Certain Reflux Drugs Tied to Higher Post-Angioplasty Death Rate Nov 18, 2009
PPIs are frequently given with aspirin and Plavix after an angioplasty procedure to reduce the chances of gastrointestinal bleeding. Many people also take PPIs for various gastrointestinal conditions, including acid reflux, gastric ulcers and stomach bleeding. (MEDLINEplus)
Ulcer meds may up heart surgery risk Nov 18, 2009
() -- Heart patients who take certain stomach-acid-suppressing drugs to prevent gastrointestinal bleeding may be at increased risk of dying after a cardiac procedure, according to a study presented at the annual meeting of the American Heart Association (AHA) in Orlando, Florida. Researchers at Mount Sinai Medical Center, in New York City, reported that patients who underwent angioplasty, a procedure to clear blocked blood vessels in the heart, were 30 percent more likely to die if they were... (CNN)
The truth about aspirin Nov 9, 2009
- Women ages 55 to 79 should take aspirin if the chance of reducing an ischemic stroke outweighs the potential harm of an increase in gastrointestinal bleeding. - Women younger than 55 and men younger than 45 who have never had a stroke or heart attack should not take aspirin for prevention. (India Times, India)
Risks of daily aspirin may outweigh benefits Nov 5, 2009
Aspirin can cause gastrointestinal bleeding and other problems ... Aspirin can cause gastrointestinal bleeding and other problems--some of them serious ... Risks include gastrointestinal bleeding and a small, but potentially devastating, risk of bleeding in the brain. (CNN -- Health)
Heart Patients Running The Red Light On Traffic Restrictions Oct 30, 2009
9, 2009) Following an acute coronary syndrome such as a heart attack or unstable angina, patients who receive a medication to reduce the risk of gastrointestinal bleeding that may be associated with the use. . (Science Daily)
People With Heart Devices Can 'Digest' Advanced Diagnostic Technology Safely Oct 28, 2009
In a large majority of cases (74 percent), the reason for performing the CE was to locate gastrointestinal bleeding. In each case, the capsule explored the entire length of the small bowel. (Science Daily)
Calling It In: New Emergency Medical Service System May Predict Caller's Fate Oct 23, 2009
18, 2008) Gastrointestinal bleeding can be fatal -- something which is not known to many alcoholics. More than 400 patients from the major German cities of Leipzig and Munich were included in the study. (Science Daily)
Redefining Dementia as a Terminal Illness Oct 15, 2009
Thirty-one residents suffered major health events, such as seizure, gastrointestinal bleeding, heart attack or stroke, but only in rare cases did those events lead to death. Only seven patients had a major event during the final three months of life. (Time.com)
Does it help to take non-steroidal anti-inflammatory drugs like ibuprofen for colds? Oct 12, 2009
And do take these medications - dubbed NSAIDS - judiciously, because they carry significant side effects such as gastrointestinal bleeding. In a recent review of nine randomized, controlled studies of NSAIDS published by the Cochrane Collaboration, an international nonprofit that analyzes health care information, researchers from the Kangdong Sacred Heart Hospital in South Korea concluded that NSAIDS can help with the aches and pains of the common cold, though not the pain of sore throats. (Boston Globe)
Judge says inmate can refuse blood transfusion Oct 10, 2009
Senior Judge Keith B. Quigley said inmate Anthony Lindsey s wishes must be respected under the First Amendment, whether they are based on religion or something else. "Official Web Site of Jehovah's Witnesses for Reform on Blood". (Somerset Daily American, PA)
Getting the word out on dangers of acetaminophen overdose Oct 5, 2009
Non-steroidal anti-inflammatory drugs such as ibuprofen carry a risk of gastrointestinal bleeding. The Consumer Healthcare Products Association, a trade group for companies that manufacture over-the-counter medicines, critiqued some of the recommendations, and emphasized the safety of acetaminophen when used as directed. (Boston Globe)
Common Spices May Suppress E. Coli Sep 26, 2009
E. coli O157 toxins cause abdominal cramps, bloody diarrhea, acute renal failure and gastrointestinal bleeding. Scientists from the University of Tokushima in Japan studied extracts of 20 different kitchen spices, including allspice, anise seed, black pepper, cardamom, cayenne pepper, cinnamon, and clove and their effects on the growth and production of toxins found in E. coli. (Newsmax)
Cogent trial shows lack of adverse interaction between clopidogrel and stomach medicine Sep 25, 2009
The purpose of the trial was to determine whether the administration of clopidogrel and omeprazole is safe and effective in reducing the incidence of gastrointestinal bleeding and symptomatic ulcer disease in the setting of concomitant aspirin therapy. The primary endpoint of the trial was a composite of upper gastrointestinal clinical events, including gastroduodenal bleeding, symptomatic gastroduodenal ulcer, and persistent pain with multiple gastric erosions, obstruction or perforation. (EurekAlert!)
