Treatment of Anemia in Chronic Kidney Disease — Strategies Based on Evidence Nov 19, 2009
Anemia associated with chronic kidney disease and end-stage renal disease is due, in large part, to reduced production of renal erythropoietin and abnormalities in extracellular-fluid volume homeostasis. 1 Moreover, anemia and disordered salt and water handling, which usually manifest as hypertension, predict cardiovascular and renal outcomes in patients with chronic kidney disease. (New England Journal of Medicine)
A Man with Cough, Hoarseness, and Abnormalities on Chest Imaging Nov 19, 2009
NEJM -- Case 36-2009 -- A 23-Year-Old Man with Cough, Hoarseness, and Abnormalities on Chest Imaging ... Case 36-2009 A 23-Year-Old Man with Cough, Hoarseness, and Abnormalities on Chest Imaging ... Dr. David T. Ting (Medical Oncology): A 23-year-old man was transferred to this hospital because of cough, hoarseness, fever, and abnormalities on chest imaging. (New England Journal of Medicine)
ASK DR. H: Many causes of miscarriage Nov 19, 2009
About 7 percent of all miscarriages or stillborn deaths are due to a chromosomal abnormality. There may be a disease or infection that the mother has contributing to an unfavorable environment for a developing baby to grow and develop. (Atlanta Journal-Constitution -- Health)
Blindness Causes Structural Brain Changes, Implying Brain Can Re-Organize Itself to Adapt Nov 19, 2009
5, 2008) 3T MRI is better at detecting and characterizing structural brain abnormalities in patients with focal epilepsy than 1. 5T MRI, leading to a better diagnosis and safer treatment of patients, according. (Science Daily)
Monetary Gain and High-Risk Tactics Stimulate Activity in the Brain Nov 18, 2009
18, 2009) Researchers trying to uncover the mechanisms that cause attention deficit hyperactivity disorder and conduct disorder have found an abnormality in the brains of adolescent boys suffering from the. (Nov. (Science Daily)
New Combination Therapy Could Deliver Powerful Punch to Breast Cancer Nov 18, 2009
31, 2004) Because up to 75 percent of breast cancer patients have an abnormality in a specific cell signaling pathway, drugs that target different molecules along that pathway may be especially effective for. (Oct. (Science Daily)
First Clear Idea Of How Rare Bone Disease Progresses Nov 18, 2009
17, 2009) An international team of scientists, led by researchers at the University of Pennsylvania School of Medicine, is taking the first step in developing a treatment for a rare genetic disorder called fibrodysplasia ossificans progressiva (FOP), in which the body's skeletal muscles and soft connective tissue turns to bone, immobilizing patients over a lifetime with a second skeleton. Reporting in the November issue of the Journal of Clinical Investigation senior authors Eileen Shore, PhD,... (Science Daily)
Why Having Breast Cancer Screenings Too Early Can Be Bad for You Nov 18, 2009
What these tests have in common is that they look for early warning signs, including small cellular abnormalities, in healthy, asymptomatic peoplesometimes as part of a checkup, sometimes as part of a public-outreach program ... Not only do some abnormalities grow very slowly, some actually regress without treatment, as a result of complex interaction between precancerous cells and the body's immune system. (Slate)
Dr. Jeff Hersh: Be aware of lung cancer risks Nov 18, 2009
CT scans may reveal abnormalities that are not cancer (30 percent to 60 percent of smokers will have some abnormality noted), but that trigger extensive (and often invasive) evaluations, which carry their own morbidity and mortality. Furthermore, there is at least a theoretical concern that the radiation from the CT scan(s) could induce cancer. (Belmont Citizen Herald, MA)
Plastic chemicals 'feminise boys' Nov 17, 2009
The same researchers have already shown that this can mean boys are born with genital abnormalities. Now they say certain phthalates also impact on the developing brain, by knocking out the action of the male hormone testosterone. (BBC News -- Health)
Mammograms Should Start for Women at Age 50, Not 40, U.S. Panel Recommends Nov 17, 2009
A false positive, in which an abnormality is seen that proves not to be cancer, typically leads to additional screenings and tissue biopsies, the panels researchers said. Computer Modeling. (Bloomberg -- US)
Young athletes need dual screening tests for heart defects, study suggests Nov 16, 2009
Using just 1 popular test or the other could miss serious cardiac abnormalities ... The researchers were looking for life-threatening cardiac abnormalities, such as hypertrophic cardiomyopathies ... Twenty-two of those abnormalities were found by EKG alone, nine by ECHO alone and five were picked up on both tests. (EurekAlert!)
