Bone Drugs Not Linked to Disorder Nov 13, 2008
The drugs are also used to treat other bone diseases as well as certain cancers. Drugs in the class also include Zometa by Novartis; Boniva, marketed by AG and PLC; and Actonel, marketed by SA and Co.. (Wall Street Journal)
Genetic disorder sheds light on enzyme's role in bone metabolism Nov 5, 2008
The authors conclude: "These findings may be pertinent to our understanding of the functions of cathepsin K inhibitors, which are currently being developed as drugs to treat metabolic bone diseases.. (EurekAlert!)
New Guidelines Double Amount Of Recommended Vitamin D For Young Oct 14, 2008
14, 2008) The American Academy of Pediatrics (AAP) is doubling the amount of vitamin D it recommends for infants, children and adolescents. The new clinical report, "Prevention of Rickets and Vitamin D Deficiency in Infants, Children, and Adolescents," recommends all children receive 400 IU a day of vitamin D, beginning in the first few days of life. (Science Daily)
Vitamin D A Key Player In Overall Health Of Several Body Organs, Says Biochemist Oct 14, 2008
13, 2008) Essential for life in higher animals, vitamin D, once linked to only bone diseases such as rickets and osteoporosis, is now recognized as a major player in contributing to overall human health, emphasizes UC Riverside's Anthony Norman, an international expert on vitamin D. ... (July 10, 2007) Many otherwise healthy children and adolescents have low vitamin D levels, which may put them at risk for bone diseases such as rickets. (Science Daily)
Lab rats are killing your children! Oct 13, 2008
The lab study alarm du jour says now that youve got your kids all slathered up in sun screen to protect them from skin cancer, theyre going to get rickets, bone diseases, and a host of other nasty things because they arent getting enough sunshine. Funny how we were all so much healthier before we started to panic every time a lab rat died of something. (Seacoast New Hampshire)
Vitamin D a key player in overall health of several body organs, says UC Riverside biochemist Oct 10, 2008
Essential for life in higher animals, vitamin D, once linked to only bone diseases such as rickets and osteoporosis, is now recognized as a major player in contributing to overall human health, emphasizes UC Riverside's , an international expert on vitamin D.. In a paper published in the August issue of the , Norman identifies vitamin D's potential for contributions to good health in the adaptive and innate immune systems, the secretion and regulation of insulin by the pancreas, the heart and... (EurekAlert!)
Dow: How Low Can You Go? Oct 8, 2008
The news comes a month after Forbes reported that Pfizer was shifting its research and development focus to more profitable areas such as cancer, Alzheimers disease, and pain management and away from bone diseases like osteoporosis, liver disease, muscle disease, and obesity. Finally, could the secret to business success in these trying times be found in the Colonel's secret recipe. (Slate)
Indigestion may increase brittle bone risk Aug 19, 2008
However researchers warn that drugs used to treat heartburn and indigestion may in fact up the risks of brittle bone diseases like osteoporosis. A novel Canadian study showed that there was a 44 % higher chance of hip fracture among those people who used such drugs for 5 years. (HealthJockey.com)
UC Davis researcher gets $2M for stem cell research Aug 14, 2008
Doctors use adult stem cells from bone marrow to treat leukemia and other blood and bone diseases. Human embryonic stem cells, which are controversial because embryos are destroyed when the cells are extracted, and induced pluripotent stem (iPS) cells, formed by moving desired genes into adult stem cells, have more malleability than adult stem cells. (Sacramento Business Journal, CA)
Aurobindo Pharma gets USFDA approval for Cefazolin Injection Aug 12, 2008
Last week the pharmaceutical company had received US FDA approval to manufacture and market in US market, Alendronate Sodium tablets, used in the treatment of bone diseases. In recent stock recommendations, Religare Securities has advised its clients to buy shares of Aurobindo Pharma for short term as the technical charts show bullish candle pattern. (TopNews)
Cytochroma Closes $45 Million Series C Financing Jul 30, 2008
An estimated 70-90% of CKD patients have vitamin D insufficiency, which can lead to SHPT and resultant debilitating bone diseases. Mounting evidence continues to link vitamin D insufficiency with progression of CKD and death. (Canada Newswire)
Get A Little Sun This Summer -- It Could Help Save Your Life, Researcher Suggests Jun 19, 2008
