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    News and Articles on Warfarin

    Archives: Warfarin

    Drug tests could save billions  Jan 5, 2009
    These include colorectal cancer, the use of the anti-coagulant Warfarin to prevent stroke, cholesterol-lowering drugs and anti-depression drugs. A spokesman for the Acting Health Minister, Justine Elliot, said a review of health technology assessment announced by the Government last month would explore the issue. (Sydney Morning Herald -- Australia)

    Optimal Warfarin Dosing Improves Anticoagulation Control  Jan 1, 2009
    TUESDAY, Dec. 30 (HealthDay News) -- While the anticoagulant warfarin can be highly effective in preventing strokes and treating venous thromboembolism, doctors have long struggled with finding the best way manage the drug therapy ... The research team analyzed warfarin use in almost 4,000 patients to determine what are the most effective levels of the drug in a patient's system under different circumstances ... "The study suggests that anticoagulation control could be improved considerably by... (MEDLINEplus)

    Guide on Blood Thinner Now Available in Spanish  Dec 31, 2008
    Brochure may help spread the word about warfarin's possible complications ... MONDAY, Dec. 29 (HealthDay News) -- A new pamphlet has been published to help Spanish-speaking patients understand what to expect and watch for while taking the blood thinner warfarin ... Millions of Americans take warfarin, available under the brand name Coumadin, because they have an irregular heartbeat (known as atrial fibrillation), they've had a heart attack, or they are trying to prevent or treat blood clots in... (MEDLINEplus)

    Genetic tests offer promise of personalized medicine  Dec 30, 2008
    And a genetic test might help doctors determine the optimal dose of warfarin, a blood thinner used by millions of Americans ... "If you save one hospitalization for every 100 new warfarin users, you more than offset the cost of testing all 100," said Dr. Robert Epstein, the chief medical officer of Medco Health Solutions, which manages prescription plans for employers. (International Herald Tribune)

    Older Adults Have More Drug Interactions  Dec 30, 2008
    " Ninety-nine percent, 2,976 respondents, completed the interview and medication log. Ninety-one percent of all respondents regularly used at least one medication, a percentage that increased with age. Twenty-nine percent of older adults took more than five prescription medications. Sixty-eight percent of the adults who took prescription drugs also used over-the-counter medications or dietary supplements. Men were more likely to take over-the-counter medicines. Women were more likely to use... (InjuryBoard.com)

    Mixing drugs puts more older patients at risk  Dec 27, 2008
    Warfarin, a prescription blood thinner, and simvastatin, a prescription cholesterol-lowering drug: Higher risk of bleeding and rhabdomyolysis, a breakdown of muscle tissue. Lisinopril, a prescription anti-hypertension drug, and potassium, a supplement: Higher risk of abnormally high blood levels of potassium. (USA Today -- News)

    5 Dangerous Drug Combinations You Need to Avoid  Dec 27, 2008
    A new study published today in the Journal of the American Medical Association shows that 1 in 25 people in their late 50s and older is risking dangerous drug interactions by mixing, for example, the blood thinner warfarin with garlic pills ... -- warfarin and simvastatin (Zocor): increased risk of bleeding problems like bleeding ulcers, rectal bleeding, and easy bruising; also increases the possibility of statin side effects like muscle pain and muscle tissue death ... -- garlic pills and... (Yahoo News -- Top Stories)

    The great promise of personalized medicine  Dec 26, 2008
    A woman with atrial fibrillation, a heart condition, is prescribed the widely used blood-thinning drug warfarin ... In the case of warfarin, for example, adverse events related to dosage problems make this drug a leading cause of drug-related emergency room episodes. (Boston Globe)

    A prescription for problems  Dec 26, 2008
    Most major drug interactions involved non-prescription drugs, and half involved the use of anticoagulants or antiplatelet agents, such as warfarin or aspirin. A recent report estimated U.S. adults older than 65 make more than 175,000 emergency department visits annually for adverse drug events. (MSNBC)

    Older Adults At High Risk For Harmful Drug Interactions  Dec 26, 2008
    One of the most common was taking warfarin, a prescription drug designed to prevent blood clots, along with an over-the-counter drug such as aspirin, which also interferes with clotting ... Warfarin-simvastatin. (Science Daily)

