Clinical Tests Begin On Medication To Correct Fragile X Defect Nov 4, 2009
are beginning a clinical trial of a potential medication designed to correct a central neurochemical defect underlying Fragile X syndrome, the most common inherited cause of intellectual disability ... The changes in turn appear to be the mechanism for learning deficits in Fragile X syndrome ... Thomas R. Insel, M.D., director of the National Institute of Mental Health, said, "This project is the culmination of years of fundamental research, first identifying the genetic mutation and later... (Science Daily)
Embracing their 'mascot' Oct 29, 2009
He was diagnosed with Fragile X syndrome at 13 months and autism at 6 years old. Max has been receiving therapy services since he was 10 months old. (Fresno Bee -- Opinion)
Could Some Forms Of Mental Retardation Be Treated With Drugs? Oct 26, 2009
They found similar abnormalities in dendritic spine development seen in humans with some forms of mental retardation, such as fragile X syndrome. The mice also exhibited impaired learning and memory. (Science Daily)
Trembling hands and molecular handshakes Oct 24, 2009
Expansion of the triplet sequence beyond 200 copies leads to Fragile X Syndrome (FXS), which is the second most common cause of hereditary mental retardation after Down's syndrome. FXTAS itself is apparently triggered by a lack of the protein Pur-alpha. (EurekAlert!)
Systematic review of pharmacological treatments in fragile X syndrome Oct 13, 2009
Fragile X syndrome (FXS) is considered the most common cause of inherited mental retardation. Affected people have mental impairment that can include Attention Deficit and/or Hyperactivity Disorder (ADHD), autism disorder, and speech and behavioural disorders. (BioMed Central)
Brain Researchers Discover Molecule Responsible For Axonal Branching Sep 24, 2009
2, 2004) Using an animal model system, researchers have advanced our understanding of Fragile X Syndrome by successfully visualizing individual mutant neurons in an otherwise normal brain. They find that. (Science Daily)
Necessary Process In Forming Long-term Memory Identified Sep 10, 2009
The findings suggest the possibility of fragile X syndrome therapies. (Oct. (Science Daily)
Function Of Neglected Structure In Neurons Revealed After 50 Years Sep 9, 2009
As the next step, Oertner s team intends to investigate to what extent the ER-dependent process plays a role in patients with fragile X syndrome. This condition is one of the most common inherited cognitive disorders, marked by reduced intelligence, learning difficulties and attention deficits. (Science Daily)
Genetic marker linked to problem behaviors in adults with developmental disabilities Jul 22, 2009
It is not, however, linked to behavior problems in individuals with fragile X syndrome, pointing to the need for further research on genetic and other contributors to problem behavior in individuals with different developmental disabilities. . (EurekAlert!)
Earlier Testing Needed for Fragile X Syndrome Jul 21, 2009
The disorder, known as fragile X syndrome, is the most common inherited form of intellectual disability and is not apparent at birth ... "Awareness of fragile X syndrome has grown as a result of research, statements by professional organizations and advocacy," said Don Bailey, a fellow at RTI International and the study's lead author ... The researchers looked at more than 200 families of children with fragile X syndrome. (MEDLINEplus)
New Memories: Easy To Encode, Hard To Retain Jul 14, 2009
The findings suggest the possibility of fragile X syndrome therapies. (June 18, 2007) How accurate are recovered memories of childhood sexual abuse. (Science Daily)
Family history Jul 13, 2009
Children also are at higher risk if their fathers are older than 40 or if children have conditions such as epilepsy or Fragile X syndrome, which causes mental retardation, according to the Mayo Clinic. People with autoimmune diseases shouldn't be alarmed, Atladottir says. (USA Today)
Hormone Treatment Eases Post-surgery Distress In Children Jul 5, 2009
18, 2009) Over-the-counter melatonin medication can shorted the length of time it takes for children with autistic spectrum disorder, Fragile X syndrome or both to fall asleep at the beginning of the night. (Mar. (Science Daily)
Placebo Effects In Caregivers May Change Behavior Of Children With ADHD Jul 1, 2009
21, 2008) Fragile X syndrome is the most common hereditary form of mental retardation. Many children with FXS also suffer from attention deficit and/or hyperactivity disorder, which complicates social. (Science Daily)
Measuring intellectual disability Jun 24, 2009
Davis, CA Researchers from the University of California, Davis have developed a specific and quantitative means of measuring levels of the fragile X mental retardation 1 (FMR1) protein (FMRP), which is mutated in fragile X syndrome ... Fragile X syndrome is the most common form of inherited intellectual impairment ... Nearly one third of patients diagnosed with fragile X syndrome also have some degree of autism, and the mutation underlying fragile X syndrome is the most commonly known single... (EurekAlert!)
