Treatment success for overactive bladder with urinary urge incontinence refractory to oral antimuscarinics: a review of published evidence Nov 21, 2009
Treatment options for overactive bladder (OAB) with urinary urge incontinence (UUI) refractory to oral antimuscarinics include: botulinum toxin type A (BoNTA), sacral neuromodulation (SNM), and augmentation cystoplasty (AC). A standard treatment success metric that can be used in both clinical and economic evaluations of the above interventions has not emerged. (BioMed Central)
P&G finalizes drug biz sale Nov 1, 2009
The sale includes P&G s (NYSE: PG) osteoporosis drug Actonel a $1 billion brand as well as other drugs; the co-promotion rights to overactive bladder treatment Enablex; and P&G s prescription drug pipeline and manufacturing facilities. P&G on Oct. 28 said the sale will give it a one-time earnings boost of 43 cents per share in the second fiscal quarter, though the final gain amount will be provided in January. (Dayton Business Journal, OH)
P&G finalizes drug biz sale Oct 31, 2009
The sale includes P&G s osteoporosis drug Actonel a $1 billion brand as well as other drugs; the co-promotion rights to overactive bladder treatment Enablex; and P&G s prescription drug pipeline and manufacturing facilities. P&G on Oct. 28 said the sale will give it a one-time earnings boost of 43 cents per share in the second fiscal quarter, though the final gain amount will be provided in January. (Cincinnati Business Courier, OH)
Bladder Problems May Often Be Related to Mental Health Oct 27, 2009
FRIDAY, Oct. 23 (HealthDay News) -- Psychiatric disorders and sexual trauma in women increase the risk of lower urinary tract symptoms, such as incontinence and overactive bladder, a new study finds. U.S. researchers analyzed the answers in two questionnaires -- the Urogenital Distress Inventory-6 and Incontinence Impact Questionnaire-7 -- completed by 121 female veterans referred to a specialized urology clinic for evaluation of lower urinary tract symptoms. (MEDLINEplus)
Psychiatric disorders and sexual trauma are associated with lower urinary tract symptoms Oct 20, 2009
New York, NY, October 20, 2009 Depression, anxiety disorders and sexual trauma have all been implicated as risk factors in lower urinary tract symptoms (LUTS) such as incontinence and overactive bladder. The exact nature of these associations is unknown. (EurekAlert!)
North Lewis Needs to Catch It's Head Oct 10, 2009
DI Reader wrote on Oct 9, 2009 8:38 AM:" A friend of mine has a child at North Lewis and from what I hear the bathroom breaks are pathetic. The teacher literally times them. They have 3 minutes from the time they get in the stall to do their business. She has had to get a doctors excuse because her child has overactive bladder syndrome and the teacher was constantly giving her demerits for going to the restroom too often. As a person with this same condition I can say it is no fun to hold it! ".... (New Iberia, LA)
Allergan Sues FDA over Ban on Off-Label Marketing of Botox Oct 3, 2009
Allergan is currently testing Botox for several conditions that are now considered off-label, including chronic migraines and overactive bladder. "We're not seeking to diminish the FDA's authority," Ingram says. (BusinessWeek)
P&G cleared to sell drug business Oct 1, 2009
The sale includes Cincinnati-based P&G s osteoporosis drug Actonel a $1 billion brand as well as other drugs; the co-promotion rights to overactive bladder treatment Enablex; and P&G s prescription drug pipeline and manufacturing facilities. P&G bases its pharmaceutical business in Mason, Canada and Western Europe, and operates plants in Germany and Puerto Rico. (Columbus Business First, OH)
A matter of urgency Sep 30, 2009
