New pap test guidelines: start later, have fewer Nov 21, 2009
The new guidelines apply to healthy women, Waxman said, excluding for instance, those who have compromised immune systems, have HIV or who were exposed to diethylstilbestrol, or DES, in the womb. Those who've gotten the new HPV vaccine are urged to follow the guidelines. (FOX19.com, OH)
Disrupting Male Fertility Nov 18, 2009
Volle et al. The orphan nuclear receptor small heterodimer partner mediates male infertility induced by diethylstilbestrol in mice ... 7, 2006) So-called "DES daughters," born to mothers who used the anti-miscarriage drug, diethylstilbestrol during pregnancy, are at a substantially greater risk of developing breast cancer compared to women. (Science Daily)
Screening Guidelines For Breast, Cervical And Colorectal Cancers Redefined Oct 28, 2009
exposure to diethylstilbestrol (DES) before birth. Human Immunodeficiency Virus (HIV) infection. (Science Daily)
Estrogen Plays Surprise Role in Breast Cancer Treatment Aug 20, 2009
"The history of treating patients with estrogen goes back to the 1940s when physicians started to treat patients with advanced breast cancer with diethylstilbestrol or DES [a synthetic estrogen]," explained Dr. Matthew Ellis, a professor of medicine at Washington University School of Medicine, an oncologist with the Siteman Cancer Center in St. Louis and a co-author of the study. "The ancient literature is full of grainy photographs with lung metastases or local, advanced breast cancer or bone... (MEDLINEplus)
Aging well starts in womb, as mom's choices affect whole life Jul 1, 2009
That's why, doctors believe, many babies exposed before birth to a drug called DES, or diethylstilbestrol, later developed rare cancers or fertility problems, Taylor says. Doctors stopped prescribing DES, which had been used for decades to prevent miscarriages, in 1971. (USA Today -- News)
Androgen Deprivation in Prostate Cancer — Step by Step Jun 16, 2009
1 By 1966, when Huggins won the Nobel Prize in Physiology or Medicine for this work, many clinicians assumed that castration or treatment with diethylstilbestrol prolonged life and in some instances was curative. The Veterans Administration Cooperative Urological Research Group (VACURG) trials conducted in the 1960s tested this hypothesis. (New England Journal of Medicine)
The Case Against Animal Testing Apr 20, 2009
The Diethylstilbestrol Tragedy. One of the most well-known cases of animal tests proving fatally unreliable was in the study of Diethylstilbestrol (DES), a synthetic hormone for women. (Suite101.com)
The chemical in your baby's bottle Mar 23, 2009
BPA was originally synthesized in 1891; in the 1930s it was considered for pharmaceutical use because of its estrogenic properties but was abandoned when diethylstilbestrol (DES) was found to be a more potent synthetic estrogen. DES was prescribed to at least 2 million women to prevent miscarriage under the assumption that during pregnancy "some estrogen is good, so more must be better." By 1971, girls exposed to DES in the womb had developed an extremely rare vaginal cancer typically found in... (Boston Globe)
