MU research team establishes family tree for cattle, other ruminants Oct 20, 2009
"This also provides us an opportunity to identify animal models for human disease since, for example, an excess amount of intramuscular fat in humans is associated with insulin resistance and type 2 diabetes," Taylor said. We're all interested in reconstructing our ancestry. (EurekAlert!)
Age-old woes, new tactic Oct 19, 2009
Sirtris is reporting that one of its drugs, SRT501, had lowered blood glucose levels and insulin resistance in human trials. The science has gone extremely well, said Guarente, who is a scientific adviser to Sirtris. (Boston Globe)
Insulin Resistance and Weight Loss ... Oct 17, 2009
Insulin Resistance and Weight Loss Help. Insulin Resistance and Weight Loss Help ... Weight loss help - how modifying diet, certain medication and exercise can combat insulin resistance for those struggling to control weight or lose excess fat. (Suite101.com)
Should Parents of Obese Kids Lose Custody? Oct 17, 2009
Overweight children can also develop insulin resistance, hypertension, high cholesterol, sleep apnea and orthopedic problems and go into early puberty. "Children are vulnerable. If they're given food and told to finish what's on the plate, they'll eat it, and without exercise get bigger and bigger," says Tam Fry, chairman of Britain's Child Growth Foundation, who is lobbying obesity experts to consider overnutrition a form of child abuse. (Time.com)
A whey protein supplement decreases post-prandial glycemia Oct 16, 2009
Incidence of diabetes, obesity and insulin resistance are associated with high glycemic load diets. Identifying food components that decrease post-prandial glycemia may be beneficial for developing low glycemic foods and supplements. (Nutrition Journal)
The food-energy cellular connection revealed Oct 16, 2009
"Shift workers face a 100 percent increase in the risk for obesity and its consequences, such as high blood pressure, insulin resistance and an increased risk of heart attacks," says Howard Hughes Medical Investigator Ronald M. Evans, Ph. D., a professor in the Salk Institute's Gene Expression Laboratory. (EurekAlert!)
Healthy Neighborhoods May Be Associated With Lower Diabetes Risk Oct 14, 2009
11, 2009) Short sleep times, experienced by many individuals in Westernized societies, may contribute to the development of insulin resistance and reduced glucose tolerance, which in turn may increase the. . (Science Daily)
Most H1N1 Patients With Respiratory Failure Treated With Oxygenating System Survive Illness Oct 14, 2009
Researchers describe how both peripheral insulin resistance and primary beta-cell. (Oct. (Science Daily)
Antioxidants May Raise Diabetes Risk Oct 8, 2009
They found mice that lacked the enzyme were less likely to develop insulin resistance -- an early sign of diabetes -- than normal mice ... "Our work suggests that antioxidants may contribute to early development of insulin resistance, a key pathological hallmark of type 2 diabetes," Tiganis said. (MEDLINEplus)
Could Antioxidants Make Us More, Not Less, Prone To Diabetes? Study Says Yes Oct 8, 2009
In fact, there is considerable scientific evidence that chronic ROS production within cells can contribute to human diseases, including insulin resistance and type 2 diabetes ... "Our studies indicate that 'physiological' low levels of ROS may promote the insulin response and attenuate insulin resistance early in the progression of type 2 diabetes, prior to overt obesity and hyperglycemia," said Tony Tiganis of Monash University in Australia ... "In the case of early type 2 diabetes and the... (Science Daily)
High-fat Diet Impairs Muscle Health Before Impacting Function Oct 6, 2009
The researchers found the high-fat diet resulted in insulin resistance, large increases in fat mass and weight gain ... The role of this decreased function in relation to insulin resistance and type 2. (Science Daily)
Metabolic syndrome linked to liver disease in obese teenaged boys Sep 30, 2009
It is defined by insulin resistance, increased waist circumference, high blood pressure, and abnormal measures of high density lipoprotein ("good cholesterol") and triglycerides in the blood. The criteria are similar for pediatric metabolic syndrome, although there is some dispute over details of the definition. (EurekAlert!)
