Update On Aastrom's Cardiovascular Programs to be Presented At Transcatheter Cardiovascular Therapeutics Annual Meeting by Amit N. Patel, M.D. Sep 23, 2009
Cardiac Regeneration: -- U.S. Phase II IMPACT-DCM clinical trial (surgical delivery) * The IMPACT-DCM trial is the first trial to evaluate the surgical delivery of autologous cells directly into the human heart muscle for the treatment of congestive heart failure associated with dilated cardiomyopathy (DCM) in both ischemic and non-ischemic patients ... About Dilated Cardiomyopathy (DCM) ... The Company is currently conducting a Phase II clinical trial with dilated cardiomyopathy (DCM) patients... (Primezone Releases)
Mechanism Related To Onset Of Various Genetic Diseases Revealed Sep 21, 2009
20, 2009) Researchers at the Department of Biochemistry and Molecular Biology of Universitat Aut;noma de Barcelona (UAB) have revealed the process by which proteins with a tendency to cause conformational diseases such as amyotrophic lateral sclerosis, familial amyloidotic polyneuropathy, familial amyloidotic cardiomyopathy, etc. finally end up causing them. (Science Daily)
Pacemaker can't stop Red Lodge High spiker Sep 16, 2009
Lauren was diagnosed with cardiomyopathy, a disease that affects the heart's ability to pump blood. Cardiomyopathy can be caused by a viral infection. (Montana Standard, MT)
Roslindale's Meagan Foley's Marauders continue to fight cancer for the Jimmy Fund Sep 16, 2009
She was put on a waiting list for a new heart in March due to a cardiomyopathy that arose as a result of her childhood chemotherapy treatments. This is just another reason why [the walk] is so important to me, she said. (West Roxbury Transcript, MA)
Sudden Cardiac Death: Should Young Athletes Be Screened? Sep 11, 2009
He died that night, with an autopsy later revealing hypertrophic cardiomyopathy Robert Pratta / Reuters / Corbis ... Almost all cases of SCD occur in athletes with hereditary or congenital cardiovascular diseases like hypertrophic cardiomyopathy, a thickening of the heart ... The test returns accurate results for 98% of people with structural heart defects like hypertrophic cardiomyopathy. (Time.com)
Is red wine healthy for my heart? Sep 8, 2009
Any excess increases the risk of hypertension, obesity, liver damage, cardiomyopathy (a weak heart), high triglycerides and more. Based on the list of medications provided with your letter, your husband suffers from hypertension, depression and high cholesterol. (Erie Times-News, PA)
• Is drinking red wine really that heart healthy? Sep 5, 2009
Any excess increases the risk of hypertension, obesity, liver damage, cardiomyopathy (a weak heart), high triglycerides and more. To initiate drinking red wine or any other beverage containing alcohol for health reasons is inappropriate. (Burley South Idaho Press, ID)
Drinking is riskier than some think Sep 4, 2009
Heart cells are damaged, leading to cardiomyopathy, particularly in women. Several studies found that women who drink three to five drinks a day had 40 percent more breast cancers. (Honolulu Advertiser)
Aastrom Announces Transitions in Senior Management Sep 4, 2009
In May 2008, these activities were further strengthened when Mr. Dunbar focused the Company's clinical development programs on cardiovascular indications, including the U.S. Phase II IMPACT-DCM trial (dilated cardiomyopathy -- severe, chronic heart disease) and the U.S. Phase IIb RESTORE-CLI trial (critical limb ischemia) ... The Company is currently focused on cardiovascular regeneration through a Phase II clinical trial with dilated cardiomyopathy (DCM) patients (the IMPACT-DCM trial) and a... (Primezone Releases)
ASK DR. H: Guidelines changed for antibiotic usage Aug 27, 2009
