Bowel Disease Drugs Increase Cancer Risk Oct 20, 2009
LONDON (Reuters) - Some treatments for inflammatory bowel disease increase the risk of infection-related cancers, French scientists said on Monday, but the benefits of the drugs still outweigh the risks. Thiopurine drugs -- immunosuppressive medicines that inhibit the body's immune system -- are regularly used to treat inflammatory bowel disease, the researchers said, but can increase the risk of cancers linked to viral infections ... Laurent Beaugerie and colleagues at the Saint-Antoine... (MEDLINEplus)
Complications Are Not Best Predictor Of Hospital Mortality, Study Finds Oct 20, 2009
(June 18, 2008) Hospitals with higher annual volumes of patients with inflammatory bowel disease who undergo surgery have lower in-hospital mortality rates than hospitals with lower volumes of IBD patients. . (Science Daily)
Select 'Friendly' Bacteria Shape Immune System Oct 16, 2009
(June 2, 2008) A naturally occurring molecule made by symbiotic gut bacteria may offer a new type of treatment for inflammatory bowel disease, according to scientists at the California Institute of Technology. The. (Science Daily)
Triggers Found In Cells' Transition From Colitis To Cancer Oct 15, 2009
29, 2008) Individuals with the inflammatory bowel disease ulcerative colitis are at increased risk of developing colon cancer ... 18, 2007) New data generated in mice has provided support for the hypothesis that defects in the innate immune system might underlie some cases of inflammatory bowel disease -- a group of disorders. (Science Daily)
Discovery of genetic defect may lead to better treatments for common gut diseases Oct 9, 2009
New findings related to an uncommon genetic disorder may impact diagnosis and treatment of inflammatory bowel disease ... INDIANAPOLIS New findings related to an uncommon genetic disorder may impact the diagnosis and treatment of inflammatory bowel disease (IBD), the most common chronic gastrointestinal illness in children and teens ... "We now know that a genetic defect that selectively affects the production of oxidants inside of white blood cells can cause gastrointestinal symptoms of CGD.... (EurekAlert!)
Ulcerative Colitis Treatment Reduces Need For Surgery By Almost Half, Study Suggests Oct 2, 2009
Ulcerative colitis, an inflammatory bowel disease (IBD) that causes chronic inflammation of the colon, is characterized by abdominal pain and diarrhea ... 15, 2007) Mesalamine use among patients with inflammatory bowel disease was associated with a decrease in incidence of colorectal cancer when comparing cases and controls. (Science Daily)
Meridian to distribute GI disease test Oct 1, 2009
The test can differentiate between inflammatory bowel disease and the less serious irritable bowel syndrome by identifying a marker called calprotectin, Meridian said in a news release. The Buhlmann Calprotectin test fits very well in Meridian s gastroenteric product range, providing another key technology for our lab customers, Antonio Interno, president of Meridian Bioscience Europe, said in the release. (Cincinnati Business Courier, OH)
Drug Treats Ulcerative Colitis Sep 30, 2009
Ulcerative colitis, an inflammatory bowel disease (IBD) that causes chronic inflammation of the colon, is characterized by abdominal pain and diarrhea. Like Crohn's disease, another common IBD, ulcerative colitis can be debilitating and often lead to colectomy or surgical removal of the colon. (Newsmax)
Pitt researchers net $5 million from NIH to explore better ways to grow cells for regenerative medicine Sep 26, 2009
In 2007, Eva Szigethy, of the Children's Hospital of Pittsburgh of UPMC and an assistant professor of psychiatry and pediatrics at Pitt, received a New Innovators grant to use inflammatory bowel disease as a model for investigating the interactions between the brain, gut, and immune system in determining how adolescents cope with chronic illness. The following year, Barry London, a Pitt professor of medicine, was presented with a Pioneer Award to develop new techniques to image electrical... (EurekAlert!)
