DFMO may affect Barrett's esophagus Nov 17, 2008
The single-arm study included 10 patients with Barrett's esophagus and low-grade dysplasia ... "DFMO warrants further evaluation as a chemopreventive agent in patients with Barrett's esophagus and mucosal dysplasia," Sinicrope said. (EurekAlert!)
New research finds markers for esophageal cancer before it develops Nov 4, 2008
Barrett's esophagus (BE) is a common precancerous condition of the lower esophagus ... Lead author Murray Resnick, MD, comments, "Identification of biomarkers capable of distinguishing the grade of Barrett's esophagus-associated dysplasia, as well as identifying patients who are most likely to progress to cancer, would be extremely valuable tools for both surgical pathologists and gastroentorologists.". (EurekAlert!)
Multi-Centre European Clinical Trial Shows Advanced Dysplasia and Early Cancer of Esophagus Cured With Combined Endoscopic Resection and Radiofrequency Ablation With HALO Ablation System Oct 20, 2008
In a plenary presentation entitled, "Stepwise circumferential and focal radiofrequency energy ablation of Barrett's esophagus with early neoplasia: First European Multi-centre trial" patients with the most advanced stages of Barrett's esophagus, dysplasia and early cancer, were staged with endoscopic mucosal resection and then treated with the endoscopic radiofrequency ablation using the HALO Ablation System ... Population-based studies estimate that Barrett's esophagus affects approximately six... (PR Newswire)
High School Football Notebook: Gateway's game with McKeesport talk of the WPIAL (Today) Oct 20, 2008
Summers, in his first season, has Barrett's esophagus, a disorder partly caused by stomach acid reflux. "I did some research and only 1 percent of the population has this disease. Unfortunately, I'm in that 1 percent," Summers said. (Pittsburgh Post-Gazette, PA -- Sports)
Endoscopic Therapy May Offer An Alternative To Surgery In Patients With Esophageal Cancer Oct 14, 2008
New research presented at the American College of Gastroenterology's 73rd Annual Scientific Meeting in Orlando evaluated the long-term efficacy of endoscopic mucosal resection, or EMR, in the treatment of patients with early stage esophageal cancer or Barrett's esophagus ... Patients with recurrent cancers had longer Barrett's esophagus segments and needed more treatments to achieve remission ... CBE-EMR Effective Approach for the Management of Barrett's Esophagus. (Science Daily)
Potential Non-invasive Optical Detection Of Pancreatic Cancer Oct 14, 2008
13, 2008) New research has evaluated the long-term efficacy of endoscopic mucosal resection, or EMR, in the treatment of patients with early stage esophageal cancer or Barrett's esophagus. Two separate studies. (Science Daily)
Heartburn Is Not Harmless Sep 21, 2008
This condition is known as Barrett's esophagus ... People with Barrett's esophagus are at a much higher risk of developing esophageal cancer. (Suite101.com)
CSA Medical, Inc., Is Set to Put the Freeze on Thoracic Disease Sep 9, 2008
The CSA System has been successful in treating esophageal cancer and Barrett's esophagus, a pre-cancerous disease caused by chronic acid reflux, in nearly 50 major U.S. healthcare institutions and comprehensive cancer centers. William Krimsky, MD, an interventional pulmonologist and intensivist at Franklin Square Hospital in Baltimore, first had the vision to use the CSA technology for airway and thoracic diseases. (PR Newswire)
Throat Cancer Increasing among White Americans Aug 28, 2008
The major risk factors for esophageal adenocarcinoma, and the condition that precedes this cancer - Barrett's esophagus -- are gastroesophageal reflux disease (GERD -- chronic heartburn) and obesity, especially abdominal obesity, Brown pointed out. "Increases in the prevalence of these risk factors may have contributed to the upward trend in incidence.". (MEDLINEplus)
Obesity raises risks of serious digestive health concerns Aug 20, 2008
One particular study found that accumulation of abdominal fat, as measured by the waist-to-hip ratio, may be the most important risk factor for the development of acid reflux and related complications such as Barrett's esophagus and esophageal adenocarcinoma. The authors also examined data on the effects of weight loss through diet or surgical methods on acid reflux disease. (EurekAlert!)
