Cancer Drug Resistance: 'New' Estrogen Receptor Found To Be Key Player In Tamoxifen Resistance Oct 31, 2008
A second important insight is that the discovery could help explain why invasive lobular carcinoma the sub-type of breast cancer in which these findings were made may not respond as well to tamoxifen as perhaps other subtypes do, she says ... Invasive lobular carcinoma, which accounts for 15 percent of newly diagnosed invasive breast cancers diagnosed each year, appear under the microscope as long, very thin tumors actually a single stream of cancer cells that line up in a row ... That makes... (Science Daily)
Melbourne scientists hit on cancer treatment Oct 31, 2008
Cancerous melanoma and colon carcinoma cells survive because the body's internal mechanism for killing cancer cells known as apoptosis can no longer counteract dangerous mutations. Dr Clare Scott, who along with Professor Andreas Strasser and Dr Mark Cragg led the research team, said scientists hoped the entire treatment might be orally delivered sparing some patients the pain of chemotherapy. (The Age)
NCI Funded Clinical Trial to Study Treatment of Breast Cancer Using Cryoablation Oct 29, 2008
Oct. 28 /PRNewswire/ -- The American College of Surgeons Oncology Group (ACOSOG) which just initiated a National Cancer Institute (NCI) funded clinical trial entitled, "A Phase II Trial Exploring the Success of Cryoablation Therapy in the Treatment of Invasive Breast Carcinoma," has selected the Visica 2(TM) Treatment System from Sanarus Medical as the exclusive technology to be utilized in the cryoablation portion of this study. The ACOSOG study protocol (designated as Z1072) will evaluate not... (PR Newswire)
Early Trial Of New Multi-kinase Inhibitor Shows Impressive Activity In Thyroid Cancer Oct 28, 2008
4, 2000) New research published recently in the journal Thyroid shows that paclitaxel (Taxol) has significant clinical activity against anaplastic thyroid carcinoma (ATC). (June 6, 2006) Research has found a promising, novel biomarker that may be used to predict the survival of patients with advanced lung cancer and their response to treatment. (Science Daily)
"Breast Cancer: The Journey" Discussion | WUS... Oct 26, 2008
My 51 year old sister was diagnosed last week with ductal carcinoma which has spread to her pelvis and thigh ... My 51 year old sister was diagnosed last week with ductal carcinoma which has spread to her pelvis and thigh ... DCIS is Ductal Carcinoma In Situ, or cancer that is in the ducts only. (W-USA News, DC)
The Helicobacter pylori duodenal ulcer promoting gene, dupA in China Oct 25, 2008
H. pylori were isolated from gastric biopsies of patients with chronic gastritis, duodenal ulcer (DU), gastric ulcer (GU), or non-cardia gastric carcinoma ... Isolates from 360 patients including 133 with chronic gastritis, 101 with DU, 47 with GU, and 79 with non-cardia gastric carcinoma were examined. (BioMed Central)
Thallion's TLN-4601 Inhibits Mutated K-Ras Signaling in Cancer Cells Oct 24, 2008
The results also demonstrate that TLN-4601 inhibits the growth of wild-type and KRAS-mutated pancreatic carcinoma cell lines and modulates downstream signaling events subsequent to Ras activation in a dose-dependent manner. Mutated K-Ras is associated with 90 percent of pancreatic cancers, as well as being highly expressed in other cancers such as non-small cell lung cancer and colorectal cancer. (CCNMatthews Press Releases)
Chest Scans May Help Monitor Spread Of Head And Neck Cancer In High-risk Patients Oct 23, 2008
Developing a second, distant cancer (a metastasis or a new primary cancer) is an important factor affecting survival of patients with head and neck squamous cell carcinoma, which accounts for most head and neck cancers, according to background information in the article ... Yen-Bin Hsu, M.D., of Taipei Veterans General Hospital, Taiwan, and colleagues evaluated 270 screening chest CT scans performed over 42 months in 192 patients with head and neck squamous cell carcinoma ... "For patients with... (Science Daily)
