Low Birth Weight And Diabetes Have A Common Genetic Background Nov 14, 2009
"Indications of genetic associations are usually only found in very large populations. As we see here, it is important to substantiate these in smaller, but very well-phenotyped study populations. We can thus gain information about the possible mechanism of the original results," emphasized PD Dr. Thomas Illig, head of the Epidemiology -- Biological Samples -- Genomics research unit at Helmholtz Zentrum M. nchen. (Science Daily)
SPECIAL REPORT: Welcome to the Clone Farm Nov 13, 2009
It costs at least $15,000 to clone a cow and $4,000 to clone a sow, although improving efficiencies will likely lower those costs in coming years, said Mark Walton, president of ViaGen, a company in Austin, Texas, that provides animal cloning and genomics services. ViaGen owns the intellectual property rights to the technology that in 1996 produced Dolly the sheep, the world's first animal cloned from an adult cell, at Scotland's Roslin Institute. (The Star Online, Malaysia)
Ignite Institute to move to Fairfax Nov 12, 2009
Before setting his sights on Northern Virginia, Stephan was one of the original scientists at the Translational Genomics Research Institute in Phoenix, where 50 government, business and science leaders in 2002 raised $90 million for a six-story, 176,000-square-foot research building that opened its doors by 2004 ... Stephan left that venture last year as its deputy director of discovery research and head of its neurogenomics division, and had started up a new genetics testing services company,... (Washington Business Journal, DC)
10 blogs to make you think Nov 12, 2009
by Glyn Moody covers the application of open-source thinking to fields as wide-ranging as politics, genomics, content, and of course, software. is a former Microsoftie who has graduated to being one of most erudite authors on innovation, creativity, management, and now public speaking. (CNN)
Dangers Of Incapacitating Chemical Weapons And Widespread Misuse Of Riot Control Agents Nov 10, 2009
"Incapacitant research, if allowed to continue unchecked and in secret, may lead to even more dangerous developments. If the revolutionary advances in genomics, biotechnology and neuroscience are put to use by weapons designers then tomorrow's arsenals may well hold weapons that alter your thoughts and emotions, weaken your immune system, target your sight or leave you sterile.". Dangerous Ambiguities'also highlights the failure of the Chemical Weapons Convention (CWC) to adequately regulate... (Science Daily)
How Obama Can Bounce Back Nov 10, 2009
The Democrats should refocus the stimulus to prioritize necessary infrastructure, such as high-speed rail, universal high-speed Internet access, and fundamental R&D on genomics, robotics, and batteries. The president and his allies must also explain that health care reform is not merely morally compellingnobody should go without the security that comes from having health insurancebut also essential for our economic competitiveness. (Slate)
ChIA-PET: Novel Method For 3-D Whole Genome Mapping Research Nov 9, 2009
"The subsequent discovery of chromatin interactions between specific genes and specific enhancer sites generated a lot of interest to find chromatin interactions throughout the entire genome. Our study is one of the first to be able to address this 'Holy Grail' of genomics,'" she said ... D., Director of the Genomics Division at the Lawrence Berkeley National Laboratory, University of California, Berkeley, and Director of the U.S. Department of Energy Joint Genome Institute ... 9, 2006)... (Science Daily)
Findings Key For Understanding, Interpreting Genetic Testing For Long QT Syndrome Nov 9, 2009
D. A pediatric cardiologist at Mayo Clinic, Dr. Ackerman directs Mayo's Long QT Syndrome Clinic and is the director of the Mayo Clinic Windland Smith Rice Sudden Death Genomics Laboratory. See also. (Science Daily)
New Plastic Optical Fiber Technology May Revolutionize High Speed Last-mile Communication Networks Nov 9, 2009
12, 2008) Hot on the heels of a new supercomputer, plans for a new light-speed data line between the Translational Genomics Research Institute and Arizona State University could slash the time is takes to. . (Science Daily)
Entire DNA Sequenced for $1,700 Nov 7, 2009
Privately held Complete Genomics says it can do a better quality, usable genome map for about $4,400 -- compared with the $100 million the Human Genome Project spent to complete the first sequencing of the human genome in 2000 ... "This high-quality, cost-effective approach to genome sequencing will allow researchers to study complete genomes from hundreds of patients with a disease to advance the understanding of the genetic causes of that disease, with an end to preventing and treating common... (Newsmax)
Pathogen protection and virulence: Dark side of fungal membrane protein revealed Nov 7, 2009
Said Lawrence: "This transdisciplinary project has involved bioinformatics, functional genomics, molecular biology, biochemistry, plant pathology, immunology, and medical mycology. We first discovered the gene encoding TmpL by computational screening and analysis of the A. brassicicola genome at VBI. Further investigation of the tmpL sequence and functional genomics analysis has allowed us to build up a picture of what the protein may look like in many filamentous fungi.". Dr. Biswarup... (EurekAlert!)