    Older people mixing drugs: study  Dec 26, 2008
    More than half of the dangerous drug combinations included the use of aspirin or blood thinners such as warfarin. The most common dangerous combination of non-prescription drugs was ginkgo biloba and aspirin which can increase the risk of internal bleeding when taken together. (Yahoo News -- Pharmaceutical Industry News)

    Older People Mixing Drugs  Dec 26, 2008
    Saturday, December 27, 2008. Older people mixing drugs: study Posted: 26 December 2008 0928 hrs. (Channelnewsasia.com)

    Seniors warned of risky mixing of medicine  Dec 25, 2008
    For example, warfarin, a potent prescription clot-fighting drug, was often taken with aspirin ... Researchers said these risks also occur when warfarin is taken with garlic pills, which some studies have suggested can benefit the heart and help prevent blood clots. (San Francisco Chronicle)

    Older Americans take risky combo of medications  Dec 25, 2008
    For example, some people in the study were taking the blood thinner warfarin along with the cholesterol-lowering drug simvastatin, a combination that can increase the risk of bleeding. Others were taking warfarin and aspirin together, or ginkgo supplements with aspirin, which can also cause problems ... The most commonly used prescription and over-the-counter drugs were for treating or preventing heart disease, such as cholesterol-lowering statins, blood-pressure-lowering drugs, and blood... (CNN -- Health)

    Drug Combinations Putting Seniors at Risk  Dec 25, 2008
    The most common adverse interactions occurred with blood thinners such as warfarin and antiplatelet drugs such as aspirin, Qato's group found ... Warfarin (Coumadin) plus simvastatin (Zocor) can increase bleeding risk ... Warfarin (Coumadin) plus aspirin can increase bleeding risk. (MEDLINEplus)

    Older people mixing drugs: Study  Dec 25, 2008
    More than half of the dangerous drug combinations included the use of aspirin or blood thinners such as warfarin. The most common dangerous combination of non-prescription drugs was ginkgo biloba and aspirin which can increase the risk of internal bleeding when taken together. (India Times, India)

    Drugs firm in 1m deal on price fix allegations  Dec 23, 2008
    Scottish ministers and health boards lodged claims in the civil courts in England in February 2005 against a number of companies, in connection with forming alleged price-fixing cartels in respect of the generic drugs warfarin, ranitidine and penicillin-based drugs. Criminal charges were brought against Ranbaxy and four other drugs firms by the Serious Fraud Office in 2006 for conspiracy to defraud in relation to price fixing, but they were dismissed this month after lengthy legal argument. (Scotsman)

    Study shows optimal dose management of warfarin improves anticoagulation control  Dec 23, 2008
    Boston, MA Researchers from Boston University School of Medicine (BUSM) have determined the optimal dose-management strategy to derive maximal benefit from warfarin therapy and improve patient outcomes ... Warfarin is highly effective to prevent strokes, treat venous thromboembolism and for other conditions ... Numerous studies have focused on the underutilization of warfarin for patients with atrial fibrillation, the most common indication for warfarin. (EurekAlert!)

    A test of financial incentives to improve warfarin adherence  Dec 23, 2008
    Sub-optimal adherence to warfarin places millions of patients at risk for stroke and bleeding complications each year. Novel methods are needed to improve adherence for warfarin ... We conducted two pilot studies to determine whether a lottery-based daily financial incentive is feasible and improves warfarin adherence and anticoagulation control. (BioMed Central)

    Video: Gleevec Receives US Approval as First Treatment To Reduce Risk of Cancer Returning in Patients with Gastrointestinal Stromal Tumors  Dec 20, 2008
    Examples of commonly used drugs that may significantly interact with Gleevec include ketoconazole, acetaminophen, warfarin, erythromycin and phenytoin. (Please see full Prescribing Information for other potential drug interactions). (PR Newswire)

    Doctor censured, fined for professional misconduct, negligence  Dec 18, 2008
    Thursday, December 18, 2008. " onclick="Next();" src="/images/butt_next. (Channelnewsasia.com)

    Hepatitis C Treatment Reduces The Virus But Liver Damage Continues  Dec 16, 2008
    2, 2008) The drug warfarin may help prevent liver failure in thousands of people with Hepatitis C, according to new. . (Science Daily)

    Curry lowers high blood pressure  Dec 16, 2008
    This herb also may interact with the blood thinner Coumadin (warfarin). I've suffered with Raynaud's disease in my hands for two years. (Athens Banner-Herald)

