Valsartan and Recurrent Atrial Fibrillation Jul 30, 2009
To the Editor: Disertori et al. (April 16 issue)1 describe the effects of valsartan on the recurrence of atrial fibrillation. The disappointing results of the trial may be explained by two important limitations. (New England Journal of Medicine)
Blood Pressure Drug May Not Ease Irregular Heartbeat Apr 17, 2009
Despite earlier promise, valsartan fails to deliver against atrial fibrillation, researchers say ... WEDNESDAY, April 15 (HealthDay News) -- The blood pressure drug valsartan may not prevent episodes of a dangerous abnormal heart rhythm called atrial fibrillation, an Italian study finds ... Earlier research had suggested that valsartan (Diovan) might reduce the occurrence of atrial fibrillation, a faulty heartbeat that can lead to the formation of clots that can cause heart attack or stroke. (MEDLINEplus)
Valsartan for Prevention of Recurrent Atrial Fibrillation Apr 16, 2009
Methods We conducted a large, randomized, prospective, placebo-controlled, multicenter trial to test whether the ARB valsartan could reduce the recurrence of atrial fibrillation ... Patients were randomly assigned to receive valsartan or placebo ... 4%) in the valsartan group, as compared with 375 of 720 (52. (New England Journal of Medicine)