18, 2008) As summer comes and people across America get ready to start slathering on the sunscreen, a note of caution is in order a little sunshine is good for you. Studies increasingly are suggesting the value of vitamin D often known as the sunshine vitamin, because that s one way you can obtain it in everything from bone metabolism to maintaining muscle strength, immune function, reducing hypertension and possibly even playing a role in prevention of cancer and autoimmune disease. (Science Daily)
Melbourne to host $100 million life sciences supercomputer Jun 18, 2008
"The world's largest life sciences supercomputer, based in Melbourne, will accelerate ground-breaking research in key areas such as cancer, cardio-vascular and neurological disease, chronic inflammatory diseases, bone diseases, diabetes and other life-threatening diseases," Brumby said. In addition to University of Melbourne scientists, researchers from other Victorian universities and institutes will have access to the supercomputer. (Computerworld Australia)
Melbourne snares $100m supercomputer Jun 18, 2008
"(It) will accelerate ground-breaking research in key areas such as cancer, cardio-vascular and neurological disease, chronic inflammatory diseases, bone diseases, diabetes and other life-threatening diseases," Mr Brumby said. "The $100 million super computer will focus on life sciences, utilising leading-edge research practices, such as using large databases of genetic information, complex models of analysis of human systems and hundreds of teraflops of computing power to increase computer... (Sydney Morning Herald -- Business)
Great Lakes Entrepreneur's Quest Grand Prize to be Awarded to Top Technology Company at Event in Lansing May 29, 2008
Today, his company, Velcura Therapeutics, is developing highly differentiated therapies for bone diseases. Bone diseases worldwide strike over 250 million individuals. (PR Newswire)
Cytochroma Appoints R. Richard Wieland II As CFO May 12, 2008
An estimated 70-90% of CKD patients have Vitamin D insufficiency, which can lead to SHPT and resultant debilitating bone diseases. Mounting evidence continues to link Vitamin D insufficiency with CKD progression and increased morbidity and mortality in CKD patients. (Canada Newswire)
Men Also at Risk for Osteoporosis May 12, 2008
According to the National Institutes of Healths Osteoporosis and Related Bone Diseases Natural Resource Center, the most common causes of secondary osteoporosis in men include low levels of testosterone (hypogonadism), alcohol abuse, smoking, gastrointestinal disease, hypercalciuria, and immobilization. The longer we live the more important bone health becomes, says noted expert Warren Levy, PhD, President, and CEO of Unigene Laboratories, a company on the forefront of the search for effective... (Newsmax)
Nutrition Q&A May 2, 2008
Osteoporosis, gradual loss of bone mass, is one of the most common bone diseases. Your diet can make a big difference in your bone strength. (Albany Democrat-Herald, OR)
Life in an Austrian Dungeon May 2, 2008
Lack of exposure to sunshine increases the risk of , which causes and other bone diseases including. Vitamin D malnutrition may also lead to chronic diseases such as high blood pressure. (Slate)
FORSTEO(R) Receives Approval from the European Commission for the Treatment of Glucocorticoid-Induced Osteoporosis Apr 4, 2008
(1) "Up to 50 percent of individuals on chronic glucocorticoid therapy will develop bone loss leading to an osteoporotic fracture,"(2) said Dr. Steven Boonen, professor of medicine at the Leuven University Centre for Metabolic Bone Diseases in Belgium ... Additionally, patients with bone metastases or a history of skeletal malignancies, and those with metabolic bone diseases other than osteoporosis, should not receive teriparatide. (PR Newswire)
Ranbaxy Labs launches Bonista Apr 3, 2008
One of the reasons could be that the majority of Indians have low vitamin D status and are on low dietary calcium which makes them prone to bone diseases As regards the burden of osteoporosis in the Indian scenario, 50 per cent women have osteoporosis and this translates to over 30 million in actual numbers. The Osteoporosis segment in India currently has a market size of around Rs 219 crore and grew more than 29 per cent in 2006-07. (India Times)
Same Process Discovered To Both Form Skeleton And Protect It For Life Mar 18, 2008
"In addition, normal Notch signaling appears to make bones stronger, but too much of it could result in osteosarcoma, the most common primary malignant bone tumor in children and teenagers. These studies suggest that well timed manipulations of a single process may represent new ways to fight two major bone diseases.". Brendan Lee, M.D., Ph. (Science Daily)
Global Osteoporosis Therapeutics Market to Reach US$11.1 Billion by 2010, According to New Report by Global Industry Analysts Feb 26, 2008
San Jose, California (PRWEB) February 26, 2008 -- Osteoporosis, the most common type of metabolic bone diseases, is an implacable epidemic growing rapidly in regions of North America, Europe, and Japan ... metabolic bone diseases. (Yahoo News -- Press Releases)
