50 millionth unique chemical substance recorded in CAS Registry Sep 11, 2009
Novel analgesic marks major milestone in scientific discovery ... The recently registered substance is a novel arylmethylidene heterocycle with analgesic properties. (EurekAlert!)
Cumberland Pharmaceuticals launches injectable ibuprofen Sep 10, 2009
The introduction of IV ibuprofen should allow anesthesiologists to achieve improved pain control with less opioid analgesic medication, thereby improving patient satisfaction, said Dr. Paul White, an anesthesiologist at the University of Texas Southwestern Medical Center in Dallas. The use of IV ibuprofen can help reduce opioid-related side effects, and Caldolor is the first IV analgesic with antipyretic and anti-inflammatory properties. (Nashville Business Journal, TN)
UK addiction warning for pain drugs Sep 5, 2009
It has been reported that 30,000 people have become addicted to medicines containing codeine - an effective analgesic which is combined with other painkillers such as paracetamol for sale by the pharmacist. But MPs have warned this figure could be the tip of the iceberg. (BBC News -- Health)
It's Not All In Your Head: Descending Neural Mechanisms Of Placebo-induced Pain Control Aug 30, 2009
The research, published by Cell Press in the August 27th issue of the journal Neuron, provides fascinating mechanistic insight into how and why simply expecting that a treatment will reduce pain can act as an effective analgesic. See also. (Science Daily)
Marine biomedicine researchers decode structure of promising sea compound Aug 29, 2009
In pharmacological tests conducted at Creighton University, Hoiamide A was shown to interact with the same important therapeutic target as analgesic, antiarrhythmic, antiepileptic and neuroprotective drugs. This is Scripps Institution of Oceanography at UC San Diego post-doctoral researcher Alban Pereira. (EurekAlert!)
Social Saviors, a Special Section on Pain, and Other Stories from MIND Aug 27, 2009
As the articles show, a feeling of reward can have an analgesic effect. Does that mean the pleasure gained from learning about how the mind works can count. (Scientific American)
MIND on Pain: The Psychology of Pain Aug 27, 2009
In the case of my elderly patient, my reassurance that the treatment would not significantly worsen his pain because he could stop me if it did produced an analgesic effect. In addition, reducing the man s fear enabled him to look forward to pain relief instead, and that positive expectation also eased his pain. (Scientific American)
Geriatric medicine comes to the zoo Aug 23, 2009
" The zoo's animal population has been getting younger overall due to recent births of sea lions, beavers and other species, but it still has a number of animals that might qualify for an AARP card. Around the corner from the tiger exhibit at the Highland Park zoo, Shiba, the 20-year-old female lion, and Juma, a male a year younger, move arthritically through their rocky exhibit and receive regular analgesic medication. The life expectancy for lions in captivity is 20 years. And up the hill at... (Pittsburgh Post-Gazette, PA)
Home Remedy Natural Relief for Sun ... Aug 22, 2009
St. John's Wort - in addition to its well-known anti-depressant action, St. John's wort is anti-inflammatory, a mild analgesic to soothe pain, and promotes more rapid healing. A tea can be made from the flowers and used as a compress. (Suite101.com)
Ibuprofen Rated Best for Pain of Broken Arms Aug 20, 2009
"The majority of children with simple arm fractures have pain at home significant enough to result in analgesic administration, and our study helps clinicians make an informed decision about what medication will work best for children with these injuries once they are sent home," said Drendel, who is also a pediatric emergency medicine specialist at Children's Hospital of Wisconsin. The study is in the Aug. 18 issue of the Annals of Emergency Medicine. (MEDLINEplus)
Ibuprofen is as effective as acetaminophen with codeine to treat pain in children with arm fractures Aug 18, 2009
"The majority of children with simple arm fractures have pain at home significant enough to result in analgesic administration and our study helps clinicians make an informed decision about what medication will work best for children with these injuries once they are sent home," points out Dr. Drendel. . (EurekAlert!)