Such heart conditions include mitral valve prolapse with orwithout heart murmur, rheumatic heart disease, calcified aortic valve stenosis, congenital heart conditions such as ventricular and atrial septal defects (holes between the right and left chambers) and hypertrophic cardiomyopathy (an abnormally thickened heart). These folks have hearts that already are exposed to bacteria from the mouth, which can enter their bloodstream during basic daily activities such as brushing or flossing. (Atlanta Journal-Constitution -- Health)
Takotsubo study published Aug 25, 2009
In an article appearing in this month s , Lahey Clinic Medical Center cardiologists publish their five-year study findings on takotsubo cardiomyopathy, a rare but increasingly diagnosed disease that mimics a heart attack mostly in menopausal women after they experience a stressful event, like the death of a loved one or job loss. Takotsubo, from the Japanese, means octopus trap. (Burlington Union, MA)
Nearly 400-Lb. Boy Collapses, Dies on Football Field Aug 25, 2009
"He had to have had some underlying heart problem," said Mankowitz, who suspects Anthony and his father had hypertrophic cardiomyopathy, the most common genetic heart condition that thickens the heart walls. It's also the most common cause of sudden death in athletes. (Fox News)
Special Stem Cells Build 'Biological Bypass' Aug 19, 2009
The findings suggest that the human heart contains a reservoir of CVPCs that can be used to create a biological bypass in patients with chronic coronary artery disease and ischemic cardiomyopathy, which results when arteries that supply blood and oxygen to the heart are blocked. "This therapeutic strategy could dramatically change the goal of cell therapy for the ischemic heart; prevention of myocardial injury would become the goal of cell therapy rather than the partial restoration of... (MEDLINEplus)
Boy's Broken Heart Tests Doctors, Family Aug 14, 2009
As Aaron struggled to survive in his first few years, his father lost his job and the Tanners lost their 27-month-old son Ethan suddenly to an unrelated and often undiagnosed heart condition called hypertrophic cardiomyopathy. "That was the biggest nightmare in the world... I was just a basket case with it for a while," Elizabeth said of the struggle. (ABC News)
Sudden death syndrome: Soccer's silent killer Aug 13, 2009
He suffers from hypertrophic cardiomyopathy - a disease that causes the heart muscle to expand significantly and is one of the most common causes of fatalities among young sporting professionals. Scott, now a successful manager, was 32 when he experienced extreme tiredness and breathing difficulties during a league game for the Leyton Orient. (CNN -- Health)
Tony Huesman; lived 31 years with heart transplant Aug 13, 2009
Mr. Huesman was diagnosed with cardiomyopathy while in high school ... Mr. Huesman s sister, Linda Huesman Lamb, was also stricken with cardiomyopathy and received a heart transplant in 1983. (Boston Globe)
Longest Surviving Heart Transplant Patient Dies From Cancer Aug 13, 2009
At the age of 16, Huesman was diagnosed with viral cardiomyopathy ... Cardiomyopathy causes the heart's muscle to thicken and become stiff ... Lamb also had cardiomyopathy. (W-USA News, DC)
Blows to the Chest Up Death Risk for Lacrosse Players Aug 12, 2009
Maron is director of the Hypertrophic Cardiomyopathy Center at the Minneapolis Heart Institute Foundation ... SOURCES: Barry Maron, M.D., director, Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, Minneapolis; Larry Chinitz, M.D., director, clinical cardiac electrophysiology, New York University Langone Medical Center, and associate professor, cardiology, NYU School of Medicine, New York City; Steve Stenersen, president and CEO, U.S. Lacrosse, Baltimore; Aug. 10, 2009,... (MEDLINEplus)