Reflux Drugs OK with Blood Thinners Sep 3, 2009
Doctors often prescribe PPIs along with anti-clotting drugs to reduce the risk of gastrointestinal bleeding. "The current findings provide some reassurance to clinicians that PPIs and clopidogrel [Plavix] can be safely combined in patients in whom there is a strong indication to use both drugs," said lead researcher Dr. Michelle O'Donoghue, an investigator in the TIMI Study Group at Brigham and Women's Hospital in Boston. (MEDLINEplus)
New Anti-Clotting Drug Beats Plavix Sep 1, 2009
However, patients taking ticagrelor were more likely to have spontaneous intracranial and gastrointestinal bleeding than people taking clopidogrel (4. 5 percent versus 3. (MEDLINEplus)
Surgical treatment a rare complication of duodenal diverticulum Aug 26, 2009
In general, angiography and endoscopy are the most useful modalities for diagnosing and managing gastrointestinal bleeding. However, duodenal diverticular hemorrhage complicated by duodenal obstruction can happen after transcatheter arterial embolization by ischemic damage to the duodenum or fibrotic encasement of the duodenum. (EurekAlert!)
Mary Elizabeth Gibb, onetime nurse at St. Pius X Catholic High School Aug 23, 2009
Mrs. Gibb, 60, of Norcross, died at home Monday of gastrointestinal bleeding, Emily said. Jeff said he and members of his opera company will sing at her funeral. (Atlanta Journal-Constitution -- Metro)
Healing power? Aug 20, 2009
This can lead to gastrointestinal bleeding and strokes caused by bleeding, known as hemorrhagic strokes ... General guidelines call for men ages 45 to 79 and women ages 55 to 79 to take aspirin if benefits, such as preventing or strokes, outweigh possible problems, such as gastrointestinal bleeding, Johnson said. (CNN)
Endoscopy within 24 hours shows better outcomes in elderly with peptic ulcer bleeding Aug 18, 2009
Researchers from University Hospitals Case Medical Center in Cleveland, Ohio, note that unless specific contraindications exist, the data supports the routine use of early endoscopy for upper gastrointestinal bleeding ... In 2006, there were an estimated 220,000 hospital discharges for upper gastrointestinal bleeding, with more than 118,000 of these attributed to peptic ulcer disease. (EurekAlert!)
