Seizure Threats Linked to State Drug-Swap Laws May Trim Teva, Mylan Sales Feb 11, 2009
Sam, 17, went seven weeks without an episode while taking Zonegran, made by Tokyo-based After pharmacists switched him to generic copies made by four different companies, he suffered multiple seizures daily and was hospitalized three times before doctors identified differences between the medications as the cause, said Miller, of Dayville, Connecticut ... Products such as Zonegran and Johnson & Johnsons Topamax, also for epilepsy, may gain sales if the bans pass. (Bloomberg -- Japan)
FDA Adds Suicide Warning to Epilepsy Drugs Feb 7, 2009
In addition to clonazepam, phenytoin and topiramate, the drugs covered by the new FDA-mandated labeling are: carbamazepine (marketed as Carbatrol, Equetro, Tegretol, Tegretol XR); clorazepate (Tranxene); divalproex sodium (Depakote, Depakote ER, Depakene); ethosuximide (Zarontin); ethotoin (Peganone); felbamate (Felbatol); gabapentin (Neurontin); lamotrigine (Lamictal); lacosamide (Vimpat); levetiracetam (Keppra); mephenytoin (Mesantoin); methosuximide (Celontin); oxcarbazepine (Trileptal);... (MEDLINEplus)
FDA Warns Epilepsy Drugs May Raise Suicide Risk Feb 2, 2008
The drugs included in the warning are: Carbamazepine (marketed as Carbatrol, Equetro, Tegretol, Tegretol XR), Felbamate (marketed as Felbatol), Gabapentin (marketed as Neurontin), Lamotrigine (marketed as Lamictal), Levetiracetam (marketed as Keppra), Oxcarbazepine (marketed as Trileptal), Pregabalin (marketed as Lyrica), Tiagabine (marketed as Gabitril), Topiramate (marketed as Topamax), Valproate (marketed as Depakote, Depakote ER, Depakene, Depacon) and Zonisamide (marketed as Zonegran). Some... (MEDLINEplus)
Judge sends freeway crash case back to grand jury Nov 17, 2007
Judge Jeanne Garcia said prosecutors failed to tell the grand jury that Haluk Kandas, 31, a Turkish immigrant who lives in Ahwatukee, was taking Zonegran ... Sandweg said the ruling requires the County Attorney's Office to tell a second grand jury not only about Kandas' epilepsy, but also that Kandas was being treated by a neurologist, was medically cleared to drive, and routinely filled his prescription for Zonegran ... In a recent hearing, prosecutor Louis Stoltz told Garcia that Kandas told... (AZCentral -- News)
Crash charges may get 2nd look Oct 16, 2007
Dr. Barry Hendin, Kandas' Phoenix neurologist, prescribed Zonegran, an anti-seizure medicine. Kandas filled the $138 prescription each month, and was taking the medicine on the day of the crash, according to court records. (AZCentral -- News)
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Epilepsy Patients Fight Move To Generic Drugs Mar 16, 2007
" A pharmacist can legally substitute a generic drug for a medically necessary brand, provided the patient's doctor grants permission. But in practice, doctors say, it's common for pharmacists to make substitutions without the required approval. That's dangerous for epilepsy patients, whose medication is highly precise and who may not realize that a lower-cost option could be dangerous, said Karen Egozi, executive director of the Epilepsy Foundation of Florida. Egozi and several epilepsy... (Tampa Bay Online, FL -- News)
Antiepilepsy Drug Treats Binge-Eating Disorder Jan 24, 2007
NEW YORK (Reuters Health) - The anti-seizure drug zonisamide, which goes by the brand name Zonegran, is effective short-term treatment for binge-eating disorder associated with obesity, according to the results of a small study. However, the treatment is not well tolerated. (MEDLINEplus)