Pilot study relates phthalate exposure to less-masculine play by boys Nov 16, 2009
Phthalates are becoming more controversial as scientific research increasingly associates them with genital defects, metabolic abnormalities, and reduced testosterone in babies and adults. A federal law passed in 2008 banned six phthalates from use in toys such as teethers, play bath items, soft books, dolls and plastic figures. (EurekAlert!)
* War brings a surge of birth defects in Fallujahs children Nov 15, 2009
Doctors and parents tell of huge growth in abnormalities in children of a city that saw some of the fiercest fighting X and largest quantities of munitions X of the conflict in Iraq ... Now, every day in my clinic or elsewhere in the hospital, there are large numbers of congenital abnormalities or cases of chronic tumors ... The numbers of abnormalities we are seeing is horrific and no one has yet concluded why, said Allah. (Taipei Times, Taiwan -- World)
Beef Producers’ Questions Answered By Breed Association Representatives (2) Nov 15, 2009
Genetic abnormalities. On the topic of genetic abnormalities, an audience member asked how each breed association is working to battle these problems ... These animals are still able to be registered so that the abnormalities can be found and tracked. (Agri-View, WI)
6-year-old has endured open-heart surgeries, yet remains a happy little girl Nov 15, 2009
About 90 percent of children born with heart defects today are expected to survive to adulthood, in large part because of medical advancements in open-heart surgeries that correct many abnormalities. There is nothing parents of a congenital heart disease baby could have done to prevent defects. (Florida Today)
* The effects of war on health Nov 15, 2009
No studies have been done, among either combatants or civilians, so it is impossible to link it to the abnormalities. These birth defects in Fallujah could be the result of multiple factors including the sheer psychological stress on the local population of being in a war zone, malnutrition, air and water pollution and a cocktail of chemicals, which may include contamination from munitions, said Brown. (Taipei Times, Taiwan -- World)
Faulty Body Clock May Make Kids Bipolar Nov 14, 2009
Its expression is known to change as a function of circadian rhythm in some tissues, and mice without the gene exhibit circadian rhythm abnormalities. According to Niculescu, "Bipolar disorder is often characterized by circadian rhythm abnormalities, and this is particularly true among pediatric bipolar patients. Decreased sleep has even been noted as one of the earliest symptoms discriminating children with bipolar disorder from those with attention deficit hyperactivity disorder (ADHD). It... (Science Daily)
Less HRT, Fewer Cases of Possible Breast Cancer Precursor Nov 14, 2009
This occurred despite an increase over time of rates of mammography, which tend to pick up the abnormality. Meanwhile, breast cancer cases in women with atypical ductal hyperplasia declined from 4. (MEDLINEplus)
Researchers 'Notch' A Victory Toward New Kind Of Cancer Drug Nov 13, 2009
Similar abnormalities in NOTCH also underlie a variety of other cancers, including lung, ovarian, pancreatic and gastrointestinal cancers. Even with this deep scientific knowledge, drugs against NOTCH -- or any other transcription factor -- have traditionally been extremely difficult, if not impossible, to develop. (Science Daily)
SPECIAL REPORT: Welcome to the Clone Farm Nov 13, 2009
Some animals are born with abnormalities and have to be euthanized and some have more health problems at birth than conventionally bred animals. Large Offspring Syndrome also occurs more often with assisted breeding technologies like cloning. (The Star Online, Malaysia)
Artificial Penis Tissue Proves Promising in Lab Tests Nov 13, 2009
The real hope is "that patients with congenital abnormalities, penile cancer, traumatic injury and some cases of erectile dysfunction will benefit from this technology in the future," Atala said. FOX NEWS VIDEOS. (Fox News)
> Best in Business II: Retina Institute of Hawaii Nov 13, 2009