Vicodin, Tylenol among drugs FDA scrutinizing Aug 15, 2009
"Now it's having its day in the spotlight, and that could dramatically change the analgesic market.". Acetaminophen is used primarily for pain relief and reducing fevers. (San Francisco Chronicle -- Science)
Results: Billy Mays died of heart disease Aug 8, 2009
Both are narcotic analgesic drugs and were, along with oxycodone another narcotic detected at therapeutic or subtherapeutic levels in Mays body. The autopsy also uncovered metabolites of alprazolam and diazepam, both benzodiazepine drugs, in Mays system at therapeutic or subtherapeutic levels and a level of ethyl alcohol consistent with a few social beverages. (Tampa Bay Business Journal, FL)
One out of three doctors choose Epocrates Rx for the iPhone Aug 3, 2009
Apps from the developer of clinical information and decision support tools include the prescription app, an over-the-counter information app, an infectious disease guide and a suite of tools to calculate IV drip rates, breast cancer risk, heparin dosing and opioid analgesic conversions, among other information. Some of the apps are free. (San Jose Business Journal, CA)
Types of Pain Medications Aug 2, 2009
Different Classes of Analgesics With Unique Mechanisms ... Doctors take into account a variety of factors, such as the cause of pain and the its severity, in order to choose the appropriate analgesic for a patient ... The nonsteroidal anti-inflammatory drugs (NSAIDs) are a familiar class of analgesics because of their availability as over-the-counter medications in drugstores. (Suite101.com)
Jody Johnson: Aloe vera A cheap trick Jul 30, 2009
Burns, as it stimulates skin growth and repair, acts as an analgesic; used for psoriasis and genital herpes with better results than the 1 percent cortisone cream. Constipation: A.V. juice or aloe latex is a powerful, natural laxative. (Belmont Citizen Herald, MA)
Drug use on the rise in Shippensburg Jul 27, 2009
Oxycontin is an opium derivative analgesic used for relief from moderate to high pain. Its often prescribed for cancer patients. (Carlisle Sentinel, PA)
Go easy on Paracetamol, it could hurt liver Jul 23, 2009
Doctors here say that the medicine if taken in the prescribed dose is the safest analgesic and fever-lowering medication, but in the West paracetamol poisoning is happening with the drug being abused, sometimes even intentionally. The drug has been under review as cases of acetaminophen-related liver injury are going up in the US. The risk accentuates if there is a combination of paracetamol with codeine (found in cough and cold medications). (India Times, India)
Texas doctors indicted on fraud charges Jul 19, 2009
Almost as potent as morphine, hydrocodone is a cough suppressant and analgesic for the treatment of moderate to severe pain, according to the U.S. Drug Enforcement Administration. The indictment alleged the Sharmas operated the Allergy, Asthma, Arthritis and Pain Centers on Cole Street in Webster and on Garth Road in Baytown. (KHOU.com, TX)
Developing A Safer Form Of Acetaminophen Jul 17, 2009
Miao et al. First Multigram Preparation of SCP-123, A Novel Water-Soluble Analgesic ... The study investigated the acute high dose ingestion of analgesics, nonsteroidal. (Science Daily)
Click to read:Pot No Longer Focus of Anti-Drug Campaigns Jul 16, 2009
The analgesic and sedative properties of marijuana are very helpful for chronic pain, insomnia and to relieve anxiety. It is a far better and safer medicine for older adults than most prescription drugs. (CBS News)
Legal Drugs Abused by Resident Coll... Jul 15, 2009
Known by the slang terms: "Oxy," "O.C.," or "Cotton." Oxycodone is an analgesic pain reliever that is widely popular among high school and college students. Oxycodone can react adversely with alcohol and other medications. (Suite101.com)
New words for Websters: Frenemy, webisode Jul 10, 2009
Naproxen (1971): an analgesic and antipyretic NSAID C14H14O3 often used in the form of its sodium salt. Neuroprotective (1987): serving to protect neurons from injury or degeneration. (MSNBC -- News)
Muscle Rubs: Use For Pain Is Questionable, Review Finds Jul 9, 2009