    How Warfarin Works  Dec 13, 2008
    Warfarin is a commonly prescribed medication in America ... Warfarin (Coumadin) is the most widely used prescription anticoagulant ( blood thinner ) in the United States ... The most common uses for warfarin are for people who are undergoing surgery that may lead to clots which could migrate to the heart or lungs, those who have previously produced dangerous blood clots, or those with heart conditions that might lead to life-threatening clotting (e. (Suite101.com)

    Brand-name Drugs Do Not Appear Superior To Generic Drugs For Treating Cardiovascular Diseases  Dec 12, 2008
    Among narrow therapeutic index drugs (NTI; drugs whose effective doses and toxic doses are separated by a small difference in plasma concentration), clinical equivalence was reported in 1 of 1 RCT (100 percent) of class 1 anti-arrhythmic agents and 5 of 5 RCTs (100 percent) of warfarin ... The researchers also reported, "; we identified numerous studies that evaluated differences in clinical outcomes with generic and brand-name medications. Our results suggest that it is reasonable for... (Science Daily)

    St. John's Wort  Dec 11, 2008
    St. John s Wort interacts with a variety of medications including: oral contraceptives, warfarin, digoxin, anticonvulsants, theophylline, SSRIs (such as Paxil or Prozac), triptans, cyclosporine, anti-virals prescribed for HIV and some anti-cancer medications. References. (Suite101.com)

    Six Genetic Variants Associated With 'Bad' Cholesterol  Dec 9, 2008
    8, 2008) A new study presages a real aim of genetics: to look at whole populations to in order determine the significance of individual genetic variants for individual health. The research team, whose work is published in Nature Genetics, find six novel genetic variants that are associated with lipid levels, a common indicator of heart or artery disease. (Science Daily)

    New Phase II Data Show Safety of Once-Daily Oral Factor Xa Inhibitor, DU-176b, Comparable to Warfarin in Patients With Non-Valvular Atrial Fibrillation  Dec 8, 2008
    SAN FRANCISCO, Dec. 7 /PRNewswire-FirstCall/ -- Patients with non-valvular atrial fibrillation receiving either 30 mg or 60 mg once-daily dose of DU-176b, an investigational oral Factor Xa inhibitor, experienced comparable safety and tolerability compared to those taking warfarin, according to new Phase II data presented today at the 50th Annual Meeting of the American Society of Hematology in San Francisco ... The objective of the multinational study was to assess the safety of four dose... (PR Newswire)

    Daiichi Sankyo Initiates Phase III Trial of Its Investigational Factor Xa Inhibitor, DU-176b, in Patients With Atrial Fibrillation  Dec 8, 2008
    The Phase III global study, Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation (ENGAGE-AF TIMI 48), will compare DU-176b with warfarin in preventing stroke and systemic embolic events (SEE) in patients with atrial fibrillation ... Results from a recently presented Phase II safety study showed that the incidence of major and clinically relevant non-major bleeding events reported in the once-daily DU-176b treatment groups (30 mg or 60 mg) was similar to that in the... (PR Newswire)

    Research highlights new approaches to prevent blood clots  Dec 7, 2008
    Randomized, Parallel Group, Multicenter, Multinational Study Evaluating Safety of DU-176b Compared With Warfarin in Subjects With Non-Valvular Atrial Fibrillation [Abstract #33] Jeffrey I. Weitz, MD, Henderson Research Centre, Hamilton, Canada ... This phase II study found that two regimens (30 mg and 60 mg once-daily) of an investigational oral Factor Xa inhibitor, DU-176b, are safe in patients with non-valvular atrial fibrillation, making the drug a potential substitute for warfarin, the... (EurekAlert!)