Pre-cancerous Condition Linked To Chronic Acid Reflux Faces Several Hurdles Aug 12, 2008
(May 31, 2006) Two new Mayo Clinic studies draw attention to the risk factors and possible genetic basis for Barrett's esophagus and esophageal cancer (adenocarcinoma). These studies will be presented Monday, May. (Science Daily)
Endoscopic Circumferential Ablation Promising For Barrett's Esophagus With High-grade Dysplasia Aug 5, 2008
4, 2008) A multicenter U.S. registry study examining the treatment of Barrett's esophagus (BE) with high-grade dysplasia (HGD) showed that in 92 patients treated with endoscopic circumferential ablation who had at least one follow-up biopsy session, 90 ... Barrett's esophagus is a condition where the lining of the esophagus changes because of chronic inflammation, generally due to gastroesophageal reflux disease (GERD) ... Barrett's esophagus itself has no specific symptoms, but this change can... (Science Daily)
UT Southwestern digestive specialists freeze out esophagus cancer with new therapy Jul 29, 2008
The Food and Drug Administration-approved cryoablation therapy helps Barrett's esophagus patients with dysplasia, a condition in which normal cells are transformed into potentially cancerous ones ... "Repeated treatments can actually help get rid of Barrett's esophagus with dysplasia and prevent the progression to cancer," said Dr. Sreenarasimhaiah, a gastroenterologist who specializes in endoscopic technology ... Barrett's esophagus can result from ongoing heartburn, which allows a constant... (EurekAlert!)
Precancerous Esophagus Disease Eliminated in 98.4% of Patients Treated With HALO Ablation System Jul 21, 2008
4 percent of patients having a precancerous condition of their esophagus called Barrett's esophagus were free of the disease 2 ... Barrett's esophagus develops as a result of chronic gastroesophageal reflux disease (GERD) and afflicts more than 3 ... In this clinical trial, eight U.S. centers enrolled 70 patients having intestinal metaplasia, which is the earliest stage of Barrett's esophagus. (PR Newswire)
Doctors burn off precancers caused by Barrett's esophagus Jul 21, 2008
Researchers are testing procedures to eradicate abnormal cells produced by a condition called Barrett's esophagus, which results when the esophagus is burned by stomach acid, says David Fleischer, a professor at the Mayo Clinic in Arizona. FORUM. (USA Today -- News)
Potential Remedies To Obesity And Its Health Threats May 23, 2008
A Prospective Study of Body Mass Index and Barrett's Esophagus. Investigators have found that women who are obese are at significantly increased risk of developing Barrett's esophagus (BE). (Science Daily)
Could Common Pain Killers Have A Role In Cancer Prevention? May 21, 2008
Investigators researched the cancer cells of Barrett's esophagus and exposed them to the dual combination as well and found it be highly effective in decreasing the number of any surviving cancer cells ... 6, 2007) Celecoxib, a nonsteroidal anti-inflammatory drug (NSAID), did not prevent cancer in patients with Barrett's esophagus in a placebo-controlled study, according to new research published in the April 4. (Science Daily)
New Technology Speeds Gastrointestinal Disease Diagnosis May 20, 2008
In another study, Dunbar and colleagues concluded that CLE was as effective as a biopsy in identifying precancerous cells in people with Barrett's esophagus, a condition that can often lead to esophageal cancer ... Patients with Barrett's esophagus can require several tissue biopsies, which are expensive, invasive and can cause bleeding, the researchers said ... The results suggest that CLE "improves diagnosis of Barrett's esophagus, and offers great promise for reducing the number of biopsies... (MEDLINEplus)
Radiofrequency ablation is effective treatment for dysplasia in Barrett's esophagus May 20, 2008
Public release date: 19-May-2008. Contact: Stephanie Crayton. (EurekAlert!)