"But it is important to remember that not all analgesic gels or creams are the same, and for others there is very good evidence of effectiveness. Those will be dealt with in other reviews presently being finalised.". Adapted from materials provided by , via , a service of AAAS. Email or share this story. (Science Daily)
'No proof' that muscle rubs work Jul 8, 2009
They said other analgesic gels may well work, and recommended more research ... "But it is important to remember that not all analgesic gels or creams are the same, and for others there is very good evidence of effectiveness.". (BBC News -- Health)
Drug Curbs Severe Facial Pain Jul 7, 2009
Dr. Perez, of Hospital de La Princesa, Madrid and colleagues examined the effect of pregabalin in 65 patients with trigeminal neuralgia who had not received the agent before and had been resistant to previous analgesic therapy. Of this group, 36 received pregabalin alone and the remaining 29 used it in addition to their current therapy, mainly with non-steroidal anti-inflammatory drugs. (MEDLINEplus)
Cell transplantation and cardiac repair Jul 2, 2009
Among the limb-salvaged group, analgesic consumption was reduced by 62 percent and their total walking distance improved from zero to 40 meters. "This study found that after aBMC, in addition to being spared amputation, a critically ischemic leg can have increased blood flow and support wound healing while patients have reduced pain," concluded Dr. Amann. (EurekAlert!)
The trouble with Tylenol Jul 2, 2009
A: Yes, analgesics like acetaminophen and ibuprofen are the most frequently taken non-prescription drugs in the country, with between 16 percent and 20 percent of U.S. adults using them in a given week, according to a 2002 study in the Journal of the American Medical Association ... "There is no analgesic that provides pain relief without risk.". (MSNBC -- Health)
Demerol: Did It Cause Michael Jackson's Death? Jun 27, 2009
"His injuries, which he had sustained performing, where he had broken a vertebra and he had broken his leg from a fall on the stage, were getting in the way, Oxman said. I do not know the extent of the medications that he was taking. If he took other medications that are sedating which pain medications usually are in conjunction with Demerol, it can definitely cause shallow breathing and decreased oxygen levels, ultimately leading to respiratory arrest or heart attack, Anello said. What is... (Fox News)
Drug cocktail likely cause of Jackson's death: expert Jun 27, 2009
"I would love to know what doctor in his right mind would subscribe Demerol injections for somebody to be self-administered. "Demerol is a powerful analgesic. "It is used with great caution, even in a hospital setting by doctors because it is known to produce respiratory depression. "It is a drug for serious, severe pain. (Sydney Morning Herald -- World)
Stretching: The Truth Jun 26, 2009
He added, "I dont think it hurts you in general if you do it properly but it doesn't prevent injury." He's more supportive of stretching at other times, including after exercise, saying, "Regular stretching at other times is beneficial. It makes you stronger, jump higher, etc, and there are three studies suggesting it reduces injuries as well, although the results were only significant in one." He adds that "stretching is analgesic; it allows you to put your muscle through a wider range of... (CBS News -- Health)
Akela announces amendment to Fentanyl TAIFUN(R) license agreement with Teikoku Seiyaku Jun 17, 2009
Fentanyl is an opioid analgesic commonly used for the treatment of moderate to severe pain associated with conditions such as cancer ... About Teikoku Seiyaku Teikoku Seiyaku Co., Ltd. headquartered in Sanbonmatsu, Kagawa, Japan, is a world leader of manufacturing medicated patches and a pioneer in the field of anti-inflammatory and analgesic plasters. (Canada Newswire)
Discovery could ease cancer pain Jun 16, 2009
Analgesic drugs do not always work against cancer pain ... The biology of cancer pain is different to other types of pain, often rendering analgesic drugs ineffective. (BBC News -- Health)
Indian health care's victims Jun 16, 2009