    Generics are as good as branded drugs  Dec 4, 2008
    The study covered beta-blockers, diuretics, calcium-channel blockers, statins, antiplatelet agents, ACE inhibitors, alpha-blockers, anti-arrhythmic agents and warfarin. Text. (India Times, India -- Health/Science)

    More Than 200 Abstracts at ASH and SABCS Reveal Potential Compelling Patient Benefits From Novartis Oncology Current and Pipeline Therapies  Dec 4, 2008
    Examples of commonly used drugs that may significantly interact with Gleevec include ketoconazole, acetaminophen, warfarin, erythromycin and phenytoin ... Since warfarin is metabolized by CYP2C9 and CYP3A4, it should be avoided if possible. (PR Newswire)

    Brand-name drugs no better than generics  Dec 3, 2008
    The study covered beta-blockers, diuretics, calcium-channel blockers, statins, antiplatelet agents, ACE inhibitors, alpha-blockers, anti-arrhythmic agents and warfarin. The researchers said brand-name manufacturers have suggested generic drugs may be less effective and less safe. (MSNBC -- Health)

    'Personalized medicine' may get a boost  Nov 29, 2008
    Problems with Coumadin, also known as warfarin, are a major cause of emergency room visits for seniors. "It would be very helpful if you could get [Medicare] and FDA talking to each other," said Edward Abrahams, executive director of the Personalized Medicine Coalition. (Boston Globe)

    Obama to broaden geneticsrole in medical care  Nov 29, 2008
    Problems with Coumadin, also known as warfarin, are a major cause of emergency room visits for seniors. Don't miss this on msnbc. (MSNBC -- Health)

    14 Drugs Identified As Most Urgently Needing Study For Off-label Use  Nov 27, 2008
    Rounding out the top five were warfarin, escitalopram, risperidone and montelukast. The most common off-label use for six of the 14 drugs on the list was for bipolar disorder. (Science Daily)

    'Off-Label' Drug Use Is Common  Nov 26, 2008
    The blood thinner Coumadin (known generically as warfarin) was included in the report. The drug is widely prescribed for the treatment of hypertensive heart disease and coronary heart disease, but it is not approved for these uses. (CBS News)

    Study Calls for Greater Scrutiny Of 'Off-Label' Drug Use  Nov 26, 2008
    "Typically, drugs have to pass a number of safety tests, Walton said. "But once they are put on the market, because they have received approval for an on-label indication, they can be used off-label," he said. The new report was published in the Nov. 24 issue of the journal Pharmacotherapy. Antidepressants and antipsychotics are the most prominent classes of drugs on the list, which specifically targets medicines that have high levels of off-label use without good scientific backing. Topping the... (MEDLINEplus)

    More studies urged for off-label drugs  Nov 25, 2008
    Study: Off-label drugs should be researched for safety - USATODAY.com. Antidepressant pills Lexapro, Effexor and Zoloft are in the top 10 list of drugs that most need to be studied for off-label prescribing, according to Pharmacotherapy. (USA Today)

    Genome-wide Association Scan For Genetic Determinants Of Warfarin Dose  Nov 21, 2008
    D., a Statistical Geneticist at the Wellcome Trust Sanger Institute (Cambridge, UK), will discuss the results of new research that that he and his colleagues have recently completed which extends this genome-wide association scan (GWAS) method to investigate the genetic aspects of drug response (pharmacogenetics) related to predicting appropriate warfarin dose. Warfarin is the most widely prescribed drug used to reduce blood clotting in order to protect high-risk patients from experiencing a... (Science Daily)

    Study: Ginkgo doesnt prevent Alzheimers  Nov 19, 2008
    People on the blood thinner warfarin shouldnt take ginkgo because of the risk of increased bleeding. More on. (MSNBC -- Health)

    Ginkgo fails to prevent Alzheimer's in large study  Nov 19, 2008
    People on the blood thinner warfarin shouldn't take ginkgo because of the risk of increased bleeding. Proponents claim ginkgo protects the brain by preventing the buildup of an Alzheimer's-related protein or by preventing cell-damaging oxidative stress. (Honolulu Advertiser)

    Genetic disease treatments and pharmacogenetics: From scientific discovery to medical delivery  Nov 15, 2008
    The presentations included in this press briefing will report on: the results of a genome-wide association scan for genetic determinants of warfarin dosage, breakthrough research on a new treatment that has the potential to be the first successful therapy for Huntington's Disease, a long-term study on a successful enzyme replacement therapy for children with Type I Gaucher Disease, and new research findings that offer important new clues that will facilitate more precise and compartment-specific... (EurekAlert!)