Its Autumn. . . Sep 26, 2009
They have been ranked as the vegetable highest in nutritional value and, despite the name sweet, it has been shown to stabilize blood sugar levels and lower insulin resistance, a boon for diabetics. To start off the fall season, here are some great-tasting recipes for sweet potatoes. (Bogalusa Daily News, LA)
Childbearing Increases Chance Of Developing The Metabolic Syndrome Sep 24, 2009
23, 2009) Childbearing is associated directly with future development of the metabolic syndrome - abdominal obesity, high triglycerides, insulin resistance and other cardiovascular disease risk factors - and for women who have had gestational diabetes, the risk is more than twice greater, according to a study co-authored by University of Alabama at Birmingham (UAB) researchers published in the American Journal of Obstetrics and Gynecology. See also. (Science Daily)
Obese kids with big bellies at greatest heart risk Sep 24, 2009
Obese children with waists bigger than 90 percent of their peers had lower "good" HDL cholesterol, higher harmful triglyceride levels, and greater insulin resistance a risk factor for type 2 diabetes compared to obese kids with smaller waists, researchers found. This "tells us they are at more risk for heart problems later on in life," Dr. Reda Bassali of the Medical College of Georgia in Augusta told Reuters Health. (MSNBC -- Health)
American Heart Association Meeting Report: High-Sugar Diet Increases Men's Blood Pressure; Gout Drug Protective Sep 24, 2009
Men in both groups had an increase in fasting triglycerides and an indication of insulin resistance by a method called homeostatic model assessment (HOMA), while on the increased fructose diet. The HOMA method is used to quantify insulin resistance and beta-cell function ... "When you give fructose to animals, they absolutely develop every feature of metabolic syndrome: they get abdominal fat, high triglycerides, low HDL, their blood pressure goes up and they get insulin resistance," Johnson... (PR Newswire)
Chew on This Sep 24, 2009
Obese children with waists bigger than 90 percent of their peers had lower "good" HDL cholesterol, higher harmful triglyceride levels, and greater insulin resistance, , researchers found. Smart Fitness. (MSNBC -- Health)
What You Need to Know About Beer Bellies Sep 22, 2009
People with excess belly fat have a tendency to develop nasty conditions such as insulin resistance, diabetes, high blood pressure, heart disease, and high cholesterol over and above the already increased risk a person receives from other forms of obesity. How Much Belly Fat is Too Much. (Fox News)
Arena Pharmaceuticals Reports Positive, Highly Significant BLOSSOM Trial Results for Weight Management; NDA Submission on Track for December Sep 18, 2009
Arena is also studying several key secondary endpoints, including changes in serum lipids, markers of inflammation and insulin resistance, and in the BLOOM-DM trial, other indicators of glycemic control. About the FDA Draft Guidance. (PR Newswire)
Active Older Adults Live Longer, Have Better Functional Status Sep 17, 2009
29, 2009) Sedentary, obese older adults appear to improve their functional abilities and reduce insulin resistance through a combination of resistance and aerobic exercises, according to a new. (Apr. (Science Daily)
SHBG and Risk of Type 2 Diabetes in Women and Men Sep 17, 2009
Background Circulating sex hormone binding globulin levels are inversely associated with insulin resistance, but whether these levels can predict the risk of developing type 2 diabetes is uncertain. Methods We performed a nested case control study of postmenopausal women in the Women's Health Study who were not using hormone therapy (359 with newly diagnosed type 2 diabetes and 359 controls). (New England Journal of Medicine)
Discovery May Pave Way to Better Diabetes Care (HealthDay) Sep 13, 2009
Discovery May Pave Way to Better Diabetes Care - Yahoo. Search Type Choose a search type from the items below. (Yahoo News -- Politics)
University of Hawaii at Manoa CRCH scientists report adulthood body size associated with cancer risk Sep 12, 2009
Excess fat is associated with a number of conditions that contribute to cancer development including low-grade chronic inflammation, insulin resistance, metabolic abnormalities, and hormone imbalances. These conditions may in turn contribute to more aggressive prostate malignancies. (EurekAlert!)