truthful1 wrote on Jun 15, 2009 1:37 PM:" It tugs at my heart to read of any child's death, but more so when it is a First Nations child, because all too often these deaths were preventable. I, too, know first hand of the medical mayhem or lack of quality care and medicine at Indian Health run facilities and especially tribally managed facilities -the sad fact is that they are so underfunded that even if they had good doctors, these doctors would not be able to perscribe what is needed, nor... (Bismarck Tribune, ND)
Herbal Treatments for Psoriasis May 31, 2009
Analgesic and anti-inflammatory ... Analgesic, anti-inflammatory, and moisturizing. (Suite101.com)
Tailored Treatments Effective for Depression Due to Pain May 28, 2009
"It is possible that pain improvement in our trial reflected a main effect of improved mood [i.e., an antidepressant effect on mood rather than an analgesic effect], and that as depression lifts, patients may experience pain as being less intense and less disabling," wrote Dr. Kurt Kroenke, of the Indiana University School of Medicine and the Regenstrief Institute in Indianapolis, and colleagues. "Conversely, it is also possible that the improvement in depression was mediated by an improvement... (MEDLINEplus)
Echo Therapeutics Licenses Needle-Free Prelude SkinPrep System to Ferndale Pharma for Enhanced Delivery of Topical Lidocaine May 28, 2009
Ferndale will also be responsible for all product development and regulatory costs for the final development of the Prelude SkinPrep System for topical analgesic/anesthetic drug delivery applications ... Ferndale's LMX 4 topical analgesic cream uses advanced formulation know how that significantly enhances product performance ... LMX 4 is the leading brand in its class and is widely recognized for its fast onset of analgesic action, wide margin of safety and superior ease of use. (Canada Newswire)
PG Archive: Haddix Calm Under No-Hit Clamor May 24, 2009
"Before I put it on his chest," said Whelan, "I put analgesic balm on his chest to break up the congestion. I put some into his nostrils, too.". A newspaperman, wanting to raise the possibility of Harvey's pitching a second consecutive no-hitter, hedged by saying first. (Pittsburgh Post-Gazette, PA -- Sports)
Murder and morphine: Brutal killer high on the drug May 21, 2009
Ipoh OCPD Asst Comm Azisman Alias said the analgesic drug could have caused him to be extremely violent when he slashed and killed a mother, her five-year-old son and their maid on Wednesday. The 26-year-old suspect has been remanded until May 27, he said after accompanying Deputy Home Minister Datuk Wira Abu Seman Yusop to visit the remaining family members on Thursday. (The Star Online, Malaysia -- News)
The "Government Option": "Single Payer" By Another Name May 20, 2009
The boss may even include a slight pay hike with the notice as a nod to the enormous savings he or she will be achieving by off-loading the cost of employee health care, but that bump --if it comes at all-- will be a short term analgesic that will mask the onset of long-term pain. The "government option" will quickly become the single payer nightmare that is Canadian health care, and Americans will look back at the summer of 2009 and wonder when this became the American way of medicine. (Townhall.com)
Why I Give Pot to My 9-Year-Old May 13, 2009
Cannabis has long-documented effects as an analgesic and an anxiety modulator. Best of all, it is safe. (Slate)
Labopharm Reports Results for First Quarter Fiscal 2009 May 7, 2009
Once-Daily Tramadol Launched in the U.S. Labopharm's once-daily tramadol is now available in the U.S. Marketed and distributed in the U.S. by Purdue Pharma Products L.P. under the brand name Ryzolt(TM), the product is the first and only analgesic that contains both immediate and extended release components of tramadol. Ryzolt(TM) is now stocked and available in more than 27,000 retail pharmacies across the U.S. "We are pleased to announce a major milestone for Labopharm, the U.S. launch of... (Canada Newswire)
Radon Spa Therapy For Arthritis Apr 17, 2009
Common treatments include tumor necrosis factor inhibitors, corticosteroids and anti-inflammatory agents, analgesics, herbal medicine, immunomodulatory, physical therapy, surgery, rehabilitative treatment, orthopedic aids, and spa therapies, such as hydrotherapy and massage ... Evidence from empirical experience and from clinical observational studies suggests that radon has analgesic, anti-inflammatory, and immunomodulatory effects. (Suite101.com)
