Flu Bugs Growing Resistance to Drugs May 21, 2008
Doctors had hopes for two newer drugs -- Roche AG's Tamiflu, known generically as oseltamivir and licensed from Gilead Sciences, and GlaxoSmithKline's Relenza, known generically as zanamivir. But already resistance is being seen to Tamiflu, a pill that can be taken to treat symptoms and also to prevent infection. (MEDLINEplus)
Multiple meds needed to stop bird flu pandemic May 15, 2008
Tamiflu, known generically as oseltamivir, and Relenza, or zanamivir, target the viral protein neuraminidase, which helps release newly-made viruses so that they can spread infection. Using a technique called X-ray crystallography, Gamblin and colleagues examined the exact mutation in protein structure that can make some flu virus resistant to Tamiflu and showed the different nature of Relenza meant it was still effective. (MSNBC -- Health)
International symposium reports on the use of antivirals in patients with H5N1 Mar 4, 2008
MISSISSAUGA, ON, March 4 /CNW/ - Physicians from countries affected by the deadly H5N1 influenza virus (bird or avian flu) have presented case reports about antiviral use in patients infected with H5N1, including treatment with the oral antiviral TAMIFLU(R) (oseltamivir) ... Susceptibility of circulating H5N1 strains to TAMIFLU These clinical findings are supported by animal data, also presented at ISRVI, which shows that oseltamivir treatment was effective against H5N1 influenza viruses... (Canada Newswire)
Whole new flu vaccine needed next year: WHO Feb 16, 2008
Four antiviral drugs can help treat a case of the flu, but the WHO said H1N1 viruses in 18 countries had developed mutations that made them resist the effects of the best drug, Tamiflu, or oseltamivir, made by Roche AG and Gilead Sciences. Resistance to the older drugs, amantadine and rimantadine, is now so widespread that their use is no longer recommended. (Scientific American)
Drug Resistant Influenza Feb 14, 2008
Made in Switzerland by Roche and referred to medically as oseltamivir, it is an antiviral medication widely used to treat viral flu ... In addition to oseltamivir, three additional drugs are FDA approved for treating the flu. (Suite101.com)
Flu Kills 2 Children, Is an Outbreak Headed to Your... Feb 12, 2008
7 percent have been found to be resistant to Tamiflu (oseltamivir), an antiviral medication that has been shown to shorten the duration of the flu when taken within two days of infection. Similar percentages of the drug-resistant strain were also found in Europe and Canada. (Fox News)
What next for bird flu in Jakarta? Feb 12, 2008
No researcher has found proper vaccines to prevent bird flu, with evidence suggesting the H5N1 virus is resistant to the medication used to treat it -- oseltamivir. European public health specialists have also identified that the H5N1 virus is significantly resistant to the drug Tamiflu, which is the world's most widely purchased influenza medicine. (Jakarta Post, Indonesia -- City)
Pawar tells states to lift curbs on poultry movement Feb 11, 2008
Under the bird flu preparedness plan, the ministry had decided to stockpile 10 lakh capsules of oseltamivir at any given point of time. WHO has, however, stockpiled three million doses of Tamiflu. (Times of India)
CDC says influenza B strain doesn't match vaccine Feb 9, 2008
In late January, the European Centre for Disease Prevention and Control sounded a warning that some H1N1 influenza viruses in Europe were showing signs of oseltamivir (Tamiflu) resistance ... 3% (8 of 128) Canadian isolates showed signs of oseltamivir resistance ... Bresee said the CDC is watching the oseltamivir-resistant viruses very closely and that investigators still don't know what caused the mutation. (CIDRAP)
Australia, Hong Kong report Tamiflu-resistant flu Feb 8, 2008
The WHO said that it was still gathering global data about "an increased number of (seasonal) H1N1 viruses with resistance to oseltamivir" following the first reports which emerged in Europe in late January. Oseltamivir is the generic name for Tamiflu, made by Switzerland's Roche Holding AG and Gilead Sciences Inc of the United States, which governments worldwide have been stockpiling as a first line of defence in case the bird flu virus sparks a human influenza pandemic. (Guardian Unlimited)
Tamiflu Resistance Among Some Influenza Flu Virus Samples In Europe Feb 3, 2008
A European survey has issued preliminary results which show flu virus resistance to oseltamivir (Tamiflu) ... The EU-funded VIRGIL network has tested 437 samples of the A (H1N1) flu virus strain between November 2007 and January 2008 in 18 European countries - of which 59 from nine different countries have become resistant to oseltamivir, 26 of them from Norway out of 37 that were sent for testing (in Norway) ... Norwegian authorities, as soon as this high level of resistance to oseltamivir in... (Medical News Today)