Abraxis opens expanded plant in Phoenix, expected to create 200 jobs Nov 6, 2009
Dr. Daniel Von Hoff, senior investigator for the Translational Genomics Research Institute in Phoenix, is the principal investigator of the pancreatic cancer trial. Robert Green, president and CEO of the , said the opening of the Abraxis facility is another major success for the Arizona bioscience community. (Phoenix Business Journal, AZ)
Got $4,400? Buy a Used Car, or Map Your DNA Nov 6, 2009
Complete Genomics, a biotech company in Mountain View, Calif ... "We've ended up with a cost of sequencing that's ten times less than anyone else's," said Clifford Reid, president of Mountain View's Complete Genomics ... Between March and Sept., Complete Genomics sequenced the genomes of 14 people. (Fox News)
Domestic Horse Genome Sequenced Nov 6, 2009
"Horses and humans suffer from similar illnesses, so identifying the genetic culprits in horses promises to deepen our knowledge of disease in both organisms," said senior author Kerstin Lindblad-Toh, scientific director of vertebrate genome biology at the Broad Institute of MIT and Harvard and a professor of comparative genomics at Uppsala University in Sweden. "The horse genome sequence is a key enabling resource toward this goal.". (Science Daily)
Singapore scientists join international study of 10,000 vertebrates' genomes Nov 5, 2009
"The most challenging intellectual problem in biology for this century will be the reconstruction of our biological past so we can understand how complex organisms such as ourselves evolved," said Nobel Laureate Sydney Brenner, M.D., who co-heads Singapore's Institute of Molecular and Cell Biology (IMCB) comparative genomics laboratory, which will participate in The Genome 10 K Project ... D., who heads IMCB's comparative genomics lab and is one of the chairpersons of the Genome 10K committee,... (EurekAlert!)
First Draft Of The Pig: Researchers Sequence Swine Genome Nov 4, 2009
(June 10, 2005) Beijing Genomics Institute (BGI) of the Chinese Academy of Sciences (CAS) and the Danish Committee of Pig Breeding and Production (DCPBP) jointly announce the public release of pig genomic sequences ... 5, 2005) A large group of scientists led by the Beijing Institute of Genomics is publishing a much improved, near-complete genome analysis of the indica and japonica subspecies of O. sativa, which are eaten. (Science Daily)
Human Biological Complexity Mechanism Found Nov 4, 2009
Fernandez and Chen, now a senior researcher in Beijing, China, cross-analyzed databases on genomics, protein structure, microRNA regulation and protein expression in such troublesome paralogs. "The longer these duplicate genes stick around due to inefficient selection, the more likely they are to suffer a random mutation," Fernandez said. (Science Daily)
WCMC-Q biomedical research program builds scientific knowledge, technical workforce in Qatar Nov 3, 2009
Even more significantly, the successful project validates the capabilities of the WCMC-Q genomics lab and its ability to apply the most advanced technologies to biomedical research in Qatar ... Plus initiation of core capabilities in research laboratories, including the genomics and proteomics cores, computational biology and biostatistics core, a vivarium, a microscopy core, and a basic laboratory support core. (EurekAlert! -- Business News)
TGen seeks approval for swine flu test Oct 30, 2009
Phoenix-based is developing the new test at its Pathogen Genomics Division in Flagstaff. In addition to detecting the 2009 H1N1 virus, the test can quickly identify the strain and whether it may be resistant to the anti-viral drug Tamiflu, sold by Roche. (Phoenix Business Journal, AZ)
TGen seeks emergency FDA approval of new swine flu test Oct 30, 2009
Oct. 29, 2009 The Phoenix-based non-profit Translational Genomics Research Institute (TGen) announced today that, along with a business collaborator, it will submit a request to the U.S. Food and Drug Administration for emergency use of a new test to diagnose the 2009 H1N1 swine flu virus ... The new test, developed at TGen's Pathogen Genomics Division (TGen North) in Flagstaff, can not only detect influenza as some tests do now but also can quickly inform doctors about what strain of flu... (EurekAlert!)