Obituaries in the news Aug 11, 2009
A native of Dayton, Ohio, Huesman was diagnosed while in high school with cardiomyopathy, a disease that progressively weakens the heart ... Hannah has cardiomyopathy, in which the heart muscle becomes swollen and sometimes fails. (Fresno Bee -- Nation)
Men with Angina Do Worse Than Women Aug 8, 2009
The findings should be interpreted cautiously, said Dr. Gregg C. Fonarow, a professor of medicine at the University of California, Los Angeles, and director of the Ahmanson-UCLA Cardiomyopathy Center. One reason is that a diagnosis of angina does not pinpoint the cause of the chest pain, he said. (MEDLINEplus)
• Seeking advice about alcoholic's bulging belly Aug 8, 2009
Hypertension (high blood pressure) and cardiomyopathy (damage to the heart muscle itself) are linked and can increase the risk of stroke or heart failure. The liver can be inflamed. (Burley South Idaho Press, ID)
Heavy lifting Aug 4, 2009
The die-hard jock was in congestive heart failure with cardiomyopathy - or a weakened heart muscle - as well as an enlarged heart. Murphy was stunned. (Boston Globe)
USC frosh Telfort has heart trouble, won't play Aug 3, 2009
Telfort, a 17-year-old Miami native considered one of the top linebacker prospects in the country, has been diagnosed with hypertrophic cardiomyopathy, a serious genetic heart condition that has figured prominently in the lives and deaths of many notable athletes in recent years ... Hypertrophic cardiomyopathy affects roughly one in every 500 people, according to the Mayo Clinic, and is the top cause of sudden heart-related death in people under 30 years old. (SportsIllustrated.CNN -- NCAA Football)
Transplants: Your Stories Aug 1, 2009
I had cardiomyopathy, which meant my heart was four times bigger than it should have been. Luckily I was only on the transplant list for three days. (BBC News -- Health)
Gene Cause of Cardiomyopathy in Box... Jul 28, 2009
Gene Cause of Cardiomyopathy in Boxer Dogs. Gene Cause of Cardiomyopathy in Boxer Dogs ... Many large breeds of dogs, particularly boxers, suffer from a serious and sometimes fatal heart condition: cardiomyopathy. (Suite101.com)
Promising First-in-class Drug Candidate For Genetic Protein-misfolding Disease Jul 24, 2009
In the case of TTR amyloid cardiomyopathy, amyloid fibrils infiltrate the heart, leading to heart dysfunction ... Wild-type (normal) TTR can also form amyloid fibrils, particularly in the elderly; approximately 15 to 25 percent of individuals over the age of 80 have demonstrable deposition in the heart leading to a cardiomyopathy. (Science Daily)
Novel Gene Found For Dilated Cardiomyopathy Jul 22, 2009
ScienceDaily (July 22, 2009) Researchers in the Heart Institute at Cincinnati Children's Hospital Medical Center have discovered a novel gene responsible for heart muscle disease and chronic heart failure in some children and adults with dilated cardiomyopathy (DCM) ... The study was funded by grants from the National Institutes of Health, the Children's Cardiomyopathy Foundation and the Abby Glaser Children's Heart Fund ... Dr. Tobwin is co-author of another study in the same issue of JACC... (Science Daily)
Scripps research studies lead to a promising first-in-class drug candidate Jul 22, 2009
In the case of TTR amyloid cardiomyopathy, amyloid fibrils infiltrate the heart, leading to heart dysfunction ... Wild-type (normal) TTR can also form amyloid fibrils, particularly in the elderly; approximately 15 to 25 percent of individuals over the age of 80 have demonstrable deposition in the heart leading to a cardiomyopathy ... FoldRx's pipeline includes a program in advanced clinical development to treat genetic neurologic and cardiovascular disorders, Transthyretin (TTR) Amyloid... (EurekAlert!)