Drug-resistant flu found in Europe Feb 2, 2008
"If I had only a single drug to choose for influenza, oseltamivir (Tamiflu) is the one I would go for," said Dr. Angus Nicoll, influenza coordinator for the European Centre for Disease Prevention and Control. Tamiflu, made by Roche Holding AG, has been stockpiled by WHO and by countries around the world for possible use in a flu pandemic. (Atlanta Journal-Constitution)
Drug-Resistant Flu Virus on the Rise Feb 1, 2008
More than 10% of virus samples taken in Western Europe this winter were resistant to oseltamivir, better known as Tamiflu, according to figures from the European Centre for Disease Prevention and Control (ECDC). Nearly 10% of the samples in Canada were resistant too, according to national authorities there, and the U.S. found nearly 7% resistance. (TIME)
* Scientists surprised by influenza virus resistant to Tamiflu Feb 1, 2008
There are no immediate plans to recommend changes in the use of Tamiflu, which is also known as oseltamivir, officials from WHO and the US said in interviews, because the incidence of the mutant virus is still small. Tamiflu is one of the antiviral drugs used to treat influenza in its early stages. (Taipei Times, Taiwan -- Business)
Mutant flu virus is found that resists popular drug Jan 31, 2008
There are no immediate plans to recommend changes in the use of Tamiflu, which is also known as oseltamivir, officials from the WHO and the United States said in interviews, because the incidence of the mutant virus is still small. Tamiflu is one of the antiviral drugs used to treat influenza in its early stages. (International Herald Tribune)
Some ordinary flu strains are resistant toTamiflu Jan 29, 2008
Of 16 samples from Norway, 12 tested positive for resistance against Tamiflu, which is also known by the generic name oseltamivir, Stockholm-based ECDC said ... "Given the initial indication of a high level of resistance to oseltamivir in the A H1N1 viruses circulating in Norway, late last week ... the Norwegian authorities notified their EU partners and the World Health Organization (WHO) of this situation," the ECDC said ... "However from the limited data, the proportion of influenza viruses... (MSNBC -- Health)
High number of Tamiflu-resistant viruses found Jan 29, 2008
Most of the cases of resistance have occurred in people who were not treated with Tamiflu (oseltamivir), a fact that suggests viruses with this mutation may be more capable of spreading from person to person than had been previously thought. It had been believed that viruses that acquired this resistance mutation would pay for that gain with a corresponding loss in their ability to transmit that it would make them less able to compete with unaltered viruses in the race to infect and spread among... (Globe and Mail)
Experts probe high bird flu mortality rate in Indonesia Jan 25, 2008
He said a major concern was the H5N1 variant in Indonesia appeared to be less susceptible to oseltamivir, the antiviral used to combat the disease ... Studies are being conducted in Thailand, Vietnam and Indonesia to see if H5N1 patients need to be given higher dosages of oseltamivir. (Reuters)
Bird Flu May Be Spread Indirectly, WHO Says Jan 19, 2008
It is made by Roche Holdings AG and Gilead Sciences under the generic name oseltamivir. Reuters Health. (MEDLINEplus)
Antiviral Therapy Cuts Deaths from Severe Flu Dec 27, 2007
Roughly one-third of the subjects received antiviral therapy, most commonly Tamiflu (also known as oseltamivir). According to the investigators, treatment with an antiviral reduced the risk of death within 15 days of symptom onset by about 80 percent. (MEDLINEplus)
Large bird flu cluster emerges Dec 18, 2007
These collections can mask the spread of H5N1 because oseltamivir can lower viral RNA to levels below detection. Follow-up on H5 antibody levels in these patients would be useful for determining the extent of H5N1 spread among patients and contacts. (Nature News Service)
Physical Barriers May Be More Effective Than Drugs To Prevent Pandemics Dec 3, 2007
23, 2007) Stockpiling large amounts of oseltamivir (Tamiflu) and related antiviral drugs with the intent to treat a large fraction of the population is a key part of pandemic preparedness of many countries. . (Science Daily)
FDA Panel Backs Tougher Warning for Tamiflu Nov 29, 2007