Research center gets $4M Oct 27, 2009
-- 797,000 to Genomics for Southern Crop Stress and Disease at Mississippi State University to study crop genomics. The spending bill must still receive final approval in the Senate and House before it is sent to the White House to be signed into law by President Obama. (Greenville Delta Democrat Times, MS)
Genome Of Microbe Silently Shaping Ecology Of Ocean Dead Zones Described Oct 24, 2009
Susannah Tringe, a metagenomics scientist at the DOE JGI, said that the OMZs are sinks for an essential nutrient that marine organisms need to survive--nitrogen--as well as sources for the greenhouse gases methane and nitrous oxide ... The project is part of the DOE JGI's Community Sequencing Program established in 2004 to take on large-scale genomics efforts in support of DOE mission areas, including characterizing the biological and environmental processes involved in carbon cycling. (Science Daily)
Genome analysis changes diagnosis Oct 24, 2009
" The boy has congenital chloride diarrhoea which affects one in 50,000 people. The main clinical symptom is continual watery diarrhoea which causes dehydration and other metabolic disorders. If untreated, sufferers can go on to develop kidney disease, inflammatory bowel disease and may have fertility problems. More patientsThe scientists then looked at 39 patients who had the same condition the boy was originally thought to have and found that five them had the same genetic mutation. All five... (BBC News -- Health)
Ancient Bison Genetic Treasure Trove For Farmers Oct 24, 2009
Researchers from the University's Australian Centre for Ancient DNA (ACAD) worked with an international team of genomics researchers to analyse the genetic mutations of an ancient bison, many modern cattle breeds and members of the larger ruminant family tree, including deer, antelopes, and giraffes. Their findings, published in the Proceedings of the National Academy of Sciences today, open the way for identifying important mutations in the ancestors of domestic animals, says ACAD Director... (Science Daily)
Brigham and Women’s Hospital selects next president Oct 23, 2009
At the National Heart, Lung, and Blood Institute, one of 27 institutes making up the National Institutes of Health, Nabel focused on programs in stem cell biology, global health and chronic diseases in developing countries, health and prevention education, research by young scientists, and the genetics and genomics of heart, lung, and blood disease. For most of her tenure as director, the National Institutes of Health budget was flat, said Victor J. Dzau, chancellor for health affairs and chief... (Boston Globe)
Genomic Selection Making Its Mark on Dairying Oct 23, 2009
And, genomics is a better predictor of an animal s true genetic potential, he added. With genomic evaluations, bull studs will be able to focus only on additive genetics, Cowan offered. (Minnesota Farm Guide, MN)
Side-Out Foundation teams with leading medical professionals to battle breast cancer Oct 23, 2009
Located in the Debi and Jerry Bisgrove Research Pavilion of Scottsdale Healthcare's Virginia G. Piper Cancer Center, TCRS is a partnership of the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare ... TGen Drug Development Services (TD2), a wholly owned subsidiary of the Translational Genomics Research Institute (TGen), is a 501(c)3 non-profit organization ... The Translational Genomics Research Institute (TGen) is a non-profit organization dedicated to conducting... (EurekAlert! -- Business News)
Possible Link Between Autism And Oxytocin Gene Via Non-DNA Sequence Mutation Oct 23, 2009
22, 2009) Researchers at Duke University Medical Center have uncovered a new genetic signature that correlates strongly with autism and which doesn't involve changes to the DNA sequence itself. Rather, the changes are in the way the genes are turned on and off. (Science Daily)
Standards for a new genomic era Oct 22, 2009
"My hope is all the major genome centers and advanced genomics groups use the gradations that fit their needs," said Chris Detter, LANL Genome Science Group Leader and Joint Genome Institute-LANL Center director. "Some centers may want all six, while some may only want three, but as long as they keep them intact, we are in good shape. Then, my hope is that the smaller genomics groups adopt the classes as written to help the rest of the scientific community know what they are generating and... (EurekAlert!)