    Chad Mirkin: Thinking Big  Nov 15, 2008
    It has received approval from the U.S. Food Administration for a genetic sensitivity test to the blood-thinner warfarin, known under its commercial name Coumadin. It also has tests in advanced development for cystic fibrosis, influenza, and human papillomavirus. (BusinessWeek)

    Shortness of breath cuts quality of life  Nov 14, 2008
    His heartbeat was rapid, so he takes warfarin to prevent a stroke. He has his levels monitored every few weeks. (Taylor Daily Press, TX)

    The management of non-valvular atrial fibrillation (NVAF) in Australian general practice: bridging the evidence-practice gap. A national, representative postal survey.  Nov 14, 2008
    As part of a larger survey assessing GP management of NVAF, we included questions to explore GPs' risk assessment, estimates of stroke risk and GPs' perceptions of the risks and benefits of anticoagulation with warfarin ... The majority of GPs recognised that the benefits of warfarin outweighed the risks for three case scenarios in which warfarin is recommended according to Australian guidelines ... 0% (n=131) would be "highly likely" or "likely", respectively, to cease warfarin therapy and... (BioMed Central)

    Written Instructions Cut Bleeding Risk for Blood Thinner Use  Nov 11, 2008
    SATURDAY, Nov. 8 (HealthDay News) -- Giving patients written and verbal instructions on proper use of the blood thinner warfarin significantly reduces the risk of serious gastrointestinal and brain bleeding problems, according to a University of Pennsylvania School of Medicine study ... The study included 2,346 older adults taking warfarin for problems such as heart rhythm abnormalities, deep vein thrombosis, stroke, heart valve replacements or pulmonary embolism ... The findings, published in... (MEDLINEplus)

    Cranberries, Coumadin don't mix  Nov 11, 2008
    Trying to maintain a steady anticoagulant effect from Coumadin (warfarin) can be a little like walking a tightrope ... Several cases in Great Britain led the health authorities there to warn against combining cranberries or cranberry juice with the anticoagulant Coumadin (warfarin) ... Australian scientists have reported that cranberry significantly increases warfarin's anticoagulant effect (British Journal of Pharmacology, August 2008). (Athens Banner-Herald)

    J&J's High-Wire Heart Drug  Nov 11, 2008
    A few years back, AstraZeneca (nyse: - - ) thought it had developed a replacement for warfarin, the notoriously tricky-to-use blood thinner, but it fell through when the compound was linked to serious liver problems. Rivaroxaban, the J, is essentially another attempt to come up with a better warfarin ... It has already successfully completed trials to prevent vein clots in patients after orthopedic surgery and is also being tested as a replacement for warfarin in atrial fibrillation patients. (Forbes -- Business)

    Presentations at AHA expand on clinical utility of deCODE's DNA-based tests  Nov 8, 2008
    This strengthens the case for going beyond standard cardiac monitoring, for hospitalized and discharged patients who have suffered stroke or transient ischemic attack (TIA), and for the prescription of warfarin, rather than Plavix or aspirin, for those with AF. deCODE will also present data on the utility of deCODE AF for detecting recurrent AF.. Researchers from Cleveland Clinic have conducted their own study of the link between the 4q25 markers and AF, and will look at correlations between... (EurekAlert!)

    FDA Warns of Dangers of Mexican Vanilla  Nov 4, 2008
    Coumarin is related to warfarin, which is found in some blood thinners. Eating foods with coumarin may be dangerous for people taking blood thinners, because the combination could increase their risk of bleeding. (MEDLINEplus)

    DNA Research Taking Guesswork Out Of Finding The 'Therapeutic Window'  Oct 29, 2008
    At the top of the list of problem drugs is Warfarin, (Coumadin), the most widely prescribed anticoagulant ... In this case, they re trying to find the correlation between genotypes, or a person s inner code of DNA, and the correct dosage of Warfarin ... That would allow doctors to prescribe the correct dosage of Warfarin and decrease the risk of adverse drug reactions: Too low a dose can increase the risk of dangerous blood clots, while too large can cause life-threatening bleeding. (Science Daily)

    How to Tell if a Dog Has Eaten Rat ...  Oct 25, 2008
    How to Tell if a Dog Has Eaten Rat Poison: Rat Poisoning Symptoms in Dogs, Signs of Warfarin Toxicity ... Rat Poisoning Symptoms in Dogs, Signs of Warfarin Toxicity ... Rat poison is a rodenticide containing the toxin warfarin, which causes symptoms like hemorrhaging and internal bleeding in dogs. (Suite101.com)