TUESDAY, Nov. 27 (HealthDay News) -- A U.S. Food and Drug Administration advisory panel recommended Tuesday that the prescription flu drug Tamiflu (oseltamivir) should have a stronger warning label to reflect reports of bizarre behaviors and deaths among children who use the medication. The FDA's Pediatric Advisory Committee, in a 9-5 vote, said that drug maker Roche Holding AG should change its prescribing information because it doesn't adequately explain side effects reported by hundreds of... (MEDLINEplus)
Tamiflu And Relenza Should Have Psychiatric Side Effects Warning ... Nov 25, 2007
Tamiflu (oseltamivir) is a pill, while Relenza (zanamivir) is inhaled. Reports from Japan indicate that children, particularly, may have a higher risk of experiencing these psychiatric side effects after receiving the flu drugs. (Medical News Today)
Psych warning for two flu drugs: FDA Nov 25, 2007
Tamiflu, known generically as oseltamivir, is a pill, while Relenza, generically zanamivir, is inhaled. A Roche spokesman said no causal relationship between Tamiflu and these psychiatric events has been proven. (Sydney Morning Herald)
Early Tamiflu Treatment Helps Kids with Influenza Nov 24, 2007
NEW YORK (Reuters Health) - Expeditious treatment with the anti-viral drug Tamiflu, known generically as oseltamivir, can markedly reduce the duration of illness, symptom severity, and complications in children with influenza, according to study findings presented earlier this month at the World Society for Pediatric Infectious Disease meeting in Bangkok. This is "the first time that a dramatic reduction in influenza severity duration, complications and antibiotic use" has been shown when... (MEDLINEplus)
Tamiflu effective for treatment and prevention of influenza in children 1 year and older Nov 16, 2007
Tamiflu (oseltamivir) significantly reduces illness severity and duration in children one year and older, particularly if given within 24 hours of symptom onset, according to new data presented at the World Society for Pediatric Infectious Disease (WISPID) meeting in Bangkok 15-18 November ... In addition this season smaller child sized Tamiflu (oseltamivir) capsules of 30 mg and 45 mg doses will be available to provide easier and more convenient dosing by parents ... Its reassuring that... (EurekAlert!)
Antivirals Reduce Deaths From Flu In Hospitalized Patients Nov 13, 2007
This study was funded by a grant from Hoffmann-La Roche Ltd., manufacturer of the antiviral drug oseltamivir, which was used in the study. Hoffman-La Roche had no role in the design or conduct of the study; in the collection, management, analysis or interpretation of the data; or in the preparation, review or approval of the manuscript. (Science Daily)
There's no shortage of the vaccine this year, so roll up your sleeve Nov 8, 2007
There are two antiviral medications recommended by the Centers for Disease Control and Prevention: Oseltamivir (Tamiflu), which is recommended for people ages 1 and older, and zanamivir (Relenza), recommended for people ages 7 and older. These medications are appropriate for individuals who cannot receive the flu vaccine because of an allergy or other reasons, and people who are particularly vulnerable to complications from the flu, said Mitchel Rothholz, chief of staff of the American... (The Daily Reflector)
UN Expert Says World Unprepared for Avian Flu Pandemic Oct 25, 2007
But, I will tell you one thing: being prepared for a pandemic will help countries to be prepared for other mega-catastrophes, not just those that are due to infectious disease," said Dr. Nabarro. A chicken vendor waits for customers at a market in Jakarta, 16 August 2007The World Health Organization reports bird flu has spread to about 60 countries and territories. It says the H5N1 virus appears to be entrenched in the poultry populations of Indonesia, northern Egypt and parts of Nigeria,... (Voice of America)
Tamiflu Survives Sewage Treatment Oct 5, 2007
Swedish researchers have discovered that oseltamivir (Tamiflu); an antiviral drug used to prevent and mitigate influenza infections is not removed or degraded during normal sewage treatment ... The Swedish research group demonstrated that oseltamivir, the active substance in Tamiflu, passes virtually unchanged through sewage treatment ... The Swedish research group also revealed that the level of oseltamivir discharged through sewage outlets in certain countries may be so high that influenza... (Science Daily)
* Overuse of Tamiflu could give rise to resistant flu strain Oct 4, 2007
Tamiflu, whose lab name is oseltamivir, is not a cure for flu but can ease its symptoms, thus aiding vulnerable patients such as the elderly and reduce the time of illness, thus easing the burden on caregivers. Scientists led by Jerker Fick, a chemist at Umea University, tested the survivability of the Tamiflu molecule in water drawn from three phases in a typical sewage system. (Taipei Times, Taiwan -- World)