Creation of new orthopedic research alliance announced Oct 22, 2009
(October 20, 2009) The creation of the Translational Orthopedic Research Program (TORP), a new partnership of Van Andel Research Institute (VARI) and its affiliate the Translational Genomics Research Institute (TGen), Spectrum Health, Orthopaedic Associates of Michigan (OAM), and the Michigan State University (MSU) College of Human Medicine, was announced today by officials of the sponsoring organizations who gathered at Van Andel Institute for the World Osteoporosis Day Summit, a meeting... (EurekAlert! -- Business News)
Research partnership will study how electronic medical records can address genetics of drug safety Oct 22, 2009
Nation's premier health maintenance research group to collaborate with innovative international genomics research consortium. Chicago (October 21, 2009) The International Serious Adverse Events Consortium (SAEC) announced today it will collaborate with the HMO Research Network (HMORN) to improve the safe use of drugs by exploring why the genetic makeup of some individuals makes them more likely to experience serious drug-related adverse events (SAEs). (EurekAlert! -- Business News)
UK urged to lead on future food Oct 21, 2009
" GM divideIn June, the UN Food and Agriculture Organization said there were now one billion hungry people in the world - "the first time in history" there had been so many. Celebrities such as Sir Paul McCartney have embraced the anti-GM cause Although it said rising unemployment and lower incomes were to blame for recent increases in the number of hungry people, investment in science to increase the supply of food was also needed. The Royal Society says the UK should spend 200m per year for... (BBC News -- UK)
Combimatrix Molecular Diagnostics Strengthens Management Team Oct 21, 2009
This technology has a wide range of potential applications in the areas of genomics, proteomics, biosensors, drug discovery, drug development, diagnostics, combinatorial chemistry, material sciences and nanotechnology. Other technologies include proprietary molecular synthesis and screening methods for the discovery of potential new drugs. (Primezone Releases)
Scientists Identify Enzyme That Could Help Grow Biofuel Crops In Harsh Environments Oct 21, 2009
This research was funded by the DOE-United States Department of Agriculture Plant Feedstock Genomics program and by DOE's Office of Science. Adapted from materials provided by. (Science Daily)
Man allegedly takes car on 1,000-mile test drive Oct 20, 2009
Its organizer, the X Prize Foundation, is best known for the Ansari X Prize, which led to the first manned private spaceflight in 2004 and is also sponsoring contests in genomics, health care and a moon landing. Police stop driver for 15 violations in 11 minutes. (Fresno Bee)
Scan Of Turkish Infant's Genome Yields A Surprise Diagnosis Oct 20, 2009
18, 2008) Australian researchers have launched the world first detailed map of the kangaroo genome, completing the first phase of the kangaroo genomics. (Oct. (Science Daily)
'H1N1 vaccine remarkably safe' Oct 20, 2009
Collins said NIH will continue to fund basic science, but he also hopes to support the use of powerful new research tools, including new imaging technologies and genomics -- studying the DNA map to find causes of diseases. He also hopes to support the use of powerful computers to make medical discoveries and nanotechnology, the design and manipulation of ultra-tiny materials. (India Times)
Video: Progressive Insurance Automotive X Prize Announces Teams Qualified to Compete for $10 Million and Launches National Student Contest Oct 20, 2009
In 2004, the Foundation captured world headlines when Burt Rutan, backed by Microsoft co-founder Paul Allen, built and flew the world's first private vehicle to space to win the $10 million Ansari X PRIZE. The Foundation has since launched the $10 million Archon X PRIZE for Genomics, the $30 million Google Lunar X PRIZE, and the $10 million Progressive Insurance Automotive X PRIZE. The Foundation is creating and conducting competitions in four prize groups: Exploration (Space and Oceans), Life... (Yahoo! Wire -- Entertainment News)