Chest CT Scans Detect Spread of Head, Neck Cancers Oct 23, 2008
They evaluated 270 screening chest CT scans conducted over 42 months in 192 patients with head and neck squamous cell carcinoma, which accounts for most head and neck cancers ... "For patients with head and neck squamous cell carcinoma, chest diagnosis is crucial and may influence their treatment plan," they noted ... "In conclusion, chest CT is recommended for high-risk patients, especially every six months for the first two years during the follow-up period, although its role is controversial... (MEDLINEplus)
A family nurse practitioner's experience Oct 18, 2008
Nonetheless, she was diagnosed with infiltrating ductal carcinoma in March 2006 ... Nonetheless, she was diagnosed with infiltrating ductal carcinoma in March 2006 ... Nonetheless, she was diagnosed with infiltrating ductal carcinoma in March 2006. (Juneau Empire)
THINK PINK: 'Early detection saves lives and I am proud to help raise money ...' Oct 18, 2008
My diagnosis was a Stage 2 tumor with bilateral lobular carcinoma in situ. That means I had a pre-existing condition on both sides with cells that favored the growth of this cancer. (Florida Times-Union)
Genetic 'Fingerprint' Shown To Predict Liver Cancer's Return Oct 17, 2008
Unlike many cancers, hepatocellular carcinoma, a form of liver cancer, is often detected early ... However, a major obstacle to applying such methods to hepatocellular carcinoma, as well as other cancers, has been the technical requirements samples must be frozen, not preserved, or "fixed," in the chemical formalin ... Hoshida Y. et al. Gene expression in fixed tissues and outcome in hepatocellular carcinoma. (Science Daily)
Life with breast cancer: Head-to-toe truths Oct 17, 2008
"I have no plans for reconstruction," says Debbie Arkin, 49, of Tampa, Florida who had a double mastectomy to remove stage IIA invasive ductal carcinoma in 2006 and is featured on Health ... Dawn Reinhart, who learned she had stage IIB invasive ductal carcinoma at age 34, had a more difficult time. (CNN -- Health)
Not an advocate - MacAulay encourages women to have mammograms Oct 16, 2008
Eight years ago, Marcy was diagnosed with a ductal carcinoma, a type of breast cancer that develops in the breast's milk ducts. In Marcy's case, the cancer was in situ meaning it was a non-invasive cancer which had not spread to surrounding breast tissue. (Sleepy Eye Herald Dispatch, MN)
Kevin Foster, 39; was pitcher for Cubs Oct 15, 2008
He died in an Oklahoma City hospital Saturday of renal cell carcinoma, his brother, Mark, said. Mr. Foster spent seven years in the majors, pitching mostly with the Chicago Cubs. (Boston Globe)
Obituaries in the news Oct 15, 2008
He died Saturday in an Oklahoma City hospital after a six-month bout with renal cell carcinoma, his brother Mark Foster said. Foster was drafted by the Montreal Expos in the 29th round in 1987 as an infielder. (International Herald Tribune -- Technology)
Rangers prospect had heart condition Oct 15, 2008
He died in an Oklahoma City hospital Saturday after a six-month bout with renal cell carcinoma, brother Mark Foster said. FROM NEWS SERVICES. (San Diego Union-Tribune -- Sports)
Common Variant Increase Risk Of Most Common Form Of Skin Cancer By 170% Oct 15, 2008
14, 2008) Scientists at deCODE genetics have report the discovery of common versions of two single-letter variations in the human genome (SNPs) that confer risk of basal cell carcinoma (BCC), the most common cancer among people of European ancestry ... The paper, entitled Common variants on 1p36 and 1q42 are associated with cutaneous basal cell carcinoma but not with melanoma or pigrmentation traits, appears in the online edition of Nature Genetics ... 29, 2000) Smoking more than triples the... (Science Daily)
Two More Genes Linked to Common Skin Cancer Oct 15, 2008