Treatment with Convalescent Plasma for Influenza A (H5N1) Infection Oct 4, 2007
Treatment with 150 mg of oseltamivir twice daily was started at 2 a.m. on June 12 (Figure 1). After 2 days. (New England Journal of Medicine)
Researchers warn about overprescribing Tamiflu Oct 3, 2007
Tamiflu, known generically as oseltamivir, was having lackluster sales as a drug to prevent and treat seasonal flu until it was the first treatment to show real efficacy in helping people with bird flu ... In their study, the Swedish team said low levels of oseltamivir, the active substance in Tamiflu, passed virtually unchanged through basic sewage treatment processes ... These birds could encounter oseltamivir in high enough concentrations to develop resistance to flu viruses they carry, the... (Scientific American)
Symptoms & Prevention of Influenza Oct 1, 2007
There are antiviral medications for the flu, including oseltamivir (Tamiflu) and zanamivir (Relenza). Amantadine and rimantadine are also treatment options, but there is increasing resistance to these medications. (Suite101.com)
Indonesia to start producing tamiflu Sep 12, 2007
JAKARTA, Sept. 11 (Xinhua) -- Indonesia will start producing oseltamivir (tamiflu), an anti-bird flu medicine, in an adequate amount this year in anticipation of the possibility of a further spread of the bird flu virus, a senior official said on Tuesday. The drug would be produced in an adequate quantity so the country no longer needed to import it, Antara news agency quoted Coordinating Minister for People's Welfare Aburizal Bakrie as saying in Denpasar, the capital city of Bali province. (Xinhuanet, China)
2 bird flu positive cases dead in Bali, Indonesia Aug 27, 2007
There has not been effective drug for AI. The recent one is oseltamivir, which only functions to obstruct virus growth. The only effective way is by preventing AI virus infection. (SpiritIndia)
Updated WHO bird flu (H5N1) management guidance reinforces Tamiflu as first line treatment Aug 23, 2007
BASEL 23 August 2007: The World Health Organization (WHO) has reinforced that Tamiflu (oseltamivir) is the primary recommended antiviral of choice in managing patients infected with H5N1 in updated guidance published on the WHO website today ... Experiences clearly show that to reduce mortality patients should receive treatment with oseltamivir as early as possible, but treatment remains effective even when patients present late, commented Professor John Oxford, Professor of Virology at St... (EurekAlert!)
Woman's death marks Bali's first H5N1 case Aug 14, 2007
She came down with a fever and cold 3 days ago and is receiving oseltamivir (Tamiflu). Although avian flu is endemic in birds in Jambrana district and other parts of Indonesia, the country's last official outbreak report was filed in October 2006, according to the United Nations Food and Agriculture Organization (FAO). (CIDRAP)
Flu strain same as last year's: H5N1 Aug 8, 2007
All are healthy," said Vineet Chawdhry, joint secretary, ministry of health. He said the country had ample oseltamivir in stock.. (Hindustan Times)
That virus again Aug 2, 2007
Though many people argue against preventive vaccination, usually on the plea that it might lead to the development of immunity in the virus against the available infection inhibitors (oseltamivir and zanamivir), nothing of the sort has happened in countries like Vietnam which have tried this solution. The other argument against vaccination, that it might hurt poultry exports, is equally untenable as several other poultry product-exporting countries have also been using the vaccine. (Business Standard)
Bird flu strikes Manipur Jul 26, 2007
Initial supplies of personal protective equipment and Oseltamivir have been rushed to the state. Though no human cases have been detected so far, a team of experts comprising microbiologists and epidemiologists has been sent to Manipur. (Business Standard)
Bird flu outbreak notified in Imphal, eastern India Jul 26, 2007
The 21 family members in a cluster of three houses and 9 veterinary staff who got exposed to the infected birds have been put under Oseltamivir chemoprophylaxis ... A team of 20 doctors would monitor the health status of cullers who would be on oseltamivir chemoprophylaxis ... 5000 capsules of Oseltamivir, 2000 sets of personal protective equipments, 1000 sets of N-95 masks and 2 ventilators have been airlifted to Imphal. (SpiritIndia)
Tamiflu(R) 30 mg and 45 mg Capsules Approved by U.S. Food and Drug Administration Jul 3, 2007