WFU participating in H1N1 vaccine trial Oct 20, 2009
The study, to be conduced by Wake Forest's Center for Genomics and Personalized Medicine Research, is co-sponsored by the National Institutes of Health and is meant to determine the safety of the vaccine in people with asthma and the dose needed to induce a protective immune response. Studies have indicated that people who have asthma may be particularly at risk for the 2009 H1N1 flu virus. (Triad Business Journal, NC)
No Such Thing As 'Junk RNA,' Say Researchers Oct 19, 2009
21, 2006) University of Iowa scientists have made a discovery that broadens understanding of a rapidly developing area of biology known as functional genomics and sheds more light on the mysterious, so-called. (May 15, 2008) RNA is best known as a working copy of the DNA sequence of genes. (Science Daily)
Characterization of the oxidative stress stimulon and PerR regulon of Campylobacter jejuni Oct 19, 2009
BMC Genomics 2009, 10:481doi:10. 1186/1471-2164-10-481. (BioMed Central)
City Beat (5) Oct 18, 2009
Dr. Charis Eng, director of the Genomic Medicine Institute at the Cleveland Clinic, discusses the DNA link between wine and genomics in Take Two Genes, A Glass of Wine and Call Me in the Morning at the Maltz Museum of Jewish Heritage at 7. Reservations at 216-444-6418. (Cleveland Jewish News, OH)
TraDIS technique tackles typhoid Oct 17, 2009
"Sequencing centres such as ours can produce vast amounts of genomic data at a pace unimaginable just a few years ago," explains Professor Julian Parkhill, Director of Sequencing and head of Pathogen Genomics at the Sanger Institute. "One of our aims is to develop high-throughput research methods that can exploit this explosion of genetic data, to ensure these resources can be used effectively. We can now discover which of all the genes in an organism are essential to its survival or required... (EurekAlert!)
Is it worth testing your genes? Oct 17, 2009
According to Dr. Muin J. Khoury, director of the Office of Public Health Genomics at the U.S. , some 1,800 to 2,000 genetic tests have been developed, most of which are relevant only to rare genetic conditions that don't affect too many people. "A growing number of these tests are suggested to be used to target interventions (pharmacogenetics), and to do early detection or susceptibility testing," Khoury said. (USA Today -- News)
Are Commercial Genetic Tests Worth Taking? Oct 16, 2009
According to Dr. Muin J. Khoury, director of the Office of Public Health Genomics at the U.S. Centers for Disease Control and Prevention, some 1,800 to 2,000 genetic tests have been developed, most of which are relevant only to rare genetic conditions that don't affect too many people ... D., director, Office of Public Health Genomics, U.S. Centers for Disease Control and Prevention, Atlanta; Marc S. Williams, M.D., director, clinical genetics, American College of Medical Genetics, and director,... (MEDLINEplus)
Is autism genetic? Researchers close to answer Oct 16, 2009
"That is both exciting as well as daunting," says Aravinda Chakravarti, who directs the Center for Complex Disease Genomics of the McKusick-Nathans Institute of Genetic Medicine at Johns Hopkins, in Baltimore, Maryland ... The alterations were in a "conserved" part of the genetic code, meaning it's pretty much the same in all animals, from mouse to man, notes Dr. Hakon Hakonarson, who led the research and also directs the Center for Applied Genomics at the Children's Hospital of Philadelphia, in... (CNN -- US)
Using RNAi-based Technique, Scientists Find New Tumor Suppressor Genes In Lymphoma Oct 15, 2009
The findings of this study are a vital complement to genomics approaches to map the cancer genome, the altered DNA sequence of cancer patients. While this strategy will help build a catalog of every genetic mutation lurking within a cancer cell s DNA, our approach offers functional information, such as which genes are causally involved in promoting cancer -- knowledge that can be exploited to design better, targeted therapies, said Professor Scott Lowe, Ph. (Science Daily)