Back on course: Steele feeling fine, headed to Hall of Fame, ready to play Jul 19, 2009
Then came late 2005, when Steele first learned the true severity of her hypertrophic cardiomyopathy, a hardening of the walls of the heart. She soldiered on while coaching Montana to its first Big Sky Conference golf title and berth in the NCAA postseason in April 2006. (Missoulian, MT)
Gene Mutation Is Linked to Heart Muscle Disease Jul 17, 2009
Findings shed light on understanding of dilated cardiomyopathy ... WEDNESDAY, July 15 (HealthDay News) -- Gene mutations that cause heart muscle disease and chronic heart failure in some children and adults with dilated cardiomyopathy have been identified by researchers ... Dilated cardiomyopathy -- the most common cause of heart failure in young people and the most common reason for a heart transplant -- is a condition in which the heart becomes weakened and enlarged and is no longer able to... (MEDLINEplus)
Girl's damaged heart heals itself years after surgery Jul 16, 2009
Hannah was eight-months-old when she was diagnosed with cardiomyopathy -- an inflammation of the heart muscle that impairs the heart's ability to work properly--in 1994. Hannah's heart was failing and she needed a transplant. (Xinhuanet, China)
Two hearts make one grow well Jul 15, 2009
Hannah, now 16, suffered as a baby from severe heart failure due to cardiomyopathy, a problem with the muscle of the heart ... The report's co-author Victor Tsang, a consultant at Great Ormond Street children's hospital in London, noted the research was also useful in the development of temporary artificial hearts for children suffering from cardiomyopathy. (Sydney Morning Herald -- World)
The 'piggy-back heart' that helped save a little girl's life Jul 14, 2009
The original operation in 1995 saved Hannah's life because she had cardiomyopathy - a condition which made her heart double in size and risk giving out within a year ... " Professor Peter Weissberg, of the British Heart Foundation, said cardiologists have long wondered whether a heart which is failing because of cardiomyopathy might be able to recover if rested. "This seems to be exactly what has happened in Hannah's case in which the donor heart allowed her own heart to take a rest and recover.... (BBC News -- UK)
Medications can be used to treat heart failure Jul 13, 2009
Some of the more common causes of heart failure are coronary-artery disease, heart attack, hypertension, myocarditis (inflammation of the heart muscle) often caused by a virus, arrhythmias, faulty heart valves, cardiomyopathy and severe anemia. Still other contributing diseases include diabetes, emphysema, hyper-or-hypothyroidism and hemochromatosis. (Erie Times-News, PA)
Cardiac screening for teens available July 18 in Portland Jul 10, 2009
The medical examiner determined the cause of death to be cardiomyopathy, a disease of the heart muscle ... Heller's son David Heller died in 2005 at age 17 of undiagnosed hypertrophic cardiomyopathy, which Quinn Driscoll may also have had. (Longview Daily News, WA)
Guatemalan teen awaiting transplant dies Jul 2, 2009
But on Friday, he lost his battle with a condition called dilated cardiomyopathy, which made his heart too weak to pump blood. He was a very sick boy, said nurse Carol Hewitt, who cared for Juan for seven months. (Atlanta Journal-Constitution -- Metro)
Saving lives Jul 1, 2009
Since then Andy has been diagnosed with hypertrophic cardiomyopathy. It is the same heart condition Cameroon footballer Marc-Vivien Foe died of during the middle of an international game in 2003. (BBC News -- Health)
Did Jackson do too much? Jun 30, 2009
There are other, more rare factors that could contribute to a sudden death during or after exercise, including cardiomyopathy, a disease in which the heart muscle becomes inflamed and becomes more prone to disrupted rhythm. Screening tests would detect that condition and others. (MSNBC -- Health)
Arrhythmogenic Right Ventricular Cardiomyopathy Jun 25, 2009
Volume 360:2784-2786. Since this article has no abstract, we have provided an extract of the first 100 words of the and any section headings. (New England Journal of Medicine)
ADHD Drugs May Increase Kids' Ri... Jun 18, 2009
Careful evaluation for a family history of sudden death, serious rhythm abnormalities, heart muscle disorders (cardiomyopathy), or Marfan's syndrome. A physical exam, including assessment of blood pressure and heart rhythm. (Suite101.com)
