Computers Reveal Unexpected Drug Side Effects Nov 7, 2009
29, 2008) Around 150 thousand people per year get the parasitic disease African sleeping sickness, but the only medicines to treat it are either difficult to administer, expensive, or toxic. Now a team of. (Science Daily)
African Cattle To Be Protected From Killer Disease Oct 6, 2009
5, 2009) Millions of African families could be saved from destitution thanks to a much-needed vaccine that is being mass-produced in a drive to protect cattle against a deadly parasite. East Coast fever is a tick-transmitted disease that kills one cow every 30 seconds with one million a year dying of the disease. (Science Daily)
Aiming at genetic cure to disease Aug 20, 2009
Current NanoAxis research projects include using gene therapy for African sleeping sickness, treating seasonal and pandemic influenza such as swine flu, treating Alzheimer s Disease and devising a test kit for cancer and other diseases using quantum dot technology. We hope to take the lead in the area of infectious disease research and believe that use of quantum dots may replace conventional targeting methods such as adenoviral vectors and provide a truly novel form of gene therapy,... (Buffalo Business First, NY)
New Consortium to Develop Drugs for Neglected Tropical Diseases Aug 17, 2009
LEIDEN, The Netherlands, August 17 /PRNewswire/ -- A new consortium has been formed to boost drug development for the treatment of two deadly diseases, African sleeping sickness and Leishmaniasis, which affect millions of people worldwide ... Rob Leurs (VU University Amsterdam), the project's principal investigator, comments: "African sleeping sickness and Leishmaniasis are diseases caused by parasites. Both diseases are prominent on the World Health Organization's list of neglected tropical... (PR Newswire)
Core Nuclear Pore Elements Likely Shared By All Eukaryotes Jul 14, 2009
Published June 13 in Molecular & Cellular Proteomics, research performed by former graduate student Jeffrey A. DeGrasse, now at the United States Food and Drug Administration, picked apart the proteins that make up the nuclear pore complex of Trypanosoma brucei, a deadly, single-celled parasite responsible for African sleeping sickness. In the evolutionary tree of eukaryotic life, T. brucei is about as far removed from vertebrates like ourselves as possible, far more distant than commonly used... (Science Daily)
New Insight On Therapy For Devastating Parasitic Disease Jul 3, 2009
28, 2008) Scientists have identified a long-sought chink in the armor of the parasite that causes African sleeping sickness, a parasitic disease that kills at least 50,000 people each. (Apr. (Science Daily)
Chemists Develop Distributed Drug Discovery: Finding Drugs For Neglected Diseases Jun 19, 2009
26, 2007) The neglected tropical diseases are a group of 13 infectious diseases, including elephantiasis, hookworm, African sleeping sickness and trachoma, which affect more than one billion people worldwide ... 16, 2005) Only about 1% of newly developed drugs are for tropical diseases, such as African sleeping sickness and dengue fever. (Science Daily)
Knowledge Of Epigenetics Helps Scientists Develop Tool To Study Deadly Parasite’s Histone Code May 25, 2009
In a genome-wide study led by George A.M. Cross, head of the Laboratory of Molecular Parasitology, and T. Nicolai Siegel, a graduate student in the lab, scientists at Rockefeller University have mapped epigenetic changes that are likely to play a role in initiating the transcription of genes in Trypanosoma brucei, the deadly single-celled parasite responsible for African sleeping sickness. The advance marks the first time scientists have been able to develop the tools to map these changes across... (Science Daily)
Genital Stimulation Opens Door For Cryptic Female Choice In Tsetse Flies May 22, 2009
28, 2008) Scientists have identified a long-sought chink in the armor of the parasite that causes African sleeping sickness, a parasitic disease that kills at least 50,000 people each. (July 30, 2008) More than 80 new proteins, thought to play a role in reproductive success, have been discovered in the seminal fluid of fruit. (Science Daily)
Parasite Breaks Its Own DNA To Avoid Detection Apr 20, 2009
19, 2009) The parasite Trypanosoma brucei, which causes African sleeping sickness, is like a thief donning a disguise ... 28, 2008) Scientists have identified a long-sought chink in the armor of the parasite that causes African sleeping sickness, a parasitic disease that kills at least 50,000 people each ... 6, 2006) Researchers have made a crucial breakthrough in the journey towards finding a treatment for African Sleeping Sickness. (Science Daily)