Vitamin D May Halt Lung Function Decline In Asthma And COPD May 22, 2009
The group found that calcitriol, a form of vitamin D synthesized within the body, reduced growth-factor-induced HASM proliferation in cells isolated from both persons with asthma and from persons without the disease ... "Calcitriol has recently earned prominence for its anti-inflammatory effects," said Gautam Damera, Ph ... "But our study is the first to reveal the potent role of calcitriol in inhibiting ASM proliferation.". (Science Daily)
Summer Time Is Sun Time for Vitamin... May 20, 2009
" This was quoted as a direct reference to the sun's importance regarding vitamin D in his 02/02/05 article featured on Dr. Mercola's website . How Sunlight Helps Create Vitamin D Vitamin D is actually not a vitamin. That label was assigned out of ignorance in the early 1900's and has stuck since then. Because it can be created by the skin's exposure to the sun and then distributed throughout the body's organisms, it is technically a prehormone. According to the article by Dr. Cannell, first... (Suite101.com)
Boosting bone density Apr 29, 2009
The medicines available include vitamins, minerals, calcitriol, hormone therapy (HT), selective oestrogen receptor modulators (SERMS), bisphosphonates and recombinant parathyroid hormone ... Calcitriol is a synthetic form of vitamin D used to treat osteoporosis ... Calcitriol increases intestinal calcium absorption, regulates bone mineralisation and the production of bone proteins. (The Star Online, Malaysia)
Product Shifts are Occurring in the Renal Anemia and Bone and Mineral Metabolism Markets According to the Most Recent TreatmentTrends(R): US Nephrology Report from BioTrends Research Group Apr 28, 2009
Abbott's Zemplar continues to hold the position of market leader among hemodialysis patients, and in a shift from the same quarter last year when calcitriol was the market leader in CKD, Zemplar now holds that position. Nephrologists report that barriers to increased use of both Zemplar and Genzyme's Hectorol in CKD center around reimbursement and incidences of hypercalcemia and hyperphosphatemia. (PR Newswire)
Canine Lyme Disease Nephritis Mar 7, 2009
A Rare Fatal Complication of Lyme Disease in Dogs. Though the most common symptom of Lyme disease in dogs is lameness, Lyme disease can sometimes affect the kidneys, causing renal failure and eventually death. (Suite101.com)
Shedding light on vitamin D deficiency crisis Feb 7, 2009
It was later found that certain wavelengths of ultraviolet light prompt our bodies to synthesize vitamin D, eventually making a hormone called calcitriol that, among other things, controls how the body uses calcium and mineralizes bone. Discuss on Newsvine. (MSNBC -- Health)
Attention to Bones Important in Women with Lupus Feb 7, 2009
Yeap's team assessed changes over 2 years in bone mineral density (BMD) in 98 premenopausal women with SLE on long-term steroid therapy while taking calcium only, calcium plus calcitriol (the active form of vitamin D) or calcium plus the bone-strengthening drug alendronate (Fosamax) ... In contrast, there were no significant changes found in the calcium-only and the calcium plus calcitriol groups, except for a 0. (MEDLINEplus)
Vectical Ointment Approved for Psoriasis Feb 7, 2009
WEDNESDAY, Feb. 4 (HealthDay News) -- Galderma Laboratories' Vectical (calcitriol) ointment has been approved by the U.S. Food and Drug Administration to treat mild-to-moderate plaque psoriasis in adults, the company said. Approval was based on two eight-week studies involving more than 800 people. (MEDLINEplus)
Story ideas from the Journal of Lipid Research Mar 15, 2008
Derivatives of lithocholic acid can activate the same receptor as calcitriol, the active form of vitamin D, without affecting blood calcium levels. Bile Acids as Drug Candidates. (EurekAlert!)
OUR OPINION: State board makes right call on Senate proposal Aug 25, 2007
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Protein Marker For Prostate Cancer Survival Identified Jun 4, 2007
The finding that higher CRP is associated with shorter survival and a lower probability of response to chemotherapy is a result of a secondary analysis of inflammatory markers in subjects enrolled in the ASCENT study, a large Phase 2 clinical trial that evaluated treatment with docetaxel and DN-101, a high dose formulation of calcitriol or docetaxel with placebo. This analysis included subjects from both groups. (Science Daily)
Small biotech firm Novacea lands big partner May 31, 2007
Asentar is a high-dose formulation of the hormone calcitriol, which activates molecular processes that lead to cell death. The compound seems to enhance the power of other chemotherapy drugs such as Taxotere to kill cancer cells, Walker said. (San Francisco Chronicle -- Business)
Hormone May Foil Osteoporosis Treatment May 26, 2007
To investigate whether this might affect response to osteoporosis treatment, the researchers compared 91 women who received weekly treatment with alendronate or alendronate plus a vitamin D supplement known as calcitriol. Women taking calcitriol showed significantly greater increases in bone mineral density than those who weren't given the vitamin ... Among the women who didn't take calcitriol, there was no change in average parathyroid hormone levels, but those who did take the vitamin showed... (MEDLINEplus)
Recombinant PTH for Initial Management of Neonatal Hypocalcemia Apr 19, 2007
Currently, initial management consists of the administration of calcitriol and high doses of calcium. In symptomatic children, to avoid extravasation, intravenous calcium is best administered through a central line, a procedure that requires proper expertise. (New England Journal of Medicine)
Calcitriol Lowers Risk of Falls in Elderly Women Feb 13, 2007
NEW YORK (Reuters Health) - In elderly women with reduced kidney function, treatment with calcitriol, the active form of vitamin D, appears to offer protection against falls, researchers report ... Calcitriol reduced falls by 50 percent in women over age 65 and particularly in those with reduced kidney function ... Gallagher of Creighton University Medical Center, Omaha, Nebraska and colleagues randomly allocated 415 women aged 65 to 77 years to calcitriol (0. (MEDLINEplus)
Vitamin D protects the skin? Jan 30, 2007
found that vitamin D3 generated under the skin by the sun's ultraviolet rays can be converted into its active form, calcitriol (1,25 dihydroxy-vitamin D3), by enzymes in the liver and kidneys. The new study shows that human dendritic cells could accomplish the same conversion without involving the endocrine system at all. (The Scientist)