    Improving the Use of Drugs Through Genes  Oct 24, 2008
    San Francisco-based DNA Direct tests for the genes that determine a patient's response to warfarin, a blood thinner. Since not enough drug in the blood increases the risk of clots while too much can lead to dangerous bleeding, there is urgent need for a test to help pinpoint the right starting dose. (Yahoo News -- Pharmaceutical Industry News)

    Preventing DVT  Oct 21, 2008
    The usual treatment for DVT involves using the anticoagulant medicines, heparin and warfarin. Tips for Travelling. (Suite101.com)

    Needle Breast Biopsy Safe with Blood Thinner  Oct 21, 2008
    Somerville and colleagues studied 200 women who were taking blood thinners such as aspirin or warfarin and 855 women who were not ... "The take-home message is that patients on aspirin or warfarin therapy can safely undergo breast needle core biopsy without going off their medications," Somerville said. (MEDLINEplus)

    Warfarin Underused in Atrial Fibrillation Patients  Oct 16, 2008
    TUESDAY, Oct. 14 (HealthDay News) -- A new study reports that warfarin, a common treatment for atrial fibrillation, is either not prescribed by U.S. doctors as often as it could be or, when it is, not at optimal therapeutic doses ... While warfarin can be effective in managing AF, use of the anticoagulant can also cause bleeding ... It found that less than half of almost 117,000 AF and atrial flutter patients between 1999 and 2005 were on warfarin. (MEDLINEplus)

    Oracle database in the cloud floated at Harvard lab  Oct 15, 2008
    Tonellato and the Laboratory for Personalized Medicine (LPM) are using cloud computing services to run virtual clinical trials on a drug called Warfarin, used on patients at risk for blood clots ... Tonellato has created clinical avatars of patients using genetic background information and has now tested Warfarin dosing on close to 100 million of the virtual patients ... Tonellato and the Laboratory for Personalized Medicine (LPM) are using cloud computing services to run virtual clinical trials... (SearchOracle.com)

    Racial Differences For Brain Bleeds Suggest Stroke Risk Greater Than Thought For Blacks  Oct 8, 2008
    1, 2008) A new study shows that people who take the commonly used blood thinning drug warfarin may have larger amounts of bleeding in the brain and increased risk of death if they suffer a hemorrhagic. (May 13, 2007) Patients with a hemorrhagic stroke are significantly less likely to receive medications and counseling to prevent recurrent strokes compared to patients with an ischemic. (Science Daily)

    Core Needle Breast Biopsy Safe For Patients Taking Blood Thinners  Oct 7, 2008
    Our study demonstrates that it is safe to perform core needle biopsies on patients taking aspirin and warfarin (another name for coumadin). Patients can remain on their medications and avoid surgical biopsy if the lesion is benign, said Dr. Somerville. (Science Daily)

    Blood Thinner Linked to Increased Brain Bleeding  Oct 3, 2008
    MONDAY, Sept. 29 (HealthDay News) -- The amount of bleeding in the brain that occurs when a blood vessel bursts and causes a stroke is greater for some people who take the clot-preventing drug warfarin (Coumadin), a new study shows. It's not a surprising finding, said Dr. Daniel Woo, an associate professor of neurology at the University of Cincinnati and co-author of the report in the Sept. 30 issue of Neurology, since it's long been established that the risk of death from such a stroke is... (MEDLINEplus)

    Alert Issued on Use of Blood Thinners  Sep 25, 2008
    The new alert focuses specifically on low-molecular weight heparin, warfarin and low-molecular weight enoxaparin ... Heparin and warfarin have consistently ranked among the 10 most frequently reported drugs ... Heparin, warfarin and enoxaparin were associated with the most errors. (U.S. News & World Report)

    Regulator says hospitals need strict heparin rules  Sep 24, 2008
    Warfarin, another blood thinner cited in the alert, is available in pills patients can take at home but can cause bad reactions when mixed with other medicines. The recommendations "absolutely" will make a difference and hospitals will pay attention, said James Conway, senior vice president of the nonprofit Institute for Healthcare Improvement in Cambridge, Mass. (Albany Times Union)