The variations play no role in skin colour but people with both of them are nearly three times more likely to develop basal cell carcinoma compared with people without the changes, researchers from Iceland's Decode Genetics said on Sunday ... "Here we have two variants that have no impact on pigmentation and only affect the risk of basal cell carcinoma," Kari Stefansson, Decode's chief executive, who led the study, said in a telephone interview ... Basal cell carcinoma is the most common form of... (MEDLINEplus)
Ex-Wyeth researcher to lead Temple drug discovery team Oct 14, 2008
The five major Wyeth drugs for which he led the development are: Effexor and Pristiq, both antidepressants; Mylotarg, a Leukemia drug; Tygacil, a broad-spectrum antibiotic; and Torisel, a treatment for renal cell carcinoma. He led his team in identifying drug compounds with great potential, moving them through years of development and testing; and giving the compounds the quality and stamina necessary to survive through the challenging clinical trials and regulatory process, said Dr. Jerry... (Philadelphia Business Journal, PA)
New Properties Of Skin Stem Cells Oct 14, 2008
We re now investigating the part played by the stem cells in the wound-healing process and the development of basal cell carcinoma, the most common form of skin cancer. The stem cells examined by the present study are found in the skin s hair follicles, around which the cells are able to move depending on their stage of growth. (Science Daily)
Endoscopic Therapy May Offer An Alternative To Surgery In Patients With Esophageal Cancer Oct 14, 2008
In a retrospective study of a prospectively collected database conducted at the University of Chicago, Dr. Jennifer Chennat and her colleagues, under the direction of Dr. Irving Waxman, examined medical records of 48 patients who underwent CBE-EMR for the treatment of Barrett's esophagus with high-grade dysplasia or intramucosal carcinoma from August 2003 to May 2008 ... (May 31, 2006) Two new Mayo Clinic studies draw attention to the risk factors and possible genetic basis for Barrett's... (Science Daily)
Liver transplant patients highly vulnerable to cancer Oct 14, 2008
Last Updated: Tuesday 14 October 2008 07:45 GMT. by Published on October 12, 2008 - 0 comments. (TheMedGuru)
Aesthetic Results of Breast Surgery Can Be Improved Oct 14, 2008
Postoperatively, 21 of the tumors were confirmed to be ductal or lobular carcinoma in situ and 12 were invasive malignancies. Eight of the invasive cancers had a widespread intraductal component. (MEDLINEplus)
Prognostic parameters for recurrence of papillary thyroid microcarcinoma Oct 14, 2008
Papillary thyroid microcarcinoma (PTMC) is defined as a papillary thyroid carcinoma less than or equal to 1. 0 cm in size. (BioMed Central)
New devices push college students' buttons Oct 11, 2008
The question on the board was: basal cell carcinoma is common on the floor of the mouth, under the tongue and on the side of the tongue ... basal cell carcinoma most commonly appears on the lip), a small percentage of students answered true. (Lompoc Record, CA)
Drug Sorafenib Improves Kidney Cancer Outcomes Oct 11, 2008
"Sorafenib treatment appeared to improve outcomes among patients with advanced renal cell carcinoma, regardless of age," the authors wrote. "Additionally, side effects were expected, mild, and medically manageable. There was no notable difference in the frequency or severity of sorafenib-related toxicity between younger and older patients.". (MEDLINEplus)
Etheridge: Knowledge Gave Her Courage Oct 10, 2008
Kaufman was diagnosed in February 2001 and said she knows what it's like to get that phone call and hear the word "carcinoma" on the other end. "They say the scientific word, you're like -- that's cancer. Right?" Etheridge said. (CBS News -- Early Show)
Breast Reconstruction after Mastectomy Oct 10, 2008
A 45-year-old woman undergoes core needle biopsy of a breast mass 4 cm in diameter and fine-needle aspiration of a palpable axillary lymph node, the results of both of which are found to be consistent with invasive ductal carcinoma. . (New England Journal of Medicine)
Merkel-Cell Carcinoma Oct 10, 2008
Volume 359:1629-1631. Since this article has no abstract, we have provided an extract of the first 100 words of the and any section headings. (New England Journal of Medicine)