Approximately 40 percent of them were found to have abnormalities in at least one eye, further highlighting the need for early detection. Pages: 1. (Pacific Business News, HI)
Scientists inch closer to kids from 3 parents Nov 13, 2009
IVF often fails in older women and one reason is thought to be abnormalities in the cytoplasm of their eggs. If we could transfer these constructed new embryos, I believe the success rate would be high, said Tanaka, the lead researcher of the study. (India Times, India)
Klay: no physical proof Nov 13, 2009
She testified Klay had no abnormalities, apart from a "mildly decreased anal tone" and a haemorrhoid. Her findings could not be specifically attributed to the penetration that allegedly occurred, she said. (iAfrica.com)
Coming soon: 'Three-parent' babies... Nov 13, 2009
IVF often fails in older women because there are abnormalities in the outside of their eggs, known as cytoplasm, which surrounds the nucleus. The team at St Mother Hospital in Kitakyushu, Japan, believe one way around the problem would be too implant the healthy nucleus - which contains most of the information to produce a baby - into the cytoplasm of a donor, usually a younger mother. (The Drudge Report)
Mechanical ventilation for patients with lung damage don't always work as planned Nov 13, 2009
By explaining why a patient has a physiological abnormality such as a decrease in oxygenation or worsening kidney function, these measurements can suggest therapies to correct the abnormal physiology. Many physiological interventions can be quickly instituted and monitored at the bedside. (EurekAlert!)
Enke death: Roots of depression Nov 13, 2009
Scientists are discovering a different kind of answer which has to do with the types of abnormalities in the brain and body that are characteristic of people with depression. We might say that depression is caused by hyperactivity of body-brain danger pathways and not enough activity in brain areas that help us get a grip on our emotions. (CNN)
Cancer protein 'can be disarmed' Nov 12, 2009
Similar abnormalities in Notch also underlie other cancers, including lung, ovarian, pancreatic and gastrointestinal tumours. Examining the structure of Notch closely, the researchers isolated a potential weak spot in its structure. (BBC News -- Health)
1 out of 4 breast cancers not life threatening Nov 12, 2009
The research has further heated up the question: what part of abnormalities picked up by the mammogram tests can actually threaten life. Epidemiologist Dr Stephen Morrell of the University of Sydney and her colleagues studied cases in New South Wales and found that the number of women diagnosed with breast cancer and aged between 50-69 increased almost two times after tests began. (India Times, India)
State Won't Seek Death in Shovel Murder Case Nov 11, 2009
"There were no gross abnormalities on his head. It was just 'he was hit with a shovel, so that must be what killed him.' There is no evidence of premeditation or malice in this case. I propose $25,000 secured, with house arrest.". Webb wanted to know if Castillo had the means to obtain such a bond. (The Pilot Newspaper)
Laboratory-Grown Replacement Of Penile Erectile Tissue In Animals Suggests Potential To Benefit Patients Nov 11, 2009
"Our hope is that patients with congenital abnormalities, penile cancer, traumatic injury and some cases of erectile dysfunction will benefit from this technology in the future.". Reconstructing damaged or diseased penile erectile tissue has traditionally been a challenge because of the tissue's unique structure and complex function. (Science Daily)
Rabbits given lab-grown penises Nov 11, 2009
He said patients with congenital abnormalities, penile cancer, traumatic injury and some cases of erectile dysfunction could benefit most from the technology. But Associate Professor David Leavesley, a cell biologist and tissue engineer from the Queensland University of Technology, said that could still be decades off. (Sydney Morning Herald -- Australia)
Olympus introduces world's smallest GI scope to offer 4-way angulation and Narrow Band Imaging Nov 11, 2009