    Study Helps Stop Drugs Slipping Through Safety Net  Sep 20, 2008
    Side effects can be caused by many factors relating to drug transport, immune response, and sometimes unexpected metabolic pathways, but as Pirmohamed noted, they fall into two main categories, type A and type B. "The majority (80-90%) of adverse drug reactions are type A they are predictable from the known pharmacology of the drug, are dose-dependent, and can be alleviated by reducing or identifying the correct dose for the patient," said Pirmohamed, who gave the example of the anti-coagulant... (Science Daily)

    Newest Interventional Radiology Treatment Used To Bust Blood Clots In Legs  Sep 17, 2008
    25, 2003) A study of long-term, low-dose warfarin to prevent the recurrence of the blood clotting disorders deep vein thrombosis (DVT) and pulmonary embolism resulted in such a high degree of benefit to the. . (Science Daily)

    Your Health: Warfarin is a lifesaving drug, but interacts with many other drugs (110)  Sep 13, 2008
    Your Health: Warfarin is a lifesaving drug, but interacts with many other drugs ... Q:I have atrial fibrillation, an abnormal heart rhythm, for which I take Tambocor (a heart rhythm drug) and warfarin (a blood thinner) ... I think the Tylenol was affecting the warfarin, because after I stopped taking it, my bleeding time results came back into balance. (Sioux Falls Tri-State Neighbor, SD)

    Tennis mom worries about sunscreen safety  Sep 9, 2008
    This aspirinlike drug could well interact with the blood thinner warfarin (Coumadin). Such a combination could increase the risk for bleeding. (Athens Banner-Herald)

    FDA posts list of potential problem drugs  Sep 6, 2008
    Stromectol and Warfarin, an anti-parasite drug and a blood thinner, drug interaction. Tykerb, for advanced breast cancer, liver damage. (MSNBC -- Health)

    New Drug Protects Against Second Heart Attack Or Stroke, Study Suggests  Sep 6, 2008
    Most are prescribed aspirin, clopidogrel (also known as Plavix or Iscover) and/or warfarin. "Warfarin is clearly effective as an anticoagulant, but it is especially hard to manage properly and safely," Alexander said ... "What's driving research in this area is the fact that although aspirin and clopidogrel both offer heart attack patients important protection against blood clots, there is still room for improvement. Studies show that a significant number of patients taking aspirin and... (Science Daily)

    ON THE WEB: See the FDA list  Sep 6, 2008
    Ivermectin (Stromectol) and Warfarin. Drug interaction. (USA Today -- Money)

    Most Patients with Irregular Heartbeat Take Inadequate Blood Thinner Dose  Aug 30, 2008
    Warfarin could cut stroke risk by 67%, but patients and doctors say drug is hard to manage ... THURSDAY, Aug. 28 (HealthDay News) -- Only 40 percent of patients with atrial fibrillation, a known risk factor for stroke, who did suffer a stroke were taking the anti-clotting drug warfarin, a new study found ... Among those taking warfarin, 75 percent weren't getting the dose needed to prevent a stroke. (MEDLINEplus)

    Aciphex (Rabeprazole)  Aug 27, 2008
    Be sure to inform your doctor if you take blood thinners such as Coumadin (warfarin), Nizoral (ketoconazole) or medication containing cyclosporine such as Sandimmune or Neoral. Pregnancy and Aciphex. (Suite101.com)

    Finding May Allow Some Women to Stop Blood Thinners  Aug 26, 2008
    Current guidelines call for indefinite use of a clot-preventing drug, most often warfarin (Coumadin), for many people with the condition. But researchers report that they've identified a group of traits in women that indicate a very low risk of recurrent clots, so that medication might not be necessary after a few months. (MEDLINEplus)

    Drug Error Rate Low for Assisted Living Patients  Aug 26, 2008
    The researchers did find that errors were more likely to occur with riskier medications, like insulin or the blood thinning drug warfarin, which are typically given to patients "in less stable and predictable conditions.". They suggest that prioritizing the administration of high-risk drugs, as well as the care of patients with more complex health issues, could help prevent serous medication errors and improve the quality of care. (MEDLINEplus)

    Women May Stop Anticoagulants After Blood Clots, Research Suggests  Aug 26, 2008
    "It may be safe for women who have taken oral anticoagulants for 5-7 months after an unprovoked venous thromboembolism to discontinue therapy if they have 0 or 1 of the following: hyperpigmentation (brown discoloration), edema (swelling) or redness of either leg; a D-dimer level (blood clotting test) of 250ug/L or more while taking warfarin, BMI [body mass index] 30kg/m2; and aged 65 years or more,". conclude Dr. Marc Rodger and coauthors. (Science Daily)