Students share hope, help for breaking the cycle of self-destructive behavior Aug 15, 2009
Fatal abnormalities in heart rhythm can occur, the stomach can perforate from binging, and vomiting can cause tears in the esophagus, gastrointestinal bleeding, and ulcers. The more serious health risks take longer to be detected or to become worrisome enough for the people with eating disorders to seek help. (Ontario Argus Observer, OR)
Aspirin May Stem Deaths from Colorectal Cancer Aug 13, 2009
Aspirin can cause side effects, including gastrointestinal bleeding. Further studies, including placebo-controlled trials of aspirin and other anti-inflammatory agents, are needed, he said. (MEDLINEplus)
Aspirin Use After Colorectal Cancer Diagnosis Associated With Improved Survival Aug 13, 2009
"These results suggest that aspirin may influence the biology of established colorectal tumors in addition to preventing their occurrence. Our data also highlight the potential for using COX-2 or related markers to tailor aspirin use among patients with newly diagnosed colorectal cancer. Nonetheless, because our data are observational, routine use of aspirin or related agents as cancer therapy cannot be recommended, especially in light of concerns over their related toxicities, such as... (Science Daily)
Cancer fighter Aug 12, 2009
But aspirin also can cause gastrointestinal bleeding that can be serious, so doctors are reluctant to tell patients to take it until they have solid evidence that its benefits outweigh any potential harm. Q: If studies confirm aspirin's benefits, how might that change treatment. (USA Today -- News)
VIPs And Lousy Healthcare Jul 10, 2009
I once had a patient with rectal bleeding try to talk me out of doing a rectal exam, to which I replied what I was taught in medical school, "There are only two reasons for not doing a rectal exam on a patient with gastrointestinal bleeding: no finger, no rectum." A test or a part of the physical exam may be uncomfortable for the patient but also lifesaving. 4) The patient's philosophy is "I can afford it. Let's do every test in the book." There are downsides to excessive testing, including body... (CBS News -- Health)
The FDA and Painkillers: What's Safe Now? Jul 3, 2009
Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are effective pain relievers, but when taken at high doses and for prolonged periods especially for the treatment of chronic pain in older adults they carry a risk of stomach ulcers and gastrointestinal bleeding. NSAIDs may also raise blood pressure and affect kidney function. (Time.com)
Panel backs painkiller limits Jul 1, 2009
Limiting access to acetaminophen may inadvertently lead people to switch to ibuprofen, which has its own safety risks including gastrointestinal bleeding, doctors from J&J s McNeil Consumer Healthcare unit told the panel. They proposed instead adding icons to alert consumers to acetaminophen in combination drugs and revising Tylenol labeling to encourage consumers to start with one caplet per dose and only take two if needed. (Boston Globe)
FDA Hopes To Reduce Painkiller Overdoses Jun 30, 2009
J&J also warned panelists that any new restrictions on acetaminophen would force patients to switch to nonsteroidal anti-inflammatory drugs, which carry risks of gastrointestinal bleeding and sometimes fatal kidney injury. "When switching occurs, the risk of death increases," said Dr. Kenneth Rothman, a consultant for J&J. According to figures from Rothman, a 30 percent switch away from acetaminophen would result in an additional 5,000 deaths per year. (Click2Houston, TX)
Blues great Koko Taylor gets musical sendoff Jun 16, 2009
She died June 3 at age 80 shortly after having surgery because of gastrointestinal bleeding. Another visitation will be held Friday afternoon also at Rainbow/PUSH headquarters, followed by her funeral with a eulogy to be delivered by the Rev. Jesse Jackson. (MSNBC -- Music)
* World News Quick Take Jun 5, 2009
She died of complications following a May 19 surgery for gastrointestinal bleeding. MEXICO Police detained after kidnap. (Taipei Times, Taiwan -- Sports)
Blues singer Koko Taylor, 80 Jun 4, 2009
CHICAGO - Blues icon Koko Taylor died Wednesday afternoon at age 80, after surgery May 19 to correct gastrointestinal bleeding. "She was recovering slowly but surely, and then she had a real bad night," said Marc Lipkin, a spokesman for Taylor's longtime Chicago-based label, Alligator Records. (Athens Banner-Herald)
Anti-Clot Drug Combinations Boost Bleeding Risks Jun 4, 2009
And patients who got all three drugs had a four-fold increase in the risk of gastrointestinal bleeding within one year, Abraham said. "These are significant gastrointestinal bleeding risks.". (MEDLINEplus)
Koko Taylor, at 80; her gritty, raw, and powerful voice helped define the blues Jun 4, 2009
Ms. Taylor died at Northwestern Memorial Hospital about two weeks after having surgery for gastrointestinal bleeding, said Marc Lipkin, director of publicity for her record label, Alligator Records. "The passion that she brought and the fire and the growl in her voice when she sang was the truth," blues singer and musician Ronnie Baker Brooks said yesterday. (Boston Globe)
Throat-zapping method may cut cancer risk May 28, 2009
One in the heat group suffered gastrointestinal bleeding and five developed narrowing of the esophagus. Click for related content. (MSNBC -- Health)