November 10, 2009 Olympus today introduced the world's smallest gastrointestinal videoscope to offer four-way angulation and Narrow Band Imaging (NBI) to detect upper gastrointestinal abnormalities ... Olympus introduces the world's smallest gastrointestinal videoscope to offer four-way angulation and Narrow Band ImagingT (NBI) to detect upper gastrointestinal abnormalities. (EurekAlert! -- Business News)
Scientists Grow New Penile Tissue in the Lab Nov 11, 2009
"Our hope is to be able to treat patients with many conditions, including congenital abnormalities of the penis, traumatic injuries, penile cancer and severe cases of erectile dysfunction that don't benefit from drug treatments." ... In clinical trials, about 30 children and adults with congenital bladder abnormalities or bladder injuries who were treated with the engineered tissue showed normal or improved bladder function for nearly 10 years, Atala said. (MEDLINEplus)
Allon Therapeutics Releases Third Quarter Operating Results Nov 11, 2009
PSP is a degenerative brain disease that is often characterized by progressive difficulty with balance and walking, eye movement abnormalities, and cognitive and personality changes. The pathology of Alzheimer's disease and many forms of FTD has some similarities, including the presence of impaired forms of the brain protein tau. (CCNMatthews Press Releases)
Anesthesia, Exertional Heat Deaths May Be Linked Nov 11, 2009
They collapsed during intense exercise or military training, and subsequent tests showed they had the gene abnormality that causes malignant hyperthermia. The cases offer clues about a possible relationship between exertional heat illness and malignant hyperthermia, but the doctors said that further study is needed to clarify the link. (MEDLINEplus)
Botox Takes A Shot At Pain Nov 10, 2009
31, 2006) Researchers at Massachusetts General Hospital have found the first evidence of a physical abnormality underlying the chronic pain condition called reflex sympathetic dystrophy or complex regional. . (Science Daily)
Plane's engine tested day before deadly crash Nov 10, 2009
com An engine test the day before an airplane crash in an Eastside neighborhood that killed two Florida men showed no abnormalities with the 52-year-old Japanese Fuji LM-1 craft, the National Transportation Safety Board said. No abnormalities seen during maintenance ... An engine test the day before an airplane crash in an Eastside neighborhood that killed two Florida men showed no abnormalities with the 52-year-old Japanese Fuji LM-1 craft, the National Transportation Safety Board said. (Athens Banner-Herald)
Penis tissue replaced in the lab Nov 10, 2009
Professor Anthony Atala said: "Further studies are required, of course, but our results are encouraging and suggest that the technology has considerable potential for patients who need penile reconstruction. "Our hope is that patients with congenital abnormalities, penile cancer, traumatic injury and some cases of erectile dysfunction will benefit from this technology in the future. " Reconstructing damaged or diseased penile erectile tissue is a tough challenge because of the tissue's complex... (BBC News -- Health)
Yoga improves heart health Nov 10, 2009
In healthy individuals HRV is high whereas cardiac abnormalities lead to a low HRV.. To reach the conclusion, Ramesh Kumar Sunkaria, Vinod Kumar, and Suresh Chandra Saxena of the Electrical Engineering Department, at the Indian Institute of Technology in Roorkee, have evaluated two small groups of men in order to see whether yoga practitioners can improve heart health. (India Times, India)
Developmental delay could stem from nicotinic receptor deletion Nov 9, 2009
8, 2009) The loss of a gene through deletion of genetic material on chromosome 15 is associated with significant abnormalities in learning and behavior, said a consortium of researchers led by Baylor College of Medicine () in a report that appears online today in the journal Nature Genetics. "This research goes about 95 percent of the way to pinning these problems in a specific group of individuals to this gene," said Dr. Arthur L. Beaudet (), chair of molecular and human genetics at BCM. He... (EurekAlert!)
