Chemical Found In Plastics, Bisphenol A, Linked To Chemotherapy Resistance Oct 10, 2008
Researchers have suspected that BPA could play a role in cancer because of the chemical's structural similarities to a cancer-promoting compound called diethylstilbestrol (DES). But Ben-Jonathan's team found that BPA isn't exactly mimicking the action of DES.. (Science Daily)
Mammogram Screening Day In Langford Jun 19, 2008
DES (diethylstilbestrol) -The drug DES was given to some pregnant women in the United States between 1940 and 1971. (It is no longer given to pregnant women. (Marshall County Journal, SD)
A 'drug drought' for pregnant women Jun 4, 2008
A drug used for morning sickness from the 1940s through the early 1970s, diethylstilbestrol, or DES, caused cancer in the daughters of women who took it. Today, few pregnant women would sign up to test experimental drugs even if they were available, says Candy's doctor, Michael Greene, an obstetrician-gynecologist at Harvard Medical School and Massachusetts General Hospital. (USA Today -- News)
Why Do We Worry About the Least Important Causes of Cancer? Apr 16, 2008
Or take diethylstilbestrol, known as DES, a drug used to promote fertility in certain women until it was shown to cause genital cancers in a blast of publicity in 1971. Ultimately, fewer than one in 1,000 exposed women got these cancers. (Slate)
Why Synthetic Estrogens Wreak Havoc On Reproductive System Apr 3, 2008
Past research shows that exposure to the synthetic estrogen diethylstilbestrol (DES) alters the expression of HOXA10, a gene necessary for uterine development, and increases the risk of cancer and pregnancy complications in female offspring. The team sought to understand why a developing female fetus exposed to DES might develop uterine cancer and other problems years after exposure. (Science Daily)
Ovarian Cancer Risk Seen In DES Grand-Daughters Mar 19, 2008
NEW YORK - Women whose mothers were exposed to diethylstilbestrol (DES) in the womb appear to be at increased risk of developing ovarian cancer, researchers report in the journal Epidemiology. DES, a synthetic form of oestrogen, was introduced in 1941 as a drug that prevented miscarriage. (Planet Ark, United States)
Truth and rumours muddy plastics debate Feb 11, 2008
They settled on a chemical called diethylstilbestrol, better known today as DES. It did unexpected but horrible damage; the women who took it were mostly unharmed, but their children suffered health problems, particularly reproductive tract cancers at a very young age in "DES daughters.". But while drug companies experimented with DES, they were also testing an alternative called bisphenol A, or BPA for short. (National Post)
Is plastic making us fat? Jan 14, 2008
Scientists say years of research into a once-popular synthetic hormone - diethylstilbestrol (DES) - also bolsters their belief that chemical exposure during early development can affect weight later in life. DES was once given to women to prevent miscarriages until it was linked to cancer in female offspring. (Boston Globe)
Prenatal DES Exposure May Not Affect Male Fertility Oct 9, 2007
NEW YORK (Reuters Health) - Men exposed to the drug diethylstilbestrol (DES) before birth appear not to have reduced fertility or be less likely to father boys, researchers have found. DES, a synthetic form of estrogen, was introduced in 1941 as a drug that prevented miscarriage. (MEDLINEplus)
Diethylstilbestrol Sep 3, 2007
DES Exposure and Autoimmune Disease Risk. Animal studies show that DES causes an increased risk of autoimmune disease; human studies are conflicting although self-reports by patients show an increased risk. (Suite101.com)
OUR OPINION: State board makes right call on Senate proposal Aug 22, 2007
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Michael Torchia, Health Expert Launches Global Alert To The Chemical Link To Obesity Aug 10, 2007
Another compound invented during that era, diethylstilbestrol, turned out to be more powerful as an estrogen, so bisphenol A was shelved. until polymer chemists discovered that it could be polymerized to form polycarbonate plastic. (Yahoo News -- Press Releases)
Scientists issue warning on chemical Aug 3, 2007
In the newest animal study, the lead scientist, Retha Newbold of the National Institute of Environmental Health Sciences, said BPA caused reproductive tract damage similar to the anti-miscarriage drug DES (diethylstilbestrol), a synthetic estrogen that was prescribed to pregnant women from the 1940s until the late 1970s. The drug led to "DES daughters," who were born with reproductive defects that caused infertility and cancers. (Los Angeles Times)
Sexual problems of long-term cancer survivors merit more attention Jul 27, 2007
The registry tracks the medical history of patients with specific gynecologic cancers who may have been exposed to diethylstilbestrol (DES) or other synthetic hormones while still in their mother's womb. Most of the women had been treated with surgery or radiation therapy when they were in their late teens or their 20s and had survived after their cancer diagnosis for more than 20 years. (EurekAlert!)
To detect cervical cancer, Pap is still the best test Jun 4, 2007
- Yearly at any age with either test if you have risk factors such as diethylstilbestrol (DES) exposure before birth, HIV infection or a weakened immune system. - Every two to three years with either test beginning at age 30 if you've had three normal Pap test results in a row. (Poughkeepsie Journal)
Birth control pill FAQ: Benefits, risks and choices May 22, 2007
Lessons learned from women who took diethylstilbestrol a synthetic estrogen that was later linked with cancer to prevent miscarriage in early pregnancy suggest that such exposure should be minimized. Once you learn that you're pregnant, stop taking the birth control pill. (MayoClinic.com)
Eating Beef in Pregnancy Linked to Reduced Sperm in Adult Sons Mar 29, 2007
Although the U.S. banned the growth promoter diethylstilbestrol (DES) for use in cattle in 1954, other hormones such as estradiol, testosterone, progesterone, and the synthetic hormones zeranol, trenbolone acetate, and melengestrol continue to be used, Dr. Swan said. Because residues of the chemicals persist after slaughter, the FDA has regulated their use, defined as "acceptable daily intake." In Europe, the use of these natural and synthetic hormones has been banned since 1988. (MedPage Today)
* Hormone-treated beef tied to sperm woes Mar 29, 2007
The first synthetic hormone, diethylstilbestrol, or DES, was formulated in 1933. In 1947, it was approved for use by pregnant women to prevent miscarriages. (Taipei Times, Taiwan -- World)
Mom's Diet May Affect Son's Sperm Count Mar 28, 2007
In 1979 the FDA did withdraw approval of the use of diethylstilbestrol (DES), the first synthetic hormone, in cattle. The European Union banned the use of growth promoters in cattle in 1988. (Click2Houston, TX)
Gardasil too new to know future risks Mar 6, 2007
In the 1950s we thought that Diethylstilbestrol was a true breakthrough in preventing miscarriage. It took a generation for us to realize that we had triggered an epidemic of ovarian cancer and infertility in the daughters born to those women who had used this drug. (Atlanta Journal-Constitution)
Florida considers HPV shot Feb 23, 2007
DES, or diethylstilbestrol, was a synthetic form of estrogen, prescribed from 1928 until 1971 to help women who had a problem with miscarriages in the past or premature deliveries. The use of DES declined in the 1960s after studies showed that it might not prevent pregnancy complications. (Naples Daily News)