'Two-handed' Marine Microbes Point To New Method For Isolating Harmful Forms Of Chemicals Apr 17, 2009
In another commonly used chiral drug, naproxen, one isomer is analgesic; the other causes liver damage. In their paper, the researchers describe how they designed a microfluidic environment--a device about the size of an iPod nano that has channels containing water and bacteria--to create a "shear" flow of layers of water moving at different speeds. (Science Daily)
Shortage of pain-relief drug hits region Apr 13, 2009
Because of the shortage, Dr. Conermann said, his institute has been prescribing Percocet, an analgesic that combines oxycodone and the over-the-counter pain medication acetaminophen. "There are different options, but in most instances we have been able to replace oxycodone with Percocet with a moderate degree of success," Dr. Conermann said. (Pittsburgh Post-Gazette, PA)
'Pain in the ICU' report suggests comprehensive approach Apr 8, 2009
Analgesic TrialTo verify the presence of pain, the ICU team can administer a low dose of first-line analgesic followed by observation of the patient's pain-related behaviors. Surrogate ReportingIf patients are unable to communicate, the ICU team can use "surrogate reports" from family members who may be able assess a loved one's pain based on history. (EurekAlert!)
Post-Op Painkillers Tied to Deaths After Spinal Fusion Apr 7, 2009
Among this group, middle-aged men with degenerative disc disease (DDD) ran a sevenfold greater risk of either accidental or suicidal analgesic poisoning compared to the other surgical patients ... "Analgesic-related deaths are responsible for more deaths and more potential life lost among workers who underwent spinal fusion than any other cause," lead researcher Sham Maghout Juratli of Wayne State University School of Medicine in Detroit, said in a news release issued by the journal's publisher.... (MEDLINEplus)
Labopharm reports results for Phase III study on twice-daily tramadol-acetaminophen formulation Apr 2, 2009
The results of this study are however statistically significant under analyses that the Company believes may be accepted for the evaluation of analgesics in Europe, Canada and other jurisdictions ... About Tramadol-Acetaminophen Combination Products Tramadol-acetaminophen products leverage the unique but complementary modes of action of each of the active ingredients to provide the analgesic strength of a mild opioid (tramadol) and the rapid pain relief of acetaminophen. (Canada Newswire)
How Humor Makes You Friendlier, Sexier Mar 26, 2009
Amusement s ability to counteract physical agony is well documented, and as Cousins s experience suggests, humor s analgesic effect lasts after the smile has faded. Cheerfulness, a trait that makes people respond more readily to laugh lines, is linked to emotional resilience the ability to keep a level head in difficult circumstances and to close relationships, studies show. (Scientific American)
Restaurant proprietor charged in drug bust Mar 23, 2009
Oxycodone is an opium-derived analgesic medication prescribed for moderate to severe pain. OxyContin is the name brand of an extended-release form of oxycodone that was first marketed to cancer patients in 1996 by the company Purdue Pharma. (Juneau Empire)
Liking Sweets Makes Sense For Kids Mar 21, 2009
It's also known that sweet taste acts as an analgesic in children, reducing their perception of pain. Now researchers at the Monell Chemical. (Science Daily)
Prescriptions written for Anna Nicole Smith Mar 13, 2009
- hydromorphone, also known under the trade name Dilaudid, an opioid analgesic ... - Vicodin, a narcotic analgesic and cough suppressant. (Anchorage Daily News)
'Miraculous' Effects, Pain Relief Of Osteoplasty Shown For Those Suffering From Metastatic Bone Disease Mar 11, 2009
He noted that osteoplasty provided effective pain regression for individuals with both painful bone metastases and benign lytic lesions that didn't respond to conventional analgesic treatment. Bones are the third most common location where cancer cells spread and metastasize. (Science Daily)
Specter of addiction haunts Mar 11, 2009