Frontiers of the future: In-gene-ous modifications Nov 7, 2009
On the one hand, human genes are studied to locate abnormalities, which cause disorders or make an individual more susceptible to various diseases. Switching that gene off can affect the onset of the disease. (India Times, India -- Health/Science)
Ski accident Nov 7, 2009
" When he was well enough to leave hospital Chas went to the Children's Trust - a national charity working with children who have multiple disabilities. He spent four months with the charity at its base in Tadworth, Surrey, learning the nuances of daily living. "At the Children's Trust, he was learning more of the subtleties of existing every day - how to plan a trip to the shower and how to speak to people," his mother said. HAEMATOMA Haematoma comes from the Greek words "haema", meaning blood,... (BBC News -- UK)
It's So Hard To Say I'm Sorry Nov 7, 2009
I think Dr. Parikh didn't see the abnormality in the boy's eye because he wasn't looking for it; had he been searching for any and all clues as to cause of the problem, he might have looked at everything more closely. It's the same reason why you've never noticed a particular store that you've driven by a million times until someone points it out to you--it just wasn't relevant information at the time. (Slate)
Somerset man designated predator Nov 7, 2009
President Judge John M. Cascio made his decision about Adam Joseph Carnline, 24, after a representative of the Pennsylvania Sexual Offenders Assessment Board testified (Somerset Daily American, PA)
Meadville hospital begins construction of new breast imaging center Nov 6, 2009
"Another advantage is that you can see through breast tissue better than you can with traditional film-mammography units." The new units will be particularly helpful for younger women, who often have denser breast tissue that makes it more difficult to see tiny abnormalities on a mammogram. Digital mammograms also take less time than film mammograms, expose the patient to less radiation and reduce the time a patient's breast is compressed. (Erie Times-News, PA)
Researcher: 'Optical biopsy' for breast cancer increasingly accurate Nov 6, 2009
Most biopsies following mammograms reveal benign abnormalities, not cancer ... But at least three out of four biopsies following mammograms conclude that observed abnormalities are benign and that no intervention was needed, Jiang said ... His main conclusion: His technique correctly identified biopsy confirmed malignancies nearly 75 percent of the time, with the most accurate results from older patients, whose softer breasts make abnormalities more prominent. (EurekAlert!)
Sex & amnesia ... not a soap opera Nov 6, 2009
Studies that took advanced brain imaging of patients experiencing TGA showed abnormalities in the cerebral arteries in the left hippocampus of some, Caplan said. "It's not enough of a stimulus or deprivation that it permanently injures the brain. The brain recovers," he said. (CNN)
DC Sniper's Attorney Speaks Only To 9NEWS NOW Nov 6, 2009
He says, "These abnormalities are important because it tells us we know Mr. Muhammad is not functioning in a normal way.I have determined Mr. Muhammad has several malformations in his brain.". The recordings also incudes an interview with Elizabeth Young, a juror in the case who's had a change of heart. (W-USA News, DC)
New technology aids in breast cancer detection Nov 5, 2009
According to Steve Danehy, director of media relations, communications and marketing at Lahey, the Burlington hospital is the only hospital to utilize the new technology, which involves injecting a radioactive dye into the breast and using a specialized high-resolution camera to illuminate any abnormalities that could be cancerous ... We are able to look at that image much bigger than life and that allows us to zoom in literally on abnormalities and get a closer look at areas we are concerned... (Lincoln Journal, MA)
Students share hope, help for breaking the cycle of self-destructive behavior Nov 5, 2009
Fatal abnormalities in heart rhythm can occur, the stomach can perforate from binging, and vomiting can cause tears in the esophagus, gastrointestinal bleeding, and ulcers. The more serious health risks take longer to be detected or to become worrisome enough for the people with eating disorders to seek help. (Lake City Reporter, FL)
Myelodysplastic Syndromes Nov 5, 2009
Volume 361:1872-1885. Ayalew Tefferi, M.D., and James W. Vardiman, M.D.. (New England Journal of Medicine)
The Time Traveler's Wife Nov 5, 2009
Niffenegger is vague about the cause, airily writing it off as a chromosomal abnormality, but she's precise about its effects. It's as if Henry is at the mercy of some not-so-benign higher power addicted to the remote control button. (Sydney Morning Herald -- Entertainment)