IOF hails WHO report and FRAXtm Web site as milestones in osteoporosis prevention and treatment Feb 22, 2008
World Health Organization Collaborating Centre for Metabolic Bone Diseases. University of Sheffield, UK.. (EurekAlert! -- Business News)
The Harm in Vitamin D Supplements Feb 13, 2008
The article reports that vitamin D deficiency puts children at risk for bone diseases such as rickets. In adults, vitamin D deficiency contributes to bone loss, causing conditions of osteopenia and osteoporosis. (Suite101.com)
Supercarrot to protect against bone diseases Jan 17, 2008
Medical Science News. Published: Wednesday, 16-Jan-2008. (News-Medical.net)
Life Expectancy Of Yeast Extended To 800 In Yeast Years, No Apparent Side Effects Jan 15, 2008
A study recently published in Cell (Issue 130, pages 247-258, 2007) reported that a mouse with a gene mutation first identified by Longo's group lived 30 percent longer than normal and also was protected against heart and bone diseases without apparent side effects. Longo's group next plans to further investigate life span extension in mice, and also is studying a human population in Ecuador with mutations analogous to those described in yeast. (Science Daily)
Vitamin D2 Is As Effective As Vitamin D3 In Maintaining Concentrations Of 25-hydroxyvitamin D, Study Suggests Jan 7, 2008
10, 2007) Many otherwise healthy children and adolescents have low vitamin D levels, which may put them at risk for bone diseases such as rickets. African American children, children above age nine and with. (Science Daily)
Protein That Controls Bone Growth Discovered Dec 23, 2007
22, 2007) A research team led by Dr. Pierre Moffatt of the Shriners Hospital for Children in Montreal and McGill University's Department of Human Genetics has uncovered the molecular mechanism by which the protein osteocrin controls bone growth -- a discovery that may have important implications for people suffering from bone diseases affecting skeletal growth. See also. (Science Daily)
Researchers discover protein that controls bone growth Dec 20, 2007
Discovery may lead to new treatments for bone diseases affecting skeletal growth. A research team led by Dr. Pierre Moffatt of the Shriners Hospital for Children in Montreal and McGill Universitys Department of Human Genetics has uncovered the molecular mechanism by which the protein osteocrin controls bone growth a discovery that may have important implications for people suffering from bone diseases affecting skeletal growth. (EurekAlert!)
Bad To The Bone: Shedding Light On Osteoporosis Nov 22, 2007
21, 2007) Ten million people in the United States are estimated to already have bone diseases, and almost 34 million more are estimated to have low bone mass, putting them at increased risk for osteoporosis, according to the National Osteoporosis Foundation. See also. (Science Daily)
Study Finds No Connection Between Vitamin D And Overall Cancer Deaths Nov 1, 2007
31, 2007) No relationship was found between vitamin D levels and the overall risk of dying from cancer, according to a study published in the Journal of the National Cancer Institute. However, higher vitamin D levels were associated with a decreased risk of colorectal cancer death. (Science Daily)
NIST Awards $2 Million to Velcura Therapeutics, Inc. for Innovative Technology R&D - Dual-Action Therapies for Bone Disease Sep 28, 2007
"These molecules are rapidly cleared from the blood stream, so these new drugs offer low systemic exposure, reduced off- target effects and extended time on target resulting in increased efficacy," according to Michael W. Long, PhD, president and CEO of Velcura Therapeutics, Inc. "This makes them effective agents for cancer patients and Velcura will start clinical trials I Multiple Myeloma patients for its first therapy, VEL- 0230, in early 2008." Velcura's ATP funding supports the development... (PR Newswire)
Old graveyard a first in Fla. Sep 24, 2007
But the remains also showed a race of people who cared for the weaker ones as evidenced by their careful burials, and a society capable of keeping alive, for a time, those born with fatal bone diseases, researchers said. Many FSU archaeologists have researched the skeletal cache, including a recent project that is looking at muscle markings on the bones to determine the ancient people's activities, Doran said. (Florida Today)
World's Top 10 Most Polluted Places Sep 20, 2007
As a result, local Azeris suffer cancer rates 22 to 51 percent higher than their countrymen and their children suffer from a host of genetic defects ranging from mental retardation to bone diseases. "As much as 120,000 tons of harmful emissions were released on an annual basis, including ," says Richard Fuller, founder of Blacksmith, an environmental health organization based in New York City. (Scientific American)
First Osteoporosis Study in Hip Fracture Patients Finds Once-Yearly Reclast(R) Prevents Additional Fractures and Improves Survival Sep 18, 2007