Bevacizumab in Hereditary Hemorrhagic Telangiectasia May 14, 2009
To the Editor: Hereditary hemorrhagic telangiectasia (HHT) (also known as the Osler Weber Rendu syndrome) is an inherited vascular dysplasia whose main features are mucocutaneous telangiectasias, epistaxis, gastrointestinal bleeding, and iron-deficiency anemia. 1 It is a disorder of unbalanced angiogenesis. (New England Journal of Medicine)
Aspirin in Middle Age May Cut Cancer Risk May 12, 2009
But regular use of the anti-inflammatory drug specifically for cancer prevention is not recommended now because it has been linked to a number of side effects, including gastrointestinal bleeding and stomach ulcers. Common cancers, such as prostate, breast, lung, and bowel, tend to develop after age 60. (Newsmax)
Plavix, Heartburn Drugs May Be Risky Combination May 8, 2009
In his clinical practice, Bailey said, he would consider continuing the combined drug therapy for stent recipients who had active gastrointestinal bleeding while taking Plavix. "They might benefit from PPI therapy," he said. (MEDLINEplus)
Benefits Of Anti-clotting Medications Reduced By Common Heartburn Drugs May 8, 2009
Overall, the incidence of hospitalization for upper gastrointestinal bleeding was only 1. 1% among patients taking a PPI and 0. (Science Daily)
The frequency of adverse drug reaction related admissions according to method of detection, admission urgency and medical department specialty May 4, 2009
Gastrointestinal bleeding due to NSAID, acetylsalicylic acid and warfarin was the most common ADR that resulted in admission and represented 40% of all certain ADRs (12/30) according to WHO causality criteria. Conclusions. (BioMed Central)
Nuvo announces 2009 first quarter financial results Apr 30, 2009
While, conventional oral NSAIDs expose patients to potentially serious systemic side effects such as gastrointestinal bleeding and cardiovascular risks, Nuvo's clinical trials suggest that some of these systemic side effects occur less frequently with topically applied Pennsaid. There are more than 27 million Americans suffering from osteoarthritis and the United States market for this condition is estimated at US$4 billion annually. (Canada Newswire)
ASA Plus Clopidogrel Reduces Heart Attack Risk In Patients With Acute Coronary Syndrome, Study Suggests Apr 29, 2009
28, 2009) In order to better prevent blood clots, clopidogrel can be prescribed to patients with acute ischaemia of the heart muscle, in addition to acetylsalicylic acid (ASA). The Institute for Quality and Efficiency in Health Care (IQWiG) has now investigated whether the combination of clopidogrel and ASA actually has a higher benefit for patients than ASA alone. (Science Daily)
Should marathon runners take a baby aspirin before a big race? Apr 20, 2009
It cautioned that the recommendations apply only when the potential reduction of stroke or heart attack risk outweighs the increased risk of gastrointestinal bleeding due to aspirin. Some doctors remain cautious. (Boston Globe)
New Tool Calculates Risk Of Bleeding In Heart Attack Patients Apr 17, 2009
8, 2008) People who have gastrointestinal bleeding after a stroke are more likely to die or become severely disabled than stroke sufferers with no GI bleeding, according to a new. . (Science Daily)
Electronic health records raise doubt Apr 13, 2009
For example, he said, an inaccurate diagnosis of gastrointestinal bleeding on a heart attack patient's personal health record could stop an emergency room doctor from administering a life-saving drug. Ideally insurance claims could provide a trove of data that could greatly accelerate the Obama administration's effort to computerize all medical records within five years. (Boston Globe)
Plagued by chronic pain? Treatment teams can help Mar 27, 2009
Other drugs have side effects too; even nonsteroidal anti-inflammatory drugs (NSAIDs), which include ibuprofen and naproxen, can cause gastrointestinal bleeding. "This is an area where more is not necessarily better," said Von Korff. (CNN -- Health)
Inmate Dies While In Custody Mar 25, 2009
The hospital told TDCJ that Bell's preliminary cause of death was gastrointestinal bleeding. The Harris County Medical Examiner's Office said the cause of his death is "pending further study" and may not be determined for several weeks. (Click2Houston, TX)
Experts Revise Guidelines on Daily Aspirin for Heart Mar 18, 2009
The issue of dosage has long been discussed because aspirin carries with it an increased risk for gastrointestinal bleeding, especially when taken in combination with the clot-dissolving drug clopidogrel (Plavix) ... Among the recommendations: Men aged 45 to 79 should take aspirin if the chances of preventing a heart attack outweigh the chances of gastrointestinal bleeding. (MEDLINEplus)
Aspirin recommendation underscores need for physicians and patients to discuss benefits and risk Mar 18, 2009
The task force found that men between the ages of 45 and 79 should use aspirin to reduce their risk for heart attacks when the benefits outweigh the harms for potential gastrointestinal bleeding; and that women between the ages of 55 and 79 should use aspirin to reduce their risk for ischemic stroke when the benefits outweigh the harms for potential gastrointestinal bleeding. The task force also recommended against the use of aspirin for stroke prevention in women younger than 55 years and for... (EurekAlert!)