Effectiveness of cancer screenings questioned Nov 4, 2009
"In prostate and breast cancer screening, we do find things, sometimes very serious cancers," she said, adding that tests also detect abnormalities that may not be cancer. "I look at this as a form of success, that one has this problem. ... We're now at a time where we have to use the power of biology ... to try and sort out which is which, which are the bad ones, which will respond to therapies.". (Pittsburgh Post-Gazette, PA)
Notorious 'Man-eating' Lions Of Tsavo Likely Ate About 35 People -- Not 135, Scientists Say Nov 4, 2009
(June 10, 2008) An increase of epileptic seizures and behavioral abnormalities in California sea lions can result from low-dose exposure to domoic acid from toxic algal blooms as a fetus. This brain disturbance is a. (Science Daily)
Some Antibiotics May Increase Birth Defects Nov 4, 2009
For example, she noted, a severe heart abnormality known as hypoplastic left heart syndrome, which was three times as common among women who took sulfonamides and four times more frequent among those who used nitrofurantoins, occurs in one in every 42,000 births. If risk is tripled, Crider pointed out, that still means only one case in every 14,000 births. (Newsmax)
Clinical Tests Begin On Medication To Correct Fragile X Defect Nov 4, 2009
There has to date been no medication that could alter the disorder's neurologic abnormalities. The study will evaluate safety, tolerability, and optimal dosage in healthy volunteers. (Science Daily)
Terrible Teens Of T. Rex: Young Tyrannosaurs Did Serious Battle Against Each Other Nov 3, 2009
It also confirmed that there were no other abnormalities in the bone adjacent to the lesions. " Because the dinosaur had not reached maturity, the researchers concluded that the combat was not likely over sexual conflict or competition but might have been a learning behavior for young dinosaurs prompted by a show of dominance or territorial dispute. Peterson says other adolescent animals, particularly juvenile crocodiles, exhibit such fighting behavior. "It's common to find similar puncture... (Science Daily)
Mount Sinai assessing health impacts of 1 of the nation's largest environmental disasters Nov 3, 2009
The third investigation will examine the relationships between autoimmune disorders, autoimmune antibody abnormalities, and CT-scan evidence of scarring lung disease in the context of exposure to Libby asbestos. Auto-immune disorders such as rheumatoid arthritis and lupus have been found to occur more frequently in Libby, and antibody levels to the body's own tissues are found in Libby residents more frequently and at higher concentrations. (EurekAlert!)
Innovative Imaging System To Study Sudden Cardiac Arrest Developed Nov 2, 2009
11, 2009) Researchers conducting a large, ongoing study to improve detection and prevention of sudden cardiac death were surprised to discover that a specific heart rhythm abnormality -- idiopathic QT interval. (Oct. (Science Daily)
2 Mumbai doctors get jail for sex tests Nov 2, 2009
The centre can only run diagnostic tests by a qualified genetic counsellor to verify the family history to rule out certain genetic abnormalities. In this case, the magistrate said, ``with no qualifications to run a genetic counselling centre, both accused were doing so at Dr Adkar's nursing home and that amounted to ``false impersonation to the innocent public. (India Times, India)
Dr. Gott: Vegetarian diet endorsed by patient's doctor Nov 2, 2009
Because you have regular checkups and blood work, any abnormalities would be apparent, and your doctor would address them. Does your diet include beans, soy or other forms of protein. (Erie Times-News, PA)
Let juries determine sex offenders’ fate Nov 1, 2009
In Massachusetts, convicted sex offenders who complete their sentences get to choose whether a judge or jury will determine if they suffer from a mental abnormality that makes them a likely risk to reoffend. Such a finding results in confinement and, equally important, treatment in Bridgewater State Hospital. (Boston Globe)
Lighter sentence for murderer with 'bad genes' Oct 31, 2009
For the new report, Pietro Pietrini, a molecular neuroscientist at Italy s University of Pisa, and Giuseppe Sartori, a cognitive neuroscientist at the University of Padova, conducted a series of tests and found abnormalities in brain-imaging scans and in five genes that have been linked to violent behaviour including the gene encoding the neurotransmitter-metabolizing enzyme monoamine oxidase A (MAOA). A 2002 study led by Terrie Moffitt, a geneticist at the Institute of Psychiatry, King s... (Scientific American)