Size of fat cells and waist size predict type 2 diabetes in women Sep 11, 2009
The disease begins as insulin resistance, and as the need for insulin rises, the pancreas gradually loses its ability to produce insulin. Type 2 diabetes often is associated with older age, but is increasingly being diagnosed in children. (EurekAlert!)
Metabolic Syndrome May Raise Risk of Peripheral Artery Disease Sep 10, 2009
Using data on more than 27,000 women taking part in the Women's Health Study, researchers identified participants with metabolic syndrome, a collection of symptoms including abdominal obesity, high blood pressure, low HDL ("good") cholesterol, high triglyceride levels and insulin resistance. Women were considered to have metabolic syndrome if they had three or more of those symptoms. (Atlanta Journal-Constitution -- Health)
Breaking the cycle of obesity Sep 9, 2009
The children born to thinner moms also appeared to be healthier overall, with lower insulin resistance and cholesterol levels, signs of a reduced risk of diabetes and heart disease. And these results were the same when the researchers limited their analysis to children who were siblings: 25 of the 49 moms had children born both before and after their surgeries. (MSNBC -- Health)
Add coconut, cut fat Sep 9, 2009
A diet rich in coconut oil keeps fat away and also protects against insulin resistance, a new study shows ... Obesity and insulin resistance are major factors leading to the development of Type 2 diabetes ... Insulin resistance is an impaired ability of cells to respond to insulin. (India Times, India)
Will Metformin Cause Gastrointestin... Sep 9, 2009
If you can make it through these first few uncomfortable weeks, Metformin can help reduce the risk of developing type 2 diabetes, increase fertility and help women with PCOS and/or insulin resistance lose weight ... It has also proven helpful in resolving insulin resistance and preventing the onset of diabetes in women with PCOS. For these reasons, any woman who is struggling with diarrhea or gastrointestinal problems related to Metformin should carefully weigh the pros and cons of discontinuing... (Suite101.com)
The origin of diabetes: Don't blame your genes Sep 8, 2009
Juleen Zierath and her colleagues at the Karolinska Institute in Stockholm, Sweden, are trying to find out how people develop insulin resistance, the underlying cause of type 2 diabetes ... But people with insulin resistance and thus the late-onset version of the disease do produce insulin ... They took muscle biopsies from 17 healthy people, 17 people with type 2 diabetes and eight people with early signs of insulin resistance, so-called pre-diabetics. (The Economist)
Blueberry Drink Protects Mice From Obesity, Diabetes Sep 6, 2009
The blood glucose levels of lab mice, which were genetically predisposed to obesity, insulin resistance, diabetes and hypertension, fell by 35 percent after three days of drinking the super juice. "These mice were an excellent model that closely resembles obesity and obesity-linked type 2 diabetes in humans," Haddad added. (Atlanta Journal-Constitution -- Health)
Can Thunder Thighs Help Heart Health? Sep 6, 2009
Some studies have reported that insulin resistance may be provoked in the leg muscle, and that low levels of subcutaneous fat in the thighs leads to adverse glucose and lipid, or fat, metabolism. But some researchers are not convinced about this potential mechanism. (ABC News)
People With Type 2 Diabetes Not Meeting Important Nutritional Recommendations Sep 6, 2009
6, 2007) Consumption of sugar-sweetened drinks, not including 100 percent fruit juice, may be associated with insulin resistance, even in otherwise healthy adults, according to nutritional. (Mar. (Science Daily)
Exercise Minimizes Weight Regain By Reducing Appetite And Burning Fat First, Carbs Later Sep 5, 2009
6, 2008) Exercise decreases everyone's insulin resistance and therefore reduces the chances of developing diseases such as type 2 diabetes. This study shows that even a single bout of exercise helps obese. (Science Daily)
Do High-fat Diets Make Us Stupid And Lazy? Sep 5, 2009