Faces of Survival: Jan Redd Oct 8, 2008
PERSONAL: After a mammogram in August 2001, I was diagnosed with invasive lobular carcinoma on Sept. 28, 2001. I had a lumpectomy followed by chemotherapy and radiation through June 2002. (The Augusta Chronicle)
Women Require Less Tobacco Exposure Than Men To Increase Colon Cancer Risk Oct 7, 2008
According to lead investigator Dr. Ludwig, "Because more of the relatives with positive findings smoked than did relatives without positive findings, our study suggests that smoking may have been responsible for the development of the precursor lesions, especially in light of the fact that smoking is a known risk factor for pancreatic carcinoma.". Adapted from materials provided by , via , a service of AAAS.. (Science Daily)
Urine Samples Could Reveal Breast Cancer Risk Oct 7, 2008
To explore the potential of urine screening for breast cancer, the authors obtained samples from 148 women, 44 of whom had a precancerous condition known as "atypical hyperplasia." Another 24 women had a cancer-risk elevating condition known as lobular carcinoma in situ (LCIS), while the rest of the patients were healthy. The research team concluded that elevated MMP-9 levels were associated with a fivefold increase in the risk for atypical hyperplasia and more than a 13-fold increased risk for... (MEDLINEplus)
Renewed call for tanning regulations Oct 7, 2008
This translated to an estimated 51 cases of melanoma, 294 cases of squamous cell carcinoma and seven deaths. The figures were higher in NSW and Queensland, where there were an estimated 12 and 14 deaths a year. (The Age)
H. Pylori bacteria may help prevent some esophageal cancers Oct 6, 2008
PHILADELPHIA Some bacteria may help protect against the development of a type of esophageal cancer, known as adenocarcinoma, according to a new review of the medical literature ... The review, published in the October issue of Cancer Prevention Research, a journal of the American Association for Cancer Research, found that people who had H. pylori strains carrying a gene called CagA were almost half as likely to get adenocarcinoma of the esophagus, a cancer that develops in the tube that... (EurekAlert!)
Hospital fined for needless tests Oct 6, 2008
In one of the cases, Dr Gopi Chand Ram, deputy director (health) in Bihar government was admitted to the hospital with tests suggestive of lymphoma and anaplastic carcinoma (both cancers) on June 11, 1999. On July 2 1999, he was referred to the Rajiv Gandhi Cancer Institute for treatment as Apollo didn't have adequate arrangements for treating cancer. (India Times, India)
Saliva Could Be Used To Detect Oral Cancer: Study Oct 5, 2008
squamous cell carcinoma, a form of oral cancer have a low five-year survival rate and a high rate of recurrence especially when the cancer has metastasized in lymph nodes located in the neck ... In the recent research, researchers have found a simple way to detect oral squamous cell carcinoma ... Researchers collected saliva samples from 64 patients with oral squamous cell carcinoma and 64 healthy patients. (TopNews)
Epstein-Barr Virus Protein Contributes To Cancer Oct 4, 2008
3, 2008) Researchers at the University of Toronto have shown that the EBNA1 protein of Epstein-Barr virus (EBV) disrupts structures in the nucleus of nasopharyngeal carcinoma (NPC) cells, thereby interfering with cellular processes that normally prevent cancer development ... The researchers conclude that there is "an important role for EBNA1 in the development of NPC, in which EBNA1-mediated disruption of PML nuclear bodies promotes the survival of cells with DNA damage." Since EBNA1 is... (Science Daily)
Breakthrough Optical Technology To Assess Colon Cancer Risk, Accuracy Oct 4, 2008