Capturing The Birth Of A Synapse: Mechanism Locking Two Neurons Found May 29, 2009
(June 14, 2008) A team of scientists has discovered new information about how Fragile X Syndrome interferes with signaling between the nucleus of neurons and the synapse, the outer reaches of the neuron where two. . (Science Daily)
New Tool Helps Researchers Identify DNA Patterns Of Cancer, Genetic Disorders May 20, 2009
21, 2009) A cure for debilitating genetic diseases such as Huntington's disease, Friedreich's ataxia and Fragile X syndrome is a step closer, thanks to a recent finding in plant DNA that has similarities to. (Mar. (Science Daily)
Small molecules might block mutant protein production in Huntington's disease May 4, 2009
CAG repeats are involved in several other neurodegenerative diseases, including Fragile X syndrome, the most common form of mental retardation, and myotonic dystrophy. While these genes are best known for the devastating effects of their mutated forms, their normal forms are essential for embryonic development, nerve function and other bodily processes. (EurekAlert!)
2009 college all-stars gifted all over Apr 29, 2009
Matthew Baum, a soon-to-be Yale University graduate whose research on Fragile X Syndrome may someday lead to better treatments for mental retardation, is a wrestler on the side and started a club for beer aficionados. Harvard chemistry major Allen Cheng, 20, who envisions a career as a physician-scientist, finds pleasure in kendo, a form of fencing based on the art of Japanese samurai swordsmanship. (USA Today)
Melatonin May Ease Sleep Problems in Autistic Children Apr 28, 2009
The study included 12 children, aged 2 to 15 years, with autism spectrum disorder, fragile X syndrome (FXS), or both. The participants were randomly selected to take melatonin or a placebo for two weeks. (MEDLINEplus)
Melatonin Helps Autistic Children Sleep Apr 17, 2009
Over-the-counter melatonin medication can shorten the length of time it takes for children with autistic spectrum disorder (ASD), Fragile X Syndrome (FXS), or both to fall asleep at the beginning of the night, according to a new study. Results of the study indicated that children who received over-the-counter melatonin treatments experienced significant improvements in total night sleep durations, sleep latency times, and sleep-onset times. (Newsmax)
Melatonin is an effective treatment for sleep problems in children with autism Apr 15, 2009
- A study in the April 15 issue of the Journal of Clinical Sleep Medicine determined that over-the-counter melatonin medication can shorted the length of time it takes for children with autistic spectrum disorder (ASD), Fragile X Syndrome (FXS), or both to fall asleep at the beginning of the night ... For a copy of the study, "The Efficacy of Melatonin for Sleep Problems in Children with Autism, Fragile X Syndrome, or Autism and Fragile X Syndrome," or to arrange an interview with an AASM... (EurekAlert!)
Suit: Sperm Bank Responsible for Girl's Disease Apr 11, 2009
The case was brought on behalf of a 13-year-old girl with fragile X syndrome, a common inherited form of mental retardation. While the judge dismissed several claims, he allowed others to move forward; the hashes out the legal details. (Fox News)
Disabilities not a reason to send a person to 'jail' Apr 3, 2009
Psychiatric patients and those with physical disabilities have been largely de-institutionalized over the past few decades, but those with developmental (or, if you prefer, intellectual) disabilities such as Down syndrome and Fragile X syndrome have, to a certain extent, been forgotten in the push for social justice and equality. While the vast majority of people with disabilities now live in the community - they are our family members, friends, co-workers, neighbours, fellow congregants, hockey... (Globe and Mail)
Blocked Enzyme Reverses Schizophrenia-like Symptoms Mar 21, 2009
They have significantly alleviated a wide range of abnormalities due to fragile X syndrome by altering only a single. . (Science Daily)
Plan Offers Guidance For Evaluating Menopause-like Condition In Girls And Young Women Feb 16, 2009
Women in families affected by Fragile X syndrome an intellectual disability resulting from an abnormality on the X chromosome are at increased risk for primary ovarian insufficiency. The unexpected loss of fertility that accompanies primary ovarian insufficiency can be emotionally devastating for many women, Dr. Nelson wrote. (Science Daily)