An overactive bladder is a common affliction which affects both men and women of all ages. PATIENTS with an overactive bladder (OAB) often wrongly assume that it is a normal part of ageing ... In Malaysia and Japan, there is a high prevalence of OAB in men and the condition is getting more common with age, says Dr Tubaro who gave a media presentation on The Urgent Need To Treat Overactive Bladder. (The Star Online, Malaysia)
Bladder Problems Sep 22, 2009
Urge incontinence often results from overactive bladder. Overactive bladder results when the muscle surrounding the bladder spasms ... With an overactive bladder, the muscle spasms with no relation to the amount of urine in the bladder, and the need to urinate may occur when the bladder is not full. (Suite101.com)
REGURIN(R) XL (trospium chloride) Once Daily Tablets Now Available in the UK for the Treatment of Overactive Bladder Sep 8, 2009
LONDON, September 7 /PRNewswire/ -- Regurin(R) XL (trospium chloride), a once-daily, prolonged-release capsule to treat patients with overactive bladder (OAB) has been launched in the UK. Regurin(R) XL provides rapid, significant and consistent improvements in the symptoms of OAB1 and has a reduced potential for central nervous system (CNS) side effects(2-7) ... "Overactive bladder has a significant, and often underestimated, impact on the quality of life of all patients. In elderly dependent... (PR Newswire)
Envive, Inc. to Exhibit at CEDIA EXPO 2009, September 10th-13th, 2009 at Booth 2862 Sep 5, 2009
Get Info On Treatment ement Tips For Overactive Bladder. Be Smart- First Get a 100% Free, Instant Credit Report Right Now. (Yahoo! Wire -- Entertainment News)
Remember Unforgettable Moments by Turning the Pages of Life... -- Poetic Anthology Traces Life Through Literary Masterpieces Sep 4, 2009
Get Info On Treatment ement Tips For Overactive Bladder. With GE Capital Corporation. (Primezone Releases)
Endo Pharmaceuticals to Present at Thomas Weisel Partners Healthcare Conference 2009 Sep 1, 2009
Endo Pharmaceuticals is a specialty pharmaceutical company engaged in the research, development, sale and marketing of branded and generic prescription pharmaceuticals used to treat and manage pain, overactive bladder, prostate cancer and the early onset of puberty in children, or central precocious puberty (CPP). Its products include LIDODERM((R)), a topical patch to relieve the pain of postherpetic neuralgia; Percocet((R)) and Percodan((R)) tablets for the relief of moderate-to-moderately... (PR Newswire)
Prelim Capital Announces 2-For-1 Stock Split Aug 29, 2009
Get Info On Treatment ement Tips For Overactive Bladder. Personalized term life insurance quotes to fit your budget. (CCNMatthews Press Releases)
Warner Chilcott Buying P&G Drug Business for $3.1B Aug 25, 2009
The company also gets a colitis drug called Asacol with about $600 million in annual sales, a patent through 2014 and an extended release version just launching, plus Didronel for Paget's disease and other bone disorders and Enablex for overactive bladder. The deal is expected to close by year-end. (ABC News -- Wire)
Warner Chilcott to Buy P&G Unit for $3 Billion: Sources Aug 24, 2009
Pescription drugs include osteoporosis treatment Actonel and overactive bladder treatment Enablex. Pd Goldman Sachs in February to help sell its prescription brands or find other ways to exit the business, sources told Reuters at the time. (ABC News -- Wire)
10 biggest sleep problems: How to fix them Aug 22, 2009
In women, frequent urination can go hand in hand with urinary issues such as , an overactive bladder, urinary tract infections, or cystitis ... Urinary tract problems, such as an overactive bladder, can be helped with Kegel exercises. (Atlanta Journal-Constitution -- Health)
Bladder cells feel stretch Aug 7, 2009
Dr. Sokabe said, "This is the first report to show that TRPV4 is a primal stretch-detector in urothelial cells. Given that TRPV4 is critically involved in the sensing mechanism in the bladder, development of chemicals modulating TRPV4 activity may be useful for treatment of bladder disorders such as overactive bladder and pollakiuria.". . (EurekAlert!)