NUTLEY, N.J., July 2 /PRNewswire/ -- Roche announced today that the U.S. Food and Drug Administration (FDA) has approved a supplemental new drug application (sNDA) to market Tamiflu(R) (oseltamivir phosphate) capsules in 30 mg and 45 mg doses ... The method of manufacturing will remain the same; the only change will be the size of the capsule and the amount of the active ingredient, oseltamivir phosphate, filled into the capsule. (PR Newswire)
Earlier Initiation of Tamiflu(R) Treatment Improves Clinical Benefits for Children With Influenza Jun 23, 2007
New Data Presented Today Show Benefits of Early Treatment in Reducing Illness Duration, Symptom Severity dary Complications TORONTO, June 22 /PRNewswire/ -- A new retrospective analysis of a pivotal pediatric study indicates that earlier initiation of treatment with Tamiflu(R) (oseltamivir phosphate) is associated with greater reduction in illness duration, symptom severity and secondary complications in children with influenza ... Researchers at Roche, which makes Tamiflu, collaborated with... (PR Newswire)
Experts predict Tamiflu could halve the pandemic influenza death toll versus no intervention Jun 23, 2007
BASEL 22nd June 2007 -- Treatment with the oral antiviral Tamiflu (oseltamivir) and prophylaxis for people exposed to infected patients could be one of the most cost-effective strategies for reducing illness and death during an influenza pandemic. According to modelling research presented by Beate Sander, University of Toronto, Canada, a stockpile of Tamiflu sufficient to cover 65% of a countrys population could cut deaths by approximately half. (EurekAlert!)
Indonesian bird flu Tamiflu resistant Jun 22, 2007
Dr. Frederick Hayden says a lot of factors can have an impact on whether oseltamivir treatment of H5N1 patients is successful, including how much time passes between infection and the start of drug therapy. Search the News Search. (Globe and Mail)
Are we missing the forest in the bird flu fight? Jun 19, 2007
The public neither has the access to check the stockpile of the wonder drug oseltamivir, nor time to do so, but they may want to know where the pills are available in non-referral hospitals. Are hospitals, regardless of their classes, and doctors, regardless of their specialties, on alert for bird flu cases. (Jakarta Post, Indonesia -- Editorial)
Doctor Advises Caution Over Flu Drug Jun 17, 2007
In the British Medical Journal, a senior doctor advises caution over the use of the antiviral drug oseltamivir (Tamiflu). His concern follows advice by the Japanese authorities in March 2007 against prescribing oseltamivir to adolescents after the separate suicides of two 14 year olds who jumped to their deaths while taking the drug ... So far, oseltamivir has been thought to be well tolerated and safe, but the recent events in Japan have prompted a reappraisal, writes Simon Maxwell from the... (Science Daily)
Welsh couple face tests after outbreak of bird flu May 25, 2007
Nevertheless, because of this incident, both of these individuals are on treatment courses of oseltamivir, which is often known as Tamiflu. Dr Simmons said that enough Tamiflu to treat a quarter of the population of Wales had been moved to the area in case the disease spread. (ic Wales)
Roche ready to scale back Tamiflu production plans May 24, 2007
Tamiflu, or the basic ingredient oseltamivir, has been used extensively to treat human cases of the most virulent H5N1 strain of bird flu ... Oseltamivir has been favoured by the WHO in pandemic preparations for technical reasons. (Yahoo News -- Pharmaceutical Industry News)
Japan to check more flu drugs for side effects May 17, 2007
Tamiflu, known genetically as oseltamivir, can treat the symptoms of regular seasonal influenza and it is seen as one of the best defenses against a possible bird flu pandemic. MORE FROM COLD AND FLU. (MSNBC -- Health)
Indonesia sends 3 bird flu specimens to WHO but impasse not solved May 17, 2007
That work looks for signs of mutations that might suggest the viruses are acquiring the ability to more easily infect people or are becoming resistant to flu drugs such at oseltamivir (sold as Tamiflu). The WHO influenza surveillance program, which has been in existence for more than 50 years, operates on a principle of free sharing. (Canada.com)
Indonesia resumes sending bird flu samples to WHO May 16, 2007
That work looks for signs of mutations that might suggest the virus is acquiring the ability to more easily infect people or is becoming resistant to flu drugs such at oseltamivir (sold as Tamiflu). Poor countries provide virus samples that are used to develop commercial vaccines, but often cannot afford to buy the vaccines, said Supari. (Xinhuanet, China)
ANX-201 Drug Combination Demonstrates Synergistic Activity Against Human and Bird Flu Viruses May 3, 2007