"Our premise is that since the lining of the large intestine -- rectum and colon -- is contiguous, if you see an abnormality in one part of the colon, then somewhere else in the colon you have a higher likelihood of harboring an adenoma [benign tumor] or carcinoma [malignant tumor]," said Hemant K. Roy, M.D., director of gastroenterology research at NorthShore University HealthSystem and the study's principal clinical researcher. "EIBS strengthens our premise thanks largely to the unique and... (Science Daily)
MRI Spots Early Breast Cancer In Mice Oct 3, 2008
2, 2008) A new magnetic resonance imaging procedure can detect very early breast cancer in mice, including ductal carcinoma in situ (DCIS), a precursor to invasive cancer ... They found that, when optimal methods were used, both DCIS and early invasive tumors "appeared clearly against a darker background." In those 12 mice, MRI was able to detect the sole relatively large tumor, 17 out of 18 small tumors that were less than 1 millimeter in size, and 13 out of 16 milk ducts that were distended... (Science Daily)
Saliva Proteins Could Help Detection Of Oral Cancer Oct 3, 2008
2, 2008) Clinicians could detect oral squamous cell carcinoma, a form of oral cancer, using a simple test that detects proteins in saliva, according to a report in the October 1, 2008, issue of Clinical Cancer Research, a journal of the American Association for Cancer Research ... Researchers collected saliva samples from 64 patients with oral squamous cell carcinoma and 64 healthy patients. (Science Daily)
ImClone: USD 70 per share proposal submitted by US-based large pharma; Takeda not mystery bidder Oct 3, 2008
One market investor said Erbitux has shown a benefit in NSCLC patients with squamous cell carcinoma, one indication which Lillys Alimta is currently not approved for. The source close to Takeda speculated that Celgene and Amgen could emerge as bidders for ImClone, however, said it was unclear whether it would make such synergistic sense from a product perspective. (FT.com -- Markets)
Spit Proteins Could Lead to Oral Cancer Test Oct 3, 2008
The latest findings focus on oral squamous cell carcinoma, which affects more than 300,000 people worldwide ... Researchers at UCLA's School of Dentistry collected saliva samples from 64 patients with oral squamous cell carcinoma and compared them with samples from 64 healthy patients. (MEDLINEplus)
Second lumpectomy for breast cancer reduces survival rates Oct 3, 2008
In the United States in 2008, an estimated 182,460 new cases of invasive breast cancer will be diagnosed, an additional 67,770 new cases of carcinoma in situ or "pre-cancer" will be discovered and 40,480 women will die from breast cancer. Designated by the National Cancer Institute, UC Davis Cancer Center cares for 9,000 adults and children each year from throughout the Central Valley and inland Northern California. (EurekAlert!)
Pitt research indicates new virus is culprit, not bystander, in deadly skin cancer Sep 23, 2008
PITTSBURGH, Sept. 22 University of Pittsburgh scientists are uncovering more evidence that a virus they recently discovered is the cause of Merkel cell carcinoma, an aggressive and deadly form of skin cancer ... "You can see the specific molecular steps." The team's current work could account for known risk factors for Merkel cell carcinoma such as UV exposure and ionizing radiation, which damage DNA and can lead to the viral mutations. (EurekAlert!)
No Tan is a Safe Tan Sep 20, 2008
"There is no controversy whatsoever about the presence of UV signature mutations in squamous cell carcinoma. You can see that the genes have been mutated in a way that UV directly caused it," he explained. "The melanoma connection to UV is probably indirect, so you wouldn't see the mutation directly in the melanoma cell even though the UV caused it.". (MEDLINEplus)
A new option to ameliorate quality of life of advanced gallbladder carcinoma? Sep 20, 2008
A new option to ameliorate quality of life of advanced gallbladder carcinoma ... A new option to ameliorate quality of life of advanced gallbladder carcinoma ... Reference: Qin TJ, Zhao XH, Yun J, Zhang LX, Ruan ZP, Pan BR. Efficacy and safety of gemcitabine-oxaliplatin combined with huachansu in patients with advanced gallbladder carcinoma. (EurekAlert!)