It is part of the Novartis HORIZON clinical trial program, one of the most comprehensive drug evaluation programs ever undertaken in the area of metabolic bone diseases involving 13,000 patients in more than 400 centers worldwide. Men and women between the ages of 50 and 98 who had experienced a recent hip fracture sustained with minimal trauma were randomized to receive a once- yearly infusion of Reclast or placebo within 90 days of undergoing surgery to repair the hip fracture and every 12... (PR Newswire)
Pregnancy & Vitamin D Sep 14, 2007
For general information on vitamin D: NIH Osteoporosis and Related Bone Diseases National Resource Center, Office of Dietary Supplements, NIH. Comments. (WHOI)
Kids' Bones At Risk From Low Vitamin D Jul 10, 2007
A new study shows more than half of otherwise healthy children have low vitamin D levels in their blood, which may put them at risk for bone diseases, like rickets. Vitamin D-fortified milk is the main source of vitamin D in the diet, but the vitamin is also produced within the body as a result of sunlight exposure. (CBS News)
Low vitamin D levels may be common in otherwise healthy children Jul 9, 2007
Many otherwise healthy children and adolescents have low vitamin D levels, which may put them at risk for bone diseases such as rickets. African American children, children above age nine and with low dietary vitamin D intake were the most likely to have low levels of vitamin D in their blood, according to researchers from The Childrens Hospital of Philadelphia. (EurekAlert!)
Taking care of your bones Jun 19, 2007
"About half of all women and one quarter of all men over age 50 will have an osteoporosis-related fracture in their lifetime," said Dr. John Jenkins, associate professor and director of the Metabolic Bone Diseases and Osteoporosis Clinic at the University of Mississippi Medical Center. The most disabling fractures occur in the hip and spine. (The Clarion-Ledger)
Scientists Probe Bones' Tiny Building Blocks May 27, 2007
In work that could lead to more effective diagnoses and treatments of bone diseases using only a pinhead-sized sample of a patient's bone, MIT researchers report a first-of-its-kind analysis of bone's mechanical properties. MIT researchers created this nanoscale map of the stiffness of bone. (Science Daily)
Study helps gene therapy work in obesity May 26, 2007
This study gives new insights into bone diseases, including osteoporosis, which contributes to more than 2 million fractures annually in the United States alone. We re really just starting to scratch the surface on how powerful leptin is in the body, and what gene therapy can do, she said. (Corvallis Gazette Times, OR)
Former Immunex Management Team Chosen to Head-Up CTI Subsidiary Aequus BioPharma, Inc. May 14, 2007
"While our initial focus will be directed toward follow-on biologics, we certainly believe CTI's discovery provides a platform which enables the rapid development of novel biotherapeutics so that patients can more readily benefit from the extreme pace of biomedical research we're experiencing in the post-genome era." Stewart Chipman is a biotech executive with over 15 years of experience in building and leading scientific teams focused on the discovery and development of novel human therapeutics... (PR Newswire)
A plea for a rare disease: Illness turns muscles into bone Apr 29, 2007
Lisa Danzer is stressing a practical reason for research into FOP: If the reason for the abnormal bone growth is discovered, it could guide the search for remedies for more common bone diseases, such as osteoporosis. And there's been progress: A year ago, researchers at the University of Pennsylvania School of Medicine found the so-called "skeleton key," a gene that, when mutated, triggers the bone formation process. (North County Times)
Cytochroma appoints co-founder Dr. P. Martin Petkovich as full-time Chief Scientific Officer Mar 12, 2007
According to the National Kidney Foundation, more than nine million North American patients suffer from moderate to severe CKD. Many develop vitamin D deficiency and secondary hyperparathyroidism which, if untreated, can cause debilitating bone diseases and increased patient morbidity and mortality. About Cytochroma Inc. Cytochroma (www. (Canada Newswire)
Antibiotics, painkillers sales at all time high Feb 14, 2007
76%, and musculo-skeletal system (bone diseases and muscle relaxants) at 24. Sanjeev I Dani, senior VP and regional director (Asia & CIS) Ranbaxy, opines: "Sustained economy growth rate has had cascading effect on the purchasing power in tier III, IV and rural areas. This has led to higher affordability for medicines in these towns. Apparently acute diseases still dominate in these areas leading to renewed demand for these categories. At the same time, the life style disorders/chronic therapies... (India Times, India -- Intl Business)