    Pharmacogenomics and Drug Toxicity  Aug 21, 2008
    Examples of adverse drug reactions in this group include hypoglycemia induced by diabetic drugs, leukopenia induced by cytotoxic anticancer drugs, and bleeding induced by warfarin, an oral anticoagulant. The phenotypes of the second group are not explained by the mode of action of the drug. (New England Journal of Medicine)

    Atritech looking for approval on heart device  Aug 19, 2008
    We are thrilled to have completed this expansive and important trial and delighted to be one step closer to providing patients a compelling alternative to warfarin therapy. Reader Comments. (Twin Cities Business Journal, MN)

    Black market drugs 'health risk'  Aug 13, 2008
    He added: "Warfarin sometimes masquerades as Diazepam 10mg - for someone who doesn't need Warfarin, it could be fatal as you could bleed to death. "My plea is to anyone who feels they want these medicines, do not buy them from illegal sources, it's much too dangerous. " Drugs programme manager Benny Lynch of the Falls Community Council said the addiction problem is "massive," with "as many people on these tablets now as there were during the Troubles". He said he knew of one group of women in... (BBC News -- UK)

    Liver Damage In Hepatitis C Patients Could Be Treated With Warfarin, Says New Study  Aug 3, 2008
    2, 2008) The drug warfarin may help prevent liver failure in thousands of people with Hepatitis C, according to new research ... In a study published tomorrow (1 August) in the Journal of Thrombosis and Haemostasis, researchers show that warfarin reduces the scarring on the liver caused by Hepatitis C. This scarring, or fibrosis, replaces normal liver cells and can lead to cirrhosis of the liver and ultimately liver failure ... Following the new findings in mouse models, the Imperial College... (Science Daily)

    St. John's Wort Labels Often Lack Safety Warnings  Jul 31, 2008
    But taking the herb with AIDS medications or with drugs that suppress the immune system, or with oral contraceptives, or the blood-thinning drug warfarin can reduce the effectiveness of these drugs, Clauson and colleagues note in the journal BMC Complementary and Alternative Medicine. St. John's wort is also not recommended for people with bipolar illness or those taking prescription antidepressants. (MEDLINEplus)

    Why is My Pet Peeing Blood?  Jul 22, 2008
    Poisoning: Certain toxins, like warfarin, which is contained in rat and mouse poisons, causes internal bleeding and a lack of blood clotting. Frequent urination and urinating blood is among the constellation of symptoms that s seen in a pet who has been poisoned. (Suite101.com)

    U.S. Federal Circuit Court of Appeals Rules Patent for ACIPHEX(R) Valid and Enforceable  Jul 22, 2008
    Patients on warfarin (such as Coumadin(R)) may need to be monitored closely by their doctor. For more information, visit. (PR Newswire)

    U.S. Federal Circuit Court of Appeals Fully Upholds Eisai's Favorable Ruling in Aciphex(R) Patent Infringement Lawsuit Against Teva Pharmaceuticals and Dr. Reddy's Laboratories  Jul 22, 2008
    Patients on warfarin (such as Coumadin(R)) may need to be monitored more closely by their doctor. To learn more, talk to your doctor and see the full product information at. (PR Newswire)

    Deep Vein Thrombosis and Prostate C...  Jul 19, 2008
    As Gardner began nine weeks of radiation for prostate cancer, he also started a regimen of 3-6 months on warfarin, a blood thinner, for the DVT. ... But the warfarin only thins the blood, it doesn t dissolve the clot. (Suite101.com)

    Administering Heparin Soon After Stroke Can Increase Risk Of Serious Bleeding  Jul 17, 2008
    However, it appears that anticoagulation with warfarin therapy may safely begin shortly after stroke ... Warfarin sodium, commonly prescribed for this purpose, takes several days to reach therapeutic levels and so is often combined (bridged) with other therapies ... Of these, eight received no anti-clotting therapy; 88 received aspirin only; 35 were given aspirin and warfarin; 44 received intravenous heparin and warfarin; and 29 were treated with a full dose of enoxaparin, a... (Science Daily)

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