The results will be important not only in informing athletes of the best diets to help their training routine, but also in developing ideal diets for patients with metabolic disorders such as diabetes, insulin resistance or obesity ... (July 14, 2008) One of the characteristics of type 2 diabetes is insulin resistance, which refers to the inability of cells in the body to respond appropriately to the hormone insulin. (Science Daily)
Health Watch: Stress-busting massage tips Sep 4, 2009
Washington University School of Medicine in St. Louis researchers found that fatty liver disease can be a sign of metabolic problems such as insulin resistance, which affects the body's ability to metabolize sugar. People with fatty livers also have increased levels of triglycerides, a risk factor for heart attack and stroke. (Belmont Citizen Herald, MA)
Scientists Turn Off 'Obesity Switch' in Mice Sep 4, 2009
Obesity is associated with chronic, low-grade inflammation that can lead to insulin resistance, a precursor to type 2 diabetes. Not only did the mice with the deleted IKKE gene avoid weight gain, they showed no signs of chronic inflammation, fatty liver or insulin resistance either, according to the study. (Atlanta Journal-Constitution -- Health)
Mice Can Eat 'Junk' And Not Get Fat: Gene Found Sep 4, 2009
Obesity is associated with a state of chronic, low-grade inflammation that leads to insulin resistance, which is usually the first step in the development of Type 2 diabetes. In the Cell paper, Saltiel and his colleagues show that deleting, or "knocking out," the IKKE gene not only protected high-fat-diet mice from obesity, it prevented chronic inflammation, a fatty liver and insulin resistance, as well ... It is thought that one reason over eating causes insulin resistance is that fat is... (Science Daily)
Weight-Loss Surgery Breaks Families' 'Obesity Cycle' Sep 4, 2009
Obesity is on the rise and can lead to insulin resistance, cardiovascular disease and pregnancy complications ... The younger siblings also had improved cardiovascular markers, including reduced insulin resistance and lower cholesterol, the researchers found. (MEDLINEplus)
Nonagenarian Researcher Petitions FDA To Ban Trans Fats Sep 4, 2009
(July 9, 2008) Dietary research in rats suggests that trans-fats do not increase the risk of insulin resistance and diabetes, which may ease at least one area of health concern for these. (Feb. (Science Daily)
Biotransformed Blueberry Juice Fights Fat And Diabetes Sep 3, 2009
The scientists tested the effect of biotransformed blueberry juice on a group of mice prone to obesity, insulin resistance, diabetes and hypertension. Incorporating biotransformed blueberry juice into the water of mice reduced their food intake and their body weight. (Science Daily)
Weight-loss surgery can break "obesity cycle": study Sep 3, 2009
The younger siblings also had improved cardiovascular markers, including reduced insulin resistance and lower cholesterol, the researchers found. The study findings show the importance of the intrauterine environment, which seems to trump even genes and the environment in which the child is raised, the researchers noted. (Xinhuanet, China)
Weight-loss Surgery Can Break A Family's Cycle Of Obesity Sep 2, 2009
Obesity can lead to insulin resistance, cardiovascular disease and pregnancy complications and is a major contributor to causes of death in industrialized nations ... Furthermore, children born after their mother's weight-loss surgery had improved cardiovascular markers including reduced insulin resistance and lower cholesterol. (Science Daily)
PCOS, Insulin Resistance And Depres... Aug 31, 2009
PCOS, Insulin Resistance And Depression. PCOS, Insulin Resistance And Depression ... Insulin Resistance May Cause Depression In Women With PCOS. (Suite101.com)
Scientists find turnoff for fat gene Aug 29, 2009
In doing so, fatostatin influences many of the genes involved in fat production and various aspects of metabolic syndrome -- a collection of risk factors including obesity, high cholesterol and insulin resistance. Studies in cell culture showed that fatostatin significantly lowered the activity of 63 genes, including 34 directly associated with fatty acid or cholesterol synthesis. (Xinhuanet, China)
Molecular Link Found Between Insulin Resistance And Inflammation Aug 28, 2009