Study links some ADHD meds to rare... Jun 17, 2009
Study links some ADHD meds to rare deaths - CNN.com. Study links some ADHD meds to rare deaths. (CNN -- Law)
Study links some ADHD meds to rare deaths Jun 16, 2009
Study: Stimulant meds, often used in ADHD, may have role in kids' deaths. Authors warn parents not to stop treating kids with ADHD; risk is low. (CNN -- Health)
Guatemalan in Atlanta awaits word on transplant Jun 6, 2009
Dr. Frank Stegall, a cardiologist at Redmond Regional Medical Center in Rome, told Gonzalez he had a chronically weak heart, or dilated cardiomyopathy. The organ pumps only 20 percent of the blood a healthy heart would, Stegall said. (CNN -- Health)
Stricherz gets assistance dog from Canine Companions Jun 5, 2009
Coupled with that, she has hypertrophic cardiomyopathy, which causes the muscle of one chamber of the heart to thicken. Stricherz is the daughter of JoAnn Casanova and Jeff Stricherz. (Madison Daily Leader, SD)
Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting May 29, 2009
Congestive heart failure or cardiomyopathy may occur after discontinuation of anthracycline therapy. For patients with a history of cardiovascular disease, or if the results of cardiac monitoring indicate possible cardiac injury, the benefit of therapy must be weighed against the risk of myocardial injury. (PR Newswire)
RSCI Announces World-Leading Stem Cell Science Advisory Board May 27, 2009
In May he saved a young cardiomyopathy patient with serious complications by developing a new multi-faceted comprehensive stem cell treatment procedure. Dr. Grekos treats pulmonary hypertension and fibrosis, heart and peripheral vascular diseases, and is the only doctor known to have a successful stem cell therapy for renal problems. (Yahoo News -- Press Releases)
Local doctor to offer free school physicals May 25, 2009
"One of the key health concerns for the student athlete is a heart condition called Hypertrophic Cardiomyopathy (HCM). It is a congenital condition which results in an asymmetric enlargement of the left ventricle, the heart s main pumping chamber. Under exercise conditions, the outflow tract of the left ventricle becomes blocked by the enlarged muscle, resulting in cardiovascular collapse and sudden death," said Dr. David Zahaluk, clinic director for Main Street Medical Care. Risk factors for... (McKinney Courier-Gazette, TX)
How to prevent cardiac death in kids May 23, 2009
Are you related to anyone with sudden, unexplained, and unexpected death before the age of 50 (including sudden heart attacks with no prior history, unexplained accidents, unexplained drownings, SIDS) Are you related to anyone who has been diagnosed with a sudden death-predisposing heart condition such as, but not limited to, hypertrophic cardiomyopathy or Long QT syndrome. (comprehensive list is available). (Atlanta Journal-Constitution -- Health)
Epigenetics: 100 Reasons To Change The Way We Think About Genetics May 21, 2009
(June 9, 2008) A new study shows that microinjection of RNA molecules into mouse embryos induces a hereditary form of cardiac hypertrophy that is similar to human hypertrophic cardiomyopathy. The research may. (Science Daily)
Woman Takes Brother's Health Care Fight to Twitter May 19, 2009
"Eric's very sick. He is in the hospital right now with severe dilated cardiomyopathy," she said. Veronica says Eric recently took a turn for the worse and has been hospitalized for the last week. (KLAS-TV)
Aastrom Reports Third Quarter Fiscal Year 2009 Financial Results May 9, 2009
U.S. Phase II cardiac regeneration clinical trial: -- On May 5, 2009 we reported preliminary findings from our U.S. Phase II IMPACT-DCM clinical trial to treat dilated cardiomyopathy (DCM) were presented at the International Society for Cellular Therapy annual meeting by the study's National Lead Investigator, Dr. Amit N. Patel ... A Phase II clinical trial with dilated cardiomyopathy (DCM) patients (the IMPACT-DCM trial) and a Phase IIb clinical trial with critical limb ischemia (CLI) patients... (Primezone Releases)
Mississippi mayor dies after primary loss May 8, 2009
His doctor testified at the time that he was in "end stage cardiomyopathy.". He had been acquitted in April 2007 on state charges related to the raid. (San Francisco Chronicle -- Crime)
Controversial mayor dies two days after loss May 8, 2009
