflavone genistin--at concentrations present in soy infant formula-- may reduce a babys susceptibility to rotavirus infections by as much as 74 percent, according to a University of Illinois study published in Septembers Journal of Nutrition ... Its exciting to think that the isoflavones in soy formula could be a cost-effective nutritional approach to decreasing the incidence and severity of rotavirus infections, especially among children in developing countries who are most at... (EurekAlert!)
* Center for Disease Control warns of flu season peak Jan 15, 2007
Localized outbreaks of rotavirus infections have also dogged the nation over the past few weeks. "Rotavirus is a threat wherever people are concentrated in an enclosed space, such as in nursing homes," Shih said. (Taipei Times, Taiwan -- World)