Does The Distance A Patient Has To Travel Affect Where They Choose To Get Their Care? Sep 15, 2009
(June 18, 2008) Hospitals with higher annual volumes of patients with inflammatory bowel disease who undergo surgery have lower in-hospital mortality rates than hospitals with lower volumes of IBD patients. (June 9, 2009) A set of expert consensus-based, quality-of-care indicators identified considerable variability in the quality of pancreatic cancer care among hospitals, and may be used to evaluate and identify. (Science Daily)
Metabolic Bone Disease In Cirrhosis Patients Sep 14, 2009
13, 2008) Researchers have found patients with inflammatory bowel disease or chronic liver disease were at increased risk of developing Vitamin D deficiencies. Two separate studies highlight the importance of. (Science Daily)
ASK DR. H: Screening guidelines change Sep 10, 2009
The following are clear risk factors for colon cancer: Age over 50; personal history of precancerous colon polyps; personal history of inflammatory bowel disease (i. e., ulcerative colitis and Crohns disease), but not irritable bowel syndrome; family history of colon cancer in parent or sibling; being African-American; being of Ashkenazi Jewish heritage; history of smoking; obesity; prior history of radiation to the abdomen; heavy chronic alcohol use; adult-onset diabetes; and a diet high in... (Atlanta Journal-Constitution -- Health)
Designing Probiotics That Ambush Gut Pathogens Sep 9, 2009
9, 2009) Bacteria in the human gut could produce substances that protect against colon cancer and provide therapy for inflammatory bowel disease. In the journal Microbiology, researchers report initial. (Science Daily)
Promising New Target Emerges For Autoimmune Diseases Sep 8, 2009
It is likely that this mechanism is involved in inflammatory bowel disease (IBD) and ulcerative colitis, Banerjee says. After examining the process further, Banerjee s team would like to apply the insights in animal studies. (Science Daily)
Vitamin C Deficiency Impairs Early Brain Development, Guinea Pig Study Finds Sep 5, 2009
4, 2009) New research at LIFE Faculty of Life Sciences at University of Copenhagen shows that vitamin C deficiency may impair the mental development of new-born babies. In the latest issue of the well-known scientific journal The American Journal of Clinical Nutrition, a group of researchers headed by professor Jens Lykkesfeldt shows that guinea pigs subjected to moderate vitamin C deficiency have 30 per cent less hippocampal neurones and markedly worse spatial memory than guinea pigs given a... (Science Daily)
High-dose Therapy For Liver Disease Not Effective, Study Suggests Sep 1, 2009
Approximately 70 percent of people with PSC have an associated disease such as inflammatory bowel disease, osteoporosis, gallbladder disease and bile duct cancer or cholangiocarcinoma. However, only 1 to 5 percent of people with inflammatory bowel disease have PSC. ... 7, 2004) T cells activated in the gut during inflammatory bowel disease can be re-routed to the liver and cause chronic liver disease, according to Eksteen and colleagues in the December 1 issue of The. (Science Daily)
Genetically Engineered Bacteria Are Sweet Success Against Inflammatory Bowel Disease Aug 22, 2009
The treatment is for bowel disorders such as inflammatory bowel disease, which affects one in 400 people in the UK and for which there is no cure ... In research to be published in Gut, the therapy has been proven to work in animals with colitis, one of the major forms of inflammatory bowel disease ... 24, 2007) People with inflammatory bowel disease may also be at risk for developing nerve damage and other neurological problems, according to recent. (Science Daily)
Scientists make "sugar bug" drug for bowel disease Aug 21, 2009
inflammatory bowel disease. tumor necrosis factor. (Yahoo News -- Technology)
Stomach Bugs May Boost Bowel Disease Risk Aug 15, 2009
NEW YORK (Reuters Health) - A bout of diarrheal disease caused by the stomach bugs Salmonella or Campylobacter increases the odds that a person will develop inflammatory bowel disease, with the risk persisting 15 years or more after infection ... Inflammatory bowel disease, or IBD, refers to a group of conditions, including Crohn's disease and ulcerative colitis, marked by chronic inflammation in the intestines, leading to symptoms like abdominal pain and diarrhea. (MEDLINEplus)
Pharmos Corporation Reports 2009 Second Quarter Results Aug 13, 2009
Various CB2-selective compounds from Pharmos' pipeline have completed preclinical studies targeting pain, multiple sclerosis, rheumatoid arthritis, inflammatory bowel disease and other disorders. These are available for licensing / partnering. (PR Newswire)
Budesonide is not beneficial for the treatment of diarrhea in metastatic melanoma patients Aug 12, 2009
Budesonide is currently used for the treatment of inflammatory bowel disease, asthma, non-infectious rhinitis and for the treatment and prevention of growths in the nasal cavity. . (EurekAlert!)
