fat is an angry substance Nov 17, 2009
Calcitriol (the active form of vitamin D) has been shown in vivo to reduce inflammation (by suppressing cytokine cross-talk), aid macrophages digest cholesterol and improve insulin sensitivity. Oh yeah, and calcitriol "inhibits TLR expression" ... Calcitriol, the active hormone made from vitamin D3, enhances innate immunity by up regulating the cathelicidin antimicrobial peptide (hCAP). (Harper's Magazine)
Over 65? Take Lots of Vitamin D to Prevent a Fall Oct 6, 2009
While vitamin D3 seemed more potent than D2, forms of vitamin D marketed as "active," such as calcitriol, did not seem to be more effective than standard vitamin D supplements, the researchers found. Such active forms are more expensive and carry a higher risk of elevated calcium levels, which have been linked to hormone problems and cancer. (MEDLINEplus)
Top Poisons That Can Harm Pets Sep 30, 2009
Even small exposures to Vitamin D analogues like calcipotriene and calcitriol can cause life-threatening spikes in blood calcium levels in pets. Clinical signs of exposure-including vomiting, loss of appetite, increased urination and thirst due to kidney failure-often don't occur for more than 24 hours after ingestion. (W-USA News, DC)
Nephrologists Indicate High Interest in AMAG Pharmaceuticals' Newly Approved Feraheme According to Latest BioTrends Report Aug 5, 2009
Hectorol PO also declined year over year, but together these newer analogues still account for roughly half of the CKD patient share while calcitriol remains the market share leader. The next wave of TreatmentTrends(R): US Nephrology will field in late August in tandem with surveys directed at two ancillary renal care audiences, Anemia Managers and Renal Dietitians. (PR Newswire)
Vitamin D May Halt Lung Function Decline In Asthma And COPD May 22, 2009
The group found that calcitriol, a form of vitamin D synthesized within the body, reduced growth-factor-induced HASM proliferation in cells isolated from both persons with asthma and from persons without the disease ... "Calcitriol has recently earned prominence for its anti-inflammatory effects," said Gautam Damera, Ph ... "But our study is the first to reveal the potent role of calcitriol in inhibiting ASM proliferation.". (Science Daily)
Summer Time Is Sun Time for Vitamin... May 20, 2009
" This was quoted as a direct reference to the sun's importance regarding vitamin D in his 02/02/05 article featured on Dr. Mercola's website . How Sunlight Helps Create Vitamin D Vitamin D is actually not a vitamin. That label was assigned out of ignorance in the early 1900's and has stuck since then. Because it can be created by the skin's exposure to the sun and then distributed throughout the body's organisms, it is technically a prehormone. According to the article by Dr. Cannell, first... (Suite101.com)
Boosting bone density Apr 29, 2009
The medicines available include vitamins, minerals, calcitriol, hormone therapy (HT), selective oestrogen receptor modulators (SERMS), bisphosphonates and recombinant parathyroid hormone ... Calcitriol is a synthetic form of vitamin D used to treat osteoporosis ... Calcitriol increases intestinal calcium absorption, regulates bone mineralisation and the production of bone proteins. (The Star Online, Malaysia)
Product Shifts are Occurring in the Renal Anemia and Bone and Mineral Metabolism Markets According to the Most Recent TreatmentTrends(R): US Nephrology Report from BioTrends Research Group Apr 28, 2009
Abbott's Zemplar continues to hold the position of market leader among hemodialysis patients, and in a shift from the same quarter last year when calcitriol was the market leader in CKD, Zemplar now holds that position. Nephrologists report that barriers to increased use of both Zemplar and Genzyme's Hectorol in CKD center around reimbursement and incidences of hypercalcemia and hyperphosphatemia. (PR Newswire)
Canine Lyme Disease Nephritis Mar 7, 2009
A Rare Fatal Complication of Lyme Disease in Dogs. Though the most common symptom of Lyme disease in dogs is lameness, Lyme disease can sometimes affect the kidneys, causing renal failure and eventually death. (Suite101.com)
Attention to Bones Important in Women with Lupus Feb 7, 2009
Yeap's team assessed changes over 2 years in bone mineral density (BMD) in 98 premenopausal women with SLE on long-term steroid therapy while taking calcium only, calcium plus calcitriol (the active form of vitamin D) or calcium plus the bone-strengthening drug alendronate (Fosamax) ... In contrast, there were no significant changes found in the calcium-only and the calcium plus calcitriol groups, except for a 0. (MEDLINEplus)
Vectical Ointment Approved for Psoriasis Feb 7, 2009
WEDNESDAY, Feb. 4 (HealthDay News) -- Galderma Laboratories' Vectical (calcitriol) ointment has been approved by the U.S. Food and Drug Administration to treat mild-to-moderate plaque psoriasis in adults, the company said. Approval was based on two eight-week studies involving more than 800 people. (MEDLINEplus)
Shedding light on vitamin D deficiency crisis Feb 7, 2009
It was later found that certain wavelengths of ultraviolet light prompt our bodies to synthesize vitamin D, eventually making a hormone called calcitriol that, among other things, controls how the body uses calcium and mineralizes bone. Discuss on Newsvine. (MSNBC -- Health)