New Aspirin Recommendation Can Help Prevent Heart Attacks & Strokes, Says Partnership for Prevention Mar 17, 2009
Aspirin should be used when the benefits outweigh the harms for potential gastrointestinal bleeding. "Encouraging doctors to discuss daily aspirin use with their patients is an important way to help people live longer and healthier lives," said Partnership Interim President Corinne G. Husten, MD, MPH. "We need to make sure that the health reform debate now gathering momentum in Congress gives top priority to increasing the delivery of clinically effective and highly cost-effective preventive... (PR Newswire)
Certain Combined Medications Following Heart Attack May Increase Risk Of Death Mar 10, 2009
9, 2009) Following an acute coronary syndrome such as a heart attack or unstable angina, patients who receive a medication to reduce the risk of gastrointestinal bleeding that may be associated with the use of the antiplatelet drug clopidogrel and aspirin have an increased risk of subsequent hospitalization for acute coronary syndrome or death, according to a new study. See also. (Science Daily)
Blood Thinner, Heartburn Drugs May Be Risky After Heart Attack Mar 5, 2009
Many doctors also prescribe proton pump inhibitors (PPIs), which are drugs used to help prevent gastric reflux, but they help prevent gastrointestinal bleeding while taking Plavix ... Dr. Gregg C. Fonarow, a professor of cardiology at the University of California, Los Angeles, thinks this study shows that PPIs used with Plavix should be limited to patients at risk of gastrointestinal bleeding ... Dr. Byron Lee, an associate professor of cardiology at the University of California, San Francisco,... (MEDLINEplus)
Weekend Admission May Be Riskier for Gastrointestinal Bleeding Mar 4, 2009
The second study found that people with peptic ulcer-related upper gastrointestinal bleeding admitted to hospitals on the weekend had a higher death rate (3. 4 percent vs. 3. (MEDLINEplus)
Blood thinner Plavix, Prilosec increase heart risk Mar 4, 2009
Two-thirds of these patients also took a Proton Pump Inhibitor (PPI) such as AstraZeneca Plc's heartburn drug Prilosec to cut the risk of gastrointestinal bleeding from blood thinners, and had almost twice the risk of suffering another cardiac arrest or bout of unstable angina compared to those not taking a PPI, the researchers said Tuesday. Dr. Michael Ho of the Denver VA Medical Center, who led the study, said this drug combination may be responsible for thousands of repeat heart attacks. (Xinhuanet, China)
Patients with GI bleeding admitted on the weekend have higher death rate Mar 1, 2009
"Future studies should explore alternative processes of care that may mediate these effects, as upper gastrointestinal bleeding represents a considerable clinical and economic burden.". The annual prevalence of upper gastrointestinal bleeding (UGIB) is approximately 170 per 100,000 people and cost is estimated at approximately $750 million. (EurekAlert!)
Alzheimer's Disease Feb 7, 2009
Because NSAIDs can cause serious gastrointestinal bleeding, clinical trials need to be completed before it's clear whether people should take NSAIDs solely to prevent Alzheimer's. Statins. (CNN -- Health)
Headaches & Migraines Feb 7, 2009
If taken too often or for long periods of time, NSAIDs can lead to ulcers, gastrointestinal bleeding and rebound headaches. Triptans. (CNN -- Health)