How to treat gastroesophageal adenocarcinom patients? Sep 18, 2008
Gastroesophageal adenocarcinomas have a poor prognosis ... A study of esophageal adenocarcinoma and squamous cell carcinoma patients diagnosed between 1996 and 1999 found that chemoradiation without surgery was most frequent therapy, although patients given chemoradiation followed by surgery had better survival compared to chemoradiation alone ... A research study to be published on 28 May 2008, in the World Journal of Gastroenterology investigates treatments received and factors that influence... (EurekAlert!)
Gastric cancer with 3 pathological features Sep 18, 2008
Primary carcinoma of the stomach is almost always adenocarcinoma or signet ring cell carcinoma and there are few reports of choriocarcinoma or neuroendocrine cell carcinoma. We report a patient with adenocarcinoma of the stomach combined with choriocarcinoma and neuroendocrine cell carcinoma ... Yasumitsu Hirano from Kanazawa University Graduate school of Medical Science described a patient with adenocarcinoma of the stomach combined with choriocarcinoma and neuroendocrine cell carcinoma. (EurekAlert!)
New 3-D X-ray Detects Breast Cancer Early Sep 18, 2008
For the experiment, researchers chose a particularly challenging specimen: a breast invaded by a lobular carcinoma (a diffusely growing cancer), the second most common form of breast cancer, which is also very difficult to visualize in clinical mammography. In this kind of sample, the determination of the extension of the cancer frequently fails in X-ray mammograms and ultrasonographs of the breast. (Newsmax)
New Tool To Speed Cancer Therapy Approval Available Sep 16, 2008
(May 31, 2007) The U.S. Food and Drug Administration (FDA) today approved Torisel (temsirolimus) for the treatment of a certain type of advanced kidney cancer known as renal cell carcinoma. Torisel was approved. (Science Daily)
Investigational Drug Shows Promise In Ovarian Cancer Sep 16, 2008
Michael Friedlander from Australia presented the results of an international collaborative trial which administered the drug to 35 patients with recurrent ovarian, fallopian tube or peritoneal carcinoma. At the ESMO Congress, he presented final results of the trial on behalf of his co-investigators. (Science Daily)
Registration statement including financial report Sep 16, 2008
AK lesions may progress to a form of skin cancer called squamous cell carcinoma, or SCC. We believe that our lead product candidate, PEP005 Gel for AK, once developed and, if approved for commercialization by the appropriate regulatory authorities, could offer patients an effective and well-tolerated treatment alternative for AK with a short, two-to-three day application regimen that could be performed by the patient at home. We are also developing a product candidate containing PEP005 for the... (Sydney Morning Herald)
RAD001 Combined with Sandostatin LAR(R) Depot and as Monotherapy Controls Growth of Rare Pancreatic Neuroendocrine Tumors Sep 14, 2008
In addition to pancreatic NET, RAD001 is being evaluated as a single agent or in combination with existing therapies in renal cell carcinoma, lymphoma, breast, gastric, lung and other cancers, as well as tuberous sclerosis. About Sandostatin LAR Depot Sandostatin LAR(R) Depot (octreotide acetate for injectable suspension) is a long-acting, injectable depot formulation of octreotide acetate, a somatostatin analogue that exerts similar pharmacologic effects on the human body as the natural hormone... (PR Newswire)
Illness forces band director to retire Sep 14, 2008
Reid was diagnosed with renal cell carcinoma (RCC) and was given approximately one year to live last month after he collapsed at band practice 10 days earlier ... Renal cell carcinoma (RCC) is the most common form of kidney cancer arising from the renal tubule. (Atmore Advance, AL)
Despite breast cancer diagnosis, women care for loved ones first Sep 14, 2008
By any measure, Camacho's diagnosis was devastating: infiltrating multicentric ductal carcinoma, a stage 2 B cancer that demanded aggressive chemotherapy, surgery and radiation, "the full nine yards.". CONTINUED 1. (OregonLive, OR -- News)