27, 2009) An exploration of the molecular links between insulin resistance and inflammation may have revealed a novel target for diabetes treatment, say scientists at the John G. Rangos Sr. Research Center, Children's Hospital of Pittsburgh of UPMC. Their findings were published earlier this month in the online version of Diabetes, one of the journals of the American Diabetes Association ... "But it's not yet clear if there is a cause-and-effect relationship between chronic exposure to low-grade... (Science Daily)
Prostate cancer hormone drugs risky for some Aug 26, 2009
The drugs can increase insulin resistance and raise cholesterol. They increase fat, too. (MSNBC -- Health)
Testosterone Therapy May Help Men with Heart Failure Aug 26, 2009
"This study confirms our previous finding for a beneficial effect of testosterone in men with moderate chronic heart failure, improving functional exercise capacity and insulin resistance," said Dr. T. Hugh Jones, a consultant endocrinologist at the University of Sheffield in England. Jones and his colleagues have reported two studies with positive results, one using testosterone injections, the other using a hormone-delivering skin patch. (MEDLINEplus)
Fat In The Liver -- Not The Belly -- May Be A Better Marker For Disease Risk Aug 26, 2009
The researchers report online in the journal Proceedings of the National Academy of Sciences (Early Edition) that when fat collects in the liver, people experience serious metabolic problems such as insulin resistance, which affects the body's ability to metabolize sugar ... 6, 2009) Where different ethnic groups store fat in their bodies may account for differences in the likelihood they'll develop insulin resistance and non-alcoholic fatty liver disease, researchers have. (Science Daily)
JNCI news brief: High serum insulin levels and risk of prostate cancer Aug 22, 2009
and colleagues investigated the relationship of the level of serum insulin and glucose, as well as surrogate indices of insulin resistance, to the development of prostate cancer. Researchers conducted a prospective casecohort study nested within a cancer prevention study of Finnish men (100 case subjects with prostate cancer and 400 non-case subjects without prostate cancer). (EurekAlert!)
Maybe Your BMI Doesn't Really Matter Aug 19, 2009
Lear argued that "BMI is flawed because changes in BMI may be attributable to changes in skeletal muscle rather than body fat, whereas WC changes are attributable entirely to changes in abdominal fat." It matters because central body fat is positively associated with insulin resistance, part of diabetes. Another option is waist-hip ratio. (Click2Houston, TX)
He changes often, but not for the better Aug 19, 2009
Replacement nicotine gum is better for her health than smoking, but it s not intended for long-term use, which has been associated with insulin resistance, severe allergic reactions, and possible cardiovascular problems. If your wife is having cigarette cravings and plans to use it temporarily, she should be OK. Please don t be afraid to express your concerns to her. (Boston Globe)
Grapefruit Diet Held the Key to Fighting Obesity Aug 14, 2009
The researchers found that the naringenin corrected elevations in tryclycerides and cholesterol, prevented the onset of insulin resistance, and otherwise normalized the metabolism of insulin. Also, the naringenin completely reprogrammed the livers of the mice so that excess fat was burned rather than stored. (Newsmax)
Food Stamp Use Linked To Weight Gain, Study Finds Aug 13, 2009
17, 2005) Fast-food consumption has strong positive associations with weight gain and insulin resistance, suggesting that fast food increases the risk of obesity and type 2 diabetes, conclude authors of a US ... 19, 2005) Researchers have shown a correlation between fast food, weight gain, and insulin resistance in what appears to be the first long-term study on this subject. (Science Daily)
Insufficient sleep may be linked to increased diabetes risk Aug 11, 2009
Short sleep times, experienced by many individuals in Westernized societies, may contribute to the development of insulin resistance and reduced glucose tolerance, which in turn may increase the long-term risk of diabetes, according to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology olism (JCEM) ... The article, "Exposure to recurrent sleep restriction in the setting of high caloric intake and physical inactivity results in increased insulin... (EurekAlert!)
