Mechanism For Neuron Self-preservation Discovered Oct 25, 2009
Other groups had recently shown that mutations affecting PI(3,5)P2 production cause degeneration of excitable cells in both mice and humans, including mutants found in ALS and Charcot-Marie-Tooth disease. The team hypothesized that PIKfyve might be directing CaV1. (Science Daily)
Golgi Apparatus: Simple Explanation For How Baffling Structure Works Oct 17, 2009
(June 29, 2009) Stalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth disease. A mutant protein makes the microtubules too stable to perform their jobs, the. (Science Daily)
Father of man killed by Dartmouth police files suit Oct 2, 2009
In the lawsuit, the neurological condition was identified as Charcot-Marie-Tooth disease. Ramos said yesterday that he believes that his late wife, Anna, suffered from the same disease. (Boston Globe)
Police chief says officers given no choice in fatal shooting Aug 14, 2009
According to Denner, Ramos had been diagnosed with Charcot-Marie-Tooth disease, a hereditary neurological disorder that weakens a patient s leg muscles, among other symptoms. According to the National Institute of Neurological Disorders and Stroke website, the disease is one of the most common neurological disorders and is incurable. (Boston Globe)
Buckeyes Raise Awareness For Rare Disease Aug 6, 2009
And so it was that at a Damons restaurant near campus on a cloudy August afternoon, more than 60 Buckeyes came together to play video games and raise both money and awareness to fight Charcot-Marie-Tooth disease, a neurological order that has stricken quarterback s father. Coleman, a senior safety for the Buckeyes whose father Ron has battled breast cancer, said he was glad the members of the football team were able to give something back to the community. (Bucknuts.com)
Structural Biology Scores With Protein Snapshot Jul 13, 2009
Sanders and his team, who got interested in protein folding because of their work with DAGK, are now pursuing structural studies of misfolded membrane proteins that cause diseases including peripheral neuropathy (Charcot-Marie-Tooth Disease), diabetes insipidus and Alzheimer's disease. "For proteins that misfold because of mutations, we're using NMR tools to understand exactly what the mutations do to the proteins in terms of structure and stability," Sanders said. (Science Daily)
Microtubules Might Be Responsible For Some Cases Of The Neurological Disorder Charcot-Marie-Tooth Disease Jun 30, 2009
ScienceDaily (June 29, 2009) Stalled microtubules might be responsible for some cases of the neurological disorder Charcot-Marie-Tooth (CMT) disease, Tanabe and Takei report in the June 15, 2009 issue of the Journal of Cell Biology. A mutant protein makes the microtubules too stable to perform their jobs, the researchers find. (Science Daily)
Human Neurodegenerative Disorder Observed In Fruit Flies Jun 26, 2009
ScienceDaily (June 25, 2009) A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly that mimics key features of Charcot-Marie-Tooth disease, a common neurodegenerative disorder that strikes about one out of every 2,500 people in the United States ... When mutations in tyrosyl-tRNA synthetase were linked to Charcot-Marie-Tooth disease a few years ago,... (Science Daily)
Scripps research scientists observe human neurodegenerative disorder in fruit flies Jun 25, 2009
The new breed of insects may help society better understand and treat Charcot-Marie-Tooth disease. La Jolla, CA, June 24, 2009 -- A team of scientists from The Scripps Research Institute, Katholeike Universiteit Leuven, and the University of Antwerp, Belgium, among other institutions, has created a genetically modified fruit fly that mimics key features of Charcot-Marie-Tooth disease, a common neurodegenerative disorder that strikes about one out of every 2,500 people in the United States ...... (EurekAlert!)
New Clues About Mitochondrial 'Growth Spurts' Mar 5, 2009
It goes awry in one form of Charcot-Marie-Tooth disease, in which peripheral nerves deteriorate, and in other neurodegenerative diseases. How cells manage mitochondrial size and number remains unclear. (Science Daily)
Children to spread spring cheer (4) Feb 25, 2009
The daffodil giveaway is in the name of Charcot-Marie-Tooth disease and in honor of J.D. Griffith's daughter, Marah, who died at age 16 from CMT on Christmas Day 2001. Marah was instrumental in the conception of children giving daffodils to seniors. (Somerset Daily American, PA)