Cholesterol Drugs Destroy Esophageal Cancer Cells Apr 22, 2008
"As yet, it is not possible to extrapolate from our laboratory studies to clinical scenarios, but the current data do suggest that any effects of statins taken by patients with esophageal cancer and Barrett's esophagus are possibly beneficial," the investigators note. Further examination of statins or other agents that inhibit the same signaling pathways that lead to the formation of esophageal cancer cells -- in experimental models or in clinical trials with patients -- should continue so... (Newsmax)
Chronic heartburn triggers cancer, other ills Apr 1, 2008
While it's not yet certain that will block cancer from ever forming, the studies are promising enough that specialists have begun debating how to better find at-risk patients, people who suffer a condition called Barrett's esophagus ... That last condition is called Barrett's esophagus, and sufferers are 30 times more likely than the average person to go on to develop esophageal cancer ... But Carroll is optimistic enough that this spring, Georgetown begins a study to see if it's worth doing... (MSNBC -- Health)
Reflux: A burning nighttime problem Apr 1, 2008
Chuttani warned that chronic reflux can lead to Barrett's esophagus, a pre-cancerous condition that can increase the chance of developing cancer by 30 to 40 percent. He tells his patients that they don't have to suffer and they can often ease some of the symptoms by making simple lifestyle changes. (CNN -- Health)
Greater Baltimore Committee lauds leading biotech executives Mar 19, 2008
The technology has shown promise in treating esophageal cancer and Barrett's esophagus, a condition that often progresses to esophageal cancer. Julie D. Suman won the Entrepreneurship award. (Baltimore Business Journal, MD)
Sensor Necklace Records When Pill In Swallowed, And Prompts Patient When It Is Time To Take Another Mar 8, 2008
28, 2005) A new camera-in-a-pill can help doctors diagnose and evaluate diseases of the esophagus including gastroesophageal reflux disease (GERD), erosive esophagitis and Barrett's esophagus (a. (Sep. (Science Daily)
SpectraScience, Inc. Retains Hayden Communications Feb 12, 2008
The WavSTAT and LUMA systems are currently approved by the FDA for detecting pre-cancer and cancer in the colon and cervix, and an application for detection in the throat ("Barrett's esophagus") is being tested. This news release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. (PR Newswire)
Recovery means uncovering a past buried for years Feb 3, 2008
Barrett's esophagus: This is a change in the cells of the esophagus that can lead to cancer. It's caused by esophageal reflux. (Daytona Beach News Journal)
Health Highlights: Jan. 27, 2008 Jan 29, 2008
A condition called Barrett's esophagus, marked by changes in the lining of the esophagus, often precedes cancer. Detection of Barrett's esophagus can help prevent cancer. (U.S. News & World Report)
Camera In A Pill To Check Your Insides Jan 25, 2008
Esophageal cancer often follows a condition called Barrett's esophagus, a noticeable change in the esophageal lining. Patients with Barrett's esophagus can be healed, avoiding the deadly esophageal cancer ... Only a small percentage of people who get Barrett's esophagus, about 5 percent to 10 percent, develop cancer. (Science Daily)
City incubator attracts CryMed Dec 17, 2007
CryMed is working with Dr. Mark Johnston of the National Naval Medical Center to develop a patented device using low-pressure liquid nitrogen to treat patients with Barrett's Esophagus, an ailment believed to be a precursor to esophageal cancer. CryMed President Tim Askew said in a news release CryMed's technology is "moving rapidly toward commercialization.". (Baltimore Business Journal, MD)
Fruits and raw veggies reduce the risk of cancer Dec 10, 2007
In another study from a team at Ohio State University patients with a condition known as Barrett's esophagus which often leads to esophageal cancer, were given black raspberries, also called blackberries or blackcaps, which are also rich in cancer-fighting compounds. The researchers fed 32 grams of freeze-dried black raspberries to women with Barrett's esophagus and 45 grams to men, every day for a six month period. (News-Medical.net)
Diet And Cancer Prevention: New Evidence For The Protective Effects Of Fruits And Veggies Dec 8, 2007
Black raspberries modulate markers of oxidative stress in patients with Barrett's esophagus. Black raspberries may protect against esophageal cancer by reducing oxidative stress in patients with Barrett's esophagus (BE), a pre-cancerous condition that usually arises due to gastroesophageal reflux disease, report researchers at The Ohio State University. (Science Daily)
Blackberries, Broccoli Sprouts Battle Cancer Dec 8, 2007
In the first study, Ohio State University researchers found black raspberries may protect against esophageal cancer by reducing the oxidative stress that results from Barrett's esophagus, a precancerous condition usually caused by gastroesophageal reflux disease ... People with Barrett's esophagus typically are 30 to 40 times more likely to develop esophageal cancer, which has a poor five-year survival rate of 15 percent ... The team gave 32 grams to 45 grams of black raspberries daily for six... (MEDLINEplus)
Is There An Anti-Cancer Diet? Dec 7, 2007