His doctor testified at the time that he was in "end stage cardiomyopathy." She said she recommended a heart transplant, but Melton refused to get on a donor list. He and the bodyguard, Jackson police officer Michael Recio, were both acquitted in April 2007 on state charges related to the raid. (MSNBC -- Politics)
Melton mayoral timeline May 7, 2009
Court documents revealed Melton was in the end-stage of cardiomyopathy, a serious heart condition that prevents the heart from properly pumping blood. The documents also indicated Melton's cardiologist had recommended a transplant, but Melton declined. (The Clarion-Ledger)
Ailing Jackson mayor in hospital after primary loss May 6, 2009
Court documents released late last year said Melton was in end-stage cardiomyopathy. Melton's neighbor, A.D. Lewis, was standing by the ambulance when the mayor was loaded up. (USA Today)
Sernova Corp.: New Strategic Plan Apr 29, 2009
His research training and experience includes biochemical pharmacology, diabetes, oncology, inflammatory diseases (psoriasis, multiple sclerosis, surgical adhesions, Alzheimer's disease and rheumatoid arthritis), osteoarthritis, neurological diseases and cardiovascular conditions including ischemic heart disease, cardiomyopathy, hypertension and aneurysms. Dr. Toleikis will be presenting on the Corporation's behalf at the BioFinance Conference in Toronto on Wednesday, April 29, 2009. (CCNMatthews Press Releases)
Surgical Ventricular Reconstruction for Heart Failure Apr 28, 2009
1 However, none of them specifically address the coronary disease responsible for ischemic cardiomyopathy and myocardial infarction. Coronary-artery bypass grafting (CABG), which was first used to ameliorate. (New England Journal of Medicine)
National Occupational Therapy Month Apr 28, 2009
The title of Dr. Wang's grant is "Molecular Pathogenesis of Protein Surplus Cardiomyopathy." Other medical school investigators who are participating in the project include Drs. Doug Martin, Curt Kost and Huabo Su. (Sioux City Journal)
Reduce Suffering, Urge Heart Failure Patients and Caregivers Apr 28, 2009
Family members who look after people with heart failure are important in the overall picture of medical care, said Dr. Gregg Fonarow, director of the Ahmanson-UCLA Cardiomyopathy Center and associate chief of the UCLA Division of Cardiology at the University of California, Los Angeles. "We recognize that patients who do well have engaged family members," Fonarow said. (MEDLINEplus)
Want A Portuguese Water Dog? Find Out If One Is Right For You Apr 17, 2009
"We have a lot of recessive health problems that crop up like hip dysplasia, progressive retinal atrophy, juvenile cardiomyopathy, storage disease, which is a disease of the nervous system," she said. Because of their hair, owners have to brush them a few times a week, and get them groomed frequently. (W-USA News, DC)
Heart And Skeletal Muscle Inflammation: A 'New' Infectious Disease Of Atlantic Salmon Apr 15, 2009
In her doctorate, Kongtorp described the disease and compared the pathological findings to those of a number of known diseases such as pancreas disease (PD) and cardiomyopathy syndrome (CMS). Both field sampling and contact infection trials indicate that HMSI is a new disease caused by an unknown organism. (Science Daily)
Virus-Induced Myocarditis Prevented In Mice Apr 14, 2009
Moreover, the mice did not show any evidence of inflammatory cardiomyopathy. That is why Professor Gotthardt assumes contrary to previous hypotheses that the direct effects of the virus infection, and not the autoimmune response, primarily determine the disease process. (Science Daily)
Current Drug Can Treat Rare Heart Disorder Apr 13, 2009
12, 1998) The drug cyclosporin may be effective in treating hypertrophic cardiomyopathy (HCM), a heart disease cited as the most frequent cause of sudden death in young adults and young athletes, according to. . (Science Daily)
Cutler: "It's a dream come true" Apr 11, 2009
Tiana was suffering from dilated cardiomyopathy, which causes the heart to weaken and enlarge, disabling the heart's pumping system. As a result, Tillman changed the focus of his foundation from education to improving the lives of critically and chronically ill children. (BearReport.com)
'Faulty genes' Apr 10, 2009
Eventually a genetic test determined that the condition was a rare inherited heart disorder - arrhythmogenic right ventricular cardiomyopathy (ARVC). Claudia already knows she has passed the condition on to at least one of her three children. (BBC News -- Health)