Sedentary Lives Can Be Deadly: Physical Inactivity Poses Greatest Health Risk To Americans, Expert Says Aug 11, 2009
10, 2009) Short sleep times, experienced by many individuals in Westernized societies, may contribute to the development of insulin resistance and reduced glucose tolerance, which in turn may increase the. (June 3, 2006) Many of the detrimental effects of physical inactivity can be reversed, and in some cases improved, by a similar period of moderate. (Science Daily)
Evotec Announces Strong Second Quarter Financial Results Aug 7, 2009
The royalty income from DeveloGen was a result of the upfront payment DeveloGen received in its collaboration with Boehringer Ingelheim (published on May 13, 2009) on a target addressing insulin resistance. The target formed part of the Joint Venture between Evotec and DeveloGen which ended in 2005. (Primezone Releases)
Insufficient sleep ups diabetes risk Aug 4, 2009
Short sleep times may contribute to the development of insulin resistance and reduced glucose tolerance, which in turn may elevate the risk of diabetes, concludes a new study ... Short sleep times may contribute to the development of insulin resistance and reduced glucose tolerance, which in turn may elevate the risk of diabetes, concludes a new study. (India Times, India)
Acute effect of electroacupuncture at the Zusanli acupoints on decreasing insulin resistance as shown by lowering plasma free fatty acid levels in steroid-background male rats Aug 2, 2009
This study reports the use of a large dose of prednisolone to evaluate the effects of EA in a state of insulin resistance ... The SBRs were randomly divided into EA-treatment and non- EA treatment groups and 15-Hz EA was applied to the bilateral Zusanli acupoints to investigate its effects on insulin resistance ... Insulin resistance was successfully induced by a large dose of prednisolone in male rats. (BioMed Central)
Why You Can't Lose Weight Aug 1, 2009
However, there is strong evidence that something called insulin resistance is a contributor ... When a person develops insulin resistance, their body s ability to maintain ideal blood glucose levels is impaired ... Insulin resistance is common in overweight people. (Suite101.com)
M. D. Anderson study finds common diabetic therapy reduces risk of pancreatic cancer Aug 1, 2009
According to Li, more than 35 million prescriptions for the drug are filled annually, and it's most often given to type 2 diabetic patients who are obese and/or have insulin resistance. "Metformin works by increasing the cellular sensitivity to insulin and decreasing its level circulating in diabetics. Insulin also seems to have a growth-promoting effect in cancer," said Li, the study's senior author. (EurekAlert!)
Two Studies On Polycystic Ovarian Syndrome Shed Light On Its Causes And Its Effect On Brothers Of Women With The Condition Jul 31, 2009
In another study, researchers found that brothers of women with PCOS and insulin resistance are themselves at greater risk of developing insulin resistance or diabetes, suggesting that factors associated with the condition can be passed down to sons as well as daughters ... Prof Davies said: These findings suggest a new pathway for the development of PCOS. We think that factors associated with the pre-existence of cardiovascular dysfunction in the mother or the father, and which operate during... (Science Daily)
Modern Insanity: What Really Makes Us Crazy Jul 30, 2009
Search Type Choose a search type from the items below. More on Parenting ancy. (Yahoo News -- Technology)
Orientation scheduled for diabetes program Jul 27, 2009
Additional sessions will include monthly education regarding diabetes and prediabetes, relaxation methods, insulin resistance syndrome, fitness and carbohydrate counting. A group coaching/counseling session will also be held each month. (Mason City Globe-Gazette, IO)
Recognizing Obesity in Dogs & Cats ... Jul 27, 2009
These hormones also appear to play a key role in mediating inflammation, in appetite satiation (promoting meal termination) and satiety (regulating meal frequency), and in insulin resistance ... Obesity is one of the most common predisposing factors in insulin resistance and this is a result of the action of the adipokines produced in the fat cells of obese pets. (Suite101.com)
Mom's Diet Before Conception May Affect Baby Jul 23, 2009
Researchers found that the effects of nutrition, such as a high-fat diet and vitamin B and folate deficiencies, as well as diseases such as diabetes, during this time could trigger epigenetic changes that manifest in offspring as obesity, insulin resistance, and cardiovascular disease ... Researchers found that the effects of nutrition, such as a and vitamin B and folate deficiencies, as well as diseases such as diabetes, during this time could trigger epigenetic changes that manifest in... (ABC News)