Physicians readily prescribed OxyContin as an analgesic medication. Now, the addictive nature of OxyContin is known to the public, and physicians use more caution in prescribing this medicine to their patients. (NJ.com -- Times)
The Stupidest Plot Ever for Smuggling Cocaine Through Customs Mar 10, 2009
(Cocaine wouldn't be a good choice, thoughits analgesic effects are highly localized. . (Slate)
Hot Chili Peppers Help Unravel The Mechanism Of Pain Feb 24, 2009
"When stimulated it opens, letting outside calcium enter the cells until the receptor shuts down, a process called desensitization. The analgesic action of capsaicin is believed to involve this desensitization process. However, how the entry of calcium leads to the loss of sensitivity of the neurons was not clear.". Capsaicin creams are commonly sold over the counter as effective treatment for a variety of pain syndromes, from minor muscle or joint aches to those that are very difficult to... (Science Daily)
New Method To Eliminate Ibuprofen From Polluted Waters Using Ultrasound Feb 24, 2009
The substance chosen for the study was ibuprofen, as it is one of the drugs that appears with the most frequency in the analyses of waste waters due to its high consumption as an anti-inflammatory and analgesic. "Pharmaceutical compounds are pollutant substances from the moment in which they maintain their pharmacological activity outside the environment for which they were designed", Fabiola M;ndez-Arriaga explains to SINC. She is the co-author of the study and a researcher at the Department of... (Science Daily)
Savient Provides Update on Pegloticase BLA Feb 13, 2009
Since its formation on November 19, 2008, the Committee, Chaired by Board Member Dr. Lee S. Simon, M.D., a former Director of the Analgesic, Anti-Inflammatory, Ophthalmologic Drug Products Division of the FDA and a Board Certified Rheumatologist with 25 years of clinical practice experience, has assumed oversight of all Company activities related to the FDA's BLA review process. The Committee has conducted a comprehensive review of the BLA filing with the assistance of external experts. (PR Newswire)
Nature Reviews Drug Discovery Feb 8, 2009
With the aim of highlighting approaches to tackling the challenges in this field, this special collection integrates articles that discuss strategies to drive forward analgesic drug development with those that explore new targets for pain therapeutics. Produced with support from Eli Lilly and Company, which had no control over its content. (Nature News Service)
Zen Meditation Alleviates Pain, Study Finds Feb 7, 2009
Pain Sensitivity and Analgesic Effects of Mindful States in Zen Meditators: A Cross-Sectional Study. Psychosom Med, 2009 71: 106-114. (Science Daily)
Pain Pills in Heart Failure Patients May Be Risky Feb 7, 2009
"Further research is required to establish the cardiovascular risk associated with all NSAIDs in subgroups of patients with cardiovascular disease, particularly if a low dosage with analgesic effect can be used without increased risk," Gislason and colleagues note. "In the meantime, because of the accumulating evidence," they conclude, "general awareness is required among physicians, health care authorities, and the general public about the potential cardiovascular risk of NSAIDs, in particular... (MEDLINEplus)
Depression, Age Linked to Post-Prostatectomy Pain Feb 7, 2009
These results imply that "pain once manifested is not easily converted despite a generous analgesic treatment," Swedish investigators explain in the current issue of BMC Nursing. "This may be more evident in ... younger and depressive patients, who might benefit from a more aggressive therapy instituted in the very early postoperative period.". (MEDLINEplus)
Pain Program Reduces Bone Surgery Pain in Elderly Feb 7, 2009
NEW YORK (Reuters Health) - Among older adults who have undergone orthopedic surgery, an interdisciplinary analgesic program can improve postoperative pain, reduce chronic pain, and improve function, according to Dr. R. Sean Morrison, of Mount Sinai School of Medicine, New York, and colleagues ... Elderly adults who undergo orthopedic surgery of the hip or knee experience intense postoperative pain and may receive suboptimal analgesic therapy ... "At 6 months, intervention patients were less... (MEDLINEplus)