Helicos BioSciences wins $2.9M grant Helicos looks to capitalize on good news Oct 15, 2009
This represents a major shift in the way we expect human genomics to be carried out in the future, with the hope of ultimately impacting human disease, Chief Scientific Officer Patrice Milos said at the time. It s not the first time that a human genome has been sequenced. (Boston Business Journal, MA)
AMP commends SACGHS on their DNA patent report Oct 15, 2009
The Association for Molecular Pathology is an international medical professional association dedicated to the advancement, practice, and science of clinical molecular laboratory medicine and translational research based on the applications of molecular biology, genetics and genomics. Through the efforts of an enthusiastic membership from across the United States and around the world, AMP continues to grow in numbers and influence. (EurekAlert! -- Business News)
What Drives Genes? Human Epigenome Mapped Oct 15, 2009
Recognizing the central role of the epigenome in many areas of biology and medicine the National Institutes of Health launched a five-year Roadmap Epigenomics Program in 2008 ... The current study, to which Ren and additional members of the Center located at the University of Wisconsin and the Morgridge Institute for Research in Madison, Wisconsin, also contributed, is not only the first complete high-resolution map of an epigenome superimposed on the human genome, but also the first study to be... (Science Daily)
Forensics firm builds on genomic discovery to advance DNA-based identification Oct 14, 2009
Casework Genetics technology features genomic techniques developed by the Translational Genomics Research Institute (TGen) and the University of California, Los Angeles (UCLA) ... Dr. David Craig, Associate Director of TGen's Neurogenomics Division and a co-discoverer of the technology, said Casework Genetics has the ability to significantly impact the field of forensic identification ... The Translational Genomics Research Institute (TGen) is a Phoenix, Arizona-based non-profit organization... (EurekAlert! -- Business News)
Cautious investors bring venture capital fund-raising to 15-year low Oct 13, 2009
Gullans said the Excel fund is being invested in start-ups in health care information technology, medical devices and diagnostic tools, and new biotechnology and life sciences applications, including biofuels and synthetic genomics. These niches have been expanding faster than other venture-backed businesses, said Gullans. (Boston Globe)
St. Louis' King of Algae Oct 13, 2009
This summer, Exxon Mobil entered a $600 million partnership with California-based biotech company Synthetic Genomics for algae research and development. Research going on today in St. Louis is looking at whether blue-green algae, also called cyanobacteria, can be produced in mass quantities for fuel for airplanes and hybrid automobiles to help reduce worldwide greenhouse gas emissions and provide a lower-cost alternative to petroleum. (St. Louis Business Journal, MO)
Gene Data Tool Advances Prospects For Personalized Medicine Oct 12, 2009
D., director of the Center for Applied Genomics at The Children's Hospital of Philadelphia, suggests that their technique, applied to appropriate complex multigenic diseases, improves the prospects for personalizing medicine to an individual's genetic profile ... D., Haitao Zhang, Jonathan Bradfield, Cecilia Kim, Edward Frackleton, Cuiping Hou, Joseph T. Glessner, and Rosetta Chiavacci, all of the Center for Applied Genomics; Charles Stanley, M.D., of the Division of Endocrinology; and Dimitri... (Science Daily)
Computer Simulations Validate Treatment Targets For Lung Cancer Oct 12, 2009
12, 2009) Using computer modeling, the Translational Genomics Research Institute and Scottsdale Healthcare have discovered lung cancer 'pathways' that could become targets for new drugs, according to a scientific paper published online today by the Journal of Thoracic Oncology. See also. (Science Daily)
King of Algae Oct 11, 2009