They decided to expand the study to high-risk patients with a precancerous condition in the esophagus called Barrett's esophagus. Those with the conditionhave a 30 to 40 times higher risk of getting esophageal cancer, Kresty says. (CBS News)
3-D Model Of Esophageal Cancer Created Nov 21, 2007
(May 31, 2006) Two new Mayo Clinic studies draw attention to the risk factors and possible genetic basis for Barrett's esophagus and esophageal cancer (adenocarcinoma) ... 6, 2007) Celecoxib, a nonsteroidal anti-inflammatory drug (NSAID), did not prevent cancer in patients with Barrett's esophagus in a placebo-controlled study, according to new research published in the April 4. (Science Daily)
Large Waistline Ups Risk of Barrett's Esophagus Sep 21, 2007
NEW YORK (Reuters Health) - Excessive abdominal fat appears to significantly increase the risk of Barrett's esophagus, a condition in which cells that line the esophagus become abnormal, which may progress to esophageal cancer, a study shows ... "In fact, these results may partially explain why men experience so much higher risk than women of developing Barrett's esophagus and esophageal (cancer)." ... Vaughan, of the Fred Hutchinson Cancer Research Center, Seattle, Washington, and colleagues... (MEDLINEplus)
Exeter area business briefs Sep 4, 2007
Technology to treat Barrett's Esophagus. People suffering from the potentially precancerous esophageal condition known as Barrett's esophagus will have access to a technologically advanced treatment through Seacoast Gastroenterology at Exeter Hospital ... The hospital's new Barrx Halo system allows for safe and minimally invasive removal of Barrett's esophagus. (Seacoast New Hampshire)
Heartburn Can Be a Sign of Serious Disease Sep 1, 2007
Left untreated, persistent heartburn/GERD symptoms can lead to severe complications such as esophageal strictures or a precancerous condition called Barrett's Esophagus. In rare cases, people with persistent heartburn/GERD develop esophageal cancer. (Health-Finder)
You can learn heart help in a hurry Aug 18, 2007
Over time, the persistent acid bath can cause normal skin-like cells in the esophagus to change into tougher, more acid-resistant cells of the type found in the stomach and intestine, a condition called Barrett's esophagus ... Adenocarcinoma of the esophagus, the cancer associated with Barrett's esophagus, is currently the most rapidly rising cancer in the United States, with a sixfold increase in cases during the past 30 years, according to the U.S. National Cancer Institute. (Globe and Mail)
Gastroesophageal Reflux Disease Aug 13, 2007
The result is called Barrett's esophagus. The significance of this is its relation to esophageal cancer. (Suite101.com)
Why Persistent Acid Reflux Sometimes Turns Into Cancer: New Clues Aug 12, 2007
In research published in July and August, scientists discovered that people with acid reflux disease, particularly those with a complication of acid reflux called Barrett's esophagus, have altered cells in their esophagus containing shortened telomeres, the ending sequences in DNA strands ... "The research supports why it is important to prevent reflux, because the more reflux you have and the longer you have it, the more it might predispose you to getting Barrett's esophagus. So you want to... (Science Daily)
Frost brings another life sciences company to Miami Jul 27, 2007
SafeStich is an early-stage company specializing endoscopic and minimally invasive surgery for gastroesophagel reflux disorder and excision of Barrett's esophagus. The company is also developing techniques for hernia repair and natural orifice transesophageal surgery. (South Florida Business Journal, FL)
Body Parts -- The esophagus: A portal May 27, 2007
However, the changed tissue, called Barrett's esophagus, is at a higher risk of becoming cancerous. Heartburn in a pregnant woman can mean something quite different: that the baby will be born with a full head of hair. (North County Times)
New Approach To Treating Precancerous Esophagus Condition May 25, 2007
The new procedure is being tested in patients with Barrett's esophagus, a condition associated with the continued reflux of stomach acids into the lower esophagus that can damage its lining over time ... There are currently two main treatments for Barrett's esophagus with high grade dysplasia ... "This approach has the potential to dramatically alter the way we treat patients with Barrett's esophagus.". (Science Daily)
Presentation of Long-term Results for Treating Barrett's Esophagus with HALO Ablation System May 21, 2007
Barrett's Esophagus Eliminated in 98 ... 4% of patients with Barrett's esophagus treated with the HALO Ablation System have no residual Barrett's esophagus tissue after a follow up period of more than two and a half years ... The presentation of these long-term clinical trial results was made at the Digestive Disease Week (DDW) meeting this week, an international meeting of more than 16,000 gastrointestinal physicians and researchers, held in Washington D.C. Barrett's esophagus is a... (PR Newswire)
Celecoxib Does Not Prevent Cancer In Barrett's Esophagus Patients Apr 7, 2007