Supernus Pharmaceuticals raises $35M Jul 29, 2009
In April 2008, the privately held company borrowed against its royalty payments from two marketed products that use its original technology, Oracea, an oral prescription treatment for inflammatory lesions, and Sanctura XR, a treatment for an overactive bladder, to raise $75 million. This is non-dilutive, said Rip Wilson, Supernus chief financial officer. (Washington Business Journal, DC)
United Football League Signs GameWear Team Sports As Official Uniform Supplier Jul 28, 2009
Get Info On Treatment ement Tips For Overactive Bladder. Free 3-bureau Credit Report includes Transunion, Equifax, Experian. (Yahoo! Wire -- Entertainment News)
FDA Releases List of Potential Drug Risks Jun 6, 2009
Pfizer's overactive bladder drug Detrol is being investigated in connection with reports of Stevens-Johnson syndrome, a serious skin reaction, the FDA said. The problems are potential safety issues and their appearance on the list "does not mean that FDA has identified a causal relationship" with the drug, the agency said. (Newsmax)
Endo Announces Compensation for New CFO Alan Levin May 30, 2009
Endo Pharmaceuticals is a specialty pharmaceutical company engaged in the research, development, sale and marketing of branded and generic prescription pharmaceuticals used to treat and manage pain, overactive bladder, prostate cancer and the early onset of puberty in children, or central precocious puberty (CPP). Its products include LIDODERM(R), a topical patch to relieve the pain of postherpetic neuralgia; PERCOCET(R) and PERCODAN(R) tablets for the relief of moderate-to-moderately severe... (PR Newswire)
McAllister: Bladder control problems are treatable May 28, 2009
Urge incontinence, also known as overactive bladder, is caused by urinary muscle spasms that lead to the uncontrolled loss of urine. In many cases, individuals who suffer from an overactive bladder experience strong, unexpected urges to void, especially after drinking liquids or hearing the sound of running water. (Green Valley News & Sun, AZ)
NURSE’S NOTES - Incontinence can be treated May 27, 2009
Urge incontinence: An overwhelming urge to void resulting in urine leakage, typically caused by an overactive bladder or hormone irregularities. Mixed incontinence: Concurrent stress and urge incontinence symptoms. (Missoulian, MT)
JCH hosts diabetes support group May 15, 2009
Many men and women suffer from urinary urgency, also called overactive bladder or small bladder, which can be treated or cured, as can pelvic and/or bladder pain. Symptoms of nerve damage in the urinary tract can be embarrassing and hard to discuss because of the nature of the problem. (Taylor Daily Press, TX)
Meditate Your Way To Better Bladder Health May 10, 2009
LUHS physicians enrolled Raisor in a clinical trial using cognitive therapy to manage her overactive bladder ... Patients were eligible to participate in this study, if they had a diagnosis of overactive bladder (OAB), which is the sudden and unstoppable need to urinate. (Science Daily)
Gel Effective for Women with Overactive Bladder May 6, 2009
CHICAGO (Reuters Health) - Applying a gel containing the anti-spasmodic agent oxybutynin to the skin is safe and effective for women with overactive bladder, according to a study reported here at the annual meeting of the American Urological Association. Overactive bladder can be disabling and is associated with a marked decrease in health-related quality of life as well as higher rates of depression, Dr. Roger Dmochowski noted ... The gel, which goes by the brand name Gelnique, is applied "once... (MEDLINEplus)
Electrical Implant Might Help With Bladder Control Apr 17, 2009
There are few treatments that can claim to cure people with overactive bladders or urinary retention, said lead author G. Peter Herbison, from the Dunedin School of Medicine in New Zealand ... Overall, the results showed benefits primarily for patients with symptoms of overactive bladder and with no known obstruction who had failed other methods of treatment. (Science Daily)
GUMC researcher creates first Web-interactive CME course for physicians on pharmaceutical marketing Apr 1, 2009
