Genetic links to fungal infection risk identified Oct 29, 2009
The findings have implications for people suffering from chronic mucocutaneous candidiasis (CMC), as well as more common infections like vaginal candidosis (thrush). The UCL-led research focused on patients from multiple generations of a large family who had suffered from serious recurrent fungal infections that proved lethal in some of those affected. (EurekAlert!)
Human Dectin-1 Deficiency and Mucocutaneous Fungal Infections Oct 29, 2009
We describe a family in which four women who were affected by either recurrent vulvovaginal candidiasis or onychomycosis had the early-stop-codon mutation Tyr238X in the -glucan receptor dectin-1. The mutated form of dectin-1 was poorly expressed, did not mediate -glucan binding, and led to defective production of cytokines (interleukin-17, tumor necrosis factor, and interleukin-6) after stimulation with -glucan or Candida albicans. (New England Journal of Medicine)
Infectious Causes of Irritable Bowe... Oct 19, 2009
In alternative medicine a systemic yeast infection (candidiasis) is often blamed for a variety of symptoms, but this is controversial. Candida has also been blamed for irritable bowel syndrome, especially the diarrhea-dominant form (IBS/D), but studies are sparse. (Suite101.com)
BDSI awarded grant from Walter Reed Oct 7, 2009
Currently, the drug, which is used to treat systemic fungal infections such as Esophageal Candidiasis and parasitic diseases such as Leishmaniasis, is delivered intravenously. Bioral is a way of encapsulating intravenously delivered drugs in a way that the medication is not damaged or affected by stomach acids and digestive enzymes. (Triangle Business Journal)
Once-daily Pill Effective As Multiple Dosings For Oral Yeast Infection In HIV/AIDS Patients Sep 18, 2009
Researchers found that a small tablet applied daily that sticks to the gum and dissolves inside the mouth with few or no side effects is a novel, convenient option for treating an infection called oral candidiasis (OC), which occurs in about one third to one half of HIV patients and up to 90 percent of AIDS patients. The study is believed to be the largest to date involving HIV/AIDS patients with OC. The infection is also common in patients suffering from many forms of cancer, especially those... (Science Daily)
UTSA professors win stimulus-backed grants Aug 11, 2009
He will use his grant to study biofilms formed by the fungus, which causes infections called candidiasis. Candidiasis can be life-threatening in hospital patients with suppressed immune systems. (San Antonio Business Journal, TX)
UCB's CIMZIA(R) (certolizumab pegol) Approved by the U.S. FDA for Adult Patients Suffering From Moderate to Severe Rheumatoid Arthritis May 14, 2009
Invasive fungal infections, including histoplasmosis , coccidioidomycosis, candidiasis, aspergillosis, blastomycosis, and pneumocystosis ... Among opportunistic infections, tuberculosis, histoplasmosis, aspergillosis, candidiasis, coccidioidomycosis, listeriosis, and pneumocystosis were the most common. (PR Newswire)
Sexually Transmitted Infections: Transistors Used To Detect Fungus Candida Albicans May 12, 2009
This yeast can cause anything from simple mycosis of the skin to complicated cases of candidiasis. It is much more commonly found in patients suffering from immunodeficiency, tumours, diabetes and lymphomas, among other diseases. (Science Daily)
HIV & AIDS Feb 7, 2009
Candidiasis is a common HIV-related infection. It causes inflammation and a thick white coating on the mucous membranes of your mouth, tongue (thrush), esophagus (Candida esophagitis) or vagina. (CNN -- Health)