ADVENTRX Presents Results at International Conference on Antiviral Research SAN DIEGO, May 3 /PRNewswire-FirstCall/ -- ADVENTRX Pharmaceuticals, Inc. (Amex: ), a biopharmaceutical research and development company focused on commercializing proprietary product candidates for the treatment of cancer and infectious diseases, announced today that it presented results demonstrating synergistic activity against human and avian influenza (bird flu) viruses when the Company's broad-spectrum antiviral... (PR Newswire)
Roche says Tamiflu capacity outstrips demand Apr 29, 2007
Tamiflu, known generically as oseltamivir, can treat the symptoms of regular seasonal influenza and it is the drug recommended for use in case of a pandemic of flu. Experts say a pandemic is inevitable, but they cannot predict when, or which strain of flu might be the cause. (Reuters AlertNet)
Tamiflu Best for Bird Flu, but Avoid Steroids Apr 24, 2007
The WHO reaffirmed that early treatment with Tamiflu, made by Swiss-based Roche and known generically as oseltamivir, was useful in reducing death from the H5N1 virus. Giving it to people with advanced symptoms was also "warranted". (MEDLINEplus)
China to send bird flu samples to WHO Apr 21, 2007
Also Friday, WHO said bird flu patients who received early treatment with the antiviral drug oseltamivir (Tamiflu) showed better odds of surviving, and corticocosteroids may harm H5N1 patients, based on the preliminary conclusions of international experts ... Early treatment with oseltamivir seemed to reduce the risk of death in H5N1 infections and its use is warranted for late treatment, according to the summary of the WHO-sponsored meeting last month Antalya, Turkey. (CBC News)
WHO dispenses new advice on treating bird flu Apr 20, 2007
Early treatment with the antiviral drug oseltamivir (Tamiflu) seems to reduce the risk of death in H5N1 infections ... A decision to alter oseltamivir treatment should be made on a case-by-case basis, the WHO said, asking doctors to collect data while they do it to help answer questions about whether these types of approaches are effective. (Globe and Mail)
Which cold & flu remedies work? Apr 20, 2007
However, there is a new antiviral medication, Tamiflu (oseltamivir) which gets rid of the actual virus, says general practitioner Dr Rosamund Carey. This medicine can be used if you feel flu coming on or if you are already suffering from the symptoms of flu. (iAfrica.com)
Some Drug Resistance To Influenza B Medications Apr 10, 2007
Two antiviral drugs, zanamivir and oseltamivir, which are a type of drugs known as neuraminidase inhibitors, have been effective against influenza and are used extensively. There has been documented evidence of the emergence of oseltamivir-resistant type A viruses, but similar information on influenza B viruses has been limited ... D., of the University of Tokyo, Japan, and colleagues examined the prevalence and transmissibility of influenza B viruses with reduced sensitivity to neuraminidase... (Science Daily)
More data support Tamiflu-linked abnormalities Apr 7, 2007
The 128 cases are among 1,079 suspected incidences of side effects reported to the ministry due to the oral antiviral drug -- generically known as oseltamivir phosphate -- manufactured by Switzerland's Roche pharmaceutical group. The abnormalities were reported at a meeting of the ministry's food and drug safety panel convened to examine if causal links between the drug and the strange behavior. (The Japan Times)
Flu Showing Signs Of Resistance To Antivirals Apr 7, 2007
A new research study in Japan suggests that Influenza B is becoming resistant to two antivirals commonly used to protect against flu, zanamivir (brand name Relenza) and oseltamivir (Tamiflu) ... Studies have already shown that Influenza A is becoming resistant to oseltamivir (Tamiflu), but this is the first documented evidence of Influenza B starting to do the same ... Dr Hatakeyama and colleagues took before and after samples from 74 children who were treated with oseltamivir (Tamiflu) in the... (Medical News Today)
Cambodia, Egypt report H5N1 cases; Indonesia demands vaccine Apr 7, 2007
She was treated with oseltamivir and was in stable condition, the story said. The patient had been in contact with birds suspected of infection with H5N1, AFP reported. (CIDRAP)
Study Finds Some Resistance to Flu Drugs Apr 5, 2007
The two drugs, zanamivir (Relenza) and oseltamivir (Tamiflu), have been effective against the flu and are widely used, particularly in Japan, according to the report in the April 4 issue of the Journal of the American Medical Association. "We are concerned about emerging resistance patterns through overuse of these drugs," said Dr. Marc Siegel, a clinical associate professor of medicine at New York University School of Medicine. (MEDLINEplus)