Another compelling example demonstrating the influence of pharmaceutical marketing is a list of diseases and conditions the course says were created by the pharmaceutical industry such as GERD, erectile dysfunction, excessive sleepiness, restless legs syndrome, overactive bladder syndrome, social anxiety disorder and osteopenia. The authors explain, "We associate these conditions with a specific drug because the companies that made each of these drugs invented or renamed the condition. In... (EurekAlert! -- Business News)
Endo Pharmaceuticals Appoints Dr. Nancy Hutson to Board of Directors Apr 1, 2009
Its products include LIDODERM(R), a topical patch to relieve the pain of postherpetic neuralgia; PERCOCET(R) and PERCODAN(R) tablets for the relief of moderate-to-moderately severe pain; FROVA(R) tablets for the acute treatment of migraine attacks with or without aura in adults; OPANA(R) tablets for the relief of moderate-to-severe acute pain where the use of an opioid is appropriate; OPANA(R) ER tablets for the relief of moderate-to-severe pain in patients requiring continuous, around-the-clock... (PR Newswire)
Does Detrol have negative impact on memory? Mar 20, 2009
Both my sister and I have been complaining about memory problems since we started taking it for overactive bladder problems. I phoned my doctor s office about this issue and was told they have never heard about this reaction at all. (Atlanta Journal-Constitution -- Health)
Dynogen seeks bankruptcy protection Feb 26, 2009
The company had been trying to develop drugs to treat irritable bowel syndrome, overactive bladder disorder, and nocturnal gastroesophageal reflux disease (often associated with heartburn). A year ago, Dynogen said it would merge with Apex Bioventures Acquisition Corp. of Hillsborough, Calif. (Boston Globe)
Many Clinical Trials Moving Overseas Feb 20, 2009
And whether overseas trials even test drugs that are needed in those countries is also a question, the study authors said, citing, for example, that drugs for overactive bladder and fibromyalgia are being developed in countries where diseases like malaria and tuberculosis are prevalent. "There's a huge benefit to research being conducted in the U.S.," Schulman said. (MEDLINEplus)
Bed-wettingblues: Adultssuffer, too Feb 19, 2009
e., primary enuresis) or a secondary condition thats developed in adulthood due to a neurological disorder, prostate obstruction, diabetes, overactive bladder, complications from childbirth or other medical issues. But some believe that number is low. (MSNBC -- Health)
BETTER LIFE: More on sexual health Feb 11, 2009
If you know the location of every restroom on your route to work, you might have an overactive bladder, as do as many as 17% of your fellow Americans ... In rats with overactive bladders, researchers found that a part of the brain normally activated only when the bladder is full was activated all of the time, throwing the forebrain, which controls higher brain functions, into disarray, New Scientist ... That might explain why an overactive bladder so disrupts quality of life, one scientist says.... (USA Today -- Life)
Ketamine Abuse Damages Bladder, Kidneys Feb 7, 2009
On further testing, 47 patients were found to have overactive bladder or decreased bladder elasticity, the team reports. Damage to one or both kidneys was seen on ultrasound in 30 patients, and four of them had areas of dead kidney tissue. (MEDLINEplus)
Drug Adherence Poor in Women with Urinary Trouble Feb 7, 2009
Because of the high discontinuation rates of anticholinergic therapy for lower urinary tract symptoms, health care providers "must be vigilant" regarding alternative forms of treatment, such as bladder training and pelvic floor rehabilitation, for overactive bladder "and increase our awareness that this group of women is being treated inadequately," the investigators conclude. SOURCE: Obstetrics and Gynecology, December 2008. (MEDLINEplus)
Researchers Suspect Novel Gene Is Causing Restless Legs Syndrome In A Large Family Feb 7, 2009
17, 2008) Persistent imminent orgasms in women are associated with restless legs and overactive bladder. Scientists studied 18 Dutch women with Persistent Sexual Arousal Syndrome. (Science Daily)