Platinum-Based Chemotherapy plus Cetuximab in Head and Neck Cancer Sep 11, 2008
Background Cetuximab is effective in platinum-resistant recurrent or metastatic squamous-cell carcinoma of the head and neck. We investigated the efficacy of cetuximab plus platinum-based chemotherapy as first-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck ... Methods We randomly assigned 220 of 442 eligible patients with untreated recurrent or metastatic squamous-cell carcinoma of the head and neck to receive cisplatin (at a dose of 100 mg... (New England Journal of Medicine)
Gaining A Better Understanding Of Kidney Diseases Sep 9, 2008
Cystic kidney disease, renal fibrosis, or renal cell carcinoma: Many diseases of the excretory organs are characterized by overproduction or on the contrary absence of characteristic proteins in the renal cells ... Pathologists also discovered renal cell carcinomas in some of the mice. (Science Daily)
Adult Cancer Therapies May Benefit Kids Sep 6, 2008
"The same gene that's mutated in 30 percent of medulloblastoma is mutated in 90 percent of basil cell carcinoma," Curran said. Curran is working on a drug that specifically targets the defective gene - and turns it off. (CBS News)
Now what? Dealing with a Breast Can... Sep 6, 2008
The most common kind is invasive ductal carcinoma, which accounts for 70 percent or more of all breast cancers, according to the Mayo Clinic (http://www. mayoclinic. (Suite101.com)
Grand Adventures Ranch Launches Holistic Equine Cancer Recovery Program Sep 6, 2008
Successful recoveries with the ranch's protocol have included horses with squamous cell carcinoma, sarcoids and melanomas ... squamous cell carcinoma. (Yahoo News -- Press Releases)
Down-staged liver cancer associated with good post-transplant outcomes Sep 5, 2008
For patients with liver cancer (also known as hepatocellular carcinoma), transplantation has been restricted to those who fit the Milan criteria ... Rather than expand the Milan criteria, researchers have suggested down-staging hepatocellular carcinoma to select for tumors with more favorable biology that will respond to treatment and do well following liver transplantation ... Article: "Excellent outcome following down-staging of hepatocellular carcinoma prior to liver transplantation: An... (EurekAlert!)
Cellular profile of the peritumoral inflammatory infiltrate in squamous cells carcinoma of oral mucosa :correlation with the expression of Ki67 and histologic grading. Sep 3, 2008
Cellular profile of the peritumoral inflammatory infiltrate in squamous cells carcinoma of oral mucosa :correlation with the expression of Ki67 and histologic grading ... Squamous cells carcinoma is the most important malignant tumor with primary site in the oral cavity and, given the great exposure of mucosa and lips to the etiologic factors of this neoplasm, its incidence is high ... Methods: In this study, oral mucosa samples of squamous cells carcinoma were analyzed, separated according to... (BioMed Central)
How much is one mans life worth? Sep 2, 2008
Neil Haines, aged 46, suffers from Metastatic Renal Cell Carcinoma, he was chosen to take a new drug called Sutent that reduced the size of his kidney tumour after only one full cycle of treatment. Mr Haines, who was born and lived in Ebbw Vale before moving to Epsom to work as a graphic designer, has since been told that NICE have made a decision to withdraw the drug because it costs too much. (WalesOnline)
Muscle invasive bladder cancer in Upper Egypt: the shift in risk factors and tumor characteristics Aug 30, 2008
In Egypt, where bilharziasis is endemic, bladder cancer is the commonest cancer in males and the 2nd in females; squamous cell carcinoma (SCC) is the commonest type found, with a peculiar mode of presentation. The aim of this study is to identify and rank the risk factors of muscle invasive bladder cancer (MIBC) in Upper Egypt and describe its specific criteria of presentation and histopathology. (BioMed Central)