Zeria Pharmaceutical Agrees to Buy Switzerland's Tillotts for $128 Million Aug 4, 2009
Revenue in the global market for inflammatory bowel disease such as totals about 240 billion yen ($2. 5 billion) a year, , a Zeria spokesman, said by telephone from Tokyo. (Bloomberg -- Japan)
Colic In Babies May Be Caused By Gut Bacteria Jul 25, 2009
Inflammation in the gut of colicky infants closely compared to levels in patients with inflammatory bowel disease. Colic could prove to be a precursor to other gastrointestinal conditions such as irritable bowel syndrome, celiac disease and allergic gastroenteropathies. (Science Daily)
Healthy fat link to bowel disease Jul 24, 2009
A high intake of polyunsaturated fat in the diet, while good for the heart, may lead to inflammatory bowel disease, say researchers. Experts believe a high intake of linoleic acid, found in foods like "healthy" margarines, may be implicated in a third of ulcerative colitis cases. (BBC News -- Health)
C. Difficile Spores Spread Superbug Jul 22, 2009
29, 2007) Clostridium difficile infection is four times more likely to kill patients with inflammatory bowel disease. C difficile is an important cause of diarrhea among inpatients, and the numbers of new. (Science Daily)
Microscopic 'Beads' Could Help Create 'Designer' Immune Cells That Ignore Transplanted Organs Jul 17, 2009
Marked microparticles also have treatment potential in diseases where the immune system attacks normal tissue, such as arthritis, multiple sclerosis and inflammatory bowel disease, Dr. Horuzsko says. Conversely the method could be used to deliver a compound to block HLA-G activity, which also is heightened in tumors. (Science Daily)
Individuals At Risk For Developing Colon Cancer Identified Jul 15, 2009
29, 2008) Individuals with the inflammatory bowel disease ulcerative colitis are at increased risk of developing colon cancer. New data have identified a central role for the soluble factor TNF-alpha in the. (Science Daily)
Dough! NZ bakes in fear over folate Jul 14, 2009
Now two peer-reviewed US studies published this year have linked excessive folate in the human diet to higher rates of prostate cancer in men and inflammatory bowel disease in children. The findings have so concerned the British and Irish governments that they have put a hold on the introduction of their own mandatory fortification programs, and NZ wants to do the same. (Sydney Morning Herald -- Australia)
Novel Genetic Finding Offers New Avenue For Future Crohn's Disease Treatment Jul 13, 2009
ITCH, when malfunctioning, causes widespread inflammatory diseases, including inflammatory bowel disease, gastritis, uncontrolled skin inflammation, and pulmonary pneumonitis. See also. (Science Daily)
Small Bowel Obstruction: Diagnosis Jul 12, 2009
The patient may have a history of abdominal surgery (causes adhesions) or may have a hernia, inflammatory bowel disease, or gallstones (see Causes of Small Bowel Obstruction in the previous article). Vomiting may cause the patient to become dehydrated. (Suite101.com)
ChemoCentryx to Present at The 9th World Congress on Inflammation in Tokyo, Japan Jul 9, 2009
Dr. Schall's lecture titled, "Treating Inflammation by Inhibition of Chemokine Receptors: Practical Requirements and Efficacy of CCR9 Antagonism in Inflammatory Bowel Disease" will be given on Thursday, July 9, 2009 at 9:00 am local time. "It is a privilege to have been invited to speak at this prestigious gathering of thought leaders involved in the search for innovative treatments in inflammatory disease," said Thomas J. Schall, Ph. (PR Newswire)
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Inflammatory Bowel Disease. Bladder Health. (HealthScout)
Risk Of Tuberculosis From Arthritis Medication Examined Jul 3, 2009
(May 23, 2008) A new survey cautions physicians that drugs commonly prescribed for patients suffering from immunological disorders such as rheumatoid arthritis and inflammatory bowel disease may carry risks of. (July 17, 2008) Drugs that have helped treat millions of rheumatoid arthritis sufferers may hold the key to many more medical conditions, including atherosclerosis -- a leading cause of heart disease -- says the. (Science Daily)
Antibiotics Take Toll On Beneficial Microbes In Gut Jul 3, 2009
They could also aid in understanding and treating inflammatory bowel disease, which affects an estimated 500,000 to 1 million Americans, and Clostridium difficile, a growing and serious infection problem for hospitals ... The findings will guide Young in related work in which he is using mouse models to examine how changes in the microbiota in the gut may influence how inflammatory bowel disease develops and progresses ... 29, 2007) Clostridium difficile infection is four times more likely to... (Science Daily)
Kirby letter had it all Jun 29, 2009
THC and/or other cannabinoids have been prescribed in the treatment of spasticity and other neurogenic pain, as well as Glaucoma, Inflammatory Bowel Disease and multiple sclerosis. These, among several others for which THC has been prescribed, are serious, often life-altering medical conditions. (Logan Herald Journal, UT)
Roche Pulling Accutane Acne Medicine Off Market Following Jury Verdicts Jun 27, 2009
Some Accutane users allege the drugmaker failed to properly warn them the medicine could cause inflammatory bowel disease. The drug also has been linked to birth defects and depression. (Bloomberg -- US)
Anti-inflammatory drugs may defeat a treatment-resistant type of cancer Jun 25, 2009
The anti-inflammatory drugs etanercept and infliximab, which are currently used to treat arthritis and inflammatory bowel disease, work by suppressing TNF , suggesting a new way to curb the malignancy of this type of lymphoma. The team tested the idea in mice that had been injected with aggressive lymphoma cells and found that nascent tumors shrank in six days. (EurekAlert!)
* Is there Dignitas in needless death? Jun 24, 2009
But two had Crohns disease, an inflammatory bowel disease; two were tetraplegics; three had kidney disease, which can be usually treated by dialysis or a transplant and one had rheumatoid arthritis X all conditions that doctors say are not terminal. To go off and commit suicide simply on the basis of these conditions would be premature and unreasonable. (Taipei Times, Taiwan -- World Business)
Colorectal Cancer Increasing in You... Jun 24, 2009
Doctors do the screening only when the patient has a family history, chronic inflammatory bowel disease or a predisposing genetic condition. Since they don't screen most patients below 50, this gives the benign polyps time to turn into invasive cancer. (Suite101.com)
Suicide queue worries British health services Jun 23, 2009
But two had Crohn's disease, an inflammatory bowel disease; two were tetraplegics; three had kidney disease, which can be usually treated by dialysis or a transplant; and one had rheumatoid arthritis - all conditions which doctors say are not terminal. The details have prompted calls for the Britain to provide better end-of-life care and a renewed debate over demands for a new legal right of assisted death to render the growing British use of Dignitas unnecessary. (Sydney Morning Herald -- World)
Is Accutane to blame in girl's '07 killing? Jun 21, 2009
In addition, Roche Pharmaceuticals, the drug's manufacturer, has paid millions of dollars to patients who filed lawsuits after suffering inflammatory bowel disease while taking Accutane. Some advocates and researchers have blamed suicides on Accutane use, among them U.S. Rep. (Pittsburgh Post-Gazette, PA)
Study May Redefine How A Chronic Auto-immune Disease Is Diagnosed Jun 19, 2009
24, 2007) People with inflammatory bowel disease may also be at risk for developing nerve damage and other neurological problems, according to recent. (Sep. (Science Daily)
Powerful Nutrient Cocktail Can Put Kids With Crohn's Into Remission Jun 18, 2009
ScienceDaily (June 17, 2009) Treating children with inflammatory bowel disease (IBD) usually involves the same steroids-based medication prescribed to adults. But such treatments can have negative side effects for kids and teens dealing with IBD.. (Science Daily)
Teen diagnoses own disease in class Jun 16, 2009
Crohn's disease is often misdiagnosed or diagnosed very late, says Dr. Corey Siegel, director of the Inflammatory Bowel Disease Center at Dartmouth-Hitchcock Medical Center in Lebanon, New Hampshire. "Granulomas are oftentimes very hard to find and not always even present at all," Siegel said. (CNN -- Health)
Two Drugs Better Than One for Crohn's Patients Jun 5, 2009
"The use of monoclonal antibodies is rising for a number of gastroenterological disorders, such as inflammatory bowel disease," said Dr. Nicholas J. Shaheen, of the University of North Carolina School of Medicine, in the news release. "New indications for these treatments are continuing to be developed and the safety profile is better understood, making them good treatment options for patients with recurrent or chronic gastrointestinal diseases.". (MEDLINEplus)
Electronic Pill Shows Its Smarts By Measuring pH Levels In Digestive Tract Jun 5, 2009
"By using the SmartPill to measure the pH throughout the digestive tract, we were able to see how the pH levels can vary in patients with ulcerative colitis. This may help us understand why some drug treatments are more effective than others," says Dr. Brian Bosworth, lead investigator, assistant professor of medicine at Weill Cornell Medical College, and a Crohn's and colitis specialist at the Jill Roberts Center for Inflammatory Bowel Diseases at NewYork-Presbyterian Hospital/Weill Cornell... (Science Daily)
Enzyme Involved In Inflammatory Bowel Disease Discovered Jun 3, 2009
ScienceDaily (June 3, 2009) Researchers at Penn State College of Medicine, working with biochemists, geneticists and clinicians at the University of Bern, Switzerland and in the United Kingdom, have discovered an enzyme that has a key role in inflammatory bowel disease (IBD) ... 24, 2007) People with inflammatory bowel disease may also be at risk for developing nerve damage and other neurological problems, according to recent ... 26, 2006) Inflammatory bowel disease roughly doubles the chances... (Science Daily)
Environmental Pollution Increases Risk Of Liver Disease, Study Finds Jun 2, 2009
7, 2004) T cells activated in the gut during inflammatory bowel disease can be re-routed to the liver and cause chronic liver disease, according to Eksteen and colleagues in the December 1 issue of The. (Apr. (Science Daily)
Antidepressant ineffective against autism spectrum disorder children's obsessive behavior Jun 2, 2009
Headquartered in Manhasset, NY, The Feinstein Institute for Medical Research is home to international scientific leaders in cancer, leukemia, lymphoma, Parkinson's disease, Alzheimer's disease, psychiatric disorders, rheumatoid arthritis, lupus, sepsis, inflammatory bowel disease, diabetes, human genetics, neuroimmunology, and medicinal chemistry. Feinstein researchers are developing new drugs and drug targets, and producing results where science meets the patient, annually enrolling some 10,000... (EurekAlert!)
UCLA cancer researchers first to link intestinal inflammation with systemic chromosome damage Jun 1, 2009
Conditions that cause intestinal inflammation include Crohn's disease, inflammatory bowel disease, ulcerative colitis and Celiac disease ... 2 million Europeans currently suffer from inflammatory bowel diseases and incidence worldwide is increasing, Schiestl said. (EurekAlert!)
Ore Pharmaceuticals gets Nasdaq notice May 29, 2009
Ore is trying to find at least $10 million in financing or a partner to support clinical trials of a compound to treat inflammatory bowel disease. Reader Comments. (Washington Business Journal, DC)
La Jolla Institute unlocks mystery of potentially fatal reaction to smallpox vaccine May 25, 2009
" ### About La Jolla Institute Founded in 1988, the La Jolla Institute for Allergy ology is a nonprofit medical research center dedicated to increasing knowledge and improving human health through studies of the immune system. Scientists at the institute carry out research searching for cures for cancer, allergy and asthma, infectious diseases, and autoimmune diseases such as diabetes, inflammatory bowel disease and arthritis. La Jolla Institute's research staff includes more than 100 Ph.Ds and... (EurekAlert!)
Babies Born To Native High-altitude Mothers Have Decreased Risk Of Low Birth Weight May 20, 2009
26, 2006) Inflammatory bowel disease roughly doubles the chances of pregnancy complications, reveals research published ahead of print in Gut. Inflammatory bowel disease, or IBD for short, is an umbrella term. (Science Daily)
Pearl Jam's McCready to perform anthem May 18, 2009
The performance is part of a special evening to raise funds and awareness for people living with inflammatory bowel diseases ... Commonly referred to as inflammatory bowel disease or IBD, it is estimated that more than 1 ... For more information on CCFA and/or inflammatory bowel disease, please visit www. (MLB.com -- Seattle Mariners)
Ore Pharmaceutials cuts losses May 16, 2009
Ore, known as before selling off its genomics services division, is working against a brutal economy to get at least $10 million in financing or a larger partner to help fund further clinical trials of its lead compound to treat inflammatory bowel disease. The company had $7. (Washington Business Journal, DC)
No longer afraid to be a bridesmaid or travel with the boss May 14, 2009
Currently, the treatments for ulcerative colitis, an inflammatory bowel disease, include a fistful of pills -- up to a cumbersome 12 a day that reduce the risk of flares but that many forget to take, as well as steroids or surgery to remove their colon ... "Managing stress is really important for managing inflammatory bowel disease," Keefer said ... Keefer said the trial is one of the few NIH-funded behavioral studies for inflammatory bowel disease, which affects between 250,000 to 500,000... (EurekAlert!)
Women Have A More Powerful Immune System Than Men, Study Shows May 13, 2009
18, 2007) New data generated in mice has provided support for the hypothesis that defects in the innate immune system might underlie some cases of inflammatory bowel disease -- a group of disorders. (Dec. (Science Daily)
Two Causes For Bowel Disease In Infants Suggested By New Research May 4, 2009
24, 2007) People with inflammatory bowel disease may also be at risk for developing nerve damage and other neurological problems, according to recent. (May 1, 2009) MR enterography is an effective tool to evaluate and guide treatment of patients with Crohn's Disease (a common form of inflammatory bowel disease that typically affects young people) without ... 26, 2006) Inflammatory bowel disease roughly doubles the chances of pregnancy complications, reveals research published ahead of print in... (Science Daily)
Low Vitamin D Causes Problems For Acutely Ill Patients May 3, 2009
ScienceDaily (May 2, 2009) A group of endocrinologists in Sydney have observed that very sick patients tend to have very low levels of Vitamin D. The sicker they are, the lower the levels. Dr Paul Lee, Professor John Eisman and Associate Professor Jackie Center, researchers at Sydney's Garvan Institute of Medical Research, examined a cohort of 42 Intensive Care Unit (ICU) patients. (Science Daily)
MR Enterography Eliminates Unnecessary Radiation Exposure In Patients With Small Bowel Disease May 1, 2009
ScienceDaily (May 1, 2009) MR enterography is an effective tool to evaluate and guide treatment of patients with Crohn s Disease (a common form of inflammatory bowel disease that typically affects young people) without exposing them to radiation, according to a study performed at the Warren Alpert School of Medicine/Brown University in Providence, RI. ... 24, 2007) People with inflammatory bowel disease may also be at risk for developing nerve damage and other neurological problems, according to... (Science Daily)
Microbial bliss May 1, 2009
Diseases of the intestines: Studies have shown moderate to good effect for treating or preventing inflammatory bowel disease, and also for a milder condition called irritable bowel syndrome. Intestinal infection: One of the best-studied benefits of probiotics is preventing diarrhea caused by bacteria that occupy the gastrointestinal (GI) tract after it has been scoured clean of bacteria by antibiotics. (Why Files)
Ten top superfoods May 1, 2009
Helps with inflammatory intestinal disorders, including inflammatory bowel disease. Helps alleviate allergic conditions like asthma and eczema. (iAfrica.com)
Are colonoscopies really necessary for people over 50? Apr 28, 2009
Persons with a family history of colon cancer at an early age, or a history of inflammatory bowel disease such as ulcerative colitis, may benefit from screening at an earlier age and may be best served with colonoscopy rather than the other screening techniques. Next question. (CNN -- Health)
VITAMIN D IN KIDS: Pediatricians say children need more Apr 20, 2009
"There are children with chronic disease such as epilepsy, celiac disease and inflammatory bowel disease who need much higher vitamin D doses to avoid vitamin D deficiency.". The new recommendations from the Academy of Pediatrics include. (USA Today -- News)
Protect yourself against colon cancer with regular screenings, tests Apr 17, 2009
However, screening may need to be performed sooner if you or a close relative have colon polyps or colorectal cancer, inflammatory bowel disease (such as Crohn's disease or ulcerative colitis), or other bowel symptoms that would warrant earlier investigation (such as a change in bowel habits or blood in your stool. Your family doctor can help determine when the screening should occur. (Taylor Daily Press, TX)