Celecoxib, a nonsteroidal anti-inflammatory drug (NSAID), did not prevent cancer in patients with Barrett s esophagus in a placebo-controlled study, according to new research published in the April 4 Journal of the National Cancer Institute. The incidence of Barrett s esophagus a precancerous change in the lining of the esophagus that increases the risk of developing esophageal cancer is on the rise in the United States. (Science Daily)
Light-based Probe 'Sees' Early Cancers In First Tests On Human Tissue Mar 29, 2007
Wax and his former graduate student John Pyhtila reported in the March 2007 issue of Gastrointestinal Endoscopy that their fiber-optic device reliably differentiated between healthy and precancerous digestive tissue taken from the stomach and esophagus of three patients known to have a precancerous form of a condition called Barrett's esophagus. In less than a second, their fa/LCI-enhanced version of an endoscope, instruments used to visualize internal organs, provided the clinical information... (Science Daily)
Early Cancers 'Seen' By Light-Based Probe Mar 28, 2007
Wax and his former graduate student John Pyhtila reported in the March 2007 issue of Gastrointestinal Endoscopy that their fiber-optic device reliably differentiated between healthy and precancerous digestive tissue taken from the stomach and esophagus of three patients known to have a precancerous form of a condition called Barrett's esophagus. The researchers said that in less than 1 second, their fa/LCI-enhanced version of an endoscope, instruments used to visualize internal organs, provided... (Click2Houston, TX)
Blockers not a cure Mar 27, 2007
A: Yes, but let me assume that you've been tested by a gastroenterologist and are free of serious conditions, including cancer, Barrett's esophagus or ulcers. With that, I can discuss heartburn and reflux (GERD), and what I say may surprise you. (Shoals TimesDaily)
Berries May Give Anti-Cancer Boost Mar 27, 2007
Based on the findings, the scientists have begun tests in people with Barrett's esophagus (a condition of the esophagus that increases risk of esophageal cancer) and precancerous colon polyps. The results of those tests aren't yet available. (CBS News)
New Procedure Helps Prevent Esophageal Cancer Mar 9, 2007
" The condition is called GERD, which stands for gastroesophageal reflux disease. Hofmann's doctor, gastroenterologist Dr. Bob Ganz, said the valve at the top of her stomach leaks. That allows the reflux of acids from the stomach up into the throat. It is a problem plaguing about one in five adults. "About 20 million Americans, we think, have acid reflux daily," said Ganz. For five to 10 percent of them, years of reflux actually change the cells' lining the esophagus from squamous cells to... (WCCO.com, MN)
Aspirin Reduces Esophageal-cancer Risk In People With Most-aggressive Form Of Barrett's Esophagus Feb 28, 2007
Researchers at Fred Hutchinson Cancer Research Center have found that people with the most-aggressive form of Barrett's esophagus, a precancerous condition that can lead to esophageal cancer, may benefit the most from preventive therapy with aspirin, ibuprofen and other nonsteroidal anti-inflammatory drugs, or NSAIDs ... D., and colleagues in the Hutchinson Center-based Seattle Barrett's Esophagus Program, will be published in the Feb. 27 issue of PLoS Medicine, a freely available online journal... (Science Daily)
Heartburn Treatment May Increase Bile Reflux Feb 14, 2007
A new study may explain why individuals treated for acid reflux with proton-pump inhibitors (PPI) still experience reflux symptoms. Researchers from the Lynn Health Science Institute in Oklahoma City, OK, treated 15 individuals with significant complaints of heartburn, with either a PPI or with a placebo. (Science Daily)
Study Reports 70% of Barrett's Esophagus Patients Cured at One-Year Follow-Up in Multi-Center Study Feb 5, 2007
Feb. 5 /PRNewswire/ -- BARRX Medical, Inc. today announced that 70% of the patients enrolled in a multi-center clinical trial were free of a precancerous condition called Barrett's esophagus one year after treatment ... In the report titled, "Circumferential Endoscopic Ablation of Barrett Esophagus using a Balloon- Based System: One-Year Follow-up of 100 Patients," patients with Barrett's esophagus were safely treated with the HALO360 Ablation System ... Barrett's esophagus is present in more... (PR Newswire)
Esophageal Cancer Rates Climb With Obesity; Esophagectomy Found Safe In Obese Patients Feb 1, 2007
"The type of patient who currently develops esophageal cancer has changed dramatically in the last 20 years. Esophageal cancer used to be primarily squamous cell carcinoma found in people who drank alcohol and smoked excessively. In association with the horrendous epidemic of obesity in this country, we have seen a 350 percent increase of adenocarcinoma over the last 30 years. This is related to more gastroesophageal relux and Barrett's esophagus in these patients," says Mark Orringer, M.D.,... (Science Daily)
Gastro Esophageal Reflux Disease: Study Demonstrates Long-term Durability Of Endoscopic Procedure Jan 13, 2007
(May 31, 2006) -- Two new Mayo Clinic studies draw attention to the risk factors and possible genetic basis for Barrett's esophagus and esophageal cancer (adenocarcinoma) ... (April 28, 2005) -- A new camera-in-a-pill can help doctors diagnose and evaluate diseases of the esophagus including gastroesophageal reflux disease (GERD), erosive esophagitis and Barrett's esophagus (a pre-cancerous. (Science Daily)