This summer, Exxon Mobil entered a $600 million partnership with California-based biotech company Synthetic Genomics for algae research and development ... This summer, Exxon Mobil entered a $600 million partnership with California-based biotech company Synthetic Genomics, based in nearby La Jolla, for algae research and development. (St. Louis Business Journal, MO)
* Taiwanese team discovers rices flood-tolerant gene Oct 11, 2009
Lee Kuo-wei (), the first author of the paper and the prime contributor to the rice genomics study, said the teams research found that rice is the only crop that can survive in flooded fields because of the CIPK15 gene. Most plants die when submerged in water because the diffusion of oxygen is limited, restricting aerobic metabolism and energy production. (Taipei Times, Taiwan -- World)
New portal for plant genomics will support research into improved crops Oct 9, 2009
Today sees the launch of Ensembl Plants a freely available web resource for plant genomics research by the European Molecular Biology Laboratory's European Bioinformatics Institute (EMBL-EBI), in partnership with the Cold Spring Harbor Laboratory, USA. Ensembl Plants allows researchers worldwide to access and visualise the results of genome-scale experiments in different plant species. By pinpointing the genetic basis of beneficial characteristics such as drought and pest resistance, Ensembl... (EurekAlert! -- Business News)
Untangling cancer’s genetic trajectory Oct 9, 2009
As an early look into the tangled genomics of cancer, the study is a good first step, says Michael Gould, an oncologist at the University of Wisconsin-Madison School of Medicine and Public Health. In this data from one patient, the original tumor had a lot fewer meaningful mutations than previous reports on breast cancer cell lines. (Why Files)
New Target For Treating Leukemia Identified Oct 9, 2009
However, this finding was somewhat puzzling as EGFR is not expressed in AML. The researchers made use of sophisticated cross-disciplinary approaches to study gene expression (genomics) and protein structure and function (proteomics) to elucidate the molecular basis for the effect of EGFR inhibitors in AML.. Spleen tyrosine kinase (Syk) was identified as a target in AML. Syk is expressed in blood cells and is critical for proper blood cell differentiation. (Science Daily)
DNA Damage, Aging, and Cancer Oct 8, 2009
From the Department of Genetics, Cancer Genomics Center, Erasmus University Medical Center, Rotterdam, the Netherlands. Address reprint requests to Dr. Hoeijmakers at the Department of Genetics, Cancer Genomics Center, Erasmus University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, the Netherlands, or at j.hoeijmakers@erasmusmc. (New England Journal of Medicine)
Proposal: $500 million gigantic space gun could launch half-ton (almost) payloads Oct 8, 2009
Firms that do basic genetic tests to warn of health risks should be clearer about what such forecasts can tell you, says genomics pioneer Craig Venter. Most read. (Harper's Magazine)
Cash helps TGen, UA with drug research Oct 7, 2009
The Translational Genomics Research Institute and University of Arizona will split a $7 ... What it is: Translational Genomics Research Institute is a non-profit. (AZCentral -- Business)
TGen and Scottsdale Healthcare discover new 'pathways' Oct 7, 2009
Oct. 7, 2009 Using computer modeling, the Translational Genomics Research Institute and Scottsdale Healthcare have discovered lung cancer 'pathways' that could become targets for new drugs, according to a scientific paper published online today by the Journal of Thoracic Oncology ... The Translational Genomics Research Institute (TGen) is a Phoenix, Arizona-based non-profit organization dedicated to conducting groundbreaking research with life changing results. (EurekAlert!)
New Drug Aims To 'Seek And Destroy' Many Types Of Cancer Oct 7, 2009
TCRS is a partnership of the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare. The partnership allows molecular and genomic discoveries made by TGen and others around the world to reach the patient bedside in the Virginia G. Piper Cancer Center at Scottsdale Healthcare as quickly as possible through clinical trials with agents directed at specific targets in patients tumors. (Science Daily